ES2000602A6 - Procedimiento para la preparacion de nuevos peptidos relacionados con la calcitonina - Google Patents
Procedimiento para la preparacion de nuevos peptidos relacionados con la calcitoninaInfo
- Publication number
- ES2000602A6 ES2000602A6 ES8600959A ES8600959A ES2000602A6 ES 2000602 A6 ES2000602 A6 ES 2000602A6 ES 8600959 A ES8600959 A ES 8600959A ES 8600959 A ES8600959 A ES 8600959A ES 2000602 A6 ES2000602 A6 ES 2000602A6
- Authority
- ES
- Spain
- Prior art keywords
- related peptide
- peptide derivatives
- calcitonin gene
- gene related
- asn
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57527—Calcitonin gene related peptide
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Toxicology (AREA)
- General Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE NUEVOS PEPTIDOS RELACIONADOS CON LA CALCITONINA. COMPRENDE SOMETER A CONDENSACION, POR LA TECNICA DE LA FASE LIQUIDA Y/O DE LA FASE SOLIDA LOS CORRESPONDIENTES AMINOACIDOS O PEPTIDOS PARCIALES CONSTITUTIVOS DEL PEPTIDO, SEGUIDO DE ELIMINACION DE LOS GRUPOS PROTECTORES MEDIANTE HIDROLISIS, DESCOMPOSICION CON ACIDO, REDUCCION, AMINOLISIS O HIDROGENOLISIS. ESTOS PEPTIDOS SON UTILES COMO MEDICINAS O AUXILIARES DE DIAGNOSTICO CLINICO PARA EL METABOLISMO DE LOS HUESOS Y EL SISTEMA NERVIOSO CENTRAL.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17534085 | 1985-08-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2000602A6 true ES2000602A6 (es) | 1988-03-01 |
Family
ID=15994349
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8600959A Expired ES2000602A6 (es) | 1985-08-09 | 1986-08-08 | Procedimiento para la preparacion de nuevos peptidos relacionados con la calcitonina |
Country Status (5)
Country | Link |
---|---|
US (1) | US4743677A (es) |
EP (1) | EP0212432B1 (es) |
JP (1) | JPS62129297A (es) |
DE (1) | DE3685167D1 (es) |
ES (1) | ES2000602A6 (es) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5049654A (en) * | 1986-12-04 | 1991-09-17 | Toyo Jozo Kabushiki Kaisha | Calcitonin gene related peptide derivatives |
JPS6426598A (en) * | 1987-07-22 | 1989-01-27 | Toyo Jozo Kk | Calcitonin gene related peptide derivative |
JPH02262595A (ja) * | 1988-02-29 | 1990-10-25 | Otsuka Pharmaceut Co Ltd | ポリペプチド誘導体 |
WO1990004605A1 (en) * | 1988-10-20 | 1990-05-03 | Celltech Limited | Calcitonin gene related peptide analogues |
DE3943519A1 (de) * | 1989-04-27 | 1991-01-17 | Stief Georg | Arzneimittel zur behandlung erektiler dysfunktionen |
GB8915712D0 (en) * | 1989-07-08 | 1989-08-31 | Macintyre Iain | Medical treatment |
DE69020722T2 (de) * | 1989-11-08 | 1996-01-18 | Daicel Chem | Peptide und verfahren zur herstellung von zyklischen peptiden. |
JPH06507602A (ja) * | 1991-02-12 | 1994-09-01 | ルミニス ピーティーワイ リミテッド | ペプチド |
HU222249B1 (hu) * | 1991-03-08 | 2003-05-28 | Amylin Pharmaceuticals Inc. | Eljárás amilin agonista peptidszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására |
WO1992015317A1 (en) * | 1991-03-08 | 1992-09-17 | Amylin Pharmaceuticals, Inc. | Synthetic preparation of amylin and amylin analogues |
WO1996029343A1 (fr) * | 1995-03-20 | 1996-09-26 | Kyowa Hakko Kogyo Co., Ltd. | Nouveaux derives de calcitonine |
US5962270A (en) * | 1996-02-06 | 1999-10-05 | Bionebraska, Inc. | Recombinant preparation of calcitonin fragments and use thereof in the preparation of calcitonin and related analogs |
WO1998001133A1 (fr) * | 1996-07-08 | 1998-01-15 | Yamanouchi Pharmaceutical Co., Ltd. | Inhibiteurs de la resorption osseuse |
