Classifications

• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
  • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
  • A61F2/02—Prostheses implantable into the body
  • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
  • A61F2/06—Blood vessels
  • A61F2/07—Stent-grafts
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
  • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
  • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
  • A61F2/852—Two or more distinct overlapping stents
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
  • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
  • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
  • A61F2/962—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve
  • A61F2/966—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
  • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
  • A61F2/02—Prostheses implantable into the body
  • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
  • A61F2/06—Blood vessels
  • A61F2002/061—Blood vessels provided with means for allowing access to secondary lumens
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
  • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
  • A61F2/02—Prostheses implantable into the body
  • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
  • A61F2/06—Blood vessels
  • A61F2002/065—Y-shaped blood vessels
  • A61F2002/067—Y-shaped blood vessels modular
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
  • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
  • A61F2/02—Prostheses implantable into the body
  • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
  • A61F2/06—Blood vessels
  • A61F2/07—Stent-grafts
  • A61F2002/075—Stent-grafts the stent being loosely attached to the graft material, e.g. by stitching
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
  • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
  • A61F2/02—Prostheses implantable into the body
  • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
  • A61F2/06—Blood vessels
  • A61F2/07—Stent-grafts
  • A61F2002/077—Stent-grafts having means to fill the space between stent-graft and aneurysm wall, e.g. a sleeve
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
  • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
  • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
  • A61F2002/821—Ostial stents
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
  • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
  • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
  • A61F2002/828—Means for connecting a plurality of stents allowing flexibility of the whole structure
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
  • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
  • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
  • A61F2/962—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve
  • A61F2/966—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod
  • A61F2002/9665—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod with additional retaining means
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
  • A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
  • A61F2220/0025—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
  • A61F2220/0091—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements connected by a hinged linkage mechanism, e.g. of the single-bar or multi-bar linkage type
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
  • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
  • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
  • A61F2250/006—Additional features; Implant or prostheses properties not otherwise provided for modular

