EP2696938A2 - Préparations d'aérosol présentant des propriétés de pulvérisation améliorées - Google Patents

Préparations d'aérosol présentant des propriétés de pulvérisation améliorées

Info

Publication number
EP2696938A2
EP2696938A2 EP11805836.1A EP11805836A EP2696938A2 EP 2696938 A2 EP2696938 A2 EP 2696938A2 EP 11805836 A EP11805836 A EP 11805836A EP 2696938 A2 EP2696938 A2 EP 2696938A2
Authority
EP
European Patent Office
Prior art keywords
use according
aerosol
preparation
spray
particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP11805836.1A
Other languages
German (de)
English (en)
Inventor
Annika Scholz
Michael Urban
Heike Miertsch
Stefan Biel
Sabine Ripke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beiersdorf AG
Original Assignee
Beiersdorf AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beiersdorf AG filed Critical Beiersdorf AG
Publication of EP2696938A2 publication Critical patent/EP2696938A2/fr
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/046—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00—Anti-perspirants or body deodorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89—Polysiloxanes
    • A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89—Polysiloxanes
    • A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • A61K8/892—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone modified by a hydroxy group, e.g. dimethiconol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/30—Characterized by the absence of a particular group of ingredients
    • A61K2800/31—Anhydrous

Definitions

  • Aerosol formulations with improved spray properties are provided.
  • the invention includes the use of silicone gums to improve the fragrance
  • aerosol preparation or aerosol product any container made of metal, glass or plastic, including the contained therein, liquefied or dissolved under pressure gas with or without liquid, paste or powder, with a
  • Removal device which makes it possible to leak its contents in the form of suspended in gas solid or liquid particles as foam, paste, powder or in the liquid state.
  • An aerosol is a disperse system in which a solid or liquid is extremely finely dispersed in a gas.
  • the aerosol is usually only when using a suitable spray system by spraying solutions, emulsions or suspensions self-produced, including, for example, spray cans can be used, in which a liquefied compressed gas serves as a propellant gas.
  • spray cans can be used, in which a liquefied compressed gas serves as a propellant gas.
  • aerosol is frequently used by the skilled person also in the sense of aerosol sprays, i.
  • aerosol is understood not to be the pure spray, but a compressed gas packaging together with dispensing or metering device and contents.
  • the contents include active ingredient solution and propellant.
  • the active substance solution is the sum of all the constituents of preparation without the propellant.
  • the term "active substance solution” is also used when the preparation is e.g. in the form of a suspension or emulsion.
  • a suspension is to be understood as a dispersion in which the continuous phase is in the liquid state and the dispersed phase in the solid state.
  • antiperspirants and deodorants (deodorants) are offered in a variety of product forms, with scooters, pump sprayers and aerosols dominating in Europe, and pens in the US, Central and South America. They are both anhydrous (Suspensions) as well as hydrous products (hydro-alcoholic formulations, emulsions) known.
  • Antiperspirants or deodorants are used to eliminate or prevent body odor, which arises when the in itself odorless fresh sweat through
  • Microorganisms is decomposed.
  • the usual cosmetic deodorants are based on different active principles.
  • German-speaking countries - products for use in the underarm area generally referred to as deodorants or "deodorants.” This is irrelevant to the question of whether an antiperspirant effect is present.
  • Volatile silicone oils in particular cyclomethicones, serve as a carrier oil for the active ingredients and thus enable a uniform application to the skin. Due to the high volatility Cyclomethicone evaporates very quickly from the skin, without causing a sticky feeling. By evaporation of the silicone oil, white residues are very quickly visible through the AT agent or the thickener on the skin (whitening effect). Formulas with cyclomethicones are perceived by many consumers to be too dry and not very caring.
  • Cyclomethicone / dodecamethylcyclohexasiloxane (D6).
  • the mixtures can be used on their own or in corresponding preparations as volatile silicone compounds (Cosmet. Toiletries 107, No. 5, 27 [1992]).
  • Silicone oils are often characterized by a lack of degradability.
  • Silicone oil-containing formulations show the disadvantage of the whiteness of antiperspirants, especially black cotton clothing. Silicone oil-free formulations with the same concentration of the antiperspirant active ingredient in the form of a powder show a significantly lower white content.
  • Silicone oils in cosmetics provide the consumer with a low care feeling.
  • Silicone oils also have significant weaknesses in terms of their compatibility with
  • Silicone oils in particular impurities with a polar character hardly to solve. Furthermore, silicone oils are virtually unable to support the penetration of cosmetic ingredients into the skin.
  • the silicone-containing oils also include the high molecular weight known as silicone gums
  • Silicone gums are described for example in US 4152416.
  • High molecular weight means a molecular weight of about 100,000 to 2,000,000 g / mol.
