EP2830582A2 - Dentifrice possédant une rhéologie améliorée - Google Patents

Dentifrice possédant une rhéologie améliorée

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Publication number
EP2830582A2
EP2830582A2 EP13706948.0A EP13706948A EP2830582A2 EP 2830582 A2 EP2830582 A2 EP 2830582A2 EP 13706948 A EP13706948 A EP 13706948A EP 2830582 A2 EP2830582 A2 EP 2830582A2
Authority
EP
European Patent Office
Prior art keywords
weight
glycerol
sorbitol
xanthan
dental care
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP13706948.0A
Other languages
German (de)
English (en)
Inventor
Thomas Welss
Wilfried Howorka
Benedikt Schmitz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Henkel AG and Co KGaA
Original Assignee
Henkel AG and Co KGaA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Henkel AG and Co KGaA filed Critical Henkel AG and Co KGaA
Publication of EP2830582A2 publication Critical patent/EP2830582A2/fr
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A61K2800/592—Mixtures of compounds complementing their respective functions
    • A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18

Definitions

  • the invention relates to a toothpaste having a rheology that promotes plaque reduction and fluoride deposition and also accommodates the particular requirements of using electric toothbrushes.
  • Dentifrices are available in various forms on the market and are primarily used to clean the tooth surface and to prevent tooth and gum disease. They usually contain a combination of polishes, humectants, surfactants, binders, flavorings and fluoride-containing and antimicrobial agents. In addition to toothpowder, which play a minor role because of their increased abrasiveness, dentifrices are mainly offered in paste, cream and translucent or transparent gel form. Liquid or liquid toothpastes and mouthwashes have also become increasingly important in recent years.
  • Electrically moving brush heads are customary in various designs. Thus, there are round brush heads which are electrically rotated in rotation or partial rotation with rotations clockwise and counterclockwise. But there are also elongated, the conventional toothbrush modeled brush heads, which oscillate electrically.
  • the rheology of the dentifrice plays an important role:
  • the composition must be sufficiently viscous to be applied to the brush head, while brushing but they quickly give an application mixture in the oral cavity, the effective PIaquereduzi für a high Fluoride deposition allows what is usually more effective to realize with low viscosity compositions.
  • Another area of responsibility is the provision of products that solve the tasks assigned to them with as little raw material as possible, in order to save resources and to provide ecologically compatible products.
  • the reduction of synthetic ingredients is therefore another important task in the formulation of cosmetic products.
  • the present invention therefore an object of the invention to provide a mouth and Zahnfit- and -curisstoff that solves the above-mentioned tasks and is sufficiently viscous to be applied to brush heads conventional or electric toothbrushes, but it is sufficiently low viscosity to to allow effective reduction of PIaquer and high fluoride deposition.
  • the formulations should contain as few synthetic ingredients as possible.
  • compositions with low humectant levels can be thickened with certain amounts of xanthan so as to achieve an optimum compromise between applicability and piquer reduction and fluoride deposition, respectively.
  • these compositions are particularly suitable for cleaning by means of electric toothbrushes, as they protect the delicate mechanics of electrically operated brush heads.
  • the amounts of certain humectants are selected within narrow limits.
  • the present invention is in a first embodiment, an oral and dental care and cleaning compositions containing - based on its weight - a) 1 to 10 wt .-% sorbitol
  • Oral and dental care products as well as mouth and tooth cleaning agents in the sense of the invention are mouthwashes and toothpowder, oral and toothpastes, liquid mouthwashes and toothpastes as well as oral and dental gels.
  • suitable are toothpastes and liquid dentifrices.
  • they are present as more or less flowable or plastic toothpastes, as they are used to clean the teeth using a toothbrush.
  • compositions according to the invention contain at least 1% by weight of sorbitol.
  • Preferred agents according to the invention contain at least 1.5% by weight of sorbitol, preferably at least 2% by weight of sorbitol, more preferably at least 3% by weight of sorbitol and in particular at least 4% by weight of sorbitol.
  • Very particularly preferred compositions contain, based on their weight, 4.5 to 9.5% by weight of sorbitol, more preferably 5 to 9% by weight of sorbitol, even more preferably 5.5 to 8.5% by weight of sorbitol, more preferably 6 to 8 wt .-% sorbitol and in particular 6.5 to 7.5 wt .-% sorbitol. All amounts are based on 100% sorbitol, i. If a sorbitol solution is used, the actual sorbitol content should be used.