Definitions

• the present invention relates to a vascular prosthesis for a blood vessel of a patient, which has the following: a hollow cylindrical base body with a stent frame and an attached prosthesis material, the base body having a longitudinal axis, an inside and an outside, and a proximal end with a proximal Has opening and a distal end with a distal opening.
• vascular prostheses of this type are already known in the prior art.
• vascular prostheses which are also referred to as endovascular vascular stents / stent grafts, Endopro theses or endo-grafts, for the treatment of weakened, injured, torn or aneurysmal vessels.
• the aim of the endoluminal treatment of an aneurysm is the complete pressure relief of the diseased vessel section in order to reliably avoid a rupture. This requires the prosthesis to be sealed against the switched-off lumen throughout the course, but especially in the area of the anchoring zones.
• vascular prosthesis or stent graft is released at the diseased or injured part of the vessel, which restores the functionality of the original vessel or supports the vascular integrity that still exists.
• the implant effects a correction or shielding of the lesion and / or a redirection of the blood flow. In this way, the blood now flows through the vascular prosthesis and further stress on the sac is prevented.
• the radial force of the vascular prosthesis is often sufficient for anchoring in the vessels.
• An aneurysm is understood to mean a widening or bulging of an arterial blood vessel as a result of congenital or acquired wall changes.
• the bulge can thereby capture the vessel wall as a whole, or, as with the so-called false aneurysm or the so-called dissection, blood escapes from the lumen of the vessel between the vessel wall layers and shears them apart. If an aneurysm is not treated at an advanced stage, the artery can rupture, with the result that the patient bleeds internally.
• Vascular prostheses generally consist of a hollow cylindrical metal frame or framework made of stainless steel or a metal alloy (usually made of a shape memory material; e.g. Nitinol), these usually consisting of a wire mesh or of so-called stent springs arranged one behind the other, so-called stent springs possibly connected to one another via connecting supports made of wire, or which are only connected to one another via the prosthesis material, exist.
• the outer surface of the hollow cylindrical metal frame is often covered with a textile or polymer film, so that a hollow cylindrical body results.
• the jacket is usually made of polyester (Dacron) or polytetrafluoroethylene (PTFE).
• the metal framework is often sewn to the prosthesis material with non-absorbable suture material.
• vascular prostheses are available in diameters between 18 and 46 mm and jacketed lengths between 90 and 250 mm. These can be extended proximally or distally using additional prostheses.
• customized vascular prostheses are known.
• the vascular prostheses are usually already pre-assembled in the delivery system when they are purchased. The vascular prosthesis is then introduced into the affected vessel by means of this introduction system via a stiff guide wire.
• the vascular prostheses are in their proximal end regions (10 to 20 mm) without sheathing ("bare springs").
• the “bare springs” secure the anchoring within the delivery system.
• the “bare springs” are therefore necessary during the implantation of the vascular prosthesis, in this case the insertion system is connected to the exposed stent rings of the vascular prosthesis, so that a targeted expansion of the vascular prosthesis can be ensured at the desired location.
• the vascular prosthesis is compressed radially so that its
• the vascular prosthesis is located in the distal end of the sheath catheter of the delivery system and can be released by slowly withdrawing the sheath catheter.
• the vascular prosthesis is first brought into the area of the aneurysm with the help of an insertion system, where it can be released in the correct position.
• the proximal stent graft springs are fixed in the delivery system.
• the first, i.e. proximally terminal, stent spring is hooked into a locking mechanism. This is usually possible because the first stent spring protrudes proximally from the stent graft and has no prosthetic material in this area.
• the first stent spring is held together in the delivery system and can be released at any time by actuating the release mechanism at the proximal end of the delivery system.
• the correct position of the stents can be checked using X-ray markers which are provided on the jacket of the stent, in particular in the area of the opening for supplying the branching blood vessels or in the area of the proximal and distal ends.
• the proximal fixation of the vascular prosthesis is generally preferably achieved by a stent spring protruding from the textile sheath. It has been shown that this can result in numerous disadvantages. For example, vascular injuries often occur that are triggered by exposed, often pointed stent springs, so that in the worst case a new aneurysm can develop. Furthermore, there is the risk that the sheath catheter and the guide wires can get caught by a free stent spring or be “threaded” onto them. The consequence would be a dislocation of the vascular prosthesis and / or a malfunction of the vascular prosthesis. In addition, the exposed springs can also damage existing vascular prostheses.
• Partial unfolding is also not possible with such vascular prostheses, so that the blood flow is completely blocked during implantation.
• a critical point is that the vascular prosthesis, once it is released, can no longer be rotated or moved or displaced in the vessel in order to position it correctly if necessary otherwise there is a risk of damage to the vessels.
• the insertion systems known according to the prior art have precisely this disadvantage. This is particularly critical in the case of vascular prostheses with side branches, since these should extend into the branching blood vessels after the vascular prosthesis has been released.
• vascular prostheses known in the prior art are designed, for example, in such a way that the proximal stent spring is also sewn around with prosthetic material.
• the fixation of the vascular prosthesis on the delivery system, which is necessary for its insertion into the vessel to be treated, is ensured by loops that are located inside the wood-cylindrical base body.
• vascular prosthesis leads to unnecessary material accumulation / packing density in the proximal loading area, which necessitates a larger catheter diameter. Consequently, patients with narrower vessels cannot be treated as a result.
• a further disadvantage of these vascular prostheses is that the guide hooks of the insertion system can get caught in the loops and the vascular prosthesis can move when it is released. In addition, it can lead to increased thrombus formation, as blood components can adversely accumulate on the loops that are exposed.
• vascular prostheses which are used for implantation in vessels and for the treatment of vascular diseases can be.
• the vascular prostheses should be designed in such a way that simplified loading of the vascular prosthesis onto the insertion catheter as well as simple insertion of the vascular prosthesis into the affected vessel can be made possible.
