WO2019206466A1 - Préparation à action anti-transpirante comprenant des sels de métal alcalino-terreux et des acides carboxyliques - Google Patents

Préparation à action anti-transpirante comprenant des sels de métal alcalino-terreux et des acides carboxyliques Download PDF

Info

Publication number
WO2019206466A1
WO2019206466A1 PCT/EP2019/051050 EP2019051050W WO2019206466A1 WO 2019206466 A1 WO2019206466 A1 WO 2019206466A1 EP 2019051050 W EP2019051050 W EP 2019051050W WO 2019206466 A1 WO2019206466 A1 WO 2019206466A1
Authority
WO
WIPO (PCT)
Prior art keywords
acid
preparation
alkaline earth
earth metal
metal salts
Prior art date
Application number
PCT/EP2019/051050
Other languages
German (de)
English (en)
Inventor
Dorothea Schweiger
Annika Patricia RING
Clare VICKERS
Lätitia Neumann
Robert Klauck
Frank Lehmbeck
Elke Grotheer
Original Assignee
Beiersdorf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beiersdorf Ag filed Critical Beiersdorf Ag
Priority to EP19700920.2A priority Critical patent/EP3784203A1/fr
Priority to BR112020018031-9A priority patent/BR112020018031A2/pt
Priority to AU2019259299A priority patent/AU2019259299A1/en
Publication of WO2019206466A1 publication Critical patent/WO2019206466A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00—Anti-perspirants or body deodorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A61K8/068—Microemulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20—Halogens; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/342—Alcohols having more than seven atoms in an unbroken chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/88—Two- or multipart kits
    • A61K2800/884—Sequential application

