CA3131165A1 - Probiotic biofilm compositions and methods of preparing same - Google Patents

Probiotic biofilm compositions and methods of preparing same Download PDF

Info

Publication number
CA3131165A1
CA3131165A1 CA3131165A CA3131165A CA3131165A1 CA 3131165 A1 CA3131165 A1 CA 3131165A1 CA 3131165 A CA3131165 A CA 3131165A CA 3131165 A CA3131165 A CA 3131165A CA 3131165 A1 CA3131165 A1 CA 3131165A1
Authority
CA
Canada
Prior art keywords
bacteria
biofilm
composition
growth
particle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3131165A
Other languages
English (en)
French (fr)
Inventor
David Daboush
Dorit ROZNER
Stephanie Cohen
Hila ELYAHU
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mybiotics Pharma Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US16/368,030 external-priority patent/US10709744B1/en
Application filed by Individual filed Critical Individual
Publication of CA3131165A1 publication Critical patent/CA3131165A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745—Bifidobacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225—Lactobacillus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gynecology & Obstetrics (AREA)
  • Oncology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
CA3131165A 2019-03-28 2020-03-29 Probiotic biofilm compositions and methods of preparing same Pending CA3131165A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US16/368,030 US10709744B1 (en) 2019-03-28 2019-03-28 Probiotic biofilm suppositories
US16/368,030 2019-03-28
US201962827931P 2019-04-02 2019-04-02
US62/827,931 2019-04-02
PCT/IL2020/050380 WO2020194319A1 (en) 2019-03-28 2020-03-29 Probiotic biofilm compositions and methods of preparing same

Publications (1)

Publication Number Publication Date
CA3131165A1 true CA3131165A1 (en) 2020-10-01

Family

ID=72610340

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3131165A Pending CA3131165A1 (en) 2019-03-28 2020-03-29 Probiotic biofilm compositions and methods of preparing same

Country Status (11)

Country Link
EP (1) EP3946392A4 (cg-RX-API-DMAC10.html)
JP (1) JP2022535323A (cg-RX-API-DMAC10.html)
KR (1) KR20220016042A (cg-RX-API-DMAC10.html)
CN (1) CN113766923A (cg-RX-API-DMAC10.html)
AU (1) AU2020250170A1 (cg-RX-API-DMAC10.html)
BR (1) BR112021019437A2 (cg-RX-API-DMAC10.html)
CA (1) CA3131165A1 (cg-RX-API-DMAC10.html)
IL (1) IL286704A (cg-RX-API-DMAC10.html)
MX (1) MX2021011628A (cg-RX-API-DMAC10.html)
SG (1) SG11202110741YA (cg-RX-API-DMAC10.html)
WO (1) WO2020194319A1 (cg-RX-API-DMAC10.html)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2025532188A (ja) * 2021-09-27 2025-09-29 マイバイオティクス ファーマ リミテッド 微生物組成物、その調製方法およびその使用
CA3247168A1 (en) * 2022-04-05 2023-10-12 Mybiotics Pharma Ltd. BACTERIAL COMPOSITIONS AND METHODS OF CULTURE BACTERIA ON PARTICLES

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1776877A1 (en) * 2005-10-21 2007-04-25 N.V. Nutricia Method for stimulating the intestinal flora
WO2009092810A2 (en) * 2008-01-24 2009-07-30 Bacterfield Oü Single pharmaceutical composition containing antibiotics and probiotics
DE09825657T1 (de) * 2008-11-14 2014-03-13 Unistraw Holdings Pte Ltd. Probiotische Zusammensetzungen, Verfahren und Vorrichtung zu ihrer Verabreichung
IT1400821B1 (it) * 2009-03-09 2013-07-02 Probiotical Spa Sospensione oleosa contenente batteri probiotici per uso pediatrico
ITMI20120131A1 (it) * 2012-02-01 2013-08-02 Probiotical Spa Batteri probiotici microincapsulati multistrato, loro produzione ed uso
EP3536168A3 (en) * 2014-03-06 2019-10-16 The Research Institute at Nationwide Children's Hospital Probiotic formulations and methods for use
CN106232578B (zh) * 2014-03-28 2019-06-07 帝斯曼知识产权资产管理有限公司 从生产类胡萝卜素的生物有机体分离类胡萝卜素的方法
CA2985729C (en) * 2015-05-11 2023-05-09 Mybiotics Pharma Ltd Systems and methods for growing a biofilm of probiotic bacteria on solid particles for colonization of bacteria in the gut
AU2016353091B2 (en) * 2015-11-10 2022-07-14 Probiotech Llc Probiotic delivery systems
WO2017095968A1 (en) * 2015-11-30 2017-06-08 Imagilin Technology Llc Compositions comprising probiotics and methods of use thereof
KR101784847B1 (ko) * 2016-05-10 2017-10-13 주식회사 하우동천 질염 예방 및 치료용 유산균 함유 조성물 및 이의 용도
KR102380134B1 (ko) * 2016-05-25 2022-03-29 마이바이오틱스 파마 엘티디. 미생물총 치료를 위한 조성물 및 방법
US11297868B2 (en) * 2016-05-29 2022-04-12 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Method of generating bacterial compositions
WO2018013583A2 (en) * 2016-07-11 2018-01-18 The Brigham And Women's Hospital, Inc. Medicinal vaginal lactobacillus cocktail
EP3388069B1 (en) * 2017-04-12 2019-05-01 ETH Zurich Consortia of living bacteria useful for treatment of microbiome dysbiosis
WO2019136391A1 (en) * 2018-01-05 2019-07-11 Human Longevity, Inc. Probiotic compositions comprising bacteria from bacteroids and firmicutes phyla