  • compositions of the invention further contain at least 1 wt .-% glycerol.
  • Preferred agents according to the invention comprise at least 1.5% by weight of glycerol, preferably at least 2% by weight of glycerol, particularly preferably at least 2.5% by weight of glycerol and in particular at least 3% by weight of glycerol.
  • Very particularly preferred compositions contain, based on their weight, 1, 5 to 4.9% by weight of glycerol, more preferably 1.75 to 4.8% by weight of glycerol, even more preferably 2 to 4.7% by weight of glycerol , Particularly preferably 2.25 to 4.6 wt .-% glycerol and in particular 2.5 to 4.5 wt .-% glycerol. All amounts are based on 100% glycerol, i. If a glycerol solution is used, the actual glycerol content should be taken as the basis.
  • compositions of the invention may contain other humectants, with 1,2-propylene glycol being a preferred further humectant.
  • Preferred agents according to the invention contain humectants in defined quantitative ranges, with particularly preferred oral and dental care and cleaning compositions being characterized in that the total amount of polyhydric alcohols from the group sorbitol and / or glycerol and / or 1, 2 Propylene glycol 2 to 20 wt .-%, preferably 3 to 15 wt .-%, more preferably 4 to 14 wt .-%, even more preferably 5 to 13 wt .-% and in particular 6 to 12 wt .-% is.
  • the agents according to the invention are preferably water-based and preferably contain at least 40% by weight of water.
  • Preferred oral and dental care and cleaning compositions according to the invention contain from 40 to 84% by weight, preferably from 45 to 80% by weight, more preferably from 50 to 75% by weight, even more preferably from 55 to 70% by weight and in particular 57.5 to 65% by weight of water.
  • compositions of the invention results from a low content of humectants, combine with defined amounts of a certain thickener, wherein xanthan gum is used according to the invention.
  • the compositions of the invention contain from 0.1 to 1% by weight of xanthan, with preferred oral and dental care and cleaning compositions according to the invention being characterized in that they contain from 0.1 to 7.5% by weight, preferably from 0.25 to 5% Wt .-%, more preferably 0.5 to 2.5 wt .-% and in particular 0.6 to 1, 5 wt .-% xanthan.
  • moisturizers and polishes are used in certain proportions to each other.
  • Particularly preferred rheological properties can be achieved with mouth and dental care and cleaning compositions according to the invention, in which the weight ratio of humectant (s) to xanthan is in the range> 8 to ⁇ 20, preferably in the range> 8.5 to ⁇ 17.5 preferably in the range> 9 to ⁇ 15 and in particular in the range> 9 to ⁇ 12.5.
  • % Of xanthan 5 to 7.5% by weight of sorbitol and 2 to 4.7% by weight of glycerol and 0.1 to 1% by weight of xanthan, 5 to 7.5% by weight of sorbitol and 2.25 to 4.6% by weight of glycerol and 0.1 to 1% by weight of xanthan, 5 to 7.5% by weight of sorbitol and 2.5 to 4.5% by weight of glycerol and 0 , 1 to 1 wt .-% xanthan., 5 to 9.5 wt .-% sorbitol and 1, 5 to 4.9 wt .-% glycerol and 0.1 to 7.5 wt .-% xanthan., 5 to 9.5 wt .-% sorbitol and from 1, 75 to 4.8 wt .-% glycerol and 0, 1 to 7.5 wt .-% xanthan, 5 to 9.5 wt .-% sorbitol
  • % Xanthan. 5 to 7.5% by weight of sorbitol and 2 to 4.7% by weight of glycerol and 0.25 to 5% by weight of xanthan., 5 to 7.5% by weight of sorbitol and 2.25 to 4.6% by weight of glycerin and 0.25 to 5% by weight of xanthan gum, 5 to 7.5% by weight of sorbitol and 2.5 to 4.5% by weight of glycerol and 0 , 25 to 5 wt .-% xanthan., 5 to 9.5 wt .-% sorbitol and 1, 5 to 4.9 wt .-% glycerol and 0.5 to 2.5 wt .-% xanthan., 5 to 9.5% by weight sorbitol and from 1.75 to 4.8% by weight glycerol and from 0.5 to 2.5% by weight xanthan, from 5 to 9.5% by weight sorbitol and from 2 to 4 , 7 wt .-% g
  • compositions of the invention preferably contain at least one polishing agent.
