EP3793509A1 - Procédé de réduction de sueur à l'acide malonique - Google Patents

Procédé de réduction de sueur à l'acide malonique

Info

Publication number
EP3793509A1
EP3793509A1 EP19719179.4A EP19719179A EP3793509A1 EP 3793509 A1 EP3793509 A1 EP 3793509A1 EP 19719179 A EP19719179 A EP 19719179A EP 3793509 A1 EP3793509 A1 EP 3793509A1
Authority
EP
European Patent Office
Prior art keywords
preparation
cas
kit
part preparation
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19719179.4A
Other languages
German (de)
English (en)
Inventor
Frank Lehmbeck
Robert Klauck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beiersdorf AG
Original Assignee
Beiersdorf AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beiersdorf AG filed Critical Beiersdorf AG
Publication of EP3793509A1 publication Critical patent/EP3793509A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/362—Polycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/25—Silicon; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00—Anti-perspirants or body deodorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/30—Characterized by the absence of a particular group of ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/88—Two- or multipart kits
    • A61K2800/882—Mixing prior to application

Definitions

  • the present invention relates to a method for reducing or preventing the formation of perspiration by application of two cosmetic part preparations, characterized in that the period between mixing of the part preparations and
  • Application of the mixture to the skin is not more than five minutes, and wherein the first part preparation comprises an alkali metal silicate and the second part preparation contains malonic acid.
  • Sweat is an aqueous secretion secreted by the skin of the human through the so-called sweat glands.
  • sweat glands There are three types of sweat glands in the skin, namely apocrine, eccrine, and apoekrine sweat glands (Int J Cosmet Sei. 2007 Jun; 29 (3): 169-79).
  • the eccrine sweat glands in humans are distributed practically throughout the body and can produce significant amounts of a clear, odorless secretion that is over 99% water.
  • the apocrine sweat glands come only in the hairy body areas of the armpit and genital region and the
  • Cosmetic antiperspirants or deodorants / deodorants serve to
  • Body odor arises when the per se odorless fresh sweat by microorganisms such.
  • Staphylococci and Corynebacteria is decomposed.
  • German-speaking countries - products for use in the armpit area as a whole German-speaking countries - products for use in the armpit area as a whole
  • Antiperspirants are antiperspirants that - in contrast to the
  • Deodorants which generally prevent microbial decomposition of already formed sweat - to prevent the secretion of sweat at all.
  • the classic antiperspirants used are, in particular, aluminum salts or aluminum / zirconium salts. These inhibit the flow of sweat by obstructing the excretory ducts of the sweat glands by precipitating them together with the skin's own proteins and thus leading to so-called plugs. Therefore, there may be a congestion of sweat within the gland.
  • a disadvantage of the aluminum salts used hitherto for sweat inhibition is the currently not yet fully understood long-term toxicity.
  • Aluminum has long been suspected of promoting or inducing neurodegenerative diseases such as dementia, particularly Alzheimer's disease. Also, aluminum is associated with the onset of breast cancer
  • alkaline silicates as an antiperspirant active ingredient is known.
  • the disclosed preparations contain, in addition to the alkaline silicates
  • Citric acid phytic acid or maleic acid.
  • DE 102015226630 A1 discloses a method of reducing or preventing the development of apothecary sweat by applying a mixture of two cosmetic part preparations, characterized in that the time between mixing of the part preparations and application of the mixture to the skin is not more than five minutes and wherein one Part preparation one or more silicates (1st phase) and the second part preparation contains one or more pH regulators.
  • the pH regulators are selected from a group of buffer systems which according to the
