ES2001573A6 - Un procedimiento para preparar acidos ciclohexanoalcanoicos sustituidos - Google Patents

Un procedimiento para preparar acidos ciclohexanoalcanoicos sustituidos

Info

Publication number
ES2001573A6
ES2001573A6 ES8601313A ES8601313A ES2001573A6 ES 2001573 A6 ES2001573 A6 ES 2001573A6 ES 8601313 A ES8601313 A ES 8601313A ES 8601313 A ES8601313 A ES 8601313A ES 2001573 A6 ES2001573 A6 ES 2001573A6
Authority
ES
Spain
Prior art keywords
present
acids
compounds
esters
cyclohexanealkanoic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8601313A
Other languages
English (en)
Inventor
Robert Cregge
Jeffrey S Sabol
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Publication of ES2001573A6 publication Critical patent/ES2001573A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/132—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing rings
    • C07C53/134—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing rings monocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C323/11—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/16—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/38—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D303/40—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by ester radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Abstract

UN PROCEDIMIENTO PARA PREPARAR ACIDOS CICLOHEXANOALCANOICOS SUSTITUIDOS. LOS COMPUESTOS DE FORMULA (I) EN LOS QUE M ES UN ENTERO DE 1 A 5, N ES UN ENTERO DE 0 A 2 Y R, X Y Y Z REPRESENTAN VARIOS RADICALES, SE PREPARAN POR REACCION DE UN EPOXITO DE FORMULA (II) CON UN DERIVADO DE ACIDO MERCAPTOALCANOICO DE FORMULA (III), EN UN DISOLVENTE APROPIADO Y EN PRESENCIA DE UNA BASE, SEGUIDO OPCIONALMENTE, CUANDO YK, YL O ZK SON -O-(ALQUILO INFERIOR) DE TRATAMIENTO CON UNA BASE INORGANICA FUERTE SEGUIDA DE ACIDULACION CON UN ACIDO FUERTE PARA DAR LOS COMPUESTOS DONDE Y, YL O Z SON -OH. ESTOS COMPUESTOS SON UTILES PARA EL TRATAMIENTO DE ENFERMEDADES ALERGICAS Y, EN PARTICULAR, DEL ASMA BRONQUIAL.
ES8601313A 1985-08-23 1986-08-22 Un procedimiento para preparar acidos ciclohexanoalcanoicos sustituidos Expired ES2001573A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/768,769 US4622422A (en) 1985-08-23 1985-08-23 Cyclohexanealkanoic acids

Publications (1)

Publication Number Publication Date
ES2001573A6 true ES2001573A6 (es) 1988-06-01

Family

ID=25083435

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8601313A Expired ES2001573A6 (es) 1985-08-23 1986-08-22 Un procedimiento para preparar acidos ciclohexanoalcanoicos sustituidos

Country Status (21)

Country Link
US (1) US4622422A (es)
EP (1) EP0213547B1 (es)
JP (1) JPS6248663A (es)
KR (1) KR900002821B1 (es)
CN (1) CN1019195B (es)
AR (1) AR241179A1 (es)
AT (1) ATE59382T1 (es)
AU (1) AU605466B2 (es)
CA (1) CA1283250C (es)
DE (1) DE3676594D1 (es)
DK (1) DK401786A (es)
ES (1) ES2001573A6 (es)
FI (1) FI84263C (es)
GR (1) GR862164B (es)
HU (1) HU196744B (es)
IL (1) IL79770A0 (es)
NO (1) NO164533C (es)
NZ (1) NZ217249A (es)
PH (1) PH22129A (es)
PT (1) PT83238B (es)
ZA (1) ZA866216B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4748274A (en) * 1986-11-07 1988-05-31 Merrell Dow Pharmaceuticals Inc. 4-hydroxy-4-(substituted alkenyl)cyclohexanecarboxylic acids
US6863111B1 (en) 2000-10-03 2005-03-08 Tser-Wen Chou Positive engagement end stop for window covering systems
JP4746511B2 (ja) * 2006-10-23 2011-08-10 株式会社東芝 固体高分子型燃料電池システム

Also Published As

Publication number Publication date
AU605466B2 (en) 1991-01-17
DE3676594D1 (de) 1991-02-07
US4622422A (en) 1986-11-11
JPS6248663A (ja) 1987-03-03
DK401786D0 (da) 1986-08-22
EP0213547A1 (en) 1987-03-11
PT83238B (pt) 1988-07-01
KR870002068A (ko) 1987-03-28
ZA866216B (en) 1987-03-25
FI84263C (fi) 1991-11-11
PH22129A (en) 1988-06-01
NZ217249A (en) 1989-11-28
AR241179A1 (es) 1992-01-31
CA1283250C (en) 1991-04-16
GR862164B (en) 1986-12-23
FI863410A (fi) 1987-02-24
NO164533C (no) 1990-10-17
NO863388L (no) 1987-02-24
ATE59382T1 (de) 1991-01-15
CN1019195B (zh) 1992-11-25
HU196744B (en) 1989-01-30
FI84263B (fi) 1991-07-31
KR900002821B1 (ko) 1990-05-01
IL79770A0 (en) 1986-11-30
HUT43813A (en) 1987-12-28
CN86105165A (zh) 1987-04-08
NO863388D0 (no) 1986-08-22
FI863410A0 (fi) 1986-08-22
PT83238A (en) 1986-09-01
NO164533B (no) 1990-07-09
AU6164786A (en) 1987-02-26
DK401786A (da) 1987-02-24
EP0213547B1 (en) 1990-12-27

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