Also Published As

Publication number Publication date
MX2021011628A (es) 2021-12-10
EP3946392A4 (en) 2022-12-07
WO2020194319A1 (en) 2020-10-01
KR20220016042A (ko) 2022-02-08
CN113766923A (zh) 2021-12-07
EP3946392A1 (en) 2022-02-09
JP2022535323A (ja) 2022-08-08
BR112021019437A2 (pt) 2021-11-30
IL286704A (en) 2021-10-31
AU2020250170A1 (en) 2021-10-28
SG11202110741YA (en) 2021-10-28

Similar Documents

Publication Publication Date Title
US12364276B2 (en) Probiotic for inhibiting growth of Proteus mirabilis, and fermentation broth and application thereof
US12036252B2 (en) Pairing probiotics and prebiotics, methods for growth and use, separately and in combination
Hongpattarakere et al. In vitro prebiotic evaluation of exopolysaccharides produced by marine isolated lactic acid bacteria
US20150190438A1 (en) Novel strain of lactobacillus crispatus
CN111088178A (zh) 一种产乳酸和h2o2的乳杆菌及其应用
Mazhar et al. In vitro safety and functional characterization of the novel Bacillus coagulans strain CGI314
Thakur et al. Invitro study of riboflavin producing lactobacilli as potential probiotic
CN101603021B (zh) 代谢活性微生物及其生产方法
Nakkarach et al. Comparison of synbiotic beverages produced from riceberry malt extract using selected free and encapsulated probiotic lactic acid bacteria
VidyaLaxme et al. Synergistic effects of probiotic Leuconostoc mesenteroides and Bacillus subtilis in malted ragi (Eleucine corocana) food for antagonistic activity against V. cholerae and other beneficial properties
JP2019189620A (ja) 組成物
KR102048690B1 (ko) 안정성이 증진된 유산균 및 이의 제조방법
Suomalainen et al. In vitro and in vivo gastrointestinal survival, antibiotic susceptibility and genetic identification of Propionibacterium freudenreichii ssp. shermanii JS
WO2025102814A1 (zh) 一种短双歧杆菌vb316及其应用
WO2020194319A1 (en) Probiotic biofilm compositions and methods of preparing same
US20200338137A1 (en) Probiotic biofilm suppositories
US10709744B1 (en) Probiotic biofilm suppositories
US20220154134A1 (en) Probiotic biofilm compositions and methods of preparing same
Asan-Ozusaglam et al. A new probiotic candidate bacterium from human milk: Limosilactobacillus vaginalis MA-10
CN116649579A (zh) 一种缓解孤独症胃肠道的益生菌组合物及其制备方法和用途
US20250270536A1 (en) Bacterial compositions and methods for growing bacteria on particles
Pham et al. Cholesterol-lowering potential and exopolysaccharide biosynthesis of Lactobacillus spp. isolated from human milk
Sirilun et al. Functional properties of β-glucosidase-producing Lactobacillus plantarum SC 359 isolated from Thai fermented soybean food
Ying et al. In Vitro antibacterial activity of Lactiplantibacillus sp. cell-free supernatants against Porphyromonas gingivalis: A potential approach for oral health
KR20250000036A (ko) 비타민 b9을 생성하는 신규한 한국인 유래 균주 락토코커스 락티스 pl186와 이를 유효성분으로 포함하는 건강기능식품 조성물

Legal Events

Date Code Title Description
B12 Application deemed to be withdrawn, abandoned or lapsed

Free format text: ST27 STATUS EVENT CODE: N-6-6-B10-B12-B301 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: DEEMED ABANDONED - FAILURE TO RESPOND TO A REQUEST FOR EXAMINATION NOTICE

Effective date: 20240715

W00 Other event occurred

Free format text: ST27 STATUS EVENT CODE: A-1-1-W10-W00-W100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: LETTER SENT

Effective date: 20250915

U13 Renewal or maintenance fee not paid

Free format text: ST27 STATUS EVENT CODE: N-1-6-U10-U13-U300 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: DEEMED ABANDONED - FAILURE TO RESPOND TO MAINTENANCE FEE NOTICE

Effective date: 20251117

W00 Other event occurred

Free format text: ST27 STATUS EVENT CODE: N-6-6-W10-W00-W100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: LETTER SENT

Effective date: 20251229

W00 Other event occurred

Free format text: ST27 STATUS EVENT CODE: N-6-6-W10-W00-W100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: LETTER SENT

Effective date: 20260511

W00 Other event occurred

Free format text: ST27 STATUS EVENT CODE: N-6-6-W10-W00-W100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: LETTER SENT

Effective date: 20260703