  • DE 102015226630 A1 does not disclose the use of malonic acid. Furthermore, DE 102015226630 A1 still FR 2977151 indicate that certain acids can further increase the antiperspirant activity of the alkaline silicates.
  • the invention is therefore a method for reducing or preventing the
  • the invention is also a cosmetic product having a
  • Two-chamber container suitable for the application of cosmetic preparations characterized in that a chamber contains a first part preparation containing at least one alkali metal silicate, and the second chamber contains a second part preparation containing malonic acid, wherein in the application, the contents of the first and second chambers simultaneously be taken from the chambers and the first and second
  • the invention also relates to a kit comprising at least two cosmetic
  • Partial preparations wherein a first part preparation comprises at least one alkali metal silicate and a second part preparation at least malonic acid.
  • the first and second part preparation are stored separately in two different chambers and for The time between mixing of the partial preparations and application of the mixture to the skin is preferably not more than five minutes.
  • Another object of the present invention is also the use of the product according to the invention for reducing or preventing the formation of perspiration, characterized in that the mixture of the first and second part of the preparation is applied to the skin within 5 minutes after mixing.
  • part preparations or mixtures are mentioned, they are in any case cosmetic preparations or mixtures.
  • the silicon compounds continue to be present as silicates.
  • silicic acids it is also possible for silicic acids to be present.
  • the mixtures prepared by this process are only stable for a short time, which is why it is necessary to use this AT formulation directly after mixing. If the mixture is not fast enough or the application is too late, then it may lead to a polymerization of the silica (gelation). The resulting gel has no sweat-reducing effect when applied to the skin.
  • the antiperspirant effect is the possibility of reducing or preventing the formation of perspiration or a reduction in Switzerland. That the mixtures obtained according to the invention act as a sweat inhibitor and reduce perspiration. As a result of this effect, a reduction of the distinctive odor of sweat also takes place indirectly.
  • the mixture of the first part preparation and the second part preparation is applied from a multichamber container, wherein a first chamber of the multichamber container contains the first part preparation and a second chamber of the multichamber container contains the second part preparation.
  • the first part preparation contains at least one alkali metal silicate, preferably sodium silicate and / or potassium silicate, with sodium silicate being particularly preferred.
  • the first part preparation advantageously contains water in addition to the alkali metal silicates according to the invention.
  • alkali metal silicates is given and calculated in accordance with the invention as described above as the content of S1O2, since the silicon is not uniform
  • the Si0 2 content can be determined gravimetrically very easily, eg by ashing.
  • alkali metal silicates in particular sodium silicate
  • sodium silicate can be obtained commercially either in solid, crystalline form or already as an aqueous solution.
  • Alkaline-aqueous solutions of sodium silicate are commercially available from Honeywell under product number 338443 (sodium silicate solution, reagent grade). This watery
  • Sodium silicate solution has a Si0 2 content of 26.5 wt .-%, based on the
  • the first part preparation according to the invention advantageously has a pH of> 10, preferably> 10.5, more preferably> 11 and especially preferably> 1.5.
  • the second part preparation contains malonic acid. Besides malonic acid, other acids may advantageously be present in the second part preparation. However, it has been shown that a particularly efficient sweat reduction takes place when the second
