ES2000602A6 - Procedimiento para la preparacion de nuevos peptidos relacionados con la calcitonina - Google Patents

Procedimiento para la preparacion de nuevos peptidos relacionados con la calcitonina

Info

Publication number
ES2000602A6
ES2000602A6 ES8600959A ES8600959A ES2000602A6 ES 2000602 A6 ES2000602 A6 ES 2000602A6 ES 8600959 A ES8600959 A ES 8600959A ES 8600959 A ES8600959 A ES 8600959A ES 2000602 A6 ES2000602 A6 ES 2000602A6
Authority
ES
Spain
Prior art keywords
related peptide
peptide derivatives
calcitonin gene
gene related
asn
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8600959A
Other languages
English (en)
Inventor
Toshiharj Noda
Nobutaka Fujii
Kaorj Morita
Masayuki Hori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Kasei Corp
Original Assignee
Toyo Jozo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyo Jozo KK filed Critical Toyo Jozo KK
Publication of ES2000602A6 publication Critical patent/ES2000602A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57527—Calcitonin gene related peptide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE NUEVOS PEPTIDOS RELACIONADOS CON LA CALCITONINA. COMPRENDE SOMETER A CONDENSACION, POR LA TECNICA DE LA FASE LIQUIDA Y/O DE LA FASE SOLIDA LOS CORRESPONDIENTES AMINOACIDOS O PEPTIDOS PARCIALES CONSTITUTIVOS DEL PEPTIDO, SEGUIDO DE ELIMINACION DE LOS GRUPOS PROTECTORES MEDIANTE HIDROLISIS, DESCOMPOSICION CON ACIDO, REDUCCION, AMINOLISIS O HIDROGENOLISIS. ESTOS PEPTIDOS SON UTILES COMO MEDICINAS O AUXILIARES DE DIAGNOSTICO CLINICO PARA EL METABOLISMO DE LOS HUESOS Y EL SISTEMA NERVIOSO CENTRAL.
ES8600959A 1985-08-09 1986-08-08 Procedimiento para la preparacion de nuevos peptidos relacionados con la calcitonina Expired ES2000602A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP17534085 1985-08-09

Publications (1)

Publication Number Publication Date
ES2000602A6 true ES2000602A6 (es) 1988-03-01

Family

ID=15994349

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8600959A Expired ES2000602A6 (es) 1985-08-09 1986-08-08 Procedimiento para la preparacion de nuevos peptidos relacionados con la calcitonina

Country Status (5)

