ES2000602A6 - Procedimiento para la preparacion de nuevos peptidos relacionados con la calcitonina - Google Patents

Procedimiento para la preparacion de nuevos peptidos relacionados con la calcitonina

Info

Publication number
ES2000602A6
ES2000602A6 ES8600959A ES8600959A ES2000602A6 ES 2000602 A6 ES2000602 A6 ES 2000602A6 ES 8600959 A ES8600959 A ES 8600959A ES 8600959 A ES8600959 A ES 8600959A ES 2000602 A6 ES2000602 A6 ES 2000602A6
Authority
ES
Spain
Prior art keywords
related peptide
peptide derivatives
calcitonin gene
gene related
asn
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8600959A
Other languages
English (en)
Inventor
Toshiharj Noda
Nobutaka Fujii
Kaorj Morita
Masayuki Hori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Kasei Corp
Original Assignee
Toyo Jozo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyo Jozo KK filed Critical Toyo Jozo KK
Publication of ES2000602A6 publication Critical patent/ES2000602A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57527—Calcitonin gene related peptide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE NUEVOS PEPTIDOS RELACIONADOS CON LA CALCITONINA. COMPRENDE SOMETER A CONDENSACION, POR LA TECNICA DE LA FASE LIQUIDA Y/O DE LA FASE SOLIDA LOS CORRESPONDIENTES AMINOACIDOS O PEPTIDOS PARCIALES CONSTITUTIVOS DEL PEPTIDO, SEGUIDO DE ELIMINACION DE LOS GRUPOS PROTECTORES MEDIANTE HIDROLISIS, DESCOMPOSICION CON ACIDO, REDUCCION, AMINOLISIS O HIDROGENOLISIS. ESTOS PEPTIDOS SON UTILES COMO MEDICINAS O AUXILIARES DE DIAGNOSTICO CLINICO PARA EL METABOLISMO DE LOS HUESOS Y EL SISTEMA NERVIOSO CENTRAL.
ES8600959A 1985-08-09 1986-08-08 Procedimiento para la preparacion de nuevos peptidos relacionados con la calcitonina Expired ES2000602A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP17534085 1985-08-09

Publications (1)

Publication Number Publication Date
ES2000602A6 true ES2000602A6 (es) 1988-03-01

Family

ID=15994349

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8600959A Expired ES2000602A6 (es) 1985-08-09 1986-08-08 Procedimiento para la preparacion de nuevos peptidos relacionados con la calcitonina

Country Status (5)

Country Link
US (1) US4743677A (es)
EP (1) EP0212432B1 (es)
JP (1) JPS62129297A (es)
DE (1) DE3685167D1 (es)
ES (1) ES2000602A6 (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5049654A (en) * 1986-12-04 1991-09-17 Toyo Jozo Kabushiki Kaisha Calcitonin gene related peptide derivatives
JPS6426598A (en) * 1987-07-22 1989-01-27 Toyo Jozo Kk Calcitonin gene related peptide derivative
JPH02262595A (ja) * 1988-02-29 1990-10-25 Otsuka Pharmaceut Co Ltd ポリペプチド誘導体
CA2001094A1 (en) * 1988-10-20 1990-04-20 Michael A. W. Eaton Chemical compounds
DE3913954A1 (de) * 1989-04-27 1990-10-31 Stief Georg Arzneimittel zur behandlung erektiler dysfunktionen
GB8915712D0 (en) * 1989-07-08 1989-08-31 Macintyre Iain Medical treatment
WO1991007433A1 (en) * 1989-11-08 1991-05-30 Daicel Chemical Industries, Ltd. Peptide and process for preparing cyclic peptide
JPH06507602A (ja) * 1991-02-12 1994-09-01 ルミニス　ピーティーワイ　リミテッド ペプチド
WO1992015317A1 (en) * 1991-03-08 1992-09-17 Amylin Pharmaceuticals, Inc. Synthetic preparation of amylin and amylin analogues
HU222249B1 (hu) * 1991-03-08 2003-05-28 Amylin Pharmaceuticals Inc. Eljárás amilin agonista peptidszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására
EP0770623A4 (en) * 1995-03-20 2002-07-31 Kyowa Hakko Kogyo Kk INNOVATIVE CALCITON DERIVATIVES
US5962270A (en) 1996-02-06 1999-10-05 Bionebraska, Inc. Recombinant preparation of calcitonin fragments and use thereof in the preparation of calcitonin and related analogs
WO1998001133A1 (en) * 1996-07-08 1998-01-15 Yamanouchi Pharmaceutical Co., Ltd. Bone resorption inhibitors
EP1265626B1 (en) * 2000-03-14 2014-09-10 National Jewish Health Method for reducing allergen-induced airway hyperresponsiveness
KR100418962B1 (ko) * 2001-06-07 2004-02-14 김학주 2-(4-나이트로페닐설포닐)에톡시카르보닐-아미노산류를사용하여 펩티드를 고수율 및 고순도로 제조하는 방법
WO2007054809A2 (en) 2005-11-14 2007-05-18 Rinat Neuroscience Corp. Antagonist antibodies directed against calcitonin gene-related peptide and methods using same
NZ587292A (en) 2008-03-04 2012-09-28 Pfizer Ltd Use of anti-CGRP (calcitonin gene-related peptide) antagonists to treat chronic pain
RU2535074C2 (ru) 2009-08-28 2014-12-10 Лэйбрис Байолоджикс, Инк. Способы лечения висцеральной боли путем введения антител-антагонистов, направленных против пептида, связанного с геном кальцитонина
DK2709662T3 (da) 2011-05-20 2019-11-04 Alderbio Holdings Llc Anvendelse af anti-cgrp- eller anti-cgrp-r-antistoffer eller antistoffragmenter til behandling eller forebyggelse af kroniske og akutte former for diarré
EP3508501B1 (en) 2011-05-20 2024-11-06 H. Lundbeck A/S Use of anti-cgrp antibodies and antibody fragments to prevent or inhibit photophobia or light aversion in subjects in need thereof, especially migraine sufferers
SMT201900293T1 (it) 2011-05-20 2019-07-11 Alderbio Holdings Llc Composizioni comprendenti anticorpi anti-cgrp e loro utilizzo
WO2013112912A1 (en) 2012-01-26 2013-08-01 Soares Christopher J Peptide antagonists of the calcitonin cgrp family of peptide hormones and their use
US20170114122A1 (en) 2015-10-23 2017-04-27 Alderbio Holdings Llc Regulation of glucose metabolism using anti-cgrp antibodies
US10556945B2 (en) 2014-03-21 2020-02-11 Teva Pharmaceuticals International Gmbh Antagonist antibodies directed against calcitonin gene-related peptide and methods using same
CN111973740A (zh) 2014-03-21 2020-11-24 泰华制药国际有限公司 针对降钙素基因相关肽的拮抗剂抗体及其使用方法
JP7123932B2 (ja) 2016-09-02 2022-08-23 クリストファー ジェイ． ソアレス 神経保護及び神経疾患におけるｃｇｒｐ受容体アンタゴニストの使用
CA3036632A1 (en) 2016-09-23 2018-03-29 Teva Pharmaceuticals International Gmbh Treating refractory migraine
CN109406709B (zh) * 2018-12-27 2020-11-10 福建省中医药研究院(福建省青草药开发服务中心） 一种太子参药材中氨基酸类成分的薄层鉴别方法
EP3908606A4 (en) 2019-01-08 2022-11-23 H. Lundbeck A/S ACUTE TREATMENT AND RAPID TREATMENT OF HEADACHE WITH ANTI-CGRP ANTIBODIES
BR102020007149A8 (pt) 2020-04-06 2023-09-26 H Lundbeck As Usos de um anticorpo anti-cgrp ou anti-cgrp-r ou um fragmento dos mesmos para melhorar o sintoma mais incômodo (mbs) e a impressão global de mudança (pgic) associados com enxaqueca