Definitions

  • Antiperspirant active preparation comprising alkaline earth metal salts and carboxylic acids
  • the invention is a combination of one or more alkaline earth metal salts and one or more carboxylic acids in cosmetic or dermatological formulations having a pH of less than 5.
  • Also according to the invention is a combination of at least two preparations, one preparation comprising the carboxylic acid and the other preparation comprising the soluble alkaline earth metal salts.
  • secreted aqueous secretion There are three types of sweat glands in the skin, namely, apocrine, eccrine, and apoekrine sweat glands (Int J Cosmet Sei. 2007 Jun;
  • the eccrine sweat glands in humans are distributed practically throughout the body and can produce significant amounts of a clear, odorless secretion that is over 99% water.
  • the apocrine sweat glands occur only in the hairy body areas of the armpit and genital region and on the nipples. They produce small amounts of a milky secretion that contains proteins and lipids and is chemically neutral.
  • Sweating also known as transpiration, is an effective mechanism to release excess heat and thereby regulate body temperature.
  • the volume-rich aqueous secretion of the eccrine glands which can produce up to 2-4 liters per hour or 10-14 liters a day in adults, is used for this purpose.
  • the sweat - especially the secretion of apocrine sweat glands - is also signaled by the sense of smell. In humans, the apocrine sweat plays in particular in connection with the emotional or stress related
  • Cosmetic antiperspirants or deodorants / deodorants are used to eliminate body odor or to reduce their formation.
  • Body odor arises when the per se odorless fresh sweat by microorganisms such. Staphylococci and
  • Corynebacteria is decomposed.
  • the usual cosmetic deodorants are based on different active principles.
  • deodorant and "antiperspirant”. Rather, especially for German-speaking countries, products for use in the armpit area are referred to as deodorants or "deodorants”. This is irrelevant to the question of whether an antiperspirant effect is present.
  • Antiperspirants are antiperspirants which, in contrast to the deodorants which generally prevent microbial decomposition of already formed perspiration, are said to prevent the secretion of sweat at all.
  • AT preparations may additionally contain substances which inhibit the microbial degradation of the perspiration, such as, for example, Triclosan.
  • Triclosan has an effect against gram-positive and gram-negative bacteria as well as against fungi and yeasts, which results in a deodorizing, but no antiperspirant effect, as no influence on the sweat secretion can be deduced from the influence on the bacterial skin flora.
  • Odor neutralization (masking), influencing of bacterial metabolisms, the pure perfuming as well as the use of precursors of certain perfume components, which are converted by enzymatic reactions to fragrant substances.
  • Antiperspirant active agents, etc. achieved by a "blockage of the sweat gland". They work by blocking sweat gland excretions by precipitating them together with the skin's own proteins, leading to so-called plugs.
  • Corneocytes in the sweat duct (Shelley WB and Hurley HJ, Acta, Derm. Venereol. (1975) 55: 241-60), or by the formation of an ACH / AZG gel (Reller HH and Luedders WL, in: Advances in Modern Hemisphere Publishing Company, Washington and London (1977) Vol. 4: 1-5), which is formed by neutralization in the sweat gland duct, remains open. The thus obtained and known constipation is effective only in the short term. strong
  • Antiperspirant drugs are (Reller, Lüdders, Pharmacologic and Toxicological Effects of Topically Applied Agents on the eccrine sweat glands, Vol 4, p 18, 1975).
  • WO 2013013999 A2 describes the antiperspirant activity (sweat reduction) of alkaline earth metal salts.
  • Compounds of polyvalent cations such as beryllium, magnesium, calcium, strontium, barium, titanium, manganese, zinc, hafnium and aluminum, with anions from the group of the halides and carboxylic acids are listed as being AT-active and only the salts acetate, propionate , Pyrrolidonecarboxylate,
  • DE 102015226630 A1 discloses silica in a 2-chamber packing agent for
  • the pH of the silica-containing preparations is preferably from 5.1 to 6.9.
  • the consumer expects a sweat inhibition that lasts at least one working day.
  • the invention is a cosmetic or dermatological hydrous and / or alcoholic preparation comprising one or more alkaline earth metal salts and one or more
  • the alkaline earth metal salts added to the preparation are water-soluble.
  • the pH of the preparation is adjusted to a value of less than 5, in particular in the range of 4.5 and smaller.
  • the preparation of the invention is antiperspirant active without further processing
  • antiperspirant substances in particular aluminum salts, are present.
  • antiperspirant preparations according to the invention and as antiperspirants is also part of the present invention.
  • the preparations according to the invention are used for reducing sweat primarily in the armpit.
  • the formulations can also be used to reduce the sweat flow on other body areas where consumers sweat undesirable. This may be, but is not limited to, the feet, the forehead, the palms or the back. Due to the advantageous freedom of aluminum, the
