EP3554540C0 - Behandlung von erkrankungen des gastrointestinaltraktes mit einem il-12/il-23 inhibitor mit freisetzung anhand einer essbaren vorrichtung - Google Patents

Behandlung von erkrankungen des gastrointestinaltraktes mit einem il-12/il-23 inhibitor mit freisetzung anhand einer essbaren vorrichtung

Info

Publication number
EP3554540C0
EP3554540C0 EP17826641.7A EP17826641A EP3554540C0 EP 3554540 C0 EP3554540 C0 EP 3554540C0 EP 17826641 A EP17826641 A EP 17826641A EP 3554540 C0 EP3554540 C0 EP 3554540C0
Authority
EP
European Patent Office
Prior art keywords
treatment
gastrointestinal diseases
release inhibitor
edible
edible release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP17826641.7A
Other languages
English (en)
French (fr)
Other versions
EP3554540B1 (de
EP3554540A1 (de
Inventor
Mitchell Lawrence Jones
Sharat Singh
Christopher Loren Wahl
Harry Stylli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biora Therapeutics Inc
Original Assignee
Biora Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biora Therapeutics Inc filed Critical Biora Therapeutics Inc
Publication of EP3554540A1 publication Critical patent/EP3554540A1/de
Application granted granted Critical
Publication of EP3554540B1 publication Critical patent/EP3554540B1/de
Publication of EP3554540C0 publication Critical patent/EP3554540C0/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
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    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K9/0009Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241Tumor Necrosis Factors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
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    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
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    • A61B10/0045Devices for taking samples of body liquids
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    • AHUMAN NECESSITIES
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    • A61K9/0097Micromachined devices; Microelectromechanical systems [MEMS]; Devices obtained by lithographic treatment of silicon; Devices comprising chips
    • CCHEMISTRY; METALLURGY
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    • G01N2333/52Assays involving cytokines
    • G01N2333/555Interferons [IFN]
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Microbiology (AREA)
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  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
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  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
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EP17826641.7A 2016-12-14 2017-12-14 Behandlung von erkrankungen des gastrointestinaltraktes mit einem il-12/il-23 inhibitor mit freisetzung anhand einer essbaren vorrichtung Active EP3554540B1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662434348P 2016-12-14 2016-12-14
US201762478744P 2017-03-30 2017-03-30
US201762545188P 2017-08-14 2017-08-14
US201762583797P 2017-11-09 2017-11-09
PCT/US2017/066474 WO2018112232A1 (en) 2016-12-14 2017-12-14 Treatment of a disease of the gastrointestinal tract with an il-12/il-23 inhibitor released using an ingestible device

Publications (3)

Publication Number Publication Date
EP3554540A1 EP3554540A1 (de) 2019-10-23
EP3554540B1 EP3554540B1 (de) 2023-08-02
EP3554540C0 true EP3554540C0 (de) 2023-08-02

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Application Number Title Priority Date Filing Date
EP17826641.7A Active EP3554540B1 (de) 2016-12-14 2017-12-14 Behandlung von erkrankungen des gastrointestinaltraktes mit einem il-12/il-23 inhibitor mit freisetzung anhand einer essbaren vorrichtung

Country Status (10)

Country Link
US (2) US11597762B2 (de)
EP (1) EP3554540B1 (de)
JP (2) JP7237834B2 (de)
KR (1) KR20190095931A (de)
CN (2) CN110072551B (de)
AU (1) AU2017376807B2 (de)
BR (1) BR112019011702A2 (de)
CA (1) CA3045475A1 (de)
MX (1) MX2019006823A (de)
WO (1) WO2018112232A1 (de)

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CA3085330A1 (en) * 2017-12-14 2019-06-20 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with a s1p modulator
JP6611833B2 (ja) * 2018-01-16 2019-11-27 キヤノン株式会社 放射線撮影システム、並びに、カメラ制御装置及びその制御方法
EP3810268A1 (de) * 2018-06-20 2021-04-28 Progenity, Inc. Behandlung einer erkrankung des magen-darm-traktes mit einem il-12/il-23-inhibitor
BR112021005467A2 (pt) * 2018-09-24 2021-06-22 Janssen Biotech, Inc. método seguro e eficaz para tratar colite ulcerativa com anticorpo anti-il12/il23
AU2019378008A1 (en) * 2018-11-15 2021-06-03 Janssen Biotech, Inc. Methods and compositions for prediction of response to a therapy of an inflammatory bowel disease
CN109350599A (zh) * 2018-12-12 2019-02-19 辽宁新高制药有限公司 一种用于皮肤念球菌病治疗的喷雾剂
CN113874073A (zh) 2019-05-23 2021-12-31 詹森生物科技公司 用针对IL-23和TNFα的抗体的联合疗法治疗炎性肠病的方法
WO2021074897A2 (en) * 2019-10-18 2021-04-22 Janssen Biotech, Inc. Safe and effective method of treating ulcerative colitis with anti-il12/il23 antibody
CN115103636A (zh) * 2019-12-16 2022-09-23 伊莱利利公司 胃肠取样胶囊
KR102391865B1 (ko) * 2020-04-03 2022-04-27 재단법인대구경북과학기술원 약물 전달 디바이스
CN115768466A (zh) 2020-05-21 2023-03-07 詹森生物科技公司 用抗IL-23和TNFα抗体的联合疗法治疗炎性肠病的方法
CN112731954B (zh) * 2020-12-25 2024-06-21 深圳市优必选科技股份有限公司 机器人的运动控制方法、装置、机器人及存储介质
US20240316324A1 (en) * 2021-01-29 2024-09-26 Biograil ApS Drug delivery device with releasable attachment part
DK180991B1 (en) * 2021-01-29 2022-09-06 Biograil ApS Drug delivery device with carrier and insert
IL303862A (en) * 2021-01-29 2023-08-01 Biograil ApS Single attachment part drug delivery device
MX2024005195A (es) * 2021-10-28 2024-05-14 Biograil ApS Dispositivo de administracion de farmacos en dosis altas.
EP4197437A1 (de) * 2021-12-17 2023-06-21 Stichting IMEC Nederland Verfahren und vorrichtungen zur in-vivo-bewertung von analyten im magen-darm-trakt
WO2024086013A1 (en) * 2022-10-17 2024-04-25 Rani Therapeutics, Llc Ustekinumab dosage forms and methods
CN116027048A (zh) * 2023-02-06 2023-04-28 山东中鸿特检生物科技有限公司 一种细胞因子风暴综合征诊断试剂盒及其应用
WO2025235985A1 (en) * 2024-05-10 2025-11-13 University Of Southern California Ingestible sensor or treatment system and method with localization from magnetic-field generating wearable device

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