ES2000168A4 - Aparato para la filtracion continua de cultivos de celulas. - Google Patents

Aparato para la filtracion continua de cultivos de celulas.

Info

Publication number
ES2000168A4
ES2000168A4 ES87870014T ES87870014T ES2000168A4 ES 2000168 A4 ES2000168 A4 ES 2000168A4 ES 87870014 T ES87870014 T ES 87870014T ES 87870014 T ES87870014 T ES 87870014T ES 2000168 A4 ES2000168 A4 ES 2000168A4
Authority
ES
Spain
Prior art keywords
filter unit
shaft
pair
vessel
vanes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES87870014T
Other languages
English (en)
Other versions
ES2000168T3 (es
Inventor
William Robert Tolbert
Raymond Charles Geimer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Monsanto Co
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Publication of ES2000168A4 publication Critical patent/ES2000168A4/es
Application granted granted Critical
Publication of ES2000168T3 publication Critical patent/ES2000168T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02—Stirrer or mobile mixing elements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/16—Particles; Beads; Granular material; Encapsulation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

UN APARATO PARA LA FILTRACION CONTINUA DE CELULAS ADAPTADO PARA SU MONTAJE Y DESMONTAJE MANUALES QUE INCLUYE: (A) UN RECIPIENTE HUECO (10) QUE TIENE UNA ABERTURA (13) EN LA PARTE SUPERIOR. (B) UN EJE HUECO ESTACIONARIO (26) SITUADO DENTRO DEL RECIPIENTE (10) EN COMUNICACION CON LA ABERTURA (13) DE DICHO RECIPIENTE (10) Y SOPORTADO HACIA ABAJO SIN COJINETE INFERIOR. (C) UNA UNIDAD DE FILTRO ESTACIONARIA (35) SOPORTADA HACIA ABAJO DESDE EL EJE (26) SIN COJINETE INFERIOR Y SIN CIERRES MOVILES ENTRE LA UNIDAD DE FILTRO NI NINGUN MEDIO DE APOYO MOVIL DEL FILTRO QUE PUDIERA ESTAR EN CONTACTO CON LA SUSPENSION DE CELULAS. DICHO FILTRO TIENE: (1) UNA CAVIDAD DE RECOGIDA DE FLUIDO EN COMUNICACION DIRECTA CON EL INTERIOR DEL EJE (26) Y LA PARTE SUPERIOR DEL RECIPIENTE, Y (2) UNA SUPERFICIE EXTERIOR POROSA QUE TIENE UN TAMAÑO DE POROS MENOR QUE EL DE LAS CELULAS A CULTIVAR O DE LAS PARTICULAS DEL PORTADOR AL QUE ESTAN UNIDAS LAS CELULAS, PERO SUFICIENTEMENTE GRANDE PARA PERMITIR LA PENETRACION DELFLUIDO AL INTERIOR DE LA CAVIDAD DE RECOGIDA. (D) UN DISPOSITIVO AGITADOR ROTATIVO (25) SOPORTADO HACIA ABAJO DESDE EL EJE (26) Y DISPUESTO CONCENTRICAMENTE CON LA UNIDAD DE FILTRO (35) PARA GIRAR POR SUSPENSION DE LOS APOYOS (39), (40) QUE TIENEN UN MONTAJE DE BAJO ROZAMIENTO CON EL EJE HUECO (26). (E) EL EJE (26) TIENE UN SALIENTE (77) SITUADO ENTRE LA UNIDAD DE FILTRO (35) Y LOS APOYOS (39), (40) Y UN ASIENTO DE MUELLE (76) ADAPTABLE PARA SOSTENER UN MUELLE (75) SITUADO ENTRE EL SALIENTE (77) Y LA UNIDAD DE FILTRO. (F) EL DISPOSITIVO AGITADOR (25) TIENE SUSPENDIDAS VARIAS PALETAS FLEXIBLES (30) QUE ESTAN REGULARMENTE SEPARADAS A LO LARGO DE LA CIRCUNFERENCIA Y QUE SE PROLONGAN POR TODA LA LONGITUD DE LA UNIDAD DE FILTRO (35), ESTANDO SOSTENIDAS ENTRE UN PAR DE PLACAS DE FIJACION SUPERIORES (51,61) Y UN PAR DE PLACAS DE FIJACION INFERIORES (52,62) TENIENDO LA PIEZA INFERIOR (51) DEL PAR SUPERIOR Y LA PIEZA SUPERIOR (52) DEL PAR INFERIOR DE PLACAS DE FIJACION RANURAS LATERALES ESPACIADAS A LO LARGO DE LA CIRCUNFERENCIA PARA RECIBIR LA PARTE ANCHA DE LAS PALETAS (30) TENIENDO ESTAS, PIEZAS DE UN ELASTOMERO EN CADA EXTREMO COMPRIMIDAS ENTRE EL CORRESPONDIENTE PAR DE PLACAS.
ES87870014T 1986-02-03 1987-02-02 Aparato para la filtracion continua de cultivos de celulas. Expired - Lifetime ES2000168T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/825,717 US4639422A (en) 1986-02-03 1986-02-03 Cell culture filter apparatus and method