  • Known silicone gums are polymeric polydimethylsiloxanes (INCI name:
  • Dimethicone e.g. B. under the name DC 141 1 fluid and DC 1413 fluid
  • silicone gums for cosmetic applications are, for example, SF1236,
  • Dow Corning's Dow Corning® 1501 Fluid (cyclopentasiloxane, dimethiconol), Dow Corning® 1503 fluid (dimethicone, dimethiconol), Dow Corning® CB 1556 fluid (phenyl trimethicone,
  • silicone fluids and volatile silicone oils such as cyclomethicone, and silicone gums are also known in cosmetic preparations.
  • the dimethicone contained in the commercial product DC 1503 to 88% has a molecular weight below 100,000 g / mol and thus is not a silicone gum according to the invention.
  • WO 9804236 A1 describes antiperspirants (AT) with silicone latex and further thickeners, such as, for example, silicone gum.
  • EP 452762 A2 describes AT aerosols comprising silicone gum and silica, solvent, AT salt and a propellant, wherein a combination of silica and silicone gum as
  • Suspension aid is used.
  • WO 2005074877 A1 describes aerosol antiperspirants with silicones which are inert to the AT agents.
  • WO 2005063188 A1 describes silicone-free AT sprays.
  • DE 102005047370 A1 discloses AT-containing W / O emulsions (sprays) in which the AT agent is dissolved in the inner phase.
  • US 4152416 A teaches AT aerosols with low fog and dust formation with AT salt, propellant, suspending aid and a synthetic polymer rubber (500,000 to 100 million cSt).
  • EP 343843 B1 describes AT aerosols with a spray rate of not more than 0.5 g / s with AT salt, propellant and a combination of silicone polymer and a volatile
  • EP 1803660 A1 discloses a cosmetic product comprising a water-in-oil emulsion with at least one cosmetic or dermatological active substance, at least one
  • Propellant and an aerosol dispenser comprises, wherein the emulsion-contacting parts of the valve of the dispenser of non-metallic
  • WO 2010/054921 A1 discloses an aerosol formulation with a silicone gum.
  • the disadvantage here is an increase in the price of the product.
  • a higher proportion of drug solution in the filling ratio has a negative impact on the skin feel, as a result A wet and cold feeling can be produced on the skin, which in many
  • the product can form large drops, which then trickle down the skin, so that an even distribution of the product on the skin is no longer guaranteed.
  • the droplet size can be influenced. Decreasing the diameter of the housing side bore becomes less
  • the spray rate is the average of the discharge amount of the first 3 sprays of 10 seconds of at least one full (unused, not sprayed) can.
  • the discharge rate describes the amount of discharged gas / active substance mixture and is determined by weighing the can. The determination is carried out at room temperature.
  • silicone gums in particular dimethiconol or dimethicone, contributes to the reduction of the fine fraction in anhydrous aerosol sprays and thus contributes to product safety and safety
  • the invention therefore includes the use of silicone gums in anhydrous
  • Aerosol preparations in particular cosmetic preparations, for reducing the fine fraction of particles in the spray of the aerosol preparations. This leads to
  • Satellite particles are particles that are outside of the direct
  • Application jet for example by turbulence form.
  • Particles are the liquid or solid parts of the aerosol spray.
  • the fines of particles may be formed from solid ingredients of the formulations, such as e.g. Antiperspirant active ingredients such as ACH, or suspending aids, but also from liquid ingredients such as carrier and masking oils and liquefied propellant and mixtures of these ingredients.
  • solid ingredients of the formulations such as e.g. Antiperspirant active ingredients such as ACH, or suspending aids, but also from liquid ingredients such as carrier and masking oils and liquefied propellant and mixtures of these ingredients.
  • the invention includes the use of silicone gums to reduce the fines content of particles in the spray of anhydrous aerosol sprays, the proportion of particles smaller than 10 ⁇ is reduced.
  • the proportion of particles whose particle size is less than 10 ⁇ is reduced compared to the same preparations without silicone gums.
  • the proportion of particles having a particle size of less than 10 ⁇ m in the spray is advantageously 25% or less, based on the addition of silicone gums
  • Clarify example preparations That is, according to the invention alone, by the addition of silicone gums, preferably in a proportion of 0.02 to 0.5 wt.%, Particularly preferably in the range of 0.035 to 0.2 wt.%, In particular in the range of 0.04 to 0 , 1 wt.%, Based on the total mass of the preparation (active ingredient silicone gum), the proportion of particles with a particle diameter of less than 10 ⁇ reduced in the spray cone of the AT aerosol.
  • Active content means the content of the active substance directly without solvent or
  • the proportion by weight refers to the total mass of the preparation, ie
  • Aerosol preparation in the range of 5 to 12 g / 10 s, preferably 6.5 to 10 g / 10 s.
  • Silicone oils that when using silicone gums according to the invention
  • Silicone Gums can be used as demisting agents in sprays to the
  • That silicone gums are also able to reduce the proportion of particles with a
  • Figure 2 shows very clearly the advantageous use of silicone gum to reduce the fine fraction in the spray of aerosol preparations. Reduction of the fine fraction means, in particular, the reduction of the number (volume frequency) of particles having a particle size of less than 10 ⁇ m in the spray material compared to the number of particles in the spray of the same