  • a polishing agent are in principle all known for toothpastes friction body, in particular those that do not contain calcium ions.
  • suitable polishing agent components are therefore silicic acids, aluminum hydroxide, aluminum oxide, sodium aluminum silicates, organic polymers or mixtures of such friction bodies.
  • Calcium containing polishing components such as e.g.
  • chalk, calcium pyrophosphate, dicalcium phosphate dihydrate can be present in amounts of up to 5% by weight, based on the total composition.
  • the total content of polishing agents is preferably in the range of 5 to 50% by weight of the dentifrice.
  • Agents preferred according to the invention contain polishing agents within narrower ranges.
  • preferred oral and Zahnfax- and - cleaning agent according to the invention characterized in that they 1 to 25 wt .-%, preferably 2.5 to 20% by weight, more preferably 5 to 18 wt .-% and in particular 7.5 contain up to 16 wt .-% polish.
  • Toothpastes and liquid dentifrices containing silicic acids as a polishing agent are particularly preferred.
  • Suitable silicas are e.g. Gel silicas, hydrogel silicas and precipitated silicas.
  • Gel silicas are prepared by reacting sodium silicate solutions with strong, aqueous mineral acids to form a hydrosol, aging to the hydrogel, washing and drying. If the drying takes place under mild conditions to water contents of 15 to 35 wt .-%, the so-called hydrogel silicas are obtained. Drying to water contents below 15% by weight results in an irreversible shrinkage of the previously loose structure of the hydrogel to the dense structure of the so-called xerogel.
  • a second, preferably suitable group of silica polishing agents are the precipitated silicas. These are obtained by precipitation of silica from dilute alkali silicate solutions by addition of strong acids under conditions in which aggregation to the sol and gel can not occur.
  • Suitable methods for preferably suitable is a precipitated silica having a BET surface area of 15 to 10 m 2 / g, a particle size of 0.5 to 20 ⁇ m, where at least 80% by weight of the primary particles are below 5 ⁇ m, and one Viscosity in 30% glycerol-water (1: 1) dispersion of 30 - 60 Pa.s (20 ° C) in an amount of 10 - 20 wt .-% of the toothpaste.
  • Particularly suitable precipitated silicas of this type have rounded corners and edges and are commercially available under the trade name ® Sident 12 DS (DEGUSSA).
  • Such toothpastes are therefore preferably used in addition to the mentioned precipitated silicas, even more finely divided, so-called thickening silicas having a BET surface area of 150-250 m 2 / g, for example the commercial products Sipernat 22 LS or Sipernat ® 320 DS.
  • polishing agent component e.g. Aluminum oxide in the form of slightly calcined clay containing - and -Aluminiumoxid in an amount of about 1-5% by weight.
  • Aluminum oxide in the form of slightly calcined clay containing - and -Aluminiumoxid in an amount of about 1-5% by weight.
  • a suitable alumina is available under the trade designation "Polianton earth P10 finest" (Giulini Chemie).
  • polishing agent As a polishing agent are all further known for toothpastes friction body such.
  • oral and dental care and cleaning compositions according to the invention are preferred, which additionally cleaning body, preferably silicas, aluminum hydroxide, alumina, calcium pyrophosphate, chalk, dicalcium phosphate dihydrate (CaHP0 4 -2H 2 0), sodium aluminum silicates, especially zeolite A, organic polymers, in particular Polymethacrylates or mixtures of these friction bodies, preferably in amounts of 1 to 30 wt.%, Preferably from 2.5 to 25 wt.% And in particular from 5 to 22 wt.%, Each based on the total agent.
  • cleaning body preferably silicas, aluminum hydroxide, alumina, calcium pyrophosphate, chalk, dicalcium phosphate dihydrate (CaHP0 4 -2H 2 0), sodium aluminum silicates, especially zeolite A, organic polymers, in particular Polymethacrylates or mixtures of these friction bodies, preferably in amounts of 1 to 30 wt.%, Preferably from 2.5 to 25 wt.% And in particular
  • mouth and Zahnux- and -therapiesmittel contain exclusively polishes from the group of silicas, aluminum hydroxide, alumina, dicalcium phosphate dihydrate (CaHP0 4 -2H 2 0) or mixtures of these friction. These polishing agents have proven to be particularly efficient in achieving the object of the invention.