Publications (2)

Publication Number Publication Date
ES2000168A4 true ES2000168A4 (es) 1988-01-01
ES2000168T3 ES2000168T3 (es) 1994-01-16

Family

ID=25244747

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87870014T Expired - Lifetime ES2000168T3 (es) 1986-02-03 1987-02-02 Aparato para la filtracion continua de cultivos de celulas.

Country Status (8)

Country Link
US (1) US4639422A (es)
EP (1) EP0233168B1 (es)
JP (1) JPH0817691B2 (es)
AT (1) ATE95229T1 (es)
AU (1) AU599074B2 (es)
CA (1) CA1267623C (es)
DE (1) DE3787539T2 (es)
ES (1) ES2000168T3 (es)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5605835A (en) * 1988-05-23 1997-02-25 Regents Of The University Of Minnesota Bioreactor device with application as a bioartificial liver
US5002890A (en) * 1988-11-29 1991-03-26 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Spiral vane bioreactor
US5019512A (en) * 1989-03-17 1991-05-28 Baxter International Inc. Spin filter for removing substantially cell-free culture medium from suspension cell culture system
US5126269A (en) * 1990-09-13 1992-06-30 Life Techologies, Inc. Spin filter perfusion bioreactor (sfpb) cell culture apparatus
US5792603A (en) * 1995-04-27 1998-08-11 Advanced Tissue Sciences, Inc. Apparatus and method for sterilizing, seeding, culturing, storing, shipping and testing tissue, synthetic or native, vascular grafts
US5846828A (en) * 1995-06-07 1998-12-08 Advanced Tissue Sciences Apparatus and method for sterilizing, seeding, culturing, storing, shipping, and testing tissue, synthetic, or mechanical heart valves orvalve segments
US6121042A (en) * 1995-04-27 2000-09-19 Advanced Tissue Sciences, Inc. Apparatus and method for simulating in vivo conditions while seeding and culturing three-dimensional tissue constructs
AU5931896A (en) * 1995-06-07 1996-12-30 Advanced Tissue Sciences, Inc. Apparatus and method for sterilizing, seeding, culturing, st oring, shipping, and testing replacement cartilage tissue co nstructs
US5843766A (en) * 1995-06-07 1998-12-01 Advanced Tissue Sciences, Inc. Apparatus for the growth and packaging of three dimensional tissue cultures
US5763267A (en) * 1996-04-16 1998-06-09 Advanced Tissue Sciences Apparatus for the large scale growth and packaging of cell suspensions and three-dimensional tissue cultures
US6794184B1 (en) * 1998-01-19 2004-09-21 Ulrich Mohr Culturing device and method for culturing cells or tissue components
US6367406B1 (en) * 1999-09-24 2002-04-09 Larson/Glastron Boats, Inc. Boat and method for manufacturing using resin transfer molding
DE10003896A1 (de) 2000-01-29 2001-08-02 Zahnradfabrik Friedrichshafen Verfahren zur Steuerung eines Proportional-Magneten mit Haltefunktion
US7160719B2 (en) 2002-06-07 2007-01-09 Mayo Foundation For Medical Education And Research Bioartificial liver system
US20040029266A1 (en) * 2002-08-09 2004-02-12 Emilio Barbera-Guillem Cell and tissue culture device
US7514256B2 (en) * 2005-02-11 2009-04-07 Emilio Barbera-Guillem Bioreactor for selectively controlling the molecular diffusion between fluids
KR100932861B1 (ko) * 2007-11-30 2009-12-21 코아스템(주) 세포배양플라스크
KR100946643B1 (ko) * 2007-11-30 2010-03-09 코아스템(주) 세포배양장치 및 이를 구비한 대용량 자동화 세포배양기
EP2405957B1 (en) 2009-03-13 2020-12-23 Mayo Foundation For Medical Education And Research Bioartificial liver
US9622421B2 (en) 2010-02-19 2017-04-18 Glen Babcock Carbon dioxide supplementation product with delayed activation control
US9750196B2 (en) 2010-02-19 2017-09-05 Glen Babcock Mycelial mass with non-electrical carbon dioxide transfer
US10512223B2 (en) 2010-02-19 2019-12-24 Glen Babcock Multi-compartment carbon dioxide supplementation device with delayed activation control
US8690752B2 (en) 2012-08-03 2014-04-08 Alison Jane Jose Oocyte separation and collection system
KR101881238B1 (ko) * 2014-02-17 2018-07-23 아사히 가세이 가부시키가이샤 세포 배양 장치
JP6296446B2 (ja) * 2014-02-26 2018-03-20 シャープ株式会社 発酵装置
EP3207119B1 (en) * 2014-10-17 2020-02-19 Sani-tech West, Inc. Mixing and filtering system
CN104932203A (zh) * 2015-07-10 2015-09-23 深圳市华星光电技术有限公司 一种光阻汲取装置
EP3199616B1 (de) * 2016-01-29 2024-08-21 Eppendorf SE Einweg-anschlusseinrichtung
US11788048B2 (en) * 2017-09-19 2023-10-17 Life Technologies Corporation Systems and methods for a collapsible chamber with foldable mixing element
US20200277560A1 (en) * 2017-11-29 2020-09-03 Corning Incorporated Filtered cell culture caps and cell culture methods
WO2019148022A1 (en) * 2018-01-26 2019-08-01 Martin Nathaniel J Water movement system and method for controlling water breeding insect populations
CN113018928A (zh) * 2021-04-21 2021-06-25 周向前 流体中颗粒捕集装置及流体中颗粒捕集方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3039932A (en) * 1958-01-07 1962-06-19 Research Corp Tissue culturing with arginine, citrulline or aspartic acids supplements to the media
US2958517A (en) * 1958-04-28 1960-11-01 Bellco Glass Inc Vessel for tissue culture and the like comprising a magnetic stirrer
US4178209A (en) * 1977-11-14 1979-12-11 Monsanto Company Continuous cell culture method and apparatus
US4166768A (en) * 1977-11-14 1979-09-04 Monsanto Company Continuous cell culture system
US4184916A (en) * 1977-11-14 1980-01-22 Monsanto Company Continuous cell culture system
US4289854A (en) * 1980-06-20 1981-09-15 Monsanto Company Cell culture method and apparatus

