ES2003176A6 - Procedimiento para preparar derivados de 4h-benzo(4,5)ciclohepta(1,2-b)tiofeno - Google Patents
Procedimiento para preparar derivados de 4h-benzo(4,5)ciclohepta(1,2-b)tiofenoInfo
- Publication number
- ES2003176A6 ES2003176A6 ES8603303A ES8603303A ES2003176A6 ES 2003176 A6 ES2003176 A6 ES 2003176A6 ES 8603303 A ES8603303 A ES 8603303A ES 8603303 A ES8603303 A ES 8603303A ES 2003176 A6 ES2003176 A6 ES 2003176A6
- Authority
- ES
- Spain
- Prior art keywords
- cyclohepta
- benzo
- thiophene derivatives
- salts
- esters
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
- C07D333/80—Seven-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR DERIVADOS DE 4H©BENZO[4,5] CICLOHEPTA [1,2©B]TIOFENO, DE FORMULA (I) EN DONDE R1 ES HIDROGENO O ALQUILO C1©C4 Y R2 ES HALOGENO, O UN ESTER FISIOLOGICAMENTE HIDROLIZABLE Y ACEPTABLE O UNA SAL DE DICHO COMPUESTO. COMPRENDE REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III); O HIDROLIZAR UN COMPUESTO DE FORMULA (IA); O SOMETER A ESCISION DE ETER UN COMPUESTO DE FORMULA (I) O (IA). LOS COMPUESTOS (I) POSEEN ACTIVIDAD FARMACOLOGICA Y SE PUEDEN USAR COMO FARMACOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB858530245A GB8530245D0 (en) | 1985-12-09 | 1985-12-09 | Organic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2003176A6 true ES2003176A6 (es) | 1988-10-16 |
Family
ID=10589437
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8603303A Expired ES2003176A6 (es) | 1985-12-09 | 1986-12-05 | Procedimiento para preparar derivados de 4h-benzo(4,5)ciclohepta(1,2-b)tiofeno |
Country Status (23)
Country | Link |
---|---|
US (1) | US4775691A (es) |
JP (1) | JPS62149672A (es) |
AT (1) | ATA323986A (es) |
AU (1) | AU600243B2 (es) |
BE (1) | BE905872A (es) |
CA (1) | CA1276158C (es) |
CH (1) | CH672129B (es) |
DE (1) | DE3641907A1 (es) |
DK (1) | DK589886A (es) |
ES (1) | ES2003176A6 (es) |
FI (1) | FI864978A (es) |
FR (1) | FR2595359B1 (es) |
GB (2) | GB8530245D0 (es) |
GR (1) | GR862863B (es) |
HU (1) | HU202858B (es) |
IL (1) | IL80906A (es) |
IT (1) | IT1214756B (es) |
LU (1) | LU86706A1 (es) |
NL (1) | NL8603098A (es) |
NZ (1) | NZ218547A (es) |
PH (1) | PH24024A (es) |
SE (1) | SE8605255L (es) |
ZA (1) | ZA869296B (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU203198B (en) * | 1987-10-26 | 1991-06-28 | Sandoz Ag | Process for producing pharmaceutical compositions having immunity-inhibiting, monokin-, particularly interleukin-1-inhibiting effect |
GB9010332D0 (en) * | 1990-05-09 | 1990-06-27 | Sandoz Ltd | Improvements in or relating to organic compounds |
JP2005536518A (ja) * | 2002-07-19 | 2005-12-02 | ファルマシア コーポレイション | 炎症治療のための置換チオフェンカルボキサミド化合物 |
US7982032B2 (en) * | 2004-03-11 | 2011-07-19 | Sun Pharmaceutical Industries Limited | Process for the preparation of 10,11-dihydro-10-oxo-5H-dibenz[b,f]azepine-5-carboxamide |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH473823A (de) * | 1964-08-11 | 1969-06-15 | Sandoz Ag | Verfahren zur Herstellung von neuen 4H-Benzo(4,5)cyclohepta(1,2-b)thiophen-Derivaten |
US4137323A (en) * | 1973-10-10 | 1979-01-30 | Sandoz Ltd. | Organic compounds |
DK44278A (da) * | 1977-02-08 | 1978-08-09 | Sandoz Ag | Fremgangsmaade til fremstilling af thiophenderivater |