  • Preferred oral and dental care and cleaning compositions according to the invention are characterized in that they contain from 5 to 25% by weight, preferably from 7.5 to 22.5% by weight, more preferably from 10 to 20% by weight and in particular 12.5 to 18 wt .-% polishes from the group of silicas, aluminum hydroxide, alumina, dicalcium phosphate dihydrate (CaHP0 4 -2H 2 0) or mixtures of these friction bodies containing.
  • the compositions according to the invention contain 1 to 30% by weight of precipitated silica (s) with a specific surface area according to ISO 5794-1, Appendix D of ⁇ 55 m 2 / g, based on their weight.
  • the precipitated silicas having corresponding specific surface areas are used within narrower ranges of amounts, and particularly preferably precipitated silicas are used which have even lower specific surface areas according to ISO 5794-1, Annex D.
  • Preferred oral and dental care and cleaning compositions according to the invention contain from 2.5 to 25% by weight, preferably from 5 to 20% by weight, more preferably from 7.5 to 17.5% by weight, more preferably from 8.0 to 15.0 wt .-% and in particular 10.0 to 13.0 wt .-% precipitated silica (s) having a specific surface area according to ISO 5794-1, Annex D of ⁇ 55 m 2 / g.
  • Particularly preferred mouth and dental care and cleaning agents according to the invention are characterized in that all precipitated silica contained in the middle have a specific surface area according to ISO 5794-1, Annex D of ⁇ 53 m 2 / g, preferably of ⁇ 51 m 2 / g , more preferably of ⁇ 49 m 2 / g and in particular of ⁇ 47 m 2 / g.
  • the precipitated silicas used are characterized by further physical parameters.
  • Preferably precipitated silicas to be used have tamped densities> 360 g / l (measured according to ISO 787-1 1), more preferably> 375 g / l, more preferably> 400 g / l and in particular> 425 g / l.
  • precipitated silicas which have a DBP absorption according to DIN 53601 of less than 140 g / 100 g.
  • Very particularly preferred precipitated silicas to be used according to the invention have a DBP absorption according to DIN 53601 of less than 135 g / 100 g, preferably of a DBP absorption according to DIN 53601 of less than 130 g / 100 g and in particular less than 125 g / 100 g on.
  • compositions according to the invention contain from 2.5 to 25% by weight, preferably from 5 to 20% by weight, particularly preferably from 7.5 to 17.5% by weight, more preferably from 8.0 to 15.0% by weight. % and in particular 10.0 to 14.0 wt .-% precipitated silica (s) having a specific surface area according to ISO 5794-1, Annex D of ⁇ 45 m 2 / g and a tamped density (measured according to ISO 787-1 1), of> 425 g / l.
  • Further preferred agents according to the invention contain from 2.5 to 25% by weight, preferably from 5 to 20% by weight, particularly preferably from 7.5 to 17.5% by weight, more preferably from 8.0 to 15.0% by weight. % and in particular 10.0 to 14.0 wt .-% precipitated silica (s) having a specific surface area after ISO 5794-1, Annex D of ⁇ 45 m 2 / g and a DBP absorption according to DIN 53601 of less than 125 g / 100 g.
  • Particularly preferred agents according to the invention contain from 2.5 to 25% by weight, preferably from 5 to 20% by weight, particularly preferably from 7.5 to 17.5% by weight, more preferably from 8.0 to 15.0% by weight. % and in particular 10.0 to 14.0 wt .-% precipitated silica (s) having a specific surface according to ISO 5794-1, Annex D of ⁇ 45 m 2 / g and a tamped density (measured according to ISO 787-1 1), of> 425 g / l and a DBP absorption according to DIN 53601 of less than 125 g / 100 g.
  • the agents according to the invention may contain surfactant (s).
  • surfactants are also preferably used within narrow ranges, so that preferred oral and dental care and cleaning compositions according to the invention are characterized in that they contain from 0.5 to 5% by weight, preferably from 0.75 to 4.5% by weight, more preferably 1 to 4 wt .-%, still more preferably 1, 25 to 3.5 wt .-% and in particular 1, 6 to 2.5 wt .-% surfactant (s) included.
