GB1423218A - Apparatus for cultivating cellular tissues and microorganisms on rotatable substrates - Google Patents

Apparatus for cultivating cellular tissues and microorganisms on rotatable substrates

Info

Publication number
GB1423218A
GB1423218A GB3880473A GB3880473A GB1423218A GB 1423218 A GB1423218 A GB 1423218A GB 3880473 A GB3880473 A GB 3880473A GB 3880473 A GB3880473 A GB 3880473A GB 1423218 A GB1423218 A GB 1423218A
Authority
GB
United Kingdom
Prior art keywords
container
members
organisms
liquid nutrient
cultivating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3880473A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of GB1423218A publication Critical patent/GB1423218A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/06—Plates; Walls; Drawers; Multilayer plates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/14—Rotation or movement of the cells support, e.g. rotated hollow fibers

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

1423218 Apparatus for cultivating organisms H MULLER 16 Aug 1973 [18 Aug 1972] 38804/73 Heading B1C Apparatus for cultivating cellular tissues or micro-organisms on surfaces which are mounted for rotation in a container comprises a plurality of arcuate or radially extending members 1 secured along one side edge parallel to the axis of the rotary member 4 on which they are mounted the members being detachable. The members 1 forming a series of arcuate or radial pockets 2 and are rotated by way of a belt drive 16 and motor 13 within a glass cylindrical container 9. In operation the liquid nutrient is fed through connection 8 in the end wall 11 of the container and the container is filled to a level which just covers the rotatable member 4. Air is supplied or removed via the connections 6 in the upper portion of the container whereby cultivation of the organisms is effected by slow rotation of the rotary assembly 1 and 9 to expose the organisms to both liquid nutrient and air as the assembly rotates. The liquid nutrient drains into the lower portion of the container through holes 3 in the end support members 19 as the members rise into the upper half of the container.
GB3880473A 1972-08-18 1973-08-16 Apparatus for cultivating cellular tissues and microorganisms on rotatable substrates Expired GB1423218A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1232672A CH563456A5 (en) 1972-08-18 1972-08-18

Publications (1)

Publication Number Publication Date
GB1423218A true GB1423218A (en) 1976-02-04

Family

ID=4381972

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3880473A Expired GB1423218A (en) 1972-08-18 1973-08-16 Apparatus for cultivating cellular tissues and microorganisms on rotatable substrates

Country Status (6)

Country Link
US (1) US3925165A (en)
CH (1) CH563456A5 (en)
DD (1) DD107484A5 (en)
FR (1) FR2196388B1 (en)
GB (1) GB1423218A (en)
IT (1) IT998367B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007003742A1 (en) * 2007-01-19 2008-07-24 Schmack Biogas Ag Agitator for fermenter for production of biogases, comprises horizontally arranged agitator shaft for breaking fermenter wall, which has agitator shaft bearing supported on fermenter wall
CN111518693A (en) * 2020-04-30 2020-08-11 王家文 Rotary radial spreading axial multi-sheet adherent cell culture device

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH635868A5 (en) * 1977-08-16 1983-04-29 Chemap Ag DEVICE FOR TISSUE TISSUE CELLS.
JPS5564795A (en) * 1978-11-10 1980-05-15 Olympus Optical Co Ltd Method and apparatus for culturing living tissue or cell
US4376826A (en) * 1980-06-17 1983-03-15 Mynatt Roy L Continuous production of bacteria for leaching of metallic ore
CH651586A5 (en) * 1981-04-27 1985-09-30 Inst Biokhim I Fiziol Mikroorg APPARATUS FOR BREEDING MICRO-ORGANISMS ON LIQUID GROWTH FLOORS.
CH647547A5 (en) * 1982-02-12 1985-01-31 Chemap Ag METHOD AND DEVICE FOR BREEDING MICROORGANISMS.
DE3544382A1 (en) * 1985-12-14 1987-06-19 Ivan Prof Dr Ing Sekoulov METHOD FOR THE OXYGEN SUPPLY OF BIOREACTORS AND DEVICE FOR IMPLEMENTING THE METHOD AND USE OF THE DEVICE
US5081035A (en) * 1988-04-18 1992-01-14 The University Of Michigan Bioreactor system
US5026650A (en) * 1988-06-30 1991-06-25 The United States Of Amercia As Represented By The Administrator Of The National Aeronautics And Space Administration Horizontally rotated cell culture system with a coaxial tubular oxygenator
US5650325A (en) * 1990-11-29 1997-07-22 Spielmann; Richard Apparatus having a rotatable stack of parallel trays with culturing surfaces on opposite sides for liquid/gas exchange
BE1004610A5 (en) * 1990-11-29 1992-12-22 Spielmann Richard BIOREACTOR ROTARY LARGE AREA FOR CELL CULTURE adherent OR SUSPENDED.
US5316945A (en) * 1991-12-14 1994-05-31 Will Minuth Cell carrier arrangement
US5427948A (en) * 1993-07-29 1995-06-27 Michigan State University Apparatus for conducting hybridization
JPH0768239A (en) * 1993-09-01 1995-03-14 Maashiyaru Plant Kk High speed fermentation processing machine
US5403742A (en) * 1993-09-01 1995-04-04 Ramot University Authority Ltd. Bioreactor for production of products with immobilized biofilm
US5437998A (en) * 1993-09-09 1995-08-01 Synthecon, Inc. Gas permeable bioreactor and method of use
US6001642A (en) * 1998-06-29 1999-12-14 Wyle Laboratories, Inc. Life Sciences Bioreactor and cell culturing processes using the bioreactor
US7086778B2 (en) * 2000-10-09 2006-08-08 Levtech, Inc. System using a levitating, rotating pumping or mixing element and related methods
US7198940B2 (en) 2000-10-25 2007-04-03 Shot Hardware Optimization Technology, Inc. Bioreactor apparatus and cell culturing system
KR20080074896A (en) * 2005-10-26 2008-08-13 레브테크 인크. Bloreactor with mlxer and sparger
EP2018416B1 (en) * 2006-05-13 2018-10-24 Pall Life Sciences Belgium Disposable bioreactor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2996429A (en) * 1959-02-12 1961-08-15 Nat Toxicological Lab Inc Method and apparatus for growing living tissue
US3767535A (en) * 1971-06-14 1973-10-23 Corning Glass Works Method of reacting an insolubilized enzyme in a fluid medium
US3839155A (en) * 1972-07-27 1974-10-01 Merck & Co Inc Cell and vaccine production

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007003742A1 (en) * 2007-01-19 2008-07-24 Schmack Biogas Ag Agitator for fermenter for production of biogases, comprises horizontally arranged agitator shaft for breaking fermenter wall, which has agitator shaft bearing supported on fermenter wall
CN111518693A (en) * 2020-04-30 2020-08-11 王家文 Rotary radial spreading axial multi-sheet adherent cell culture device

Also Published As

Publication number Publication date
DE2341180A1 (en) 1974-03-28
DD107484A5 (en) 1974-08-05
IT998367B (en) 1976-01-20
DE2341180B2 (en) 1975-09-25
US3925165A (en) 1975-12-09
CH563456A5 (en) 1975-06-30
FR2196388A1 (en) 1974-03-15
FR2196388B1 (en) 1977-08-12

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee