ES2000181A6 - Procedimiento para la obtencion de derivados de indol - Google Patents

Procedimiento para la obtencion de derivados de indol

Info

Publication number
ES2000181A6
ES2000181A6 ES8600027A ES8600027A ES2000181A6 ES 2000181 A6 ES2000181 A6 ES 2000181A6 ES 8600027 A ES8600027 A ES 8600027A ES 8600027 A ES8600027 A ES 8600027A ES 2000181 A6 ES2000181 A6 ES 2000181A6
Authority
ES
Spain
Prior art keywords
alkyl
ch2ch2
indole derivatives
substituted
choh
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8600027A
Other languages
English (en)
Inventor
Henning Bottcher
Hans-Heinrich Hausberg
Christoph Seyfried
Klaus-Otto Mink
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of ES2000181A6 publication Critical patent/ES2000181A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE INDOL, DE FORMULA GENERAL I EN LA QUE LOS SUSTITUYENTES TIENEN LOS SIGNIFICADOS INDICADOS EN LA DESCRIPCION, QUE COMPRENDE HACER REACCIONAR UN COMPUESTO DE FORMULA GENERAL II CON UN COMPUESTO DE FORMULA GENERAL III
ES8600027A 1985-06-27 1986-06-27 Procedimiento para la obtencion de derivados de indol Expired ES2000181A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853522959 DE3522959A1 (de) 1985-06-27 1985-06-27 Indolderivate

Publications (1)

Publication Number Publication Date
ES2000181A6 true ES2000181A6 (es) 1988-01-01

Family

ID=6274313

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8600027A Expired ES2000181A6 (es) 1985-06-27 1986-06-27 Procedimiento para la obtencion de derivados de indol

Country Status (8)

Country Link
US (2) US4740602A (es)
EP (1) EP0206225A3 (es)
JP (1) JPS624285A (es)
AU (1) AU592578B2 (es)
DE (1) DE3522959A1 (es)
ES (1) ES2000181A6 (es)
HU (1) HU196786B (es)
ZA (1) ZA864770B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2619112B1 (fr) * 1987-08-07 1989-11-17 Synthelabo Derives de (piperidinyl-4)methyl-2 benzo(b)furo(2,3-c) pyridines, leur preparation et leur application en therapeutique
US5049564A (en) * 1989-11-17 1991-09-17 Abbott Laboratories 5-HT selective agents
JPH03502701A (ja) * 1988-12-15 1991-06-20 アボツト・ラボラトリーズ ５‐ｈｔ選択性物質
GR1001059B (el) * 1988-12-15 1993-04-28 Abbott Lab Μεθοδος παραγωγης εκλεκτικων παραγοντων 5-ητ.
US5294618A (en) * 1989-07-28 1994-03-15 Merck Sharp & Dohme Limited Octahydrobenzisoquinoline derivatives as antipsychotic agents
US5244888A (en) * 1989-11-17 1993-09-14 Abbott Laboratories 5-HT selective agents
GB9014061D0 (en) * 1990-06-25 1990-08-15 Merck Sharp & Dohme Therapeutic agents
US5288743A (en) * 1992-11-20 1994-02-22 Abbott Laboratories Indole carboxylate derivatives which inhibit leukotriene biosynthesis
US5688950A (en) * 1996-04-23 1997-11-18 Neurogen Corporation Tricyclic aminoalkylcarboxamides; novel dopamine D3 receptor subtype specific ligands
WO1998027984A1 (en) * 1996-12-20 1998-07-02 Neurex Corporation METHOD OF PRODUCING ANALGESIA BY ADMINISTRATION OF 1,2,3,4-TETRAHYDROBENZO-[b]THIENO[2,3-c]PYRIDINE AND DERIVATIVES
NZ510116A (en) * 1998-10-06 2002-10-25 Janssen Pharmaceutica Nv Tricyclic delta-3-piperidines as pharmaceuticals
UA69420C2 (uk) 1998-10-06 2004-09-15 Янссен Фармацевтика Н.В. ТРИЦИКЛІЧНІ <font face="Symbol">D3</font>-ПІПЕРИДИНИ ЯК <font face="Symbol">a<sub></font>2</sub>-АНТАГОНІСТИ
EE200100329A (et) * 1998-12-21 2002-08-15 Janssen Pharmaceutica N.V. Bensisoksasoolid ja fenoonid, nende valmistamismeetod ja kasutamine ning kompositsioon ja selle valmistamismeetod
US8546377B2 (en) 2009-04-23 2013-10-01 Abbvie Inc. Modulators of 5-HT receptors and methods of use thereof
ES2568262T3 (es) * 2009-04-23 2016-04-28 Abbvie Inc. Moduladores de receptores de 5-HT y sus métodos de uso
US8518933B2 (en) * 2009-04-23 2013-08-27 Abbvie Inc. Modulators of 5-HT receptors and methods of use thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3767659A (en) * 1968-03-05 1973-10-23 Colgate Palmolive Co Derivatives of 3,4-dihydrobenzothieno(2,3-c)pyridine
DE2624967A1 (de) * 1975-06-13 1976-12-23 Sandoz Ag Neue organische verbindungen, ihre herstellung und verwendung
DE2640022A1 (de) * 1975-09-15 1977-03-24 Sandoz Ag Neue organische verbindungen, ihre herstellung und verwendung
FR2334351A1 (fr) * 1975-12-12 1977-07-08 Warner Lambert Co 3-thiomethyl-2(2-(dialcoylamino)ethyl) indoles, leur procede de preparation et leur application
FR2400518A1 (fr) * 1977-08-18 1979-03-16 Parcor Benzo(b)thieno(3,2-c) et (2,3-c)pyridines, leur procede de preparation et leur application en therapeutique
FR2414048A1 (fr) * 1978-01-04 1979-08-03 Parcor Benzofuro (2,3-c) pyridines, leur procede de preparation et leur application en therapeutique
DE3342632A1 (de) * 1983-11-25 1985-06-05 Merck Patent Gmbh, 6100 Darmstadt Indolderivate