  • the formulations are applied in a form that is acceptable to the consumer, which can be advantageous, for example, pump sprays, sprays with aerosols, ball applicators, pens, tubes, soft-touch applicators, capsules.
  • Be precipitated such as alkaline earth metal soaps of fatty acids
  • a common preparation of cosmetic preparations are emulsions.
  • Alkaline earth metal salts such as magnesium stearate are known in cosmetic preparations.
  • magnesium stearate can be used to increase the consistency in oil phases of
  • Emulsions are used.
  • a typical example is the well-known Nivea cream.
  • alkaline earth metal salts such as the chlorides
  • anion of the fatty acid form the alkaline earth metal salt of the fatty acid, which is only soluble in the oil phase, and which then greatly increases the viscosity.
  • the sparingly soluble alkaline earth metal salts of carboxylic acids are not added directly to the difference in the prior art, but soluble
  • Alkaline earth metal salts such as magnesium chloride
  • the carboxylic acids in the oil phase and the pH is adjusted below 5.
  • the water-soluble alkaline earth salts such as magnesium chloride
  • the carboxylic acid such as, for example, stearic acid
  • the salt of the fatty acid is already formed in the preparation, and so does the Viscosity strong, which in turn is known as a strong thickener for oil phases, which should be avoided.
  • the pH of the preparation is set in the range of less than 5, especially less than 4.5, and surprisingly no precipitation of the poorly soluble magnesium fatty acid salt is observed.
  • an emulsion are the two
  • the pH of the preparation applied to the skin is in the range of greater than 4 or greater a precipitate of the sparingly soluble alkaline earth metal fatty acid salts, such as Magnesium stearate, observed.
  • Alkaline earth precipitates, which precipitate in sweat gland ducts, causing constriction or blockage, thereby inhibiting perspiration.
  • the formulation contains stearic acid, which, as soon as the product is applied to the skin, dissociates and together with the magnesium chloride forms the insoluble magnesium stearate, which is ultimately responsible for the sweat reduction.
  • the preparation of the invention has a pH of less than 5, preferably between 3.5 and 4.5, in particular in the range of 3.8 to 4.2, so that the preparation stored without precipitation and ready for application Available.
  • the low pH value according to the invention was surprisingly also advantageous with respect to the consistency of the preparation.
  • the invention is also a combination of at least cosmetic or dermatological preparations to provide, wherein in one preparation, the carboxylic acids and in another preparation, the alkaline earth metal salts are included.
  • the application and use of these preparations is then advantageously in a 2-step application or from a 2-chamber packaging.
  • a preparation may be applied to the skin comprising the carboxylic acid, such as stearic acid.
  • step 2 a preparation comprising the alkaline earth metal salt such as MgC is applied.
  • Magnesium stearate leads to the described sweat reduction due to the pore narrowing by the forming precipitates.
  • alkaline earth metal salts such as the preferred magnesium, calcium and strontium halides, are added to the formulation.
  • sparingly soluble alkaline earth metal salts of the fatty acids such as, for example, magnesium, calcium or strontium stearate, palmitate, myristate, or oleate.
  • the salts referred to as sparingly soluble alkaline earth metal salts are not to be understood as those salts which are known as soluble alkaline earth metal salts of the
  • Alkaline earth metal precipitates on the skin leading to blockage or narrowing of
  • a preparation according to the invention to the skin and an thereby occurring pH value of the preparation on the skin, which leads to the formation of the alkaline earth metal precipitates.
  • a method according to the invention also comprises the sequence of
  • Alkaline earth metal salts and then or at the same time the application of a second preparation to the same site of the skin then comprising each of the previous preparation not present carboxylic acid or soluble alkaline earth metal salts.
  • a preferably non-therapeutic antiperspirant process which is characterized by the application of a preparation to the skin, if the preparation comprises at least water, or alcohol, a carboxylic acid and a water-soluble alkaline earth metal salt and the preparation thereby has a pH of less than 5 having.
  • Preferred methods are non-therapeutic methods, cosmetic methods that lead to cosmetic sweat reduction or inhibition.
  • the processes are preferred in which, as alkaline earth metal salts, magnesium or calcium chlorides and as carboxylic acids one or more acids selected from adipic acid, arachidic acid, lauric acid, myristic acid, caprylic acid, capric acid, oleic acid, plamitic acid, behenic acid, linolenic acid, stearic acid and / or tartaric acid , in particular stearic acid and palmitic acid.
  • carboxylic acids one or more acids selected from adipic acid, arachidic acid, lauric acid, myristic acid, caprylic acid, capric acid, oleic acid, plamitic acid, behenic acid, linolenic acid, stearic acid and / or tartaric acid , in particular stearic acid and palmitic acid.
  • the preparations according to the invention can be prepared, for example, as follows.
