ES2003176A6 - Procedimiento para preparar derivados de 4h-benzo(4,5)ciclohepta(1,2-b)tiofeno - Google Patents

Procedimiento para preparar derivados de 4h-benzo(4,5)ciclohepta(1,2-b)tiofeno

Info

Publication number
ES2003176A6
ES2003176A6 ES8603303A ES8603303A ES2003176A6 ES 2003176 A6 ES2003176 A6 ES 2003176A6 ES 8603303 A ES8603303 A ES 8603303A ES 8603303 A ES8603303 A ES 8603303A ES 2003176 A6 ES2003176 A6 ES 2003176A6
Authority
ES
Spain
Prior art keywords
cyclohepta
benzo
thiophene derivatives
salts
esters
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8603303A
Other languages
English (en)
Inventor
Albert Leutwiler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES2003176A6 publication Critical patent/ES2003176A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • C07D333/80—Seven-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR DERIVADOS DE 4H©BENZO[4,5] CICLOHEPTA [1,2©B]TIOFENO, DE FORMULA (I) EN DONDE R1 ES HIDROGENO O ALQUILO C1©C4 Y R2 ES HALOGENO, O UN ESTER FISIOLOGICAMENTE HIDROLIZABLE Y ACEPTABLE O UNA SAL DE DICHO COMPUESTO. COMPRENDE REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III); O HIDROLIZAR UN COMPUESTO DE FORMULA (IA); O SOMETER A ESCISION DE ETER UN COMPUESTO DE FORMULA (I) O (IA). LOS COMPUESTOS (I) POSEEN ACTIVIDAD FARMACOLOGICA Y SE PUEDEN USAR COMO FARMACOS.
ES8603303A 1985-12-09 1986-12-05 Procedimiento para preparar derivados de 4h-benzo(4,5)ciclohepta(1,2-b)tiofeno Expired ES2003176A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858530245A GB8530245D0 (en) 1985-12-09 1985-12-09 Organic compounds

Publications (1)

Publication Number Publication Date
ES2003176A6 true ES2003176A6 (es) 1988-10-16

Family

ID=10589437

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8603303A Expired ES2003176A6 (es) 1985-12-09 1986-12-05 Procedimiento para preparar derivados de 4h-benzo(4,5)ciclohepta(1,2-b)tiofeno

Country Status (23)

Country Link
US (1) US4775691A (es)
JP (1) JPS62149672A (es)
AT (1) ATA323986A (es)
AU (1) AU600243B2 (es)
BE (1) BE905872A (es)
CA (1) CA1276158C (es)
CH (1) CH672129B (es)
DE (1) DE3641907A1 (es)
DK (1) DK589886A (es)
ES (1) ES2003176A6 (es)
FI (1) FI864978A (es)
FR (1) FR2595359B1 (es)
GB (2) GB8530245D0 (es)
GR (1) GR862863B (es)
HU (1) HU202858B (es)
IL (1) IL80906A (es)
IT (1) IT1214756B (es)
LU (1) LU86706A1 (es)
NL (1) NL8603098A (es)
NZ (1) NZ218547A (es)
PH (1) PH24024A (es)
SE (1) SE8605255L (es)
ZA (1) ZA869296B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU203198B (en) * 1987-10-26 1991-06-28 Sandoz Ag Process for producing pharmaceutical compositions having immunity-inhibiting, monokin-, particularly interleukin-1-inhibiting effect
GB9010332D0 (en) * 1990-05-09 1990-06-27 Sandoz Ltd Improvements in or relating to organic compounds
JP2005536518A (ja) * 2002-07-19 2005-12-02 ファルマシア コーポレイション 炎症治療のための置換チオフェンカルボキサミド化合物
US7982032B2 (en) * 2004-03-11 2011-07-19 Sun Pharmaceutical Industries Limited Process for the preparation of 10,11-dihydro-10-oxo-5H-dibenz[b,f]azepine-5-carboxamide

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH473823A (de) * 1964-08-11 1969-06-15 Sandoz Ag Verfahren zur Herstellung von neuen 4H-Benzo(4,5)cyclohepta(1,2-b)thiophen-Derivaten
US4137323A (en) * 1973-10-10 1979-01-30 Sandoz Ltd. Organic compounds
DK44278A (da) * 1977-02-08 1978-08-09 Sandoz Ag Fremgangsmaade til fremstilling af thiophenderivater
US4496580A (en) * 1981-07-23 1985-01-29 Hoechst-Roussel Pharmaceuticals Inc. Oxothienobenzoxepins
US4487778A (en) * 1983-01-27 1984-12-11 Fmc Corporation Insecticidal esters derived from benzocycloalkane-thiophenemethyl compounds
HU195800B (en) * 1983-10-13 1988-07-28 Sandoz Ltd Process for producing 4h-benzo/4,5/cylopenta/1,2-b/ thiofene derivatives and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
PH24024A (en) 1990-02-09
DE3641907A1 (de) 1987-06-11
GB8530245D0 (en) 1986-01-22
CA1276158C (en) 1990-11-13
IT8648725A0 (it) 1986-12-09
GR862863B (en) 1987-04-09
NZ218547A (en) 1990-03-27
DK589886D0 (da) 1986-12-08
FI864978A (fi) 1987-06-10
SE8605255D0 (sv) 1986-12-08
FR2595359B1 (fr) 1989-08-18
SE8605255L (sv) 1987-06-10
ATA323986A (de) 1992-09-15
AU6617586A (en) 1987-06-11
HU202858B (en) 1991-04-29
FI864978A0 (fi) 1986-12-08
DK589886A (da) 1987-06-10
CH672129B (es) 1989-10-31
BE905872A (fr) 1987-06-09
AU600243B2 (en) 1990-08-09
LU86706A1 (fr) 1987-07-24
US4775691A (en) 1988-10-04
GB2183648B (en) 1989-10-18
IT1214756B (it) 1990-01-18
GB8629130D0 (en) 1987-01-14
IL80906A0 (en) 1987-03-31
FR2595359A1 (fr) 1987-09-11
JPS62149672A (ja) 1987-07-03
JPH0422912B2 (es) 1992-04-20
IL80906A (en) 1991-01-31
HUT46903A (en) 1988-12-28
GB2183648A (en) 1987-06-10
NL8603098A (nl) 1987-07-01
ZA869296B (en) 1988-07-27

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Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2006-12-05

FD1A Patent lapsed

Effective date: 20010503