  • Part preparation in addition to malonic acid further acids only in a proportion of up to 0.5% by weight based on the total weight of the second part preparation. It is accordingly preferred if the second part preparation in addition to malonic acid contains further acids only in a proportion of up to 0.5 wt .-% based on the total weight of the second part of the preparation or no other acids.
  • Buffer system of bases and acids wherein the acid is at least the malonic acid contained in the second part of the preparation.
  • the buffer systems may be bases, advantageously selected from the group consisting of 2-aminobutanol, 2- (2-aminoethoxy) ethanol, aminoethyl propanediol, aminomethyl propanediol, aminomethyl propanol, aminopropanediol, bis-hydroxyethyl tromethamine, butyl diethanolamine, butyl ethanolamine, dibutyl ethanolamine, diethanolamine, diethyl ethanolamines,
  • Diisopropanolamines dimethylamino methylpropanol, dimethyl isopropanolamines, dimethyl MEA, ethanolamines, ethyl ethanolamines, isopropanolamines, methyl diethanolamines, methylethanolamines, triethanolamines, triisopropanolamines, tromethamines,
  • Polyethyleneimines tetrahydroxypropyl ethylenediamine and / or ammonia.
  • the second part preparation has a pH in the range from a pH of 1.5 to 5, preferably 2 to 4 and particularly preferably 2.5 to 3.
  • the proportion of malonic acid in the second part preparation is advantageously from 2.5% by weight to 12% by weight, preferably from 3.5% by weight to 9% by weight and particularly preferably from 5% by weight to 8 wt .-%, each based on the total weight of the second part preparation.
  • Advantageous embodiments of the invention are characterized in that the mixing ratio of the first part preparation to the second part preparation based on their weight fractions 10: 1 to 1: 10, preferably 5: 1 to 1: 5, more preferably 2: 1 to 1: 2 and particularly preferred 1, 2: 1 to 1: 1, 2. If these proportions by weight of the two partial preparations are used, a light and uniform mixing of the partial preparations takes place. A temporally uniform polymerization / gel formation within all subregions of the mixture produced is thus ensured. This avoids that the gelation in some parts of the mixture is faster or slower than in other areas. As a result, uniform sweat reduction is achieved when the mixture is applied to a larger area of the skin. It avoids being in Some skin areas achieve a better or worse sweat reduction than in other skin areas.
  • advantageous embodiments of the invention are characterized in that the proportions of the alkali metal silicates in the first part preparation and the proportions of the acids, in particular of the malonic acid, and the optionally contained bases in the second
  • Partial preparation are selected so that the mixture of the first and second part of the preparation has a pH between 3.5 and 8, preferably between 4 and 5.7 and more preferably between 4.3 and 5.3.
  • the proportion of S1O2 of the general formula M2O X is S1O2 -y ⁇ O, where M is an alkali metal, x is 1 and y is 0 to 9, advantageously 0.5 to 8 wt .-%, preferably 1 wt .-% to 6 wt .-% and particularly preferably, 2 wt .-% to 5 wt .-% based on the total weight of the mixture of the first and second part of the preparation.
  • the mixture of the first part preparation and the second part preparation is advantageously carried out an adjustment of the pH of the resulting mixture to a pH between 3.5 and 8, preferably between 4 and 5.7 and more preferably between 4.3 and 5.3.
  • first part preparation and the second part preparation may contain further ingredients customary for cosmetic preparations, such as perfume, rheology modifiers, solubilizers, conditioners, dyes, skin care components.
  • one or both of the part preparations contain stabilizers which are the
  • group A hexenol cis 3 (CAS 928-96-1), terpineol (CAS 8000-41-7), linalool (CAS 78-70-6), tetrahydrolinalool (CAS 78-69-3), triethyl citrate (CAS 77-93-0), 2-isobutyl-4-hydroxy-4-methyltetrahydropyran (CAS 63500-71-0), hexyl salicylate (CAS 6259-76-3), phenylethyl alcohol (CAS 60-12-8), 3 Methyl 5-phenyl-1-pentanol (CAS 55066-48-3), 2,6-dimethyl-7-octen-2-ol (CAS 18479-58-8), benzyl salicylate (CAS 1 18-58- 1), geraniol (CAS 106-24-1), citronellol (CAS 106-22-9) and ethyllinalool (CAS 10339-55-6);