• vascular prosthesis and a suitable insertion system with the help of which the vascular prosthesis can be easily loaded, compressed, inserted and released in such a way that the possibility of correct placement of the stents immediately before the final release consists.
• a vascular prosthesis for a blood vessel of a patient which has the following: a hollow cylindrical base body with a stent frame and a prosthesis material attached to it, the base body having a longitudinal axis (L), an inside and an outside, as well as a has a proximal end with a proximal opening and a distal end with a distal opening, with a first self-expanding end-standing stent ring being provided at the proximal end and / or distal end, which can be converted from a compressed state into an expanded state, the first stent ring is meandering and has pointed arches and webs connecting them, and wherein the first stent ring is attached to the outside of the base body on the prosthesis material in such a way that no pointed arch of the first stent ring protrudes freely beyond the proximal and / or distal end, and furthermore at least a thread element the first stent ring is provided,
• an insertion system for introducing a vascular prosthesis having at least one terminal stent ring into a vessel of a patient, the insertion system comprising: a catheter tube onto which the vascular prosthesis can be loaded for insertion into the blood vessel, a retraction sheath to the Compression of the vascular prosthesis in its charged state, an axially movable fixation on the catheter tube, at least one thread element via which the terminal stent ring of the vascular prosthesis can be compressed or expanded by tensile loading or strain relief.
• the object of the invention is also achieved by a method for introducing a vascular prosthesis into a blood vessel of a patient with the aid of the insertion system according to the invention with the following steps:
• the object is also achieved through the use of a vascular prosthesis according to the invention and / or an insertion system according to the invention for implantation in a blood vessel of a patient for the treatment of a vascular disease.
• the thread guide allows the openings of the vascular prosthesis to be opened in a controlled manner and, if necessary, closed again. An uncontrolled immediate expansion of the vascular prosthesis after the sheath catheter is withdrawn is thus avoided. Rather, the expansion is controlled so that with this vascular prosthesis, a targeted partial expansion up to complete expansion can be made possible in stages.
• the expansion is controlled by the thread guide and the pulling or loosening of the thread. It is particularly advantageous with this vascular prosthesis that, after it has been placed, rotation is also possible in order, for example, to precisely position any side branches of the vascular prosthesis that are provided in branching vessels.
• vascular prosthesis With the vascular prosthesis according to the invention, a new type of vascular prosthesis is provided which can be used to support unstable, brittle or thrombic vascular walls and in particular for the treatment of aneurysmal vessels.
• the special structure of the vascular prosthesis makes it possible for a surgeon to place the vascular prosthesis correctly in the injured vessel and to correct the position of the prosthesis if necessary.
• the hollow cylindrical one has a proximal end at the proximal end
• the opening angle or the degree of opening of the proximal and / or distal opening of the vascular prosthesis can be controlled via the at least one thread element, especially after the retraction of the rest of the vascular prosthesis previously held in a compressed state.
• This enables the user to first place the vascular prosthesis, which is, for example, held compressed in the compressed state by a retraction sheath in the compressed state, exactly in the vessel to be treated, then to expand the retraction sheath to expand the vascular prosthesis, with the opening or expansion of the proximal and / or distal opening of the vascular prosthesis via which at least one thread element can be controlled.
• the vascular prosthesis according to the invention offers the advantage that the thread element, which enables a targeted expansion of the opening of the vascular prosthesis, after Expansion is anchored to the vascular prosthesis in such a way that it cannot get caught in the insertion system and thus a dislocation of the vascular prosthesis is prevented.
• the vascular prosthesis according to the invention has the advantage that it can do without the so-called “bare springs", as discussed at the beginning, since the vascular prosthesis is such that the proximal opening can terminate essentially flush with the prosthesis material.
• the vascular prosthesis according to the invention is used as a vascular prosthesis which, with its proximal and / or distal end, ie the end at which the thread element is located, is partially inserted into a further vascular prosthesis for anchoring therein, whereby the vascular prosthesis becomes a “stent in the stent ”or a so-called“ secondary ”stent.
• the vascular prosthesis according to the invention avoids damage which can occur in two vascular prostheses, known from the prior art, which are guided into one another by their exposed stent rings / stent springs in the overlapping area.
• the first stent ring is a support element which is arranged perpendicular to the longitudinal direction at the proximal and / or distal end of the vascular prosthesis and is circumferential in a meandering manner and closed in a ring-like manner.
• the first stent ring has stent springs which are formed from pointed arches and webs connecting them.
• “meander-shaped” is understood to mean any loop-shaped or loop-shaped course of a stent ring.
• pointed arches or points are formed, which point alternately in the proximal and distal direction, and which are connected to one another via straight webs or legs.
• a stent ring has at least 4 pointed arches pointing in one (ie either in the proximal or distal) direction, in particular at least or exactly 4, 5, 6, 7, 8, or 9.
• stent or “stent element”, “stent spring” or “stent ring” refers to any structure which gives a vascular prosthesis an expansion force and / or a supporting function. Accordingly, a stent element is therefore any element that has the properties of the stent.
• stent spring and stent ring are used alternately here.
• a stent ring is understood to mean any one-piece, annular element which can be compressed due to its material and can expand again like a spring after the compression pressure has been removed.
• the stent springs / rings have a wave-like circuit, with wave crests and wave troughs forming one phase and alternating with one another.
• the at least one terminal stent ring is not connected to the rest of the stent structure of the vascular prosthesis, but is merely attached to the prosthesis material, preferably sewn on. It is preferred here if the first terminal stent ring is not attached to the prosthesis material over its entire material surface, but rather is attached to the prosthesis material only over certain sections, for example only in the area of the pointed arches, so that the webs that connect the pointed arches to one another are essentially not attached or sewn directly to the prosthesis material.
