EP3946392A4 - Probiotic biofilm compositions and methods of preparing same - Google Patents

Probiotic biofilm compositions and methods of preparing same Download PDF

Info

Publication number
EP3946392A4
EP3946392A4 EP20776481.2A EP20776481A EP3946392A4 EP 3946392 A4 EP3946392 A4 EP 3946392A4 EP 20776481 A EP20776481 A EP 20776481A EP 3946392 A4 EP3946392 A4 EP 3946392A4
Authority
EP
European Patent Office
Prior art keywords
methods
preparing same
biofilm compositions
probiotic biofilm
probiotic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP20776481.2A
Other languages
German (de)
French (fr)
Other versions
EP3946392A1 (en
Inventor
Hila ELIYAHU
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mybiotics Pharma Ltd
Original Assignee
Mybiotics Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US16/368,030 external-priority patent/US10709744B1/en
Application filed by Mybiotics Pharma Ltd filed Critical Mybiotics Pharma Ltd
Publication of EP3946392A1 publication Critical patent/EP3946392A1/en
Publication of EP3946392A4 publication Critical patent/EP3946392A4/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745—Bifidobacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225—Lactobacillus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP20776481.2A 2019-03-28 2020-03-29 Probiotic biofilm compositions and methods of preparing same Pending EP3946392A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16/368,030 US10709744B1 (en) 2019-03-28 2019-03-28 Probiotic biofilm suppositories
US201962827931P 2019-04-02 2019-04-02
PCT/IL2020/050380 WO2020194319A1 (en) 2019-03-28 2020-03-29 Probiotic biofilm compositions and methods of preparing same

Publications (2)

Publication Number Publication Date
EP3946392A1 EP3946392A1 (en) 2022-02-09
EP3946392A4 true EP3946392A4 (en) 2022-12-07

Family

ID=72610340

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20776481.2A Pending EP3946392A4 (en) 2019-03-28 2020-03-29 Probiotic biofilm compositions and methods of preparing same

Country Status (11)

Country Link
EP (1) EP3946392A4 (en)
JP (1) JP2022535323A (en)
KR (1) KR20220016042A (en)
CN (1) CN113766923A (en)
AU (1) AU2020250170A1 (en)
BR (1) BR112021019437A2 (en)
CA (1) CA3131165A1 (en)
IL (1) IL286704A (en)
MX (1) MX2021011628A (en)
SG (1) SG11202110741YA (en)
WO (1) WO2020194319A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023195008A1 (en) * 2022-04-05 2023-10-12 Mybiotics Pharma Ltd. Bacterial compositions and methods for growing bacteria on particles

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009092810A2 (en) * 2008-01-24 2009-07-30 Bacterfield Oü Single pharmaceutical composition containing antibiotics and probiotics
US20120247993A1 (en) * 2008-11-14 2012-10-04 Unistraw Patent Holdings Limited Probiotic Compositions, Methods and Apparatus for Their Administration
US20140370107A1 (en) * 2012-02-01 2014-12-18 Probiotical North America Inc. Multilayer microincapuslated probiotic bacteria
WO2017095968A1 (en) * 2015-11-30 2017-06-08 Imagilin Technology Llc Compositions comprising probiotics and methods of use thereof
US20170173091A1 (en) * 2015-11-10 2017-06-22 Probiotech Llc Probiotic delivery systems
WO2017208237A1 (en) * 2016-05-29 2017-12-07 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Method of generating bacterial compositions

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1776877A1 (en) * 2005-10-21 2007-04-25 N.V. Nutricia Method for stimulating the intestinal flora
IT1400821B1 (en) * 2009-03-09 2013-07-02 Probiotical Spa OIL SUSPENSION CONTAINING PROBIOTIC BACTERIA FOR PEDIATRIC USE
JP6754694B2 (en) * 2014-03-06 2020-09-16 リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル Probiotic formulations and methods for use
US10793847B2 (en) * 2015-05-11 2020-10-06 Mybiotics Pharma Ltd. Systems and methods for growing a biofilm of probiotic bacteria on solid particles for colonization of bacteria in the gut
KR101784847B1 (en) * 2016-05-10 2017-10-13 주식회사 하우동천 A composition comprising lactic acid bacteria for protecting and treating vaginosis disease and the use thereof
WO2018013583A2 (en) * 2016-07-11 2018-01-18 The Brigham And Women's Hospital, Inc. Medicinal vaginal lactobacillus cocktail
US20190209626A1 (en) * 2018-01-05 2019-07-11 Human Longevity, Inc. Probiotic compositions comprising bacteria from bacteroids and firmicutes phyla