  • Group B alcohols and diols and
  • Group C Substances with at least three hydroxyl groups.
  • Particularly advantageous stabilizers from group A are: linalool (CAS 78-70-6), benzyl salicylate (CAS 1 18-58-1), geraniol (CAS 106-24-1) and citronellol (CAS 106-22-9 ).
  • Particularly advantageous group B stabilizers are: ethanol, 2-propanol, PEG 8, triethylene glycol, methylphenylbutanol, decanediol, polyglyceryl-2-caprate, oxalic acid.
  • Particularly advantageous stabilizers from group C are: sucrose (mannose, mannitol), glycerol, pentaerythritol, threitol, erythritol, hyaluronic acid.
  • compositions of first and second part preparation containing stabilizers selected from the group A, B and / or C allows the reduction or prevention of stress sweating.
  • the partial preparations of the process according to the invention or of the process-converting products comprise no further antiperspirant active substances or preparations, in particular no aluminum salts, in particular no ACH and / or AACH (activated aluminum chlorohydrate).
  • no further antiperspirant active substances or preparations in particular no aluminum salts, in particular no ACH and / or AACH (activated aluminum chlorohydrate).
  • Process-converting products are products when used
  • inventive method is performed.
  • the part preparations are preferably produced and used in an optically appealing transparent manner.
  • the first part preparation is advantageously characterized in that it is in the form of an aqueous or aqueous-alcoholic solution, or an anhydrous preparation.
  • deodorants can also be added to the first and / or the second part preparation.
  • the usual cosmetic deodorants are based on different active principles.
  • antimicrobial substances as cosmetic deodorants, the bacterial flora on the skin can be reduced.
  • only the odor causing microorganisms should be effectively reduced.
  • the sweat flow itself is not influenced by this, in the ideal case only the microbial decomposition of the sweat is temporarily stopped.
  • the combination of astringents with antimicrobial substances in one and the same composition is also common.
  • odor maskers such as the customary perfume ingredients
  • odor absorbers for example the phyllosilicates described in DE 40 09 347, of these
  • Germ-inhibiting agents are also suitable for incorporation into the preparations according to the invention.
  • Advantageous substances are, for example, 2,4,4'-trichloro-2'-hydroxydiphenyl ether (Irgasan), 1,6-di- (4-chlorophenylbiguanido) hexane (chlorhexidine), 3,4,4'-trichlorocarbanilide, quaternary ammonium compounds, clove oil, mint oil, thyme oil, triethyl citrate, farnesol (3,7,1-trimethyl-2,6,10-dodecatrien-1-ol), ethylhexylglycerol, phenoxyethynol, piroctone olamine,
  • an antimicrobial silver citrate complex as described in DE 202008014407, preferably be used as a deodorizing ingredient.
  • the first and / or the second part of the preparation also contain polymers.
  • the polymers are preferably from the range of celluloses, such as hydroxyethyl or hydroxypropylcellulose, the acrylic acid-containing polymers, such as carbomers, and / or
  • Polyvinylpyrrolidones are advantageously hydrophobic or hydrophilic modified. They serve the viscosity adjustment of the phases and facilitate the pumpability and miscibility, as well as the drainage or distribution behavior on the skin.
  • ethanol and isopropanol, glycerol and propylene glycol, skin-care fat or fat-like substances and oils such as oleic acid decyl ester, cetyl alcohol, cetylstearyl alcohol and 2-octyldodecanol, which are customary for such preparations, can be used as conventional cosmetic ingredients of the second part preparation of the product according to the invention
  • the second part preparation can advantageously one or more nonionic compounds
  • Emulsifiers these are advantageously selected from the group consisting of polyoxyethylene (20) sorbitan monolaurate, polyoxyethylene (20) sorbitan monopalmitate, polyoxyethylene (20) sorbitan monostearate, polyoxyethylene (20) sorbitan monooleate, sorbitan trioleate, polyglyceryl-10 Stearates, Polyglyceryl-4 Caprate, Lauryl Glucoside, Polyglyceryl-2 Dipolyhydroxyl Stearate, Polyglyceryl-10 Laurate, Polyglyceryl-4 Laurate, Decyl Glucoside, Propylene Glycol
