EP3946392A4 - Probiotic biofilm compositions and methods of preparing same - Google Patents

Probiotic biofilm compositions and methods of preparing same Download PDF

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Publication number
EP3946392A4
EP3946392A4 EP20776481.2A EP20776481A EP3946392A4 EP 3946392 A4 EP3946392 A4 EP 3946392A4 EP 20776481 A EP20776481 A EP 20776481A EP 3946392 A4 EP3946392 A4 EP 3946392A4
Authority
EP
European Patent Office
Prior art keywords
preparing
methods
biofilm compositions
probiotic biofilm
probiotic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP20776481.2A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP3946392A1 (en
Inventor
Hila ELIYAHU
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mybiotics Pharma Ltd
Original Assignee
Mybiotics Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US16/368,030 external-priority patent/US10709744B1/en
Application filed by Mybiotics Pharma Ltd filed Critical Mybiotics Pharma Ltd
Publication of EP3946392A1 publication Critical patent/EP3946392A1/en
Publication of EP3946392A4 publication Critical patent/EP3946392A4/en
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745—Bifidobacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225—Lactobacillus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gynecology & Obstetrics (AREA)
  • Oncology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
EP20776481.2A 2019-03-28 2020-03-29 Probiotic biofilm compositions and methods of preparing same Withdrawn EP3946392A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16/368,030 US10709744B1 (en) 2019-03-28 2019-03-28 Probiotic biofilm suppositories
US201962827931P 2019-04-02 2019-04-02
PCT/IL2020/050380 WO2020194319A1 (en) 2019-03-28 2020-03-29 Probiotic biofilm compositions and methods of preparing same

Publications (2)

Publication Number Publication Date
EP3946392A1 EP3946392A1 (en) 2022-02-09
EP3946392A4 true EP3946392A4 (en) 2022-12-07

Family

ID=72610340

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20776481.2A Withdrawn EP3946392A4 (en) 2019-03-28 2020-03-29 Probiotic biofilm compositions and methods of preparing same

Country Status (11)

Country Link
EP (1) EP3946392A4 (cg-RX-API-DMAC10.html)
JP (1) JP2022535323A (cg-RX-API-DMAC10.html)
KR (1) KR20220016042A (cg-RX-API-DMAC10.html)
CN (1) CN113766923A (cg-RX-API-DMAC10.html)
AU (1) AU2020250170A1 (cg-RX-API-DMAC10.html)
BR (1) BR112021019437A2 (cg-RX-API-DMAC10.html)
CA (1) CA3131165A1 (cg-RX-API-DMAC10.html)
IL (1) IL286704A (cg-RX-API-DMAC10.html)
MX (1) MX2021011628A (cg-RX-API-DMAC10.html)
SG (1) SG11202110741YA (cg-RX-API-DMAC10.html)
WO (1) WO2020194319A1 (cg-RX-API-DMAC10.html)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2025532188A (ja) * 2021-09-27 2025-09-29 マイバイオティクス ファーマ リミテッド 微生物組成物、その調製方法およびその使用
CA3247168A1 (en) * 2022-04-05 2023-10-12 Mybiotics Pharma Ltd. BACTERIAL COMPOSITIONS AND METHODS OF CULTURE BACTERIA ON PARTICLES

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009092810A2 (en) * 2008-01-24 2009-07-30 Bacterfield Oü Single pharmaceutical composition containing antibiotics and probiotics
US20120247993A1 (en) * 2008-11-14 2012-10-04 Unistraw Patent Holdings Limited Probiotic Compositions, Methods and Apparatus for Their Administration
US20140370107A1 (en) * 2012-02-01 2014-12-18 Probiotical North America Inc. Multilayer microincapuslated probiotic bacteria
WO2017095968A1 (en) * 2015-11-30 2017-06-08 Imagilin Technology Llc Compositions comprising probiotics and methods of use thereof
US20170173091A1 (en) * 2015-11-10 2017-06-22 Probiotech Llc Probiotic delivery systems
WO2017208237A1 (en) * 2016-05-29 2017-12-07 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Method of generating bacterial compositions

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1776877A1 (en) * 2005-10-21 2007-04-25 N.V. Nutricia Method for stimulating the intestinal flora
IT1400821B1 (it) * 2009-03-09 2013-07-02 Probiotical Spa Sospensione oleosa contenente batteri probiotici per uso pediatrico
EP3536168A3 (en) * 2014-03-06 2019-10-16 The Research Institute at Nationwide Children's Hospital Probiotic formulations and methods for use
CN106232578B (zh) * 2014-03-28 2019-06-07 帝斯曼知识产权资产管理有限公司 从生产类胡萝卜素的生物有机体分离类胡萝卜素的方法
CA2985729C (en) * 2015-05-11 2023-05-09 Mybiotics Pharma Ltd Systems and methods for growing a biofilm of probiotic bacteria on solid particles for colonization of bacteria in the gut
KR101784847B1 (ko) * 2016-05-10 2017-10-13 주식회사 하우동천 질염 예방 및 치료용 유산균 함유 조성물 및 이의 용도
KR102380134B1 (ko) * 2016-05-25 2022-03-29 마이바이오틱스 파마 엘티디. 미생물총 치료를 위한 조성물 및 방법
WO2018013583A2 (en) * 2016-07-11 2018-01-18 The Brigham And Women's Hospital, Inc. Medicinal vaginal lactobacillus cocktail
EP3388069B1 (en) * 2017-04-12 2019-05-01 ETH Zurich Consortia of living bacteria useful for treatment of microbiome dysbiosis
WO2019136391A1 (en) * 2018-01-05 2019-07-11 Human Longevity, Inc. Probiotic compositions comprising bacteria from bacteroids and firmicutes phyla

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009092810A2 (en) * 2008-01-24 2009-07-30 Bacterfield Oü Single pharmaceutical composition containing antibiotics and probiotics
US20120247993A1 (en) * 2008-11-14 2012-10-04 Unistraw Patent Holdings Limited Probiotic Compositions, Methods and Apparatus for Their Administration
US20140370107A1 (en) * 2012-02-01 2014-12-18 Probiotical North America Inc. Multilayer microincapuslated probiotic bacteria
US20170173091A1 (en) * 2015-11-10 2017-06-22 Probiotech Llc Probiotic delivery systems
WO2017095968A1 (en) * 2015-11-30 2017-06-08 Imagilin Technology Llc Compositions comprising probiotics and methods of use thereof
WO2017208237A1 (en) * 2016-05-29 2017-12-07 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Method of generating bacterial compositions

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2020194319A1 *

Also Published As

Publication number Publication date
MX2021011628A (es) 2021-12-10
CA3131165A1 (en) 2020-10-01
WO2020194319A1 (en) 2020-10-01
KR20220016042A (ko) 2022-02-08
CN113766923A (zh) 2021-12-07
EP3946392A1 (en) 2022-02-09
JP2022535323A (ja) 2022-08-08
BR112021019437A2 (pt) 2021-11-30
IL286704A (en) 2021-10-31
AU2020250170A1 (en) 2021-10-28
SG11202110741YA (en) 2021-10-28

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