WO2001068118A1 (en) * | 2000-03-14 | 2001-09-20 | National Jewish Medical And Research Center | Method for reducing allergen-induced airway hyperresponsiveness |
KR100418962B1 (ko) * | 2001-06-07 | 2004-02-14 | 김학주 | 2-(4-나이트로페닐설포닐)에톡시카르보닐-아미노산류를사용하여 펩티드를 고수율 및 고순도로 제조하는 방법 |
BRPI0618705B8 (pt) | 2005-11-14 | 2021-05-25 | Labrys Biologics Inc | anticorpos antagonistas humanizados direcionados contra peptídeo relacionado ao gene da calcitonina, composição farmacêutica e uso dos mesmos |
EP2265287B1 (en) | 2008-03-04 | 2018-09-05 | Teva Pharmaceuticals International GmbH | Methods of treating chronic pain |
EP2470207A1 (en) | 2009-08-28 | 2012-07-04 | Rinat Neuroscience Corporation | Methods for treating visceral pain by administering antagonist antibodies directed against calcitonin gene-related peptide |
EA033109B1 (ru) | 2011-05-20 | 2019-08-30 | Олдербайо Холдингз Ллк | Способы ингибирования, профилактики или лечения диареи и/или поддержания соответствующих уровней электролитов и жидкости в толстой кишке субъекта, подвергающегося связанному с диареей состоянию, с помощью антитела против cgrp или фрагмента антитела против cgrp |
EA201891284A1 (ru) | 2011-05-20 | 2018-11-30 | Олдербайо Холдингз Ллк | Композиции антител против cgrp и их применение |
CN108014334B (zh) | 2011-05-20 | 2021-11-30 | H.伦德贝克公司 | 抗cgrp抗体和抗体片段用于在有需要的受试者中预防或抑制畏光或厌光的用途 |
ES2641325T3 (es) | 2012-01-26 | 2017-11-08 | Christopher J. Soares | Antagonistas peptídicos de la familia calcitonina CGRP de hormonas peptídicas y su uso |
US10556945B2 (en) | 2014-03-21 | 2020-02-11 | Teva Pharmaceuticals International Gmbh | Antagonist antibodies directed against calcitonin gene-related peptide and methods using same |
JP6568099B2 (ja) | 2014-03-21 | 2019-08-28 | テバ・ファーマシューティカルズ・インターナショナル・ゲーエムベーハーTeva Pharmaceuticals International GmbH | カルシトニン遺伝子関連ペプチドに対するアンタゴニスト抗体及びその使用方法 |
IL265099B1 (en) | 2016-09-02 | 2024-05-01 | Christopher J Soares | Medicinal compositions containing an effective amount of a calcitonin gene-related peptide (CGRP) receptor antagonist, or a pharmaceutically acceptable salt thereof, for the treatment of glaucoma |
KR20220031944A (ko) | 2016-09-23 | 2022-03-14 | 테바 파마슈티컬스 인터내셔널 게엠베하 | 불응성 편두통의 치료 |
CN109406709B (zh) * | 2018-12-27 | 2020-11-10 | 福建省中医药研究院(福建省青草药开发服务中心) | 一种太子参药材中氨基酸类成分的薄层鉴别方法 |
JP2022516956A (ja) | 2019-01-08 | 2022-03-03 | ハー・ルンドベック・アクチエゼルスカベット | 抗cgrp抗体を用いた頭痛の急性治療及び迅速治療 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4514331A (en) * | 1983-06-29 | 1985-04-30 | University Patents, Inc. | Peptide hormones with calcitonin-like activity |
US4549986A (en) * | 1983-12-23 | 1985-10-29 | The Salk Institute For Biological Studies | Human CGRP |
-
1986
- 1986-07-23 JP JP61173395A patent/JPS62129297A/ja active Pending
- 1986-08-05 DE DE8686110829T patent/DE3685167D1/de not_active Expired - Lifetime
- 1986-08-05 US US06/893,267 patent/US4743677A/en not_active Expired - Fee Related
- 1986-08-05 EP EP86110829A patent/EP0212432B1/en not_active Expired - Lifetime
- 1986-08-08 ES ES8600959A patent/ES2000602A6/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
US4743677A (en) | 1988-05-10 |
JPS62129297A (ja) | 1987-06-11 |
EP0212432B1 (en) | 1992-05-06 |
EP0212432A3 (en) | 1989-01-25 |
DE3685167D1 (de) | 1992-06-11 |
EP0212432A2 (en) | 1987-03-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC1A | Transfer granted |
Owner name: ASAHI KASEI KABUSHIKI KAISHA |