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4514331A (en) * 1983-06-29 1985-04-30 University Patents, Inc. Peptide hormones with calcitonin-like activity
US4549986A (en) * 1983-12-23 1985-10-29 The Salk Institute For Biological Studies Human CGRP

Also Published As

Publication number Publication date
EP0212432B1 (en) 1992-05-06
EP0212432A2 (en) 1987-03-04
US4743677A (en) 1988-05-10
EP0212432A3 (en) 1989-01-25
DE3685167D1 (de) 1992-06-11
JPS62129297A (ja) 1987-06-11

Similar Documents

Publication Publication Date Title
ES2000602A6 (es) Procedimiento para la preparacion de nuevos peptidos relacionados con la calcitonina
ES2070660A1 (es) Un procedimiento para la preparacion de 2,5-damino-3-hidroxihexanos sustituidos, utiles como inhibidores de proteasas retrovirales.
NO875188D0 (no) Karbapenemderivater, fremgangsmaate til fremstilling derav, samt preparater som inneholder dem.
AU541843B2 (en) Substituted 1,2-diaminocyclobutene-3,4-diones
IL54930A (en) Herbicidal preparations containing 1,2,3-thiadiazole-5-carboxylic acid derivatives
ZA909903B (en) New compounds
EP0142335A3 (en) Lactam containing compounds
AU674839B2 (en) Pyridinecarboximidamide compound and use thereof
EP0138344A3 (en) Pyridazinones as beta-adrenoceptor antagonists
FR2471425B1 (fr) Dispositif cathodique pour four d'electrolyse ignee, notamment pour la production d'aluminium
JPS5430197A (en) Novel antibiotic compound
EP0295679A3 (en) Physiologically-active novel peptides
ES8401930A1 (es) Un procedimiento para preparar derivados de amida del acido nitrobenzoico.
AU2377177A (en) ELECTROLYTIC DIAPHRAGM v, F'r L
EP0178845A3 (en) Peptide-substituted heterocyclic immunostimulants
ZA929738B (en) New use of amino acid derivatives.
PL270981A1 (en) Pesticide containing novel derivatives of 2-phenylimidazole
ES8304548A1 (es) "procedimiento de preparacion de derivados de fenetanolamina".
NZ217778A (en) Antiinflammatory compositions containing piroxicam
FR2679259B1 (fr) Dispositif d'orientation de raccords d'anodes.
PL261454A1 (en) Herbicide containing novel 2-aryl-4,5,6,7-tetrahydroisoindolinones
ES8706138A1 (es) Procedimiento para la obtencion de nuevas benzoilureas
AU545884B2 (en) Appareil d'electrolyse
JPS5283732A (en) Haloazetidinone compounds
PH15358A (en) 3'-(substituted phenyl)-spiro-(x sobenzofuran-1(3h),5'(4'h)-isoxazol)-3-ones

Legal Events

Date Code Title Description
PC1A Transfer granted

Owner name: ASAHI KASEI KABUSHIKI KAISHA