GB1423218A - Apparatus for cultivating cellular tissues and microorganisms on rotatable substrates - Google Patents
Apparatus for cultivating cellular tissues and microorganisms on rotatable substratesInfo
- Publication number
- GB1423218A GB1423218A GB3880473A GB3880473A GB1423218A GB 1423218 A GB1423218 A GB 1423218A GB 3880473 A GB3880473 A GB 3880473A GB 3880473 A GB3880473 A GB 3880473A GB 1423218 A GB1423218 A GB 1423218A
- Authority
- GB
- United Kingdom
- Prior art keywords
- container
- members
- organisms
- liquid nutrient
- cultivating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
- C12M25/06—Plates; Walls; Drawers; Multilayer plates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/14—Rotation or movement of the cells support, e.g. rotated hollow fibers
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
1423218 Apparatus for cultivating organisms H MULLER 16 Aug 1973 [18 Aug 1972] 38804/73 Heading B1C Apparatus for cultivating cellular tissues or micro-organisms on surfaces which are mounted for rotation in a container comprises a plurality of arcuate or radially extending members 1 secured along one side edge parallel to the axis of the rotary member 4 on which they are mounted the members being detachable. The members 1 forming a series of arcuate or radial pockets 2 and are rotated by way of a belt drive 16 and motor 13 within a glass cylindrical container 9. In operation the liquid nutrient is fed through connection 8 in the end wall 11 of the container and the container is filled to a level which just covers the rotatable member 4. Air is supplied or removed via the connections 6 in the upper portion of the container whereby cultivation of the organisms is effected by slow rotation of the rotary assembly 1 and 9 to expose the organisms to both liquid nutrient and air as the assembly rotates. The liquid nutrient drains into the lower portion of the container through holes 3 in the end support members 19 as the members rise into the upper half of the container.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH1232672A CH563456A5 (en) | 1972-08-18 | 1972-08-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1423218A true GB1423218A (en) | 1976-02-04 |
Family
ID=4381972
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB3880473A Expired GB1423218A (en) | 1972-08-18 | 1973-08-16 | Apparatus for cultivating cellular tissues and microorganisms on rotatable substrates |
Country Status (6)
Country | Link |
---|---|
US (1) | US3925165A (en) |
CH (1) | CH563456A5 (en) |
DD (1) | DD107484A5 (en) |
FR (1) | FR2196388B1 (en) |
GB (1) | GB1423218A (en) |
IT (1) | IT998367B (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102007003742A1 (en) * | 2007-01-19 | 2008-07-24 | Schmack Biogas Ag | Agitator for fermenter for production of biogases, comprises horizontally arranged agitator shaft for breaking fermenter wall, which has agitator shaft bearing supported on fermenter wall |
CN111518693A (en) * | 2020-04-30 | 2020-08-11 | 王家文 | Rotary radial spreading axial multi-sheet adherent cell culture device |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH635868A5 (en) * | 1977-08-16 | 1983-04-29 | Chemap Ag | DEVICE FOR TISSUE TISSUE CELLS. |
JPS5564795A (en) * | 1978-11-10 | 1980-05-15 | Olympus Optical Co Ltd | Method and apparatus for culturing living tissue or cell |
US4376826A (en) * | 1980-06-17 | 1983-03-15 | Mynatt Roy L | Continuous production of bacteria for leaching of metallic ore |
CH651586A5 (en) * | 1981-04-27 | 1985-09-30 | Inst Biokhim I Fiziol Mikroorg | APPARATUS FOR BREEDING MICRO-ORGANISMS ON LIQUID GROWTH FLOORS. |
CH647547A5 (en) * | 1982-02-12 | 1985-01-31 | Chemap Ag | METHOD AND DEVICE FOR BREEDING MICROORGANISMS. |
