EP4093452A1 - Produit médicinal pour libération de médicament à effet amélioré - Google Patents

Produit médicinal pour libération de médicament à effet amélioré

Info

Publication number
EP4093452A1
EP4093452A1 EP21701470.3A EP21701470A EP4093452A1 EP 4093452 A1 EP4093452 A1 EP 4093452A1 EP 21701470 A EP21701470 A EP 21701470A EP 4093452 A1 EP4093452 A1 EP 4093452A1
Authority
EP
European Patent Office
Prior art keywords
balloon
medical device
solution
active ingredient
paclitaxel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP21701470.3A
Other languages
German (de)
English (en)
Inventor
Ole Gemeinhardt
Sebastian SCHURMANN-KAUFELD
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Charite Universitaetsmedizin Berlin
Innora GmbH
Original Assignee
Charite Universitaetsmedizin Berlin
Innora GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Charite Universitaetsmedizin Berlin, Innora GmbH filed Critical Charite Universitaetsmedizin Berlin
Publication of EP4093452A1 publication Critical patent/EP4093452A1/fr
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/958—Inflatable balloons for placing stents or stent-grafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606—Coatings

Abstract

L'invention concerne un dispositif médical destiné à venir en contact au moins temporairement avec des vaisseaux malades, tels que par exemple un stent ou un cathéter à ballonnet, ainsi qu'un procédé de revêtement d'un tel dispositif avec une solution définie. Selon l'invention, un inhibiteur de resténose ayant une concentration en principe actif supérieure à 4 µg/mm2 est présent sur une surface extérieure.
EP21701470.3A 2020-01-20 2021-01-20 Produit médicinal pour libération de médicament à effet amélioré Pending EP4093452A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102020101197.0A DE102020101197A1 (de) 2020-01-20 2020-01-20 Medizinprodukt zur Arzneimittelabgabe mit verstärkter Wirkung
PCT/EP2021/051156 WO2021148445A1 (fr) 2020-01-20 2021-01-20 Produit médicinal pour libération de médicament à effet amélioré

Publications (1)

Publication Number Publication Date
EP4093452A1 true EP4093452A1 (fr) 2022-11-30

Family

ID=74215932

Family Applications (1)

Application Number Title Priority Date Filing Date
EP21701470.3A Pending EP4093452A1 (fr) 2020-01-20 2021-01-20 Produit médicinal pour libération de médicament à effet amélioré

Country Status (6)

Country Link
US (1) US20230065280A1 (fr)
EP (1) EP4093452A1 (fr)
JP (1) JP2023520837A (fr)
CN (1) CN115397481A (fr)
DE (1) DE102020101197A1 (fr)
WO (1) WO2021148445A1 (fr)

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10244847A1 (de) 2002-09-20 2004-04-01 Ulrich Prof. Dr. Speck Medizinische Vorrichtung zur Arzneimittelabgabe
WO2007011707A2 (fr) * 2005-07-15 2007-01-25 Micell Technologies, Inc. Enrobages polymeres renfermant de la poudre de medicament a morphologie commandee
US8425459B2 (en) * 2006-11-20 2013-04-23 Lutonix, Inc. Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent
CN101011607A (zh) * 2007-01-12 2007-08-08 李艳芳 显影聚乳酸类微球型血管栓塞剂
NZ588816A (en) * 2007-01-21 2011-11-25 Hemoteq Ag Medical device for the treatment of stenoses of corporal lumina and for the prevention of impending restenoses
DE102007036685A1 (de) * 2007-08-03 2009-02-05 Innora Gmbh Verbesserte arzneimittelbeschichtete Medizinprodukte deren Herstellung und Verwendung
DE102007040868A1 (de) * 2007-08-29 2009-04-16 Innora Gmbh Ballonkatheter mit Schutz vor Auffaltung
EP2380604A1 (fr) 2010-04-19 2011-10-26 InnoRa Gmbh Formulations de revêtement améliorées pour strier ou découper des cathéters à ballonnet
DE102010022588A1 (de) * 2010-05-27 2011-12-01 Hemoteq Ag Ballonkatheter mit einer partikelfrei Wirkstoff-abgebenden Beschichtung
EP4049707B1 (fr) 2012-12-31 2024-03-27 Clearstream Technologies Limited Cathéter à ballonnet avec marquage radio-opaque transitoire
DE102013110294B4 (de) * 2013-09-18 2016-07-07 Innora Gmbh Limus-Depot-Formulierung auf Ballonkathetern
CN104174073B (zh) * 2014-08-27 2016-07-06 辽宁生物医学材料研发中心有限公司 一种药物洗脱球囊导管的载药方法
CN113679931A (zh) 2015-01-22 2021-11-23 因特尔赛克特耳鼻喉公司 药物涂覆的气囊
CN104984412A (zh) * 2015-05-12 2015-10-21 湘潭大学 一种药物球囊表面紫杉醇涂层的制备方法
EP3413964A4 (fr) * 2016-02-08 2019-12-04 Orbusneich Medical Pte. Ltd Ballonnet à élution de médicament
JP2019522540A (ja) 2016-06-24 2019-08-15 ダブリュ．エル．ゴア アンド アソシエイツ，インコーポレイティドＷ．Ｌ． Ｇｏｒｅ ＆ Ａｓｓｏｃｉａｔｅｓ， Ｉｎｃｏｒｐｏｒａｔｅｄ 薬物で被覆されたバルーン及び血管透過性を高める技術
DE102019116791B4 (de) * 2019-06-21 2023-10-26 InnoRa Gesellschaft mbH Stent mit sofort ablösbarer Beschichtung
CN110292701B (zh) * 2019-06-27 2021-11-16 山东瑞安泰医疗技术有限公司 一种药物洗脱球囊导管及其制备方法

Also Published As

Publication number Publication date
WO2021148445A1 (fr) 2021-07-29
DE102020101197A1 (de) 2021-07-22
CN115397481A (zh) 2022-11-25
US20230065280A1 (en) 2023-03-02
JP2023520837A (ja) 2023-05-22

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