EP4349348C0 - Mittel zur verwendung bei der verbesserung der krebs-kachexie und verfahren zur verbesserung von krebskachexie - Google Patents

Mittel zur verwendung bei der verbesserung der krebs-kachexie und verfahren zur verbesserung von krebskachexie

Info

Publication number
EP4349348C0
EP4349348C0 EP22810821.3A EP22810821A EP4349348C0 EP 4349348 C0 EP4349348 C0 EP 4349348C0 EP 22810821 A EP22810821 A EP 22810821A EP 4349348 C0 EP4349348 C0 EP 4349348C0
Authority
EP
European Patent Office
Prior art keywords
cancer cachexia
improving cancer
improving
cachexia
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP22810821.3A
Other languages
English (en)
French (fr)
Other versions
EP4349348B1 (de
EP4349348A1 (de
EP4349348A4 (de
Inventor
Shoji Koga
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dexon Pharmaceuticals Inc
Original Assignee
Dexon Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dexon Pharmaceuticals Inc filed Critical Dexon Pharmaceuticals Inc
Publication of EP4349348A1 publication Critical patent/EP4349348A1/de
Publication of EP4349348A4 publication Critical patent/EP4349348A4/de
Application granted granted Critical
Publication of EP4349348B1 publication Critical patent/EP4349348B1/de
Publication of EP4349348C0 publication Critical patent/EP4349348C0/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
EP22810821.3A 2021-05-27 2022-01-17 Mittel zur verwendung bei der verbesserung der krebs-kachexie und verfahren zur verbesserung von krebskachexie Active EP4349348B1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2021088875A JP6974892B1 (ja) 2021-05-27 2021-05-27 癌悪液質の改善剤および癌悪液質の改善方法
PCT/JP2022/001255 WO2022249535A1 (ja) 2021-05-27 2022-01-17 癌悪液質の改善剤および癌悪液質の改善方法

Publications (4)

Publication Number Publication Date
EP4349348A1 EP4349348A1 (de) 2024-04-10
EP4349348A4 EP4349348A4 (de) 2024-10-16
EP4349348B1 EP4349348B1 (de) 2026-04-01
EP4349348C0 true EP4349348C0 (de) 2026-04-01

Family

ID=78766802

Family Applications (1)

Application Number Title Priority Date Filing Date
EP22810821.3A Active EP4349348B1 (de) 2021-05-27 2022-01-17 Mittel zur verwendung bei der verbesserung der krebs-kachexie und verfahren zur verbesserung von krebskachexie

Country Status (5)

Country Link
US (2) US20240216441A1 (de)
EP (1) EP4349348B1 (de)
JP (1) JP6974892B1 (de)
CN (1) CN117355316B (de)
WO (1) WO2022249535A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116171158A (zh) * 2020-09-08 2023-05-26 Dexon制药株式会社 细胞因子风暴抑制剂、细胞因子风暴抑制剂的使用方法和筛选方法
JP2023155687A (ja) * 2022-04-11 2023-10-23 Dexonファーマシューティカルズ株式会社 微小粒子、うつ病の予防薬または治療薬およびうつ病の改善方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2164514T3 (en) 2007-05-21 2017-02-27 Alderbio Holdings Llc Antibodies to IL-6 and its use
US20130195991A1 (en) * 2010-03-26 2013-08-01 National University Corporation Nagoya University Composition for Treatment of Damaged Part
CA2824515C (en) 2011-01-18 2022-09-13 Bioniz, Llc Compositions and methods for modulating gamma-c-cytokine activity
EP3389788A4 (de) 2015-12-18 2019-07-17 University of Pittsburgh- Of the Commonwealth System of Higher Education Prävention und therapie von krebs durch hemmung des löslichen tumornekrosefaktors
US20170258843A1 (en) * 2016-03-14 2017-09-14 AngioStem, Inc. Stem cell mediated neuroregeneration and neuroprotection
KR20190007040A (ko) * 2016-05-16 2019-01-21 엑소스템 바이오텍 리미티드 간엽 줄기 세포 및 근육 손상 및 근육-관련된 질환의 치료를 위한 이의 용도
JP2018023343A (ja) 2016-08-12 2018-02-15 国立大学法人山口大学 細胞培養用培地、及び細胞培養方法
JP7014449B2 (ja) 2016-08-14 2022-02-01 ラモット アット テル アビブ ユニバーシティ, リミテッド 神経障害を処置するための間葉系細胞由来エキソソーム
AU2017354272A1 (en) * 2016-11-03 2019-05-23 Exostem Biotec Ltd. Mesenchymal stem cells populations, their products, and use thereof
US20180133258A1 (en) * 2016-11-16 2018-05-17 Creative Medical Health, Llc Treatment of cachexia using stem cells and products thereof
CN106492194A (zh) * 2016-11-30 2017-03-15 广州赛莱拉干细胞科技股份有限公司 一种干细胞外泌体制剂及其制备方法和应用
EP3630836A1 (de) 2017-05-31 2020-04-08 Elstar Therapeutics, Inc. Multispezifische moleküle, die an myeloproliferatives leukämie (mlp)-protein binden, und deren verwendungen
CN111467373A (zh) * 2020-04-24 2020-07-31 西安交通大学 一种牙髓干细胞外泌体制剂、制备方法及其应用
JP6894652B1 (ja) * 2020-09-08 2021-06-30 デクソンファーマシューティカルズ株式会社 組織修復剤、組織修復剤の使用方法およびスクリーニング方法
CN116171158A (zh) * 2020-09-08 2023-05-26 Dexon制药株式会社 细胞因子风暴抑制剂、细胞因子风暴抑制剂的使用方法和筛选方法
CN112458045A (zh) * 2020-11-30 2021-03-09 南京医科大学附属口腔医院 一种牙源性干细胞的培养与外泌体分离方法