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009092810A2 (en) * 2008-01-24 2009-07-30 Bacterfield Oü Single pharmaceutical composition containing antibiotics and probiotics
US20120247993A1 (en) * 2008-11-14 2012-10-04 Unistraw Patent Holdings Limited Probiotic Compositions, Methods and Apparatus for Their Administration
US20140370107A1 (en) * 2012-02-01 2014-12-18 Probiotical North America Inc. Multilayer microincapuslated probiotic bacteria
US20170173091A1 (en) * 2015-11-10 2017-06-22 Probiotech Llc Probiotic delivery systems
WO2017095968A1 (en) * 2015-11-30 2017-06-08 Imagilin Technology Llc Compositions comprising probiotics and methods of use thereof
WO2017208237A1 (en) * 2016-05-29 2017-12-07 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Method of generating bacterial compositions

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2020194319A1 *

Also Published As

Publication number Publication date
JP2022535323A (en) 2022-08-08
WO2020194319A1 (en) 2020-10-01
IL286704A (en) 2021-10-31
SG11202110741YA (en) 2021-10-28
MX2021011628A (en) 2021-12-10
CA3131165A1 (en) 2020-10-01
BR112021019437A2 (en) 2021-11-30
KR20220016042A (en) 2022-02-08
CN113766923A (en) 2021-12-07
EP3946392A1 (en) 2022-02-09
AU2020250170A1 (en) 2021-10-28

Similar Documents

Publication Publication Date Title
EP4022059A4 (en) Oligonucleotide compositions and methods of use thereof
EP3959318A4 (en) Oligonucleotide compositions and methods of use thereof
EP3965780A4 (en) Oligonucleotide compositions and methods of use thereof
EP4037695A4 (en) Oligonucleotide compositions and methods of use thereof
EP3775203A4 (en) Oligonucleotide compositions and methods of use thereof
EP3790596A4 (en) Oligonucleotide compositions and methods of use thereof
EP3990562A4 (en) Adhesive compositions and methods of making the same
EP3997115A4 (en) Il-2 compositions and methods of use thereof
EP3976638A4 (en) Il-2 compositions and methods of use thereof
EP3893917A4 (en) Il-15 compositions and methods of use thereof
EP3761972A4 (en) Bioreactive compositions and methods of use thereof
EP4081231A4 (en) Compositions comprising microbes and methods of use and making thereof
EP3856214A4 (en) Microbial compositions and methods of use
EP3829307A4 (en) Bismuth-thiol compositions and methods of use
EP3976070A4 (en) Shaped organoid compositions and methods of making same
EP3731833A4 (en) Compositions containing thymohydroquinone and their method of preparation
EP4034605A4 (en) Polishing compositions and methods of use thereof
EP3606493A4 (en) Dental cement compositions and methods of use
EP4003443A4 (en) Hydratable and flowable implantable compositions and methods of making and using them
EP4045226A4 (en) Polishing compositions and methods of use thereof
EP4142740A4 (en) Compositions and methods of use thereof
EP3840769A4 (en) Cyclosporine compositions and methods of use
EP3843555A4 (en) Anthocyanin-based colorant compositions and methods of use thereof
EP3836938A4 (en) Solid forms of substituted benzoxaborole and compositions thereof
EP4081047A4 (en) Enzyme compositions and methods of making them

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20211028

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20221104

RIC1 Information provided on ipc code assigned before grant

Ipc: C12R 1/225 20060101ALI20221028BHEP

Ipc: C12R 1/01 20060101ALI20221028BHEP

Ipc: C12N 1/20 20060101ALI20221028BHEP

Ipc: A61P 1/00 20060101ALI20221028BHEP

Ipc: A61K 35/745 20150101ALI20221028BHEP

Ipc: A61K 35/747 20150101ALI20221028BHEP

Ipc: A61K 35/741 20150101AFI20221028BHEP