  • Glyceryl isostearates glyceryl stearates, steareth-2, ceteareth-20, steareth-21, PEG-40 hydrogenated castor oil, PG-10 stearates, isoceteth-20, isosteareth-20 and / or ceteareth-12 are preferably used as nonionic emulsifiers ,
  • the second part preparation is a solution or emulsion or dispersion, it is possible to use as solvent, bodying agent and / or main active ingredients:
  • Oils such as triglycerides of capric or caprylic acid and alkyl benzoate,
  • esters of fatty acids with low C-number alcohols eg with isopropanol, propylene glycol or glycerol, or esters of fatty alcohols with lower C-number alkanoic acids or with fatty acids
  • Vegetable oils such as avocado oil, meadowfoam seed oil, Olive oil, sunflower oil, rapeseed oil, almond oil, evening primrose oil, coconut oil. Palm oil, linseed oil, shea butter.
  • Alcohols, diols or polyols of low C number, and their ethers in particular propylene glycol, glycerol, ethylene glycol, ethylene glycol monoethyl or monobutyl ether, propylene glycol monomethyl, monoethyl or monobutyl ether, diethylene glycol monomethyl or monoethyl ether and analogous products.
  • Skin care substances such as Panthenol, allantoin, urea
  • mixtures of the aforementioned ingredients are used.
  • water can be another ingredient.
  • the process-converting cosmetic products have at least two separate chambers.
  • Examples are in particular bicameral aerosol containers
  • a double pump device wherein one chamber contains the first part preparation and the second chamber contains the second part preparation.
  • a good method is also the spreading or rubbing by means of flat applicators, which are fed by a two-chamber container, in particular applicators with flocked and / or textile surface, since they have a low tendency to clog.
  • Pump sprays like the aerosol sprays, provide a non-contact application to the skin.
  • pressure-resistant containers can be dispensed with.
  • Two-chamber pump sprays can be made metal-free, in particular aluminum-free.
  • Advantageous containers are made of PE, PP or PET, which are closed with one or two metal-free spray pump (s), where metal-free means that the pumped preparation does not come into contact with metallic components.
  • metal-free spray pump s
  • the supply takes place via one or two risers and the mixture of the first and second part preparation before or after the pump (s).
  • Suitable propellants for preparations which can be sprayed from aerosol containers in the sense of the present invention are the customary known highly volatile, liquefied propellants, for example hydrocarbons (propane, butane, isobutane), which can be used alone or mixed with one another. Dimethyl ether, nitrous oxide, carbon dioxide, nitrogen and compressed air are also advantageous to use.
  • Partial preparation according to the invention further cosmetic adjuvants, such as are commonly used in cosmetic preparations, e.g. Preservatives, preservatives, bactericides, perfumes, UV filters, antioxidants, water-soluble vitamins, minerals, suspended solid particles, foaming inhibitors, colorants, pigments having a coloring effect, thickeners, moisturizing and / or moisturizing substances or others usual ingredients of a cosmetic or dermatological formulation such as electrolytes, organic
  • Solvents Solvents, alcohols, polyols, emulsifiers, polymers, foam stabilizers or Sili konderivate.
  • Example 1 For a comparative study, the partial preparations listed in Table 1 were prepared. In each case, a mixture of the 1st and 2nd part of Example 1 of the invention Example 1 malonic acid and the 1st and 2nd part of the preparation of the non-inventive Example Com. 1 containing lactic acid produced and examined in a study with regard to their sweat-reducing effect. The concentrations of malonic acid and lactic acid were adjusted so that when mixing the
  • Part preparations for Ex1 and Com.1 are each 6% by weight.
  • the total amount of S1O2 in the total mixture is 3% by weight, based on the total weight of the mixture.
  • preparation Bsp.1 showed a significant mean reduction in sweat of 39% in the participants. On the other hand, the showed