Country Link
US (1) US4743677A (es)
EP (1) EP0212432B1 (es)
JP (1) JPS62129297A (es)
DE (1) DE3685167D1 (es)
ES (1) ES2000602A6 (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3782010T2 (de) * 1986-12-04 1993-02-18 Toyo Jozo Kk Vom calcitonin-gen abgeleitete peptidderivate.
JPS6426598A (en) * 1987-07-22 1989-01-27 Toyo Jozo Kk Calcitonin gene related peptide derivative
JPH02262595A (ja) * 1988-02-29 1990-10-25 Otsuka Pharmaceut Co Ltd ポリペプチド誘導体
EP0367463A1 (en) * 1988-10-20 1990-05-09 Celltech Limited Calcitonin gene related peptide analogues
DE3943519A1 (de) * 1989-04-27 1991-01-17 Stief Georg Arzneimittel zur behandlung erektiler dysfunktionen
GB8915712D0 (en) * 1989-07-08 1989-08-31 Macintyre Iain Medical treatment
DK0452514T3 (da) * 1989-11-08 1995-08-21 Daicel Chem Peptid og fremgangsmåde til fremstilling af cyclisk peptid
JPH06507602A (ja) * 1991-02-12 1994-09-01 ルミニス　ピーティーワイ　リミテッド ペプチド
HU222249B1 (hu) * 1991-03-08 2003-05-28 Amylin Pharmaceuticals Inc. Eljárás amilin agonista peptidszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására
WO1992015317A1 (en) * 1991-03-08 1992-09-17 Amylin Pharmaceuticals, Inc. Synthetic preparation of amylin and amylin analogues
WO1996029343A1 (en) * 1995-03-20 1996-09-26 Kyowa Hakko Kogyo Co., Ltd. Novel calcitonin derivatives
US5962270A (en) 1996-02-06 1999-10-05 Bionebraska, Inc. Recombinant preparation of calcitonin fragments and use thereof in the preparation of calcitonin and related analogs
AU3359697A (en) * 1996-07-08 1998-02-02 Yamanouchi Pharmaceutical Co., Ltd. Bone resorption inhibitors
EP1265626B1 (en) * 2000-03-14 2014-09-10 National Jewish Health Method for reducing allergen-induced airway hyperresponsiveness
KR100418962B1 (ko) * 2001-06-07 2004-02-14 김학주 2-(4-나이트로페닐설포닐)에톡시카르보닐-아미노산류를사용하여 펩티드를 고수율 및 고순도로 제조하는 방법
JP5123197B2 (ja) 2005-11-14 2013-01-16 ライナット ニューロサイエンス コーポレイション カルシトニン遺伝子関連ペプチドに対するアンタゴニスト抗体およびその使用方法
JP5537441B2 (ja) 2008-03-04 2014-07-02 ファイザー・リミテッド 慢性疼痛を治療する方法
KR101519192B1 (ko) 2009-08-28 2015-05-11 리나트 뉴로사이언스 코프. 칼시토닌 유전자-관련된 펩티드에 대해 지시된 길항제 항체의 투여에 의한 내장 통증의 치료 방법
EP3662932B1 (en) 2011-05-20 2021-04-07 H. Lundbeck A/S Anti-cgrp compositions and use thereof
NZ732970A (en) 2011-05-20 2022-08-26 H Lundbeck As Use of anti-cgrp antibodies and antibody fragments to prevent or inhibit photophobia or light aversion in subjects in need thereof, especially migraine sufferers
CN103957935B (zh) 2011-05-20 2018-04-03 奥尔德生物控股有限责任公司 抗cgrp或抗cgrp‑r抗体或抗体片段用于治疗或预防慢性和急性形式的腹泻的用途
MX347229B (es) * 2012-01-26 2017-04-19 Christopher J Soares Antagonistas de péptido de la familia cgrp de calcitonina de hormonas de péptido y su uso.
US20170114122A1 (en) 2015-10-23 2017-04-27 Alderbio Holdings Llc Regulation of glucose metabolism using anti-cgrp antibodies
HRP20240159T1 (hr) 2014-03-21 2024-04-12 Teva Pharmaceuticals International Gmbh Antagonistička protutijela usmjerena protiv peptida povezanog s genom kalcitonina i postupci koji ih koriste
US10556945B2 (en) 2014-03-21 2020-02-11 Teva Pharmaceuticals International Gmbh Antagonist antibodies directed against calcitonin gene-related peptide and methods using same
ES2965087T3 (es) 2016-09-02 2024-04-10 Soares Christopher J Uso de antagonistas de receptor de CGRP en el tratamiento de glaucoma
KR20220031944A (ko) 2016-09-23 2022-03-14 테바 파마슈티컬스 인터내셔널 게엠베하 불응성 편두통의 치료
CN109406709B (zh) * 2018-12-27 2020-11-10 福建省中医药研究院(福建省青草药开发服务中心） 一种太子参药材中氨基酸类成分的薄层鉴别方法
US11639380B2 (en) 2019-01-08 2023-05-02 H. Lundbeck A/S Acute treatment and rapid treatment of headache using anti-CGRP antibodies
CA3077973A1 (en) 2020-04-06 2021-10-06 H. Lundbeck A/S Treatment of most bothersome symptom (mbs) associated with migraine using anti-cgrp antibodies

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4514331A (en) * 1983-06-29 1985-04-30 University Patents, Inc. Peptide hormones with calcitonin-like activity
US4549986A (en) * 1983-12-23 1985-10-29 The Salk Institute For Biological Studies Human CGRP

Also Published As

Publication number Publication date
EP0212432A2 (en) 1987-03-04
US4743677A (en) 1988-05-10
JPS62129297A (ja) 1987-06-11
DE3685167D1 (de) 1992-06-11
EP0212432B1 (en) 1992-05-06
EP0212432A3 (en) 1989-01-25

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Legal Events

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Owner name: ASAHI KASEI KABUSHIKI KAISHA