US4496580A (en) * | 1981-07-23 | 1985-01-29 | Hoechst-Roussel Pharmaceuticals Inc. | Oxothienobenzoxepins |
US4487778A (en) * | 1983-01-27 | 1984-12-11 | Fmc Corporation | Insecticidal esters derived from benzocycloalkane-thiophenemethyl compounds |
HU195800B (en) * | 1983-10-13 | 1988-07-28 | Sandoz Ltd | Process for producing 4h-benzo/4,5/cylopenta/1,2-b/ thiofene derivatives and pharmaceutical compositions containing them |
-
1985
- 1985-12-09 GB GB858530245A patent/GB8530245D0/en active Pending
-
1986
- 1986-12-03 CH CH482386A patent/CH672129B/de unknown
- 1986-12-05 ES ES8603303A patent/ES2003176A6/es not_active Expired
- 1986-12-05 AT AT0323986A patent/ATA323986A/de not_active Application Discontinuation
- 1986-12-05 GB GB8629130A patent/GB2183648B/en not_active Expired
- 1986-12-05 NL NL8603098A patent/NL8603098A/nl not_active Application Discontinuation
- 1986-12-08 JP JP61292269A patent/JPS62149672A/ja active Granted
- 1986-12-08 NZ NZ218547A patent/NZ218547A/xx unknown
- 1986-12-08 DE DE19863641907 patent/DE3641907A1/de not_active Withdrawn
- 1986-12-08 IL IL80906A patent/IL80906A/xx not_active IP Right Cessation
- 1986-12-08 FI FI864978A patent/FI864978A/fi not_active IP Right Cessation
- 1986-12-08 CA CA000524731A patent/CA1276158C/en not_active Expired - Lifetime
- 1986-12-08 LU LU86706A patent/LU86706A1/fr unknown
- 1986-12-08 SE SE8605255A patent/SE8605255L/xx not_active Application Discontinuation
- 1986-12-08 GR GR862863A patent/GR862863B/el unknown
- 1986-12-08 AU AU66175/86A patent/AU600243B2/en not_active Ceased
- 1986-12-08 DK DK589886A patent/DK589886A/da not_active Application Discontinuation
- 1986-12-08 FR FR8617118A patent/FR2595359B1/fr not_active Expired
- 1986-12-08 BE BE905872A patent/BE905872A/fr unknown
- 1986-12-08 PH PH34565A patent/PH24024A/en unknown
- 1986-12-09 ZA ZA869296A patent/ZA869296B/xx unknown
- 1986-12-09 IT IT8648725A patent/IT1214756B/it active
-
1987
- 1987-01-15 HU HU87113A patent/HU202858B/hu unknown
-
1988
- 1988-01-20 US US07/145,870 patent/US4775691A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
PH24024A (en) | 1990-02-09 |
DE3641907A1 (de) | 1987-06-11 |
GB8530245D0 (en) | 1986-01-22 |
CA1276158C (en) | 1990-11-13 |
IT8648725A0 (it) | 1986-12-09 |
GR862863B (en) | 1987-04-09 |
NZ218547A (en) | 1990-03-27 |
DK589886D0 (da) | 1986-12-08 |
FI864978A (fi) | 1987-06-10 |
SE8605255D0 (sv) | 1986-12-08 |
FR2595359B1 (fr) | 1989-08-18 |
SE8605255L (sv) | 1987-06-10 |
ATA323986A (de) | 1992-09-15 |
AU6617586A (en) | 1987-06-11 |
HU202858B (en) | 1991-04-29 |
FI864978A0 (fi) | 1986-12-08 |
DK589886A (da) | 1987-06-10 |
CH672129B (es) | 1989-10-31 |
BE905872A (fr) | 1987-06-09 |
AU600243B2 (en) | 1990-08-09 |
LU86706A1 (fr) | 1987-07-24 |
US4775691A (en) | 1988-10-04 |
GB2183648B (en) | 1989-10-18 |
IT1214756B (it) | 1990-01-18 |
GB8629130D0 (en) | 1987-01-14 |
IL80906A0 (en) | 1987-03-31 |
FR2595359A1 (fr) | 1987-09-11 |
JPS62149672A (ja) | 1987-07-03 |
JPH0422912B2 (es) | 1992-04-20 |
IL80906A (en) | 1991-01-31 |
HUT46903A (en) | 1988-12-28 |
GB2183648A (en) | 1987-06-10 |
NL8603098A (nl) | 1987-07-01 |
ZA869296B (en) | 1988-07-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
SA6 | Expiration date (snapshot 920101) |
Free format text: 2006-12-05 |
|
FD1A | Patent lapsed |
Effective date: 20010503 |