• the stent ring can have the same or different circumferential amplitudes distributed over its circumference, which result from the legs of the stent springs of the same length or of different lengths. Amplitudes of different lengths offer the advantage that the stent graft can be adapted to the respective vessels and the respective properties (curvature, releasing vessels, tapering, etc.).
• the vascular prosthesis has a stent framework which, according to a preferred embodiment, extends over the entire length of the vascular prosthesis and which is connected to the prosthesis material over the entire length.
• distal denotes the part of the vascular prosthesis, or denotes the end which is located further downstream with respect to the blood flow.
• proximal denotes, again in relation to the blood flow, a part or the end which lies further upstream in relation to the blood flow.
• distal means guided / present in the direction of the blood flow and the term “proximal” means guided / present opposite to the direction of the blood flow.
• distal denotes the end of the catheter or insertion system that is inserted into the patient or that is furthest away from the user, and the term “proximal” the end that is closer to the user.
• terminal therefore means either the proximal or distal end of the vascular prosthesis, unless specifically designated.
• the attachment of the first thread element to the vascular prosthesis can for example be effected by sewing, knotting and / or gluing the first thread end to the vascular prosthesis, in particular to the vascular prosthesis material and / or the stent ring.
• a "thread element” is understood to mean a thread or a cord with a certain length and with a first end and a second end, and in particular any pliable and inelastic structure made of plastic or metals that is twisted has dominant one-dimensional extent and uniformity in the longitudinal direction, while having a first end, a second end and a certain length.
• a second terminal stent ring is provided at the proximal and / or distal end, which via the compression or Expansion of the first stent ring can be converted from a compressed state to an expanded state, the second stent ring running around in a meandering shape and having pointed arches and webs connecting them, and the second stent ring being attached to the inside of the base body on the prosthesis material in such a way that no pointed arches of the second stent ring protrudes freely beyond the proximal and / or distal end.
• the pointed arches of the first and the second terminal stent ring are not superimposed on the proximal and / or distal end on the inside and the outside of the base body, so that the first and second terminal stent ring, separated by the Overlap the prosthesis material only on the bars, but not on the pointed arches.
• This embodiment offers the advantage that the at least one end section is additionally stabilized by the second terminal stent ring.
• Thread element is firmly fixed with its first end in an area on the vascular prosthesis in which the first and / or second terminal stent ring is attached to the prosthesis material.
• the at least one thread element can also be firmly fixed, for example sewn, knotted and / or glued to the first or second terminal stent ring with the same seam via a seam which attaches the first and / or second terminal stent ring to the prosthetic material .
• the length of the at least one thread element preferably corresponds to the length of an imaginary line which connects at least two, preferably three pointed arches pointing in the same (ie in the proximal or in the distal) direction.
• Preferred thread element lengths are between approximately 10 mm and 100 mm, in particular between 10 mm and 50 mm.
• the diameter of the thread element can be between approximately or precisely 0.05 mm to approximately or precisely 1 mm.
• the degree of opening of the vascular prosthesis can advantageously be controlled by the length of the at least one thread element.
• the at least one thread element is circumferentially guided in the first end stent ring of the vascular prosthesis partially, that is, via its second free end, which is not firmly fixed to the vascular prosthesis.
• “circumferentially” means that the thread element is guided perpendicular to the longitudinal direction of the vascular prosthesis, that is to say in the circumferential direction of the vascular prosthesis.
• movably guided or “movably attached” means that the thread element is only fixed to the vascular prosthesis via its first end and is not firmly fixed to the prosthesis material and / or to the stent ring over its remaining length, in particular not its second end , but essentially - ie in a predetermined clearance or path - is freely guided in such a way that the thread element compresses the terminal stent ring by tensile load thereon and can close or reduce the vascular prosthesis opening comprising the stent ring and the thread element, as well as the end permanent stent ring can expand by strain relief and the vascular prosthesis opening can open or enlarge.
• the at least one thread element is guided from its fixed first end in one of the circumferential directions of the vascular prosthesis, i.e. to the right or to the left, whereby according to a further preferred embodiment the at least one thread element is regularly or irregularly alternating above and below the webs of the stent ring is available. According to a preferred embodiment, the thread element is guided at least partially and / or at one or more points in a circumferential direction of the vascular prosthesis in a predetermined area.
• the at least one thread element is present with its second end guided through a deflection.
• "Deflection” here means any element through which the thread element can be guided and / or pulled in a direction that differs from the circumferential direction, which is specified based on the fixing point of the first end of the thread element, for example is opposite, and / or points in the direction of the longitudinal axis.
• the specified area or the deflection through which the thread element is partially guided can be limited or “specified”, for example, by seams and / or loops in the prosthesis material. This keeps the thread element in the predetermined area.
• the at least one thread element is guided at at least one point in the circumferential direction of the terminal stent ring between two spaced seams, preferably through two spaced apart seams via which the stent ring is attached to the prosthesis material.
• this embodiment has the advantage that a deflection of the circumferentially guided thread element is created:
• the thread element is firmly fixed with its first end on the vascular prosthesis and is moved in one direction of the circumference (right or left) guided over and under the webs of the first terminal stent ring and away from the fixing point of the first end of the thread element;
• the thread element can then be deflected in a different direction, whereby the stent ring can be compressed or the opening of the vascular prosthesis can be reduced.
• This routing between two seams can take place at one point in the circumferential direction or at several points in the circumferential direction. Movement in the circumferential direction is always possible.
• the at least one thread element can be guided in a targeted manner and, if necessary, deflected in a different direction.
• the at least one thread element can furthermore be present in the manner of a weave, partially circumferentially around the vascular prosthesis.