DE3544382A1 (en) * | 1985-12-14 | 1987-06-19 | Ivan Prof Dr Ing Sekoulov | METHOD FOR THE OXYGEN SUPPLY OF BIOREACTORS AND DEVICE FOR IMPLEMENTING THE METHOD AND USE OF THE DEVICE |
US5081035A (en) * | 1988-04-18 | 1992-01-14 | The University Of Michigan | Bioreactor system |
US5026650A (en) * | 1988-06-30 | 1991-06-25 | The United States Of Amercia As Represented By The Administrator Of The National Aeronautics And Space Administration | Horizontally rotated cell culture system with a coaxial tubular oxygenator |
US5650325A (en) * | 1990-11-29 | 1997-07-22 | Spielmann; Richard | Apparatus having a rotatable stack of parallel trays with culturing surfaces on opposite sides for liquid/gas exchange |
BE1004610A5 (en) * | 1990-11-29 | 1992-12-22 | Spielmann Richard | BIOREACTOR ROTARY LARGE AREA FOR CELL CULTURE adherent OR SUSPENDED. |
US5316945A (en) * | 1991-12-14 | 1994-05-31 | Will Minuth | Cell carrier arrangement |
US5427948A (en) * | 1993-07-29 | 1995-06-27 | Michigan State University | Apparatus for conducting hybridization |
JPH0768239A (en) * | 1993-09-01 | 1995-03-14 | Maashiyaru Plant Kk | High speed fermentation processing machine |
US5403742A (en) * | 1993-09-01 | 1995-04-04 | Ramot University Authority Ltd. | Bioreactor for production of products with immobilized biofilm |
US5437998A (en) * | 1993-09-09 | 1995-08-01 | Synthecon, Inc. | Gas permeable bioreactor and method of use |
US6001642A (en) * | 1998-06-29 | 1999-12-14 | Wyle Laboratories, Inc. Life Sciences | Bioreactor and cell culturing processes using the bioreactor |
US7086778B2 (en) * | 2000-10-09 | 2006-08-08 | Levtech, Inc. | System using a levitating, rotating pumping or mixing element and related methods |
US7198940B2 (en) | 2000-10-25 | 2007-04-03 | Shot Hardware Optimization Technology, Inc. | Bioreactor apparatus and cell culturing system |
KR20080074896A (en) * | 2005-10-26 | 2008-08-13 | 레브테크 인크. | Bloreactor with mlxer and sparger |
EP2018416B1 (en) * | 2006-05-13 | 2018-10-24 | Pall Life Sciences Belgium | Disposable bioreactor |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2996429A (en) * | 1959-02-12 | 1961-08-15 | Nat Toxicological Lab Inc | Method and apparatus for growing living tissue |
US3767535A (en) * | 1971-06-14 | 1973-10-23 | Corning Glass Works | Method of reacting an insolubilized enzyme in a fluid medium |
US3839155A (en) * | 1972-07-27 | 1974-10-01 | Merck & Co Inc | Cell and vaccine production |
-
1972
- 1972-08-18 CH CH1232672A patent/CH563456A5/xx not_active IP Right Cessation
-
1973
- 1973-08-09 FR FR7329798A patent/FR2196388B1/fr not_active Expired
- 1973-08-13 US US388036A patent/US3925165A/en not_active Expired - Lifetime
- 1973-08-14 IT IT27877/73A patent/IT998367B/en active
- 1973-08-16 GB GB3880473A patent/GB1423218A/en not_active Expired
- 1973-08-20 DD DD173055A patent/DD107484A5/xx unknown
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102007003742A1 (en) * | 2007-01-19 | 2008-07-24 | Schmack Biogas Ag | Agitator for fermenter for production of biogases, comprises horizontally arranged agitator shaft for breaking fermenter wall, which has agitator shaft bearing supported on fermenter wall |
CN111518693A (en) * | 2020-04-30 | 2020-08-11 | 王家文 | Rotary radial spreading axial multi-sheet adherent cell culture device |
Also Published As
Publication number | Publication date |
---|---|
DE2341180A1 (en) | 1974-03-28 |
DD107484A5 (en) | 1974-08-05 |
IT998367B (en) | 1976-01-20 |
DE2341180B2 (en) | 1975-09-25 |
US3925165A (en) | 1975-12-09 |
CH563456A5 (en) | 1975-06-30 |
FR2196388A1 (en) | 1974-03-15 |
FR2196388B1 (en) | 1977-08-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PCNP | Patent ceased through non-payment of renewal fee |