Also Published As

Publication number Publication date
EP4349348B1 (de) 2026-04-01
JP2022181747A (ja) 2022-12-08
CN117355316A (zh) 2024-01-05
US20240216441A1 (en) 2024-07-04
JP6974892B1 (ja) 2021-12-01
EP4349348A1 (de) 2024-04-10
CN117355316B (zh) 2025-02-14
US20240424029A1 (en) 2024-12-26
WO2022249535A1 (ja) 2022-12-01
EP4349348A4 (de) 2024-10-16

Similar Documents

Publication Publication Date Title
EP4342259A4 (de) Verfahren und vorrichtung zur verwendung in wlan-netzwerken
EP4456662C0 (de) Verfahren und vorrichtung zur verwendung von harq in der drahtlosen kommunikation
EP4063523C0 (de) Zusammensetzung, kit, verfahren zur detektion von sars-cov-2 und verwendung davon
EP4304567A4 (de) Gezielte therapeutische lipidnanopartikel und verfahren zur verwendung
EP4422645A4 (de) Oligonukleotidzusammensetzungen und verfahren zur verwendung davon
EP4173628A4 (de) Mittel zur verbesserung der hodenfunktion und verfahren zur verbesserung der hodenfunktion
EP3947896C0 (de) Automatisiertes system und verfahren zur verwendung in der bohrlochsteuerung
EP4370038A4 (de) Verfahren und vorrichtungen zur nervenregeneration
EP4405358A4 (de) Fgfr-inhibitoren und verfahren zur verwendung davon
EP4196133A4 (de) Verfahren und zusammensetzungen zur stimulierung von gamma-delta-t-zellen
EP4522583A4 (de) Pi3k-alpha-hemmer und verfahren zur verwendung davon
EP4449030C0 (de) Verfahren zur vermessung von heliostaten und verfahren zur kalibrierung von heliostaten
EP4490208A4 (de) Polyzitterionische komplexe und verfahren zur verwendung davon
EP4437104A4 (de) Komplementfaktor-b-modulierende zusammensetzungen und verfahren zur verwendung davon
EP4408525A4 (de) Angiotensinogenmodulierende zusammensetzungen und verfahren zur verwendung davon
EP4294804C0 (de) Pyridonverbindungen und verfahren zur verwendung
EP4408442A4 (de) Antikörperbeladene immunzellen und verfahren zur verwendung bei der krebsbehandlung
EP4252408C0 (de) Verfahren zur erstellung und zum vergleich von farbprofilen
EP4412617A4 (de) Neuartige pikfyve-hemmer und verfahren zur verwendung davon
EP4433498A4 (de) Vektoren zur erhöhung der nprl2-expression in krebszellen und verfahren zur verwendung davon
EP4531476A4 (de) Verfahren und vorrichtung zur verwendung in der drahtlosen kommunikation
EP3755697A4 (de) Degrader von egfr und verfahren zur verwendung davon
EP4609600A4 (de) Verfahren und nichttransitorisches computerlesbares speichermedium zur durchführung von subblockbasierter interprädiktion
EP4430200A4 (de) Selbstverstärkende rna-zusammensetzungen und verfahren zur verwendung davon
EP4355331A4 (de) Verfahren und zusammensetzungen zur melanombehandlung

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20231109

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20240917

RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 43/00 20060101ALI20240911BHEP

Ipc: A61P 7/06 20060101ALI20240911BHEP

Ipc: A61K 35/28 20150101ALI20240911BHEP

Ipc: A61P 35/00 20060101ALI20240911BHEP

Ipc: A61P 7/00 20060101ALI20240911BHEP

Ipc: A61P 3/00 20060101ALI20240911BHEP

Ipc: A61K 35/32 20150101AFI20240911BHEP

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: EXAMINATION IS IN PROGRESS

17Q First examination report despatched

Effective date: 20250506

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: GRANT OF PATENT IS INTENDED

INTG Intention to grant announced

Effective date: 20251020

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE PATENT HAS BEEN GRANTED

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

REG Reference to a national code

Ref country code: CH

Ref legal event code: F10

Free format text: ST27 STATUS EVENT CODE: U-0-0-F10-F00 (AS PROVIDED BY THE NATIONAL OFFICE)

Effective date: 20260401

Ref country code: GB

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: DE

Ref legal event code: R096

Ref document number: 602022033650

Country of ref document: DE

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

U01 Request for unitary effect filed

Effective date: 20260401

U07 Unitary effect registered

Designated state(s): AT BE BG DE DK EE FI FR IT LT LU LV MT NL PT RO SE SI

Effective date: 20260414