• the at least one thread between the first stent ring and the prosthesis material is circumferentially “woven” or threaded in such a way that the thread element is alternately guided over and under the webs of the first terminal stent ring.
• the areas in which the at least one thread is to be guided can be specified by seams that connect the prosthesis material to the first stent ring.
• the alternating guiding over and under the webs of the first terminal stent ring can take place regularly, i.e. always alternately below and above the successive webs, or irregularly, e.g. over two successive webs and then under one web, etc.
• the second end of the thread element has a loop via which the thread can be releasably fixed to a vascular prosthesis release system.
• the loop can be formed, for example, by knotting or gluing the second end of the thread element in the form of a loop.
• the second end of the Fadenele element can be placed in a loop and fixed in the section in front of the second end of the Fadenele element on the thread element by knotting, gluing, welding or other fastening measures.
• the thread element can thus be releasably suspended in a fixing system.
• the vascular prosthesis according to the invention generally has two (end) states; the expanded and the compressed state, the compressed state being through compressing the vascular prosthesis over its longitudinal axis can be achieved, for example, by a retraction sheath which keeps the vascular prosthesis compressed in the state loaded onto an insertion catheter by surrounding it.
• the first terminal stent ring is also kept compressed - and thus separately or additionally - by tensile loading of the at least one thread element.
• the vascular prosthesis With the removal of the retraction sheath, the vascular prosthesis expands - except for the first terminal stent ring or the opening of the vascular prosthesis which has this stent ring and which can be opened separately by relieving the strain on the thread element.
• the at least one thread element is loosely guided around the vascular prosthesis partially (for example over a length of two to four pointed arches).
• the end of the at least one thread element, which is not firmly fixed to the vascular prosthesis, is thus exposed. This end can be designed as a loop for example. This makes it easier to pull on the thread and fix it to the introducer catheter.
• the loose, free second end of the thread element can be pulled / tensioned. This reduces the diameter of the respective distal and / or proximal opening of the vascular prosthesis. This shortens the distance between the attached end of the thread element and the area in which the thread element is freely present, which leads to the first stent ring being drawn together or compressed.
• the second free end of the thread element can be releasably attached to an insertion system for the vascular prosthesis, for example by hanging, for example, the second end designed as a loop into a fixing system provided for the thread element.
• the fixation system for the thread element can then be moved axially over the insertion catheter in such a way that the loop is released again so that strain relief is achieved and so that the first stent ring or the opening can expand.
• "Detachable" fastening means that in order to load the vascular prosthesis and to compress the at least one terminal stent ring, the second end of the thread element can be fastened to the insertion catheter or to a fixing system provided therein that it can, for example, be mechanically see influencing the insertion catheter or the fixation system for opening the at least one stent ring can be released from the fixation system again.
• a tensile load is understood in the present case to mean a tension or tension exerted on the thread element, with which the thread element at least partially compresses the stent ring.
• strain relief means that the thread element is guided on the vascular prosthesis without any tension or tension.
• the expansion of the terminal stent ring of the vascular prosthesis - and thus the opening at which the stent ring is located - can be achieved by targeted release of the second thread element end or by “loosening” or relieving it of the thread element can be controlled.
• the expansion of the terminal stent ring of the vascular prosthesis within a vessel can be steered through the fixation and loosening within the delivery system.
• the thread element lies circumferentially around the vascular prosthesis when the load is released, being guided under and / or over the webs of the stent ring, so that after expansion of the vascular prosthesis in the vessel, the thread element is also clamped between the vascular prosthesis and the vessel wall.
• the at least one thread element can be formed from the same material as the prosthesis material of the vascular prosthesis or have this, such as polyethylene terephthalate (PET), and / or from the same material as a suture material, with which the at least first terminal stent ring is attached to the prosthesis material, such as UHMWPE (ultra-high molecular weight polyethylene), and / or made of a superelastic material such as NiTi, as well as other common surgical suture materials.
• the hollow-cylindrical base body means the main body of the vascular prosthesis, which consists of a stent frame and at least partially of prosthesis material, at least one end being covered.
• the stent frame can in turn be constructed from individual, non-interconnected stent rings / springs, or from a stent frame that is braided or lasered and the elements of which are interconnected.
• the vascular prosthesis it is preferred if at least or exactly 2, at least or exactly 3, at least or exactly 4, at least or exactly 5, at least or exactly 6, at least or exactly 7, or at least on the first stent ring or there are exactly 8 thread elements, each of which is firmly fixed to the vascular prosthesis via its first end.
• the vascular prosthesis has 5 thread elements which are fastened to the vascular prosthesis, in particular in the area of the first stent ring, via their respective first thread element ends.
• the second, third and, if applicable, each further thread element can be firmly fixed to the vascular prosthesis via the first terminal stent ring, each with its first end.
• the individual thread elements preferably each have the same length and are provided distributed over the circumference of the stent ring, so that each The thread element spans a section of the stent ring, for example over two or three pointed arches, or is threaded over two or three pointed arches.
• About deflections provided for the individual Fadenele elements can then be compressed via the thread elements from each section of the stent ring under their tensile load.
• deflections corresponding to the number of thread elements are provided, that is to say preferably 2, 3, 4, 5, 6, 7 or 8.
• the respective free second ends of the thread elements are then releasably attached to the fixing system of an insertion system for compressing the first stent ring, for example via a loop formed at the second end.
• thread elements can also be provided in the area / on a / a stent ring (s) which is arranged directly adjacent to the first terminal in the direction of the other end of the vascular prosthesis.
• s a stent ring
• the length of the thread elements can also be used to determine their number: the longer the thread elements, the fewer are necessary to control the opening of the vascular prosthesis opening and also the compression.
