EP3362092A1 - Herstellung und verwendung von personalisiertem hyperimmunem ei in der psoriasis-behandlung - Google Patents

Herstellung und verwendung von personalisiertem hyperimmunem ei in der psoriasis-behandlung

Info

Publication number
EP3362092A1
EP3362092A1 EP16716713.9A EP16716713A EP3362092A1 EP 3362092 A1 EP3362092 A1 EP 3362092A1 EP 16716713 A EP16716713 A EP 16716713A EP 3362092 A1 EP3362092 A1 EP 3362092A1
Authority
EP
European Patent Office
Prior art keywords
igy
patient
chickens
specific
psoriasis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP16716713.9A
Other languages
English (en)
French (fr)
Inventor
Chiurciu CONSTANTIN
Chiurciu VIORICA
Lucica SIMA
Iuliana MIHAI
Victor Patrascu Ionel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Romvac Co SA
Original Assignee
Romvac Co SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Romvac Co SA filed Critical Romvac Co SA
Publication of EP3362092A1 publication Critical patent/EP3362092A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/02—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from eggs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration

Definitions

  • Ab2a and Ab2 ⁇ Two types of Ab2, namely Ab2a and Ab2 ⁇ , if Ab2 was capable of binding to Abl in the presence of the antigen.
  • the anti idiotypic antibody Ab2p does not bind to Abl in the excessive presence of the antigen, maybe because Ab2 binds with the binding sites of Abl .
  • the anti-idiotypic Ab2a antigens binds with an idiotype distinct from the Abl antigen site.
  • chickens are actively immunized with antigenic stimuli prepared for this purpose.
  • the chicken immune response is found in blood and yolk of eggs which are collected after the antibody level can be detected in blood.
  • the pathological material used for the rapid immunization of chickens in order to obtain an appropriate specific immune response (1,500 OD or higher by ELISA) is used in vitro and for the isolation, identification and description of various microorganisms existing in this product.
  • This activity, including the antibiogram, contributes to the description of psoriasis wound infections in the patient.
  • the specific anti psoriasis activity of IgY is determined by a quantitative method against the antigen represented by the inactivated and freeze-dried pathological material.
  • FIG. 8 Evolution of wounds on the upper right arm after administering personalized IgY; (A) Photo taken at the beginning of treatment and (B) Photo taken after 19 days of treatment

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
EP16716713.9A 2015-10-16 2016-01-08 Herstellung und verwendung von personalisiertem hyperimmunem ei in der psoriasis-behandlung Pending EP3362092A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ROA201500735A RO130965A8 (ro) 2015-10-16 2015-10-16 Producerea şi utilizarea oului hiperimun personalizat () în tratamentul psoriazisului
PCT/RO2016/000002 WO2017065626A1 (en) 2015-10-16 2016-01-08 Manufacture and use of personalized hyperimmune egg in psoriasis treatment

Publications (1)

Publication Number Publication Date
EP3362092A1 true EP3362092A1 (de) 2018-08-22

Family

ID=55754390

Family Applications (1)

Application Number Title Priority Date Filing Date
EP16716713.9A Pending EP3362092A1 (de) 2015-10-16 2016-01-08 Herstellung und verwendung von personalisiertem hyperimmunem ei in der psoriasis-behandlung

Country Status (4)

Country Link
EP (1) EP3362092A1 (de)
MA (1) MA42973A (de)
RO (1) RO130965A8 (de)
WO (1) WO2017065626A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RO132299A3 (ro) * 2017-06-06 2018-12-28 Fântână Raul Sorin Compoziţie şi metodă de preparare şi evaluare a unui imunogen complex numit i-spga, destinat producerii de proteine imunologic active ()
US11319382B1 (en) 2021-06-28 2022-05-03 King Abdulaziz University Methods for producing and using IgY antibodies targeting the middle east respiratory syndrome coronavirus spike protein to treat or prevent MERS-CoV infection

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1068524C (zh) * 1997-06-23 2001-07-18 叶庆炜 一种治疗顽症牛皮癣的药物
AU2115799A (en) * 1998-01-19 1999-08-02 Dcv, Inc. Composition and method for treatment and prevention of arthritis and/or autoimmune diseases
JP2002532066A (ja) * 1998-11-16 2002-10-02 ジェンウェイ バイオテック， インコーポレイテッド 鳥類におけるポリヌクレオチドワクチンを用いる抗体の産生
CN101626784B (zh) * 2006-08-31 2013-07-17 作为康可信托公司受托人的A.C.N.135493391股份有限公司 利用包含抗体的组合物治疗和/或预防非传染性医学病症
JP2010536932A (ja) * 2007-08-30 2010-12-02 ベンクト・オーゲルプ 真菌感染を治療および予防するための、ニワトリ卵黄免疫グロブリン（ＩｇＹ）の局所投与
JP5439127B2 (ja) * 2009-11-13 2014-03-12 株式会社さいわいメディカル 乾癬又はアトピー性皮膚炎治療剤
RO129645B1 (ro) * 2014-02-25 2022-05-30 Romvac Company S.A. PROCEDEU DE OBŢINERE A IMUNOGLO- BULINELOR IgY
RO130213A8 (ro) * 2014-10-29 2017-06-30 Romvac Company S.A. Producerea şi folosirea oului hiperimun - pc2

Also Published As

Publication number Publication date
RO130965A0 (ro) 2016-03-30
RO130965A8 (ro) 2017-06-30
WO2017065626A1 (en) 2017-04-20
MA42973A (fr) 2018-08-22

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