Also Published As

Publication number Publication date
JPS624285A (ja) 1987-01-10
AU592578B2 (en) 1990-01-18
HU196786B (en) 1989-01-30
US4824852A (en) 1989-04-25
EP0206225A3 (de) 1987-09-23
AU5917586A (en) 1987-01-08
ZA864770B (en) 1987-02-25
EP0206225A2 (de) 1986-12-30
US4740602A (en) 1988-04-26
HUT44780A (en) 1988-04-28
DE3522959A1 (de) 1987-01-08

Similar Documents

Publication Publication Date Title
ES2000181A6 (es) Procedimiento para la obtencion de derivados de indol
BR8004900A (pt) Copolimeros hidrossoluveis,sua preparacao e emprego
IL97538A0 (en) Liposomes containing an aminoglycoside salt and their preparation
IT8447918A0 (it) Sistema per ridurre la dispersione dei colpi sparati da un sistema d&#39;arma
ZA837311B (en) Sulfur-containing indole derivatives
ES8605814A1 (es) Procedimiento para la obtencion de nuevas ureas n-glico-si- ladas,carbamatos y tiocarbamatos
ES8504786A1 (es) Procedimiento para la obtencion de derivados de indol
ES477785A1 (es) Procedimiento para la preparacion de nuevas 2-fenilimino- imidazolidinas sustituidas.
ES8502108A1 (es) Procedimiento para la obtencion de derivados de tetrahidrocarbazol
ES8609344A1 (es) Cefalosporinas
DE3268541D1 (en) Benzodioxane-imidazoline compounds, their preparation and use
ATE34983T1 (de) Indolderivate.
JPS579782A (en) Novel compound
ES2000281A6 (es) Procedimiento para la obtencion de 6-arialquenilpiradizinonas
IT8420823A1 (it) &#34;Cristallino artificiale dell&#39;occhio&#34;
IT8419813V0 (it) Cavigliera-polsino per potenziamento muscolare a mezzo di attivita&#39;per tutte le attivita&#39; sportive
JPS52128348A (en) Alpha-chlorocarboxylic acid derivatives and their preparation
IT1207700B (it) Apparecchiatura per la valutazione dinamonetrica dell&#39;efficienza muscolare
PL273024A1 (en) Method of obtaining substituted 9h-indolo /1,2-f/phenanthydrinic salts
JPS5285186A (en) 6-aminopenicillanic acid derivatives
CS424688A2 (en) Method of cephalosporin&#39;s new salts production

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20100623