  • Suitable surfactants are, for. B. linear sodium alkyl sulfates having 12-18 C atoms in the alkyl group. These substances additionally have an enzyme-inhibiting effect on the bacterial metabolism of the dental plaque.
  • Other suitable surfactants are alkali metal salts, preferably sodium salts of sulfonate Alkylpolyglycolethersulfat with 12-16 C atoms in the linear alkyl group and 2-6 glycol ether groups in the molecule, of linear alkane (C 2 -C 8), Sulfobernsteinklamonoalkyl (C 2 -C 8 ) esters, of sulfated fatty acid monoglycerides, sulfated fatty acid alkanolamides, sulfoacetic acid alkyl (Ci 2 -C 6 ) esters, acylsarcosines, acyl taurides and acyl isothionates each having 8-18 C atoms in the acyl group.
  • zwitterionic, ampholytic and nonionic surfactants are suitable, for.
  • a preferred group of surfactants to be used are the anionic surfactants.
  • Mouth and dental care and cleaning agents preferred according to the invention are characterized in that they contain from 0.25 to 4% by weight, preferably from 0.5 to 3.5% by weight, further preferably 0.75 to 3 wt .-%, still more preferably 1 to 2.5 wt .-% and in particular 1, 6 to 2.2 wt .-% anionic (s) surfactant (s) included.
  • anionic surfactants are soaps, alkylbenzenesulfonates, alkanesulfonates, olefinsulfonates, alkyl ether sulfonates, glycerol ether sulfonates, ⁇ -methyl ester sulfonates, sulfofatty acids, alkyl sulfates, fatty alcohol ether sulfates, glycerol ether sulfates, hydroxy mixed ether sulfates, monoglyceride (ether) sulfates, fatty acid amide (ether) sulfates, mono- and dialkyl sulfosuccinates, mono- and dialkyl sulfosuccinamates, sulfotriglycerides, amide soaps, ether carboxylic acids and their salts, Fatty acid isethionates, fatty acid sarcosinates, fatty acid taurides, N-acylamin
  • Very particularly preferred agents according to the invention contain alkyl sulfate (s) as anionic surfactant.
  • mouth and Zahnthro- and - cleaning agents are characterized in that they 0.25 to 4 wt .-%, preferably 0.5 to 3.5 wt .-%, more preferably 0.75 to 3 wt. -%, even more preferably 1 to 2.5 wt .-% and in particular 1, 6 to 2.2 wt .-% sodium dodecyl sulfate included.
  • the agents according to the invention contain, in addition or as an alternative to the anionic surfactants, amphoteric surfactant (s).
  • Ampholytic surfactants and emulsifiers are surface-active compounds which, apart from a C 8 - contain at least one free amino group and at least one -COOH or -S0 3 H group and acyl group capable of forming inner salts - C 2 4 - alkyl or are.
  • ampholytic surfactants are N-alkylglycines, N-alkylaminopropionic acids, N-alkylaminobutyric acids, N-alkylimino-dipropionic acids, N-hydroxyethyl-N-alkylamidopropylglycines, N-alkyltaurines, N-alkylsarcosines, 2-alkylaminopropionic acids and alkylaminoacetic acids each having about 8 to 24 C atoms in the alkyl group.
  • Particularly preferred ampholytic surfactants are N-cocoalkylaminopropionate, cocoacylaminoethylaminopropionate and the d 2 -C 8 -acylsarcosine.
  • Particularly preferred mouth and dental care and cleaning agents according to the invention are characterized in that they contain 0.01 to 2% by weight, preferably 0.05 to 1.5% by weight, more preferably 0.1 to 1% by weight. %, even more preferably 0, 12 to 0.7 wt .-% and in particular 0, 15 to 0.6 wt .-% amphoteric (s) surfactant (s) included.
  • 0.01 to 2% by weight preferably 0.05 to 1.5% by weight, more preferably 0.1 to 1% by weight. %, even more preferably 0, 12 to 0.7 wt .-% and in particular 0, 15 to 0.6 wt .-% amphoteric (s) surfactant (s) included.