• the vascular prosthesis has radiopaque markers.
• X-ray markers have the advantage that when the vascular prosthesis is implanted, the placement of the vascular prosthesis within the vessel can be monitored.
• the markers are preferably located on the proximal and / or on the distal end section of the vascular prosthesis.
• the X-ray markers are preferably sewn or glued to the prosthesis material. According to the invention, the marker either contains a radiopaque material or consists entirely of radiopaque material.
• the radiopaque markers are made of one or more several of the following materials, e.g. gold, palladium, tantalum, chromium, silver, etc .; the shape of the markers can be of any desired shape, for example round, square and / or, for example, in the form of letters, numbers or figures, which are helpful for the orientation of the vascular prosthesis in the vessel.
• the first and / or the second terminal stent ring has webs with the same length and / or different lengths.
• Pointed arches are provided which point towards the opening of the vascular prosthesis and which have a uniform height, as well as pointed arches which point away from the opening of the vascular prosthesis and which have an uneven height.
• This embodiment has the advantage that better compaction and thus less material accumulation can be achieved in the same places.
• the vascular prosthesis has branching off side branches.
• This embodiment is particularly preferred when the vessel to be treated has branching branches and a vascular prosthesis in this area would otherwise prevent the blood supply to the respective branch branches. Accordingly, the number of side branches of the vascular prosthesis depends on the number of the respective leaving the vessels of the vessel to be treated.
• the diameter of the vascular prosthesis is adapted to the respective blood vessel to be treated of a patient, so that the diameter of the vascular prosthesis corresponds approximately to the diameter of the blood vessel. This is to ensure that the vascular prosthesis, due to its self-expanding properties, becomes wedged in the vessel and cannot detach itself. If the diameter of the vascular prosthesis is selected to be too small, for example, then the vascular prosthesis can move unintentionally due to the blood flow.
• the prosthesis material has a material which is selected from a textile or a polymer, in particular has or is formed from this, which is selected from polyester, polyurethane, polystyrene, polytetrafluoroethylene, ultra-high molecular weight polyethylene (UHMPE) or mixtures thereof.
• a material which is selected from a textile or a polymer in particular has or is formed from this, which is selected from polyester, polyurethane, polystyrene, polytetrafluoroethylene, ultra-high molecular weight polyethylene (UHMPE) or mixtures thereof.
• UHMPE ultra-high molecular weight polyethylene
• the vascular prosthesis is designed to be self-expanding. It is preferred here if the stent frame and / or the first and / or second stent ring are made of a self-expanding material, for example nitinol.
• the stent frame has non-terminal stent rings which are distributed one behind the other over the hollow cylindrical base body and are attached to the prosthesis material on the inside and / or outside of the latter.
• non-terminal stent rings too, cannot be connected to one another, but rather represent individual stent rings which - analogously to the at least one terminal stent ring - are designed to run around in a meandering manner and have pointed arches and webs connecting them.
• the non-terminal stent rings can be firmly fixed on the outside and / or inside of the vascular prosthesis, for example by sutures or gluing or other suitable fastening means.
• the stent frame has a laser-cut or braided stent which is attached to the prosthesis material on the inside or outside of the hollow-cylindrical basic frame.
• the present invention also relates to an insertion system for inserting a vascular prosthesis according to the invention into a blood vessel of a patient, the insertion system having the following, a catheter tube onto which the vascular prosthesis can be loaded for insertion into the blood vessel, a Retraction sheath for compressing the vascular prosthesis in its loaded state, and an axially movable fixation on the Kathe terrohr, on which the at least one thread element of the vascular prosthesis is detachably attached.
• the fixation is designed in such a way that, via its axial displacement on the catheter tube, the at least one thread element compresses or relieves the first stent ring through tensile loading or strain relief, and via this possibly the second stent ring. can be expanded.
• FIG. 1A shows a schematic representation of a first embodiment of a vascular prosthesis according to the invention
• FIG. 1B shows a schematic representation of a second embodiment of a vascular prosthesis according to the invention
• FIGS. 1A and 1B shows an enlarged illustration of the proximal end region of the embodiments shown in FIGS. 1A and 1B;
• Fig. 2 is a schematic representation of a section of a vascular prosthesis according to the invention, with partially opened vascular prosthesis opening, with the Fa den 1952 still attached to the delivery system.
• FIGS. 1A and 1B two embodiments of an exemplary vascular prosthesis according to the invention are shown, which differ in a different distal end region, as will be explained below.
• the reference symbols are the same for the corresponding features in both figures, although not all features in FIGS. 1A and 1B have been provided with reference symbols for reasons of clarity.
• 1A and 1B show 10 (FIG. 1A and 100 (FIG. 1B)) as a whole a schematic, not to scale representation of a first embodiment of the vascular prosthesis according to the invention for implantation in a blood vessel of a patient, the vascular prosthesis 10, 100 in the illustration shown in FIGS. 1A and 1B is in the expanded state.
• the vascular prosthesis 10, 100 has a hollow cylindrical base body 11 with a
• Prosthetic material 12 and a stent frame 13 attached thereto which in the embodiment shown in FIG. 1 is a stent frame 13 made up of several stent rings 13a, 13b, 13c, 13d, 13e arranged one behind the other.
• the stent frame 13 can also be in the form of a lasered or braided stent frame, in which cases the stent frame has cells between the braided or lasered stent material.
• the vascular prosthesis 10, 100 in FIGS. 1A and 1B has a proximal 14 and a distal 15 end with a proximal opening 14a and a distal opening 15a, a longitudinal axis L, and an outer side 20 and an inner side 21.
• first terminal stent ring 22 is attached to the outside 20 of the vascular prosthesis 10, 100
• second terminal stent ring 23 is attached to the inside 21 of the vascular prosthesis 10, 100.
• the stent rings 13a to 13e, 22 and 23 have in the one shown in FIGS. 1A and 1B
• the stent rings 13a to 13b, 22 and 23 are fixed to the prosthesis material via seams 27, which are indicated by lines in the figures.
• the prosthesis material and the outermost tips of the pointed arches 24 of the terminal stent springs 22 and 23 which point in the proximal direction include flush so that no pointed arch protrudes freely beyond the prosthesis material 12, and so that the two stent rings 22, 23 are completely covered by the prosthesis material 12.