  • the water phase and fat phase are heated and combined with stirring. Subsequently, the emulsion is cooled down with stirring and the active substance phase, the soluble
  • Alkaline earth metal salts such as magnesium chloride
  • Preferred carboxylic acids according to the invention are one or more acids selected from the group consisting of adipic acid, arachidic acid, succinic acid, lauric acid, maleic acid, malonic acid, myristic acid, oleic acid, palmitic acid, stearic acid and / or tartaric acid.
  • a mixture of several of these acids is to be selected, in particular a mixture comprising palmitic acid, stearic acid, myristic acid, oleic acid and arachidic acid.
  • alkaline earth salts are preferably used magnesium, calcium and
  • Strontium halides in particular magnesium chloride and its hydrates, in particular hydrates to MgCl 2 * 6H 2 ⁇ , in particular MgCl 2 * 6H 2 ⁇ , and / or calcium chloride, and
  • the preparations according to the invention differ from prior art formulations comprising alkaline earth metal salts of the cited carboxylic acids, such as magnesium stearate, solely in that the two substances essential to the invention, water-soluble alkaline earth metal salt and carboxylic acid are present separately from one another.
  • Preparations comprising alkaline earth salts of the acids adipic acid, arachidic acid, succinic acid, lauric acid, maleic acid, malonic acid, myristic acid, oleic acid, palmitic acid, stearic acid and / or tartaric acid are therefore not according to the invention.
  • the preparations according to the invention are antiperspirant active, antiperspirant preparations solely from the inventive combination of water-soluble alkaline earth metal salt, carboxylic acid and pH below 5. Also herein
  • the preparations according to the invention differ from prior art preparations containing another AT active ingredient.
  • Antiperspirant active cosmetic or dermatological preparations are preferred according to the invention.
  • carboxylic acids selected from adipic acid, arachidic acid, lauric acid, myristic acid, caprylic acid, capric acid, oleic acid, plamitic acid,
  • Behenic acid, linolenic acid, stearic acid and / or tartaric acid in particular
  • the proportion of one or more alkaline earth salts is preferably selected in the range from 5 to 20% by weight, in particular in the range from 7 to 10% by weight, based on the total mass of the preparation.
  • the proportion of one or more carboxylic acids is advantageously selected in the range from 1 to 5% by weight, in particular in the range from 2 to 4, based on the total mass of the preparation.
  • antiperspirant active substances in particular no aluminum salts such as
  • Aluminiumchlorohydrate added to the preparations of the invention.
  • antiperspirant antiperspirant substances
  • 0.1 wt.% In particular at 0 wt.%, Based on the total mass of the preparation to refer by introduction or impurities and these as free of additional AT-active ingredients ,
  • Preparations according to the invention are preferably O / W emulsions, W / O emulsions, aqueous-alcoholic preparations, alcoholic (ethanolic) solutions, PIT emulsions or hydrodispersions.
  • the preparations according to the invention comprise one or more lipids.
  • Preferably used lipids are selected from the group of Capric / Caprylic
  • Octyldodecanol Paraffinum Liquidum, Isododecane, Isopropyl Palmitate, Persea Gratissima, Caprylyl Carbonate, Helianthus Annuus, Ethylhexyl Cocoate, C12-15 Alkyl Benzoate,
  • Cyclomethicones and / or dimethicones phenyltrimethicone, sunflower oil, rapeseed oil,
  • Capric / Caprylic Triglyceride Isopropyl Myristate, Isopropyl Palmitate, Isopropyl Stearate, Cetearyl Ethylhexanoate, Hydrogenated Polydecene, Glycine Soybean Oil, Olive Oil, Guerbet Alcohols such as hexyldecanol, octyldodecanol and 2-ethylhexylalcohol. also Guerbet alcohol esters, and mixtures of Guerbet alcohols and Guerbetalkoholestem, such as hexyldecanol and hexyldecyl laurate.
  • the preparations according to the invention are advantageously one or more
  • Emulsifiers from the group of nonionic emulsifiers such as, for example, propylene glycol isostearate (HLB 2.5), glycol stearate (HLB 2.9), glyceryl isostearate (HLB 3.5),
  • Sorbitan sesquioleate (HLB 3.7), glyceryl stearate (HLB 3.8), lecithin (HLB 4), sorbitan oleate (HLB 4.3), sorbitan monostearate NF (HLB 4.7), sorbitan stearate (HLB 4.7), sorbitan
  • Hydrogenated Castor Oil (HLB 10.8), Stearamide MEA (HLB 11), Glyceryl Stearate (and) PEG-100 Stearate (HLB 11), Polysorbate 85 (HLB 11), PEG-7 Olivate (HLB 11), Cetearyl Glucoside (HLB 11 ), PEG-8 oleate (HLB 11.6), polyglyceryl-3-methylglucose distearate (HLB 12), PG-10 stearate (HLB 12), oleth-10 (HLB 12.4), oleth-10 / polyoxyl 10 oleyl ether NF (HLB 12.4 ), Ceteth-10 (HLB 12.9), PEG-8 Laurate (HLB 13), Ceteareth-12 (HLB 13.5), Cocamide MEA (HLB 13.5), Polysorbate 60 NF (HLB 14.9), Polysorbate 60 (HLB 14.9) , PEG-40 Hydrogenated Castor Oil (HLB 15), Polysorbate 80 (HLB 15), isosteare
  • the emulsions of the invention may also contain anionic or cationic emulsifiers.
  • Preferred suitable cationic emulsifiers are selected from the group Cetrimonium Chloride, Palmitamidopropyltrimonium Chloride, Quaternium-87, Behentrimonium Chloride, Distearoylethyl Dimonium Chloride, Distearyldimonium Chloride, Stearamidopropyl Dimethylamine and / or Behentrimonium Methosulfate.