  • Particularly preferred mouth and dental care and cleaning agents according to the invention are characterized in that they contain amphoteric surfactant (s) from the groups of
  • 2-Alkylaminopropion Acid each having about 8 to 24 carbon atoms in the alkyl group
  • Alkylaminoacetic acids each having about 8 to 24 carbon atoms in the alkyl group
  • N-alkyl-N, N-dimethylammonium glycinates for example cocoalkyldimethylammonium glycinate,
  • N-acylaminopropyl-N, N-dimethylammonium glycinates for example cocoacylaminopropyl-dimethylammonium glycinate,
  • Particularly preferred oral and dental care and cleaning agents contain as amphoteric surfactants betaines of the formula (Bet-I)
  • R is a straight-chain or branched, saturated or mono- or polyunsaturated alkyl or alkenyl radical having 8 to 24 carbon atoms.
  • surfactants are referred to the INCI nomenclature as Amidopropylbetaine, wherein the representatives derived from coconut fatty acids are preferred and are referred to as Cocoamidopropylbetaine. According to the invention, particular preference is given to using surfactants of the formula (Bet-I) which are a mixture of the following representatives:
  • the weight ratio of polishing agent (s) to surfactant (s) is ⁇ 6, i. the polishing agents are used at most in 6-fold (weight) excess to the surfactants.
  • the weight ratio is within an even narrower range.
  • Particularly preferred mouth and dental care and cleaning agents are characterized in that the weight ratio of polish (s) to surfactant (s) in the range> 5 to ⁇ 15, preferably in the range> 7.5 to ⁇ 12.5, more preferably in Range> 10 to ⁇ 12 and in particular in the range> 10.25 to ⁇ 1 1, 9 is.
  • Oral and dental care and cleaning agents in particular toothpastes, may e.g. also contain substances that are effective against plaque and / or tartar.
  • Plaque is a rough, sticky deposit on the teeth that consists of saliva, bacteria and food remnants. If mineral salts (for example calcium, phosphate) are released from the saliva in the dental plaque, hard, white or yellowish deposits on the tooth called tartar form. In the porous calculus, in turn, easily deposit plaque that attacks the gums.
  • mineral salts for example calcium, phosphate
  • the bacteria on the tooth surface reduce carbohydrates, especially sugars, from food to acid. This acid dissolves the tooth substance and it comes to tooth decay (tooth rot). In particular, the minerals calcium and phosphate are extracted from the enamel. After the enamel coat also inner layers of the tooth are attacked. Bacteria can invade the dental pulp and cause inflammation there. Usually it comes then to stinging toothache. As already mentioned, plaque contains bacteria, so that antimicrobials are suitable for controlling plaque. These also have an effect as a preservative.
  • E 217) methyl 4-hydroxybenzoate (E 218), methyl 4-hydroxybenzoate, sodium salt (E 219), sulfur dioxide (sulphurous acid), (E 220), sodium sulphite (E 221), sodium bisulphite (E 222), sodium disulphite ( E 223), potassium bisulfite (E 224), calcium sulfite (E 226), calcium hydrogen sulfite (E 227), potassium hydrogen sulfite (E 228), biphenyl (E 230), orthophenylphenol (2-biphenylol), (E 231), sodium orthophenylphenolate (E 232 ), Nisin (E 234), natamycin (E 235), formic acid (E 236), sodium formate (E 237), calcium formate (E 238), hexamethylenetetramine (E 239), dimeth yl dicarbonate (E 242), potassium nitrite (E 249), sodium nitrite (E 250), sodium n
  • Preferred substances are selected from alkypyridinium salts, in particular cetylpyridinium chloride, p-hydroxybenzoic acid methyl, ethyl or propyl ester, sodium sorbate, sodium benzoate, bromochlorophene, triclosan, phenyl salicylic acid ester, biguanides, for example.
  • Chlorhexidine (1,1-hexamethylenebis [5- (4-chlorophenyl) -biguanide), thymol, etc.
  • Oral and dental care and cleaning compositions which are preferred according to the invention are additionally characterized in that they additionally contain antiplaque active substances, preferably alkypyridinium salts, in particular cetylpyridinium chloride, methyl, ethyl or propyl p-hydroxybenzoate, sodium sorbate, sodium benzoate, bromochlorophene, triclosan, hexetidines, phenyl- Salicylic acid esters, biguanides z.
  • antiplaque active substances preferably alkypyridinium salts, in particular cetylpyridinium chloride, methyl, ethyl or propyl p-hydroxybenzoate, sodium sorbate, sodium benzoate, bromochlorophene, triclosan, hexetidines, phenyl- Salicylic acid esters, biguanides z.
