EP4088721A4 - Composition de traitement du syndrome de l'x fragile ou des troubles du développement associés, comprenant un composé de lisuride en tant que principe actif - Google Patents

Composition de traitement du syndrome de l'x fragile ou des troubles du développement associés, comprenant un composé de lisuride en tant que principe actif Download PDF

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Publication number
EP4088721A4
EP4088721A4 EP21738899.0A EP21738899A EP4088721A4 EP 4088721 A4 EP4088721 A4 EP 4088721A4 EP 21738899 A EP21738899 A EP 21738899A EP 4088721 A4 EP4088721 A4 EP 4088721A4
Authority
EP
European Patent Office
Prior art keywords
fragil
lisuride
syndrome
compound
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP21738899.0A
Other languages
German (de)
English (en)
Other versions
EP4088721B1 (fr
EP4088721A1 (fr
Inventor
Sohyun JOO
Chanyoung SHIN
Sejin JEON
Taejin Ahn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Neuroventi
Original Assignee
Neuroventi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neuroventi filed Critical Neuroventi
Publication of EP4088721A1 publication Critical patent/EP4088721A1/fr
Publication of EP4088721A4 publication Critical patent/EP4088721A4/fr
Application granted granted Critical
Publication of EP4088721B1 publication Critical patent/EP4088721B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
    • A23V2200/322—Foods, ingredients or supplements having a functional effect on health having an effect on the health of the nervous system or on mental function
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00—Food ingredients
    • A23V2250/30—Other Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Mycology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Non-Alcoholic Beverages (AREA)
EP21738899.0A 2020-01-08 2021-01-08 Composition de traitement du syndrome de l'x fragile ou des troubles du développement associés, comprenant un composé de lisuride en tant que principe actif Active EP4088721B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20200002576 2020-01-08
PCT/KR2021/000227 WO2021141426A1 (fr) 2020-01-08 2021-01-08 Composition de traitement du syndrome de l'x fragile ou des troubles du développement associés, comprenant un composé de lisuride en tant que principe actif

Publications (3)

Publication Number Publication Date
EP4088721A1 EP4088721A1 (fr) 2022-11-16
EP4088721A4 true EP4088721A4 (fr) 2024-01-10
EP4088721B1 EP4088721B1 (fr) 2025-09-17

Family

ID=76788829

Family Applications (1)

Application Number Title Priority Date Filing Date
EP21738899.0A Active EP4088721B1 (fr) 2020-01-08 2021-01-08 Composition de traitement du syndrome de l'x fragile ou des troubles du développement associés, comprenant un composé de lisuride en tant que principe actif

Country Status (6)

Country Link
US (1) US20230024384A1 (fr)
EP (1) EP4088721B1 (fr)
JP (1) JP7490064B2 (fr)
KR (2) KR102528677B1 (fr)
CN (1) CN115335053B (fr)
WO (1) WO2021141426A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022079302A1 (fr) * 2020-10-16 2022-04-21 Purposeful Ike Compositions et utilisations associées

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2359128A1 (de) * 1973-11-24 1975-06-12 Schering Ag Arzneimittel auf basis von lisurid und dessen physiologisch vertraeglichen salzen
WO2007117687A2 (fr) * 2006-04-06 2007-10-18 Nupathe Inc. Implants destines au traitement d'etats associes a la dopamine
WO2008134123A1 (fr) * 2007-04-30 2008-11-06 The Uab Research Foundation Ul97 utilisé pour traiter des troubles liés aux agrégats formés par les protéines
WO2010015037A1 (fr) * 2008-08-08 2010-02-11 Howard Florey Institute Procédés et compositions thérapeutiques
KR20130043197A (ko) * 2010-07-20 2013-04-29 파이토팜 피엘씨 엘-도파, 도파민 효능제 및/또는 도파민 증강제 유도된 장애의 치료
RU2013126522A (ru) * 2010-11-11 2014-12-20 Зинокса Фарма Уг Лизурид, тергурид и их производные для применения в профилактике и/или лечении фиброзных изменений
TW201606304A (zh) * 2013-09-09 2016-02-16 亞克柏拉有限公司 測定治療反應之方法
TW201613864A (en) * 2014-02-20 2016-04-16 Takeda Pharmaceutical Novel compounds
GB2550110A (en) * 2016-04-28 2017-11-15 Univ Oxford Innovation Ltd Treatment of impulsivity-related disorders
HUE068300T2 (hu) * 2017-01-20 2024-12-28 Prilenia Neurotherapeutics Ltd Pridopidin törékeny X szindróma kezelésében történõ alkalmazásra
WO2022079302A1 (fr) * 2020-10-16 2022-04-21 Purposeful Ike Compositions et utilisations associées

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SHAFIQ SAMREEN ET AL: "Using antipsychotics for behavioral problems in children", EXPERT OPIN PHARMACOTHER, vol. 19, no. 13, 13 August 2018 (2018-08-13), London, UK, pages 1475 - 1488, XP093105595, ISSN: 1465-6566, DOI: 10.1080/14656566.2018.1509069 *

Also Published As

Publication number Publication date
KR102600350B1 (ko) 2023-11-09
KR20230023692A (ko) 2023-02-17
KR102528677B1 (ko) 2023-05-04
KR20210089595A (ko) 2021-07-16
EP4088721B1 (fr) 2025-09-17
CN115335053B (zh) 2024-08-09
WO2021141426A1 (fr) 2021-07-15
CN115335053A (zh) 2022-11-11
US20230024384A1 (en) 2023-01-26
JP7490064B2 (ja) 2024-05-24
EP4088721A1 (fr) 2022-11-16
JP2023523119A (ja) 2023-06-02

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