• the distal end 15 of the vascular prosthesis 10, 100 is designed differently in FIGS. 1A and 1B to the effect that the distal end 15 of the vascular prosthesis 10 shown in FIG. 1A has a terminal stent ring 26 which, with sections of its pointed arches 24 and webs 25 protrude beyond the prosthesis material 12.
• the distal end 15 of the vascular prosthesis 100 shown in FIG. 1B is the distal end
• the end 15 is formed from stent rings 22, 23 completely covered with prosthesis material 12.
• FIG. 1B shows an enlarged section of the proximal end 14 of the vascular prosthesis 10 from FIG. 1A, wherein according to the invention the distal end 15 can also or alternatively have the same design.
• the vascular prosthesis 10 has an outer side 16 which, after implantation, faces a vessel wall, and an inner side 17 which faces the blood flow.
• the vascular prosthesis 10 has two stent rings 18, 19 at the end portion, a first terminal stent ring 18 which is fixed on the outside 16 of the vascular prosthesis 10, and a second terminal stent ring 19 , which is fixed on the inside 17 of the vascular prosthesis 10.
• the two stent rings 18, 19 are fixed to the prosthesis material 12 via seams 20, the seams 20 not distributed over the entire th stent ring 18, 19, but spaced apart from one another at certain intervals and at certain points.
• FIG. 1C an enlarged view of the proximal end 14 of the vascular prostheses 10, 100 is shown.
• first end 31a, 31b is in each case firmly fixed to the prosthesis material 12 via the stent ring 23 attached to the proximal end 14 from the inside 24.
• FIG. 1C For the sake of clarity, only two thread elements 30a, 30b are shown in FIG. 1C; Further thread elements are in principle provided in the embodiment shown in FIG. 1 in order to compress the stent ring 22 and the stent ring 23 as a whole and thus to close the opening 14a of the vascular prosthesis 10, 100.
• the fixation can take place on a web 25 and / or pointed arch 25, for example by means of gluing and / or sewing on the stent ring 22 or 23 and / or on the prosthesis material 12.
• the second end 32 of the thread element 30a has a loop 33.
• the thread element 30a is movably guided in the circumferential direction U alternately over a first web 25a and then under a second web 25b.
• the thread element 30a spans with its length Q essentially three pointed arches 24, two pointed arches 24 pointing proximally p and one pointed arch 24 pointing distal d.
• further thread elements 30 are provided in the circumferential direction U in order to be able to close and open the proximal opening 14a of the vascular prosthesis 10, 100. These each span in the circumferential direction U subsequent pointed arches or webs.
• the thread element 30a is finally passed through at the point 35 in the circumferential direction U of the terminal stent ring 22 between two spaced apart seams 36, 37, whereby a deflection for the thread element 30a is formed.
• the two seams 36, 37 spaced apart from one another can be the same with which the stent ring 22 is also attached to the prosthesis material 21.
• the thread element 30a is guided on the stent ring 22 such that the thread element 30 is at least at this point 35, only very limited to the proximal p and can move distally d, that is, in the area which is delimited by the two seams 36, 37, while on the other hand it can be guided movably in the circumferential direction u.
• the tensile load compresses the portion of the stent ring 22, which is pulled through by the thread element 30a, due to the deflection that is formed by the two seams 36, 37.
• the loop 33a or the second end 32a of the thread element 30a can be pulled out over the proximal end 14 of the vascular prosthesis 10, 100 and, when loaded onto an insertion system (explained below), can be releasably suspended in the loop 33a / to be attached.
• the second (and each further thread element 30) thread element 30b can be guided and provided with a tensile load, so that the stent ring section which is spanned by this thread element 30b can be compressed, so that for complete compression
• the length of the thread elements 30a, 30b also determines their number: the longer the thread elements, the less are necessary to control the opening of the vascular prosthesis opening 14a and also the compression.
• FIG. 2 shows the proximal end 14 of the vascular prostheses shown in FIGS. 1A and 1B in the partially opened or expanded state: the first stent ring 22 and the second stent ring 23 of the vascular prosthesis 10, 100 are partially expanded, the remaining portion of the vascular prosthesis 10, 100 is still kept compressed by a retraction sheath 40 of an insertion system 46 (which is only partially shown in FIG. 2).
• FIG. 2 four thread elements 30a, 30b, 30c, 30d are also shown, which are releasably fastened with their respective second ends 32a, 32b, 32c, 32d in a fixation 42 of a catheter tube 44.
• the opening or expansion of the vascular prosthesis 10, 100 can be controlled as a function of the thread element length Q.
• the second ends 32a, 32b, 32c, 32d of the thread elements 30a, 30b, 30c, 30d released and the vascular prosthesis 10, 100 can develop in a self-expanding manner.
• the thread elements 30a, 30b, 30c, 30d are again guided over the respective deflection around the circumference of the vascular prosthesis 10, 100 and placed in the blood vessel between the vascular prosthesis 10, 100 and the vessel wall.
• vascular prosthesis 10 For loading the vascular prosthesis 10, 100 onto an insertion system 46, it is kept compressed on a catheter tube 44 by a retraction sheath 40 about its longitudinal axis.
• the proximal end 14 (or the distal end 15) or the proximal opening 14a (distal opening 15a) of the vascular prosthesis 10, 100 is additionally closed by means of tensile load via the thread elements 30a, 30b, 30c, 30d by the second ends 32a , 32b, 32c, 32d of the thread elements 30a, 30b, 30c, 30d are hung into the fixation 42 via the loops 33 thereof.
• the fixation shown in Fig. 2 is a system of several, preferably the number of thread elements corresponding elongated fixing rods, which are axially displaceable in the catheter tube. Alternatively, several thread elements can also be mounted using a fixing rod. Details for an exemplary insertion system with a fixation as described herein are disclosed, for example, in EP 1 920739, the content of which in this regard is hereby made the subject matter in full.
• the vascular prosthesis 10, 100 loaded onto the catheter tube 44 and held compressed by a retraction sheath 40 is introduced into a blood vessel of a patient, after which the retraction sheath is correctly positioned
• the main part of the vascular prosthesis 10, 100 has been released, the proximal (or the distal) end being fixed and compressed and the corresponding opening of the vascular prosthesis thus remaining closed. In this way, repositioning of the vascular prosthesis can easily be effected, should this be necessary, without the blood vessel being injured at this point.
• the axial fixation is shifted to relieve the thread elements 30a, 30b, 30c, 30d, whereby the on the thread elements 30a, 30b, 30c, 30d exerted tension can be specifically and - if desired - gradually relieved, so that the opening 14a, 15a of the vascular prosthesis 10, 100 can also be opened gradually. If the second ends of the thread elements 30a, 30b, 30c, 30d are completely released from the fixation, the proximal / distal end 14, 15 of the Gefäßpro thesis 10, 100 is completely opened.