  • chlorhexidine thymol, preferably in amounts of 0.05 to 5 wt.%, Preferably from 0, 10
  • Agents preferred according to the invention comprise, for example, 0.1 to 2% by weight, preferably 0.2 to 1.75% by weight, more preferably 0.3 to 1.5% by weight and in particular 0.4 to 1.0 Wt .-% sodium benzoate. Further preferred agents according to the invention are characterized in that they contain from 0.005 to 0, 1 wt .-%, preferably 0.01 to 0.075 wt .-% and in particular 0.02 to 0.05 wt .-% chlorhexidine.
  • Chlorhexidine is preferably used together with alkylpolyglycosides (APG), wherein in preferred agents according to the invention as alkyl glycosides those having 8-18 carbon atoms in the alkyl group and a mean degree of oligomerization of the glycoside of 1-3 in an amount of 0.025 to 2.5 wt. -% are included.
  • APG alkylpolyglycosides
  • Anti-calculus substances may be, for example, chelating agents such.
  • chelating agents such as ethylenediaminetetraacetic acid and its sodium salts, pyrophosphate salts such as the water-soluble dialkali or Tetraalkalimetallpyrophosphat- salts, z. B. Na 4 P 2 0 7 , K4P 2 0 7 , Na 2 K 2 P 2 0 7, Na 2 H 2 P 2 0 7 and K 2 H 2 P 2 0 7 or polyphosphate salts, the z. B. from water-soluble Alkalimethalltripolyphosphaten as sodium tripolyphosphate and potassium tripolyphosphate can be selected.
  • preferred oral and dental care and cleaning agents are characterized in that they additionally phosphate (s), preferably alkali metal phosphate (s) and in particular sodium tripolyphosphate, preferably in amounts of 1 to 10 wt .-%, particularly preferably from 2 to 8 wt .-% and in particular from 3 to 7 wt .-%, each based on the total agent included.
  • phosphate preferably alkali metal phosphate (s) and in particular sodium tripolyphosphate
  • a consistency regulator serve z.
  • natural and / or synthetic water-soluble polymers such as alginates, carrageenan, tragacanth, starch and starch ethers, cellulose ethers such. Carboxymethylcellulose (Na salt), hydroxyethylcellulose, methylhydroxypropylcellulose, guar, acacia, agar, xanthan gum, succinoglycan gum, locust bean gum, pectins, water-soluble carboxyvinyl polymers (e.g., Carbopo D types), polyvinyl alcohol, polyvinylpyrrolidone, Polyethylene glycols, in particular those having molecular weights of 1 500-1 000 000.
  • z. B phyllosilicates
  • montmorillonite clays colloidal thickened silicas such.
  • airgel silicas fumed silicas or finely ground precipitated silicas.
  • viscosity-stabilizing additives from the group of cationic, zwitterionic or ampholytic nitrogenous surfactants, hydroxypropyl-substituted hydrocolloids or polyethylene glycol / polypropylene glycol copolymers having an average molecular weight of 1000 to 5000 or a combination of the compounds mentioned in the toothpastes.
  • the agents according to the invention may also contain substances for increasing the mineralizing potential, for example calcium-containing substances such as, for example, Calcium chloride, calcium acetate and dicalcium phosphate dihydrate.
  • concentration of The calcium-containing substance depends on the solubility of the substance and the interaction with other substances contained in the oral and dental care products.
  • the dentifrices according to the invention may contain further adjuvants and additives known per se.
  • An additive which has been known for a long time as a toothpaste component is particularly effective in the dentifrices according to the invention: calcium glycerophosphate, the calcium salt of glycerol-1-phosphoric acid or glycerol-2-phosphoric acid or the glycerol-1-phosphoric acid enantiomer Glycerol-3-phosphoric acid - or a mixture of these acids.
  • the compound has a remineralizing effect in dentifrices as it provides both calcium and phosphate ions.
  • the dentifrices according to the invention calcium glycerophosphate is preferably used in amounts of 0.01 to 1 wt .-%. Overall, the dentifrices according to the invention may contain customary auxiliaries and additives in amounts of up to 10% by weight.
  • oral and dental care and cleaning agents may more preferably contain anti-caries agents.
  • anti-caries agents may be selected, for example, from organic or inorganic fluorides, for.