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Cosmetics (AREA)

Abstract

L'objet de l'invention est une trousse comprenant au moins deux préparations cosmétiques partielles, une première préparation partielle comprenant au moins un silicate de métal alcalin et une deuxième préparation partielle comprenant au moins de l'acide malonique.
EP19719179.4A 2018-05-17 2019-04-10 Procédé de réduction de sueur à l'acide malonique Withdrawn EP3793509A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102018207702.9A DE102018207702A1 (de) 2018-05-17 2018-05-17 Verfahren zur Schweißreduktion mit Malonsäure
PCT/EP2019/059039 WO2019219300A1 (fr) 2018-05-17 2019-04-10 Procédé de réduction de sueur à l'acide malonique

Publications (1)

Publication Number Publication Date
EP3793509A1 true EP3793509A1 (fr) 2021-03-24

Family

ID=66251731

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19719179.4A Withdrawn EP3793509A1 (fr) 2018-05-17 2019-04-10 Procédé de réduction de sueur à l'acide malonique

Country Status (3)

Country Link
EP (1) EP3793509A1 (fr)
DE (1) DE102018207702A1 (fr)
WO (1) WO2019219300A1 (fr)

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2962420A (en) * 1957-07-16 1960-11-29 Univ Illinois Method of inhibiting perspiration and compositions therefor
CA1085299A (fr) * 1976-03-05 1980-09-09 Joseph D. Mandell Compose a base d'acide lactique et mode d'emploi
DE3740186A1 (de) 1987-06-24 1989-01-05 Beiersdorf Ag Desodorierende und antimikrobielle zusammensetzung zur verwendung in kosmetischen oder topischen zubereitungen
DE3938140A1 (de) 1989-11-16 1991-08-08 Beiersdorf Ag Desodorierende kosmetische mittel
DE4009347A1 (de) 1990-03-23 1991-09-26 Beiersdorf Ag Desodorierende kosmetische mittel
DE4204321A1 (de) 1992-02-13 1993-08-19 Beiersdorf Ag Verfahren zur isolierung und reinigung von fettsaeuren und hydroxyfettsaeuren und verwendungen von hydroxyfettsaeuren sowie zubereitungen, die sie enthalten
DE4229737C2 (de) 1992-09-05 1996-04-25 Beiersdorf Ag Desodorierende kosmetische Mittel mit einem Gehalt an Fettsäuren
DE4229707A1 (de) 1992-09-05 1994-03-10 Beiersdorf Ag Germicide Wirkstoffkombinationen
DE4237081C2 (de) 1992-11-03 1996-05-09 Beiersdorf Ag Verwendung von Di- oder Triglycerinestern als Deowirkstoffe
DE4309372C2 (de) 1993-03-23 1997-08-21 Beiersdorf Ag Kosmetische Desodorantien, enthaltend Gemische aus Wollwachssäuren oder Wollwachssäurekomponenten und Fettsäurepartialglyceriden unverzweigter Fettsäuren
DE4324219C2 (de) * 1993-07-20 1995-08-10 Beiersdorf Ag Desodorierende Wirkstoffkombinationen auf der Basis von alpha, omega-Alkandicarbonsäuren und Wollwachssäuren
DE4423410C2 (de) * 1994-07-04 1996-07-18 Beiersdorf Ag Desodorierende Wirkstoffkombinationen auf der Basis von alpha, omega-Alkandicarbonsäuren und Monocarbonsäureestern von Oligoglyceriden
FR2789371B1 (fr) * 1999-02-05 2001-04-27 Sofab Distributeur de produits chimiquement instables
DE10103692A1 (de) * 2001-01-26 2002-08-01 Margarete Bialowitz-Sagala Antiperspirant-und Desodorant-Wirkstoffe
DE102008031927B4 (de) 2008-07-08 2017-09-14 Beiersdorf Ag Kosmetische Zubereitungen mit passiviertem Silber
FR2977151B1 (fr) 2011-06-28 2013-09-27 Oreal Utilisation cosmetique comme actif anti-transpirant d'un silicate alcalin
GB201402669D0 (en) * 2014-02-14 2014-04-02 Medical Res Council Stabilised silicate compositions and their uses
DE102015226630A1 (de) * 2015-12-23 2017-06-29 Beiersdorf Ag Verfahren zur Schweißreduktion

Also Published As

Publication number Publication date
DE102018207702A1 (de) 2019-11-21
WO2019219300A1 (fr) 2019-11-21

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