  • rheology modifiers are natural organic polymers and their derivatives, gum arabic, karaya, tragacanth, locust bean gum, guar, pectin, agar, carrageenan, alginates, xanthan, starch and starch derivatives, cellulose and cellulose derivatives such as microcrystalline cellulose, methylcellulose, cellulose gum, hydroxyethyl cellulose, Hydroxylpropylcellulose, methylhydroxypropylcellulose, further inorganic gelling agents, such as silicates, eg bentonites, hectorites, colloidal silicic acid; in addition, synthetic thickeners such as polyvinyl alcohol and also ethoxylated compounds such as poloxamer, PEG-150 distearate, PEG-120 methyl glucose dioleate, PEG-9 dilaurates and fatty alcohols such as stearyl alcohol, cetyl alcohol and cetearyl alcohol.
  • aqueous phase of the preparations according to the invention may advantageously contain customary cosmetic auxiliaries, for example alcohols, in particular those of low C number, such as isopropanol, diols or polyols of low C number and also their ethers, preferably
  • Propylene glycol 2-methylpropane-1,3-diol, pentane-1,2-diol, hexane-1,2-diol, octane-1,2-diol, decane-1,2-diol, glycerol, ethylene glycol, ethylene glycol monoethyl or monobutyl ether, propylene glycol monomethyl, monoethyl or monobutyl ether, diethylene glycol monomethyl or monoethyl ether and analogous products, foam stabilizers, electrolytes, etc.
  • the preparation according to the invention is characterized in that the preparation is propylene glycol, butylene glycol, 2-methylpropane-1, 3-diol, 1, 2-pentanediol, 1, 2-hexanediol, 1, 2-octanediol and / or 1, 2-decanediol contains.
  • Suitable acids may include citric acid, lactic acid, maleic acid, malonic acid, succinic acid,
  • Hydroxysuccinic acid (malic acid), fumaric acid, salicylic acid, etidronic acid, phosphoric acid, hydrochloric acid and sulfuric acid.
  • Suitable alkalizing agents for creating a buffer system for example, sodium hydroxide, potassium hydroxide, ammonia, mono-, di- and trialkylamines and the
  • Hydroxyalkylamines aminomethyl propanol (2-amino-2-methylpropan-1-ol), ethanolamine (2-aminoethanol), triethanolamine (2,2 ', 2 "-nitrilotriethanol) and tetrahydroxypropyl ethylenediamine (1,1', 1", 1 '"-Ethylendinitrilotetrapropan-2-ol).
  • the armpits were washed with perfume-free soap (Baktolin pH 5.5) for approx. 30 seconds per armpit before the 2nd, 3rd and 4th application. After the tO measurement, the subjects were allowed
  • test samples were allied and randomized in a defined amount applied on one side. After each application followed by a 30-minute
  • the measurements related to the left and right axilla of a subject The 40-minute period of sweating became unbalanced, and the 2-minute 20-minute periods were followed by well-balanced pads that absorbed sweat during the period. The pads of the sweat phase were discarded. After the
  • Measuring phases took place the delivery of the pads in the appropriate plastic containers. By a gravimetric determination the sweat quantities of the measuring phases 1 and 2 for the left and right armpit were determined. The measurements in the hotroom took place under the climatic conditions
  • Sweat reduction of 13.5% corresponds. This shit reduction is also significant.
  • the preparation comprises water and / or alcohol and has a pH of less than 5.
  • one or more deodorizing agents are advantageously added to the preparations according to the invention.
  • deodorizing agents may preferably be selected from cationic polymers, in particular Polyquaternium-16, Polyquaternium-7, Polyquaternium-6, Polyquaternium-11 and Polyquaternium 37, polyaminopropyl biguanide and epsilon-polylysine.
  • deodorizing agents may also be advantageous octenidine hydrochloride
  • Alexidine dihydrochloride benzyl alcohol, benzalkonium chloride, cetyltrimethylammonium chloride, silver citrate, triclosan, ethylhexylglycerol, triethyl citrate, 2-butyloctanoic acid, methylphenylbutanol, phenoxyethanol, zinc ricinoleate, and other drugs that reduce the number of bacteria on the skin.
  • the preparations according to the invention therefore preferably also comprise one or more polyquaternium polymers.
  • polyquaternium polymers are selected from the group of polyquaternium-16 polymers and polyquaternium-6 polymers. These are in accordance with the invention Preparations in a proportion of 0, 1 to 10 wt.%, In particular in a proportion of 0, 15 to 5 wt.%, Based on the total mass of the preparation containing.
  • polyquaternium-16 polymers (3-methyl-1-vinylimidazolium chloride-1-vinyl-2-pyrrolidinone chlorides) are selected. According to the invention, the polyquaternium polymers used, and in particular PQ-16 polymers, have an additional antimicrobial activity.
  • Polyquaternium polymers containing one or more other deodorant substances are used.
  • the cosmetic or dermatological preparations according to the invention may further contain cosmetic adjuvants and active ingredients, such as are usually present in such
  • Preparations are used, for. As agents, preservatives, preservatives, bactericides, lipids, substances for preventing foaming, dyes and
  • Color pigments, thickeners, moisturizing and / or moisturizing substances or other customary constituents of a cosmetic or dermatological formulation such as polyols, polymers, foam stabilizers, organic solvents or silicone derivatives, if the additive has the required properties with respect to stability, pH values and AT effect not impaired or excluded.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Cosmetics (AREA)