  • zinc fluoride, stannous fluoride are preferred.
  • An amount of 0.01-0.2% by weight of fluorine should preferably be present in the form of the compounds mentioned.
  • Oral and dental care and cleaning compositions according to the invention which additionally anti-caries agents, preferably fluorine compound (s), in particular sodium fluoride, potassium fluoride, sodium monofluorophosphate, zinc fluoride, stannous fluoride and sodium fluorosilicate, preferably in amounts of 0.01 to 5 wt.%, Preferably from 0, 1 to 2.5 wt.% And in particular from 0.2 to 1, 1 wt.%, Each based on the total agent, are preferred according to the invention.
  • fluorine compound (s) in particular sodium fluoride, potassium fluoride, sodium monofluorophosphate, zinc fluoride, stannous fluoride and sodium fluorosilicate
  • fluorine compound s
  • sodium fluoride potassium fluoride
  • sodium monofluorophosphate sodium fluoride
  • zinc fluoride stannous fluoride
  • sodium fluorosilicate preferably in amounts of 0.01 to 5 wt.%, Preferably from 0, 1 to 2.5 wt.% And
  • the dentifrices according to the invention may e.g. be improved by the addition of aromatic oils and sweeteners in their organoleptic properties.
  • aroma oils all the natural and synthetic flavors customary for oral and dental care products can be used. Natural flavors can be contained both in the form of natural essential oils isolated from drugs and the individual components isolated therefrom.
  • Suitable flavors are, for example, peppermint oil, spearmint oil, eucalyptus oil, aniseed oil, fennel oil, caraway oil, menthyl acetate, cinnamaldehyde, anethole, vanillin, thymol and mixtures of these components.
  • Suitable sweeteners include saccharin sodium, sodium cyclamate, sucrose, lactose, meltose, fructose and maltose and dextrose.
  • Another object of the present invention is the use of agents according to the invention for cleaning teeth by means of electric toothbrushes.
  • Another object of the present invention is a method for cleaning teeth, characterized in that a composition according to the invention applied to the brush head of an electric toothbrush and brushed with the electric toothbrush teeth.
  • Another object of the present invention is a method for cleaning teeth, characterized by the steps
  • the brush head can be electrically set in motion

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  • Health & Medical Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Emergency Medicine (AREA)
  • Cosmetics (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

La présente invention concerne des produits de soin et de nettoyage pour la bouche et les dents, qui, par rapport à leur poids, contiennent de 1 à 10 % en poids de sorbitol, de 1 à 5 % en poids de glycérine et de 0,1 à 1 % en poids de xanthane, présentent un compromis optimal entre l'aptitude à l'application et la réduction de la plaque ou encore le dépôt de fluorures. En outre, les compositions sont particulièrement appropriées pour le nettoyage au moyen des brosses à dents électriques, car elles ménagent le mécanisme sensible des têtes de brosses entraînées électriquement.
EP13706948.0A 2012-03-30 2013-02-18 Dentifrice possédant une rhéologie améliorée Ceased EP2830582A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE201210205194 DE102012205194A1 (de) 2012-03-30 2012-03-30 Zahncreme mit verbesserter Rheologie
PCT/EP2013/053190 WO2013143782A2 (fr) 2012-03-30 2013-02-18 Dentifrice possédant une rhéologie améliorée

Publications (1)

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EP2830582A2 true EP2830582A2 (fr) 2015-02-04

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EP13706948.0A Ceased EP2830582A2 (fr) 2012-03-30 2013-02-18 Dentifrice possédant une rhéologie améliorée

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Country Link
EP (1) EP2830582A2 (fr)
DE (1) DE102012205194A1 (fr)
WO (1) WO2013143782A2 (fr)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4383987A (en) * 1981-06-26 1983-05-17 Colgate/Palmolive Company Foaming dentifrice containing nonionic surface active agent
US20020031481A1 (en) * 1998-02-27 2002-03-14 Jin Xu Stable herbal dentrifice
US20040131560A1 (en) * 2002-10-04 2004-07-08 The Procter & Gamble Company Oral compositions and use thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
None *
See also references of WO2013143782A2 *

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WO2013143782A2 (fr) 2013-10-03
WO2013143782A3 (fr) 2014-04-24
DE102012205194A1 (de) 2013-10-02

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