Also Published As

Publication number Publication date
JPS62210980A (ja) 1987-09-17
ATE95229T1 (de) 1993-10-15
ES2000168T3 (es) 1994-01-16
JPH0817691B2 (ja) 1996-02-28
CA1267623A (en) 1990-04-10
DE3787539T2 (de) 1994-04-28
EP0233168A2 (en) 1987-08-19
AU6821587A (en) 1987-08-06
DE3787539D1 (de) 1993-11-04
AU599074B2 (en) 1990-07-12
US4639422A (en) 1987-01-27
EP0233168B1 (en) 1993-09-29
CA1267623C (en) 1990-04-10
EP0233168A3 (en) 1988-09-14

Similar Documents

Publication Publication Date Title
ES2000168T3 (es) Aparato para la filtracion continua de cultivos de celulas.
DK0495213T3 (da) Cellekultur-indsats
US4377639A (en) Tissue culture device for mass cell culture
US3448011A (en) Sterile filter
DE2964597D1 (en) Filtration apparatus for separating blood cell-containing liquid suspensions
CA2278630A1 (en) Filtration assembly
DK0414887T3 (da) Spinnefilter til fjernelse af i det væsentlige cellefrit dyrningsmedium fra suspensionscelledyrkningssystem
FR2629091B1 (fr) Procede de production de membranes poreuses, membranes poreuses obtenues par ce procede et leur utilisation comme matrices de support dans des bandelettes reactives
AU550074B2 (en) Filter apparatus and method
GB1423218A (en) Apparatus for cultivating cellular tissues and microorganisms on rotatable substrates
DE3476737D1 (en) A device in the shape of a mobile business for public amusement
DE69820122D1 (de) Apparat zur suspension von kultivierten zellen aus gewebe und mikroorganismen
DE3380442D1 (en) Filler-containing polymer particles useful as carriers for supporting a biological substance
US2985587A (en) Method of and apparatus for dialysis
FI67490B (fi) Filtreringsenhet
CN214064468U (zh) 一种用于环境检测设备的安装支架
JPS6414389A (en) Screen apparatus for transferring cellulose fiber from one suspension stream to other suspension stream under high pressure atmosphere
CN213771539U (zh) 一种便于更换过滤布的过滤装置
CN215538830U (zh) 一种化学分析检验用过滤装置
CN215209367U (zh) 一种测序仪用孔板安装结构
FI894644A (fi) Urvattnare.
GB1465291A (en) Immersion percolating filter
JPS56159772A (en) Document selector
CN116328410A (zh) 过滤组件
DK585778A (da) Cellearrangement med flere plastiv-celler til filtre med graunuleret filtermaterilae

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 233168

Country of ref document: ES