Abstract

Une association d'un ou de plusieurs sels de métal alcalino-terreux et d'un ou de plusieurs acides carboxyliques dans des préparations cosmétiques ou dermatologiques ayant un pH inférieur à 5 produit un effet anti-transpirant synergique. Cette association peut être composée d'au moins deux préparations, une préparation renfermant l'acide carboxylique et l'autre préparation renfermant les sels de métal alcalino-terreux solubles.
PCT/EP2019/051050 2018-04-27 2019-01-16 Préparation à action anti-transpirante comprenant des sels de métal alcalino-terreux et des acides carboxyliques WO2019206466A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP19700920.2A EP3784203A1 (fr) 2018-04-27 2019-01-16 Préparation à action anti-transpirante comprenant des sels de métal alcalino-terreux et des acides carboxyliques
BR112020018031-9A BR112020018031A2 (pt) 2018-04-27 2019-01-16 Preparação com eficácia antitranspirante compreendendo sais de metais alcalino-terrosos e ácidos carboxílicos
AU2019259299A AU2019259299A1 (en) 2018-04-27 2019-01-16 Antiperspirant preparation comprising alkaline earth metal salts and carboxylic acids

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102018206624.8A DE102018206624A1 (de) 2018-04-27 2018-04-27 Antitranspirantwirksame Zubereitung umfassend Erdalkalimetallsalze und Carbonsäuren
DE102018206624.8 2018-04-27

Publications (1)

Publication Number Publication Date
WO2019206466A1 true WO2019206466A1 (fr) 2019-10-31

Family

ID=65036806

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2019/051050 WO2019206466A1 (fr) 2018-04-27 2019-01-16 Préparation à action anti-transpirante comprenant des sels de métal alcalino-terreux et des acides carboxyliques

Country Status (5)

Country Link
EP (1) EP3784203A1 (fr)
AU (1) AU2019259299A1 (fr)
BR (1) BR112020018031A2 (fr)
DE (1) DE102018206624A1 (fr)
WO (1) WO2019206466A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102020207685A1 (de) 2020-06-22 2021-12-23 Beiersdorf Aktiengesellschaft Kosmetische Zubereitung umfassend schweißhemmende anorganische Salze, Carbonsäuren und 1,3-Propandiol
WO2022122598A1 (fr) 2020-12-07 2022-06-16 Unilever Ip Holdings B.V. Compositions antitranspirantes
EP3866935B1 (fr) 2018-10-18 2022-08-10 Unilever Global Ip Limited Procédé de réduction de la transpiration
AU2019376458B2 (en) * 2018-11-06 2023-05-04 Unilever Global Ip Limited Antiperspirant compositions

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102019216547A1 (de) * 2019-10-28 2021-04-29 Beiersdorf Ag Kosmetische Zubereitung umfassend Erdalkalimetallsalze, Carbonsäuren und Emulgatoren mit verzweigter hydrophober Kette
WO2024033154A1 (fr) * 2022-08-11 2024-02-15 Unilever Ip Holdings B.V. Compositions déodorantes d'émulsion

Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1070500A1 (fr) * 1998-12-18 2001-01-24 Kao Corporation Composition desodorisante
US20050036968A1 (en) * 2003-08-14 2005-02-17 The Gillette Company Enhanced efficacy antiperspirant compositions containing strontium
DE102005012476A1 (de) 2005-03-16 2006-09-21 Henkel Kgaa Inhibitoren von Staphylococcus hominis in Deodorantien und Antitranspirantien
WO2007071474A1 (fr) 2005-12-16 2007-06-28 Beiersdorf Ag Action longue duree amelioree d'antitranspirants
WO2009012925A2 (fr) * 2007-07-24 2009-01-29 Beiersdorf Ag Formulation cosmétique ou dermatologique contenant de l'acide mandélique d ou l
FR2940062A1 (fr) * 2008-12-19 2010-06-25 Oreal Agent multi composants anti-transpirant comprenant deux composes capables de reagir par interaction physique et procede de traitement de la transpiration humaine en deux etapes
WO2013013999A2 (fr) 2011-07-22 2013-01-31 L'oreal Utilisation, comme anti-transpirant, d'un sel de cation multivalent sans anti-transpirant de type halogénure d'aluminium ou composé apte à réagir avec ledit sel afin de produire un effet anti-transpirant
EP2857482A1 (fr) * 2012-06-01 2015-04-08 Kao Corporation Composition de parfum
WO2015051805A1 (fr) * 2013-10-09 2015-04-16 Riemann Trading Aps Composition antiperspirante améliorée
EP3000459A1 (fr) * 2014-09-29 2016-03-30 Johnson & Johnson Consumer Inc. Compositions anti-transpirantes
DE102014222270A1 (de) 2014-10-31 2016-05-04 Thomas Brunner Hygiene GmbH Kosmetische Antitranspirant-Zusammensetzung
DE102015214143A1 (de) * 2015-07-27 2017-02-02 Beiersdorf Ag Schweiß verringernde kosmetische Zubereitung
DE102015011694A1 (de) * 2015-09-14 2017-03-16 Forschungszentrum Jülich GmbH Reinigungsmittel auf Mikroemulsionsbasis
DE102015226630A1 (de) 2015-12-23 2017-06-29 Beiersdorf Ag Verfahren zur Schweißreduktion

Patent Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1070500A1 (fr) * 1998-12-18 2001-01-24 Kao Corporation Composition desodorisante
US20050036968A1 (en) * 2003-08-14 2005-02-17 The Gillette Company Enhanced efficacy antiperspirant compositions containing strontium
DE102005012476A1 (de) 2005-03-16 2006-09-21 Henkel Kgaa Inhibitoren von Staphylococcus hominis in Deodorantien und Antitranspirantien
WO2007071474A1 (fr) 2005-12-16 2007-06-28 Beiersdorf Ag Action longue duree amelioree d'antitranspirants
WO2009012925A2 (fr) * 2007-07-24 2009-01-29 Beiersdorf Ag Formulation cosmétique ou dermatologique contenant de l'acide mandélique d ou l
FR2940062A1 (fr) * 2008-12-19 2010-06-25 Oreal Agent multi composants anti-transpirant comprenant deux composes capables de reagir par interaction physique et procede de traitement de la transpiration humaine en deux etapes
WO2013013999A2 (fr) 2011-07-22 2013-01-31 L'oreal Utilisation, comme anti-transpirant, d'un sel de cation multivalent sans anti-transpirant de type halogénure d'aluminium ou composé apte à réagir avec ledit sel afin de produire un effet anti-transpirant
EP2857482A1 (fr) * 2012-06-01 2015-04-08 Kao Corporation Composition de parfum
WO2015051805A1 (fr) * 2013-10-09 2015-04-16 Riemann Trading Aps Composition antiperspirante améliorée
EP3000459A1 (fr) * 2014-09-29 2016-03-30 Johnson & Johnson Consumer Inc. Compositions anti-transpirantes
DE102014222270A1 (de) 2014-10-31 2016-05-04 Thomas Brunner Hygiene GmbH Kosmetische Antitranspirant-Zusammensetzung
DE102015214143A1 (de) * 2015-07-27 2017-02-02 Beiersdorf Ag Schweiß verringernde kosmetische Zubereitung
DE102015011694A1 (de) * 2015-09-14 2017-03-16 Forschungszentrum Jülich GmbH Reinigungsmittel auf Mikroemulsionsbasis
DE102015226630A1 (de) 2015-12-23 2017-06-29 Beiersdorf Ag Verfahren zur Schweißreduktion