Landscapes

• Health & Medical Sciences (AREA)
• Engineering & Computer Science (AREA)
• Biomedical Technology (AREA)
• Cardiology (AREA)
• Oral & Maxillofacial Surgery (AREA)
• Transplantation (AREA)
• Heart & Thoracic Surgery (AREA)
• Vascular Medicine (AREA)
• Life Sciences & Earth Sciences (AREA)
• Animal Behavior & Ethology (AREA)
• General Health & Medical Sciences (AREA)
• Public Health (AREA)
• Veterinary Medicine (AREA)
• Gastroenterology & Hepatology (AREA)
• Pulmonology (AREA)
• Prostheses (AREA)
• Media Introduction/Drainage Providing Device (AREA)

Applications Claiming Priority (2)

Publications (1)

Family

ID=72046864

Family Applications (1)

Country Status (7)

Family Cites Families (18)

• 2019
  • 2019-08-14 DE DE102019121930.2A patent/DE102019121930A1/de active Pending
• 2020
  • 2020-08-05 JP JP2022508999A patent/JP2022544399A/ja active Pending
  • 2020-08-05 BR BR112022002702A patent/BR112022002702A2/pt unknown
  • 2020-08-05 CN CN202080057458.4A patent/CN114269288A/zh active Pending
  • 2020-08-05 EP EP20754198.8A patent/EP4013349A1/de active Pending
  • 2020-08-05 WO PCT/EP2020/071974 patent/WO2021028286A1/de unknown
• 2022
  • 2022-02-07 US US17/665,804 patent/US20220151763A1/en active Pending

Also Published As

Similar Documents

Legal Events