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
"Final Monograph", vol. 68, 2003, article "Antiperspirants Drug Products for Over-the-Counter Human Use"
INT J COSMET SCI, vol. 29, no. 3, June 2007 (2007-06-01), pages 169 - 79
RELLER HH; LUEDDERS WL: "Hemisphere Publishing Company", vol. 4, 1977, article "Advances in Modern Toxicology, Dermatoxicology and Pharmocology", pages: 1 - 5
RELLER; LÜDDERS, PHARMACOLOGIC AND TOXICOLOGIC EFFECTS OF TOPICALLY APPLIED AGENTS ON THE ECCRINE SWEAT GLANDS, vol. 4, 1975, pages 18
SHELLEY WB; HURLEY HJ, ACTA. DERM. VENEREOL., vol. 55, 1975, pages 241 - 60

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3866935B1 (fr) 2018-10-18 2022-08-10 Unilever Global Ip Limited Procédé de réduction de la transpiration
AU2019376458B2 (en) * 2018-11-06 2023-05-04 Unilever Global Ip Limited Antiperspirant compositions
EP3876900B1 (fr) * 2018-11-06 2024-05-01 Unilever Global Ip Limited Compositions anti-transpirantes
DE102020207685A1 (de) 2020-06-22 2021-12-23 Beiersdorf Aktiengesellschaft Kosmetische Zubereitung umfassend schweißhemmende anorganische Salze, Carbonsäuren und 1,3-Propandiol
WO2021259557A1 (fr) 2020-06-22 2021-12-30 Beiersdorf Ag Préparation cosmétique comprenant des sels inorganiques anti-transpirants, des acides carboxyliques et du 1,3-propanediol
WO2022122598A1 (fr) 2020-12-07 2022-06-16 Unilever Ip Holdings B.V. Compositions antitranspirantes

Also Published As

Publication number Publication date
BR112020018031A2 (pt) 2020-12-22
AU2019259299A1 (en) 2020-11-12
EP3784203A1 (fr) 2021-03-03
DE102018206624A1 (de) 2019-10-31

Similar Documents

Publication Publication Date Title
WO2019206466A1 (fr) Préparation à action anti-transpirante comprenant des sels de métal alcalino-terreux et des acides carboxyliques
EP2782645B1 (fr) Utilisation de caprylates/caprates d'isosorbide dans des déodorants et des anti-transpirants
EP3393427B1 (fr) Procédé de réduction de la transpiration
EP2934459B1 (fr) Protection améliorée contre l'odeur corporelle
EP3328502A1 (fr) Antitranspirant
EP4051218A1 (fr) Préparation cosmétique comprenant des sels de métaux alcalino-terreux, des acides carboxyliques et des émulsifiants à chaînes hydrophobes ramifiées
EP3328348A1 (fr) Préparation cosmétique permettant de réduire la formation de sueur
EP3328346A1 (fr) Préparation cosmétique réduisant la transpiration
EP3784206A1 (fr) Préparation à action anti-transpirante comprenant des sels de métal alcalino-terreux
DE102020125876A1 (de) Zusammensetzung zur Behandlung von Haaren und der Kopfhaut
EP4167931A1 (fr) Préparation cosmétique comprenant des sels inorganiques anti-transpirants, des acides carboxyliques et du 1,3-propanediol
EP3793509A1 (fr) Procédé de réduction de sueur à l'acide malonique
EP3328505B1 (fr) Antisudoral
DE102016000191A1 (de) Schweißreduzierende Zubereitung umfassend Hydroxycarbonsäuren und Polyquaternium Polymere
EP3793693A1 (fr) Préparation active antitranspirante sans eau
WO2017016859A1 (fr) Antitranspirant
DE102015214145A1 (de) Schweiß verringernde kosmetische Zubereitung
DE2161551A1 (de) Zwei-Komponenten-Antitranspirant

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 19700920

Country of ref document: EP

Kind code of ref document: A1

REG Reference to national code

Ref country code: BR

Ref legal event code: B01A

Ref document number: 112020018031

Country of ref document: BR

NENP Non-entry into the national phase

Ref country code: DE

ENP Entry into the national phase

Ref document number: 2019259299

Country of ref document: AU

Date of ref document: 20190116

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 2019700920

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 112020018031

Country of ref document: BR

Kind code of ref document: A2

Effective date: 20200903