  • the proportion of active content of silicone gum is according to the invention in the range of 0.02-0.5 wt.%, Based on the total mass of the preparation, particularly preferably in the range of 0.035% to 0.2 wt.%, In particular in the range of 0, 04 to 0, 1 wt.%, Based on the total mass of the preparation including propellant.
  • silicone gums are high molecular weight polydiorganosiloxanes
  • High molecular weight means a molecular weight of about 100,000 to 2,000,000 g / mol.
  • DC 1501 fluid (INCI: cyclopentasiloxane (and) dimethiconol) 15% dimethiconol (active content), 85% cyclopentasiloxane
  • DC 141 1 fluid (INCI: cyclopentasiloxane (and) dimethicone) 15% dimethicone (active content), 85% cyclopentasiloxane.
  • the silicone gums are used in cosmetics mainly because of their property to impart a soft, silky feel on the skin, which also further improves the preparations according to the invention.
  • Density of the particle 1, 00 (gm / cc)
  • the measured value given in the figures is the volume frequency of the particles in%, which have a size less than 10 ⁇ . It is preferably an average of three measured aerosol cans formed, which were measured in each case three times and thus results from a total of nine measurements.
  • the additional gas peak (beam steering) generated by the evaporating propellant gas and thus the constantly changing refractive index is not taken into account in the evaluation of the data.
  • the particle size is according to DIN 66160: 1992-09 paragraph 2.2.5 "a fineness feature of the dimension length.” This means first the particle diameter, which
  • the mean particle size is an average particle size (Römpp Online 3.10).
  • aerosol preparations with a particulate active substance content such as, for example, anhydrous antiperspirant preparations, can be improved in their spray properties with the aid of the silicone gum. That is, in the case of active ingredient solutions in the form of a suspension, the use of silicone gums for reducing the proportion of particles having a particle size of less than 10 ⁇ m in the aerosol spray is particularly advantageous.
  • Wrkstoffe leads to the places where the active ingredients should also be applied. Nebulization of the environment is avoided. In addition, the fine fraction of particles in the spray of the aerosol sprays is reduced, i. the number of particles with one
  • the active ingredients are their solid parts (in suspension) to be understood as particles.
  • Further particulate components of the preparation may be suspending aids or other powdery additives.
  • Suspension aids increase the stability of particles in suspensions.
  • anhydrous antiperspirant formulations are preferably modified phyllosilicates,
  • Clay minerals and / or silicas used as suspending aids used as suspending aids. modified
  • Phyllosilicates in the context of the present invention are phyllosilicates, in particular the abovementioned phyllosilicate types whose organophilicity (also: lipophilicity) - eg. B. by reaction with quaternary ammonium compounds - was increased.
  • organophilicity also: lipophilicity
  • quaternary ammonium compounds - was increased.
  • Phyllosilicates are also referred to as organophilic phyllosilicates. Particularly preferred are stearalkonium hectorite, a reaction product of hectorite and stearalkonium chloride (benzyldimethylstearylammonium chloride), and quaternium-18 hectorite, a reaction product of hectorite and quaternium-18. When using clay minerals, a so-called activator can additionally be used.
  • the suspending aids in particular phyllosilicates, in particular disteardimonium hectorites, are preferably present in an amount of up to 1% by weight, in particular 0.3 to 0.6% by weight, based on the total mass of the preparation.
  • Anhydrous means that the proportion of water in the aerosol preparations, apart from possibly with entrained impurities or water of crystallization, is almost 0% by weight.
  • the invention further relates to aerosol preparations comprising one or more silicone gums and one or more lipids selected from the group of isopropyl esters, preferably isopropyl palmitate, alkyl benzoate, preferably C12-15 alkyl benzoate, triglycerides, preferably caprylic / capric triglyceride, dimethicones and / or hydrocarbon mixtures having a predominant chain length > C16.
  • Hydrocarbon mixture having chain lengths greater than or equal to C16 at least 50%, preferably at least 60%. Hydrocarbon mixtures which consist exclusively of constituents with C16 as chain lengths are accordingly not according to the invention. Among them, C14-22 alkanes are also possible.
  • the hydrocarbon mixture Cx is formed from oligomers of butene or butadiene.
  • the proportion of hydrocarbons Cx with a> 1 is at least 0.5% by weight and with a> 4 (that is, KW> C28) is less than 0.5% by weight, based in each case on the total mass of the hydrocarbon mixture.
  • C20, C24, C28 or C30 hydrocarbons are contained.
  • the proportion of C32, C36 etc. is less than 0.5 wt.%.
  • the proportion of constituents in the hydrocarbon mixture Cx with chain lengths equal to C16 is at least 50%, preferably at least 55%. Hydrocarbon mixtures which consist exclusively of constituents with C16 as chain lengths are not preferred according to the invention.
  • silicone gums in the preferred nonvolatile oils isopropyl palmitate, alkyl benzoate, caprylic / capric triglyceride, and / or linear / branched hydrocarbon oils of predominant chain length> C16.
  • hydrocarbons z. As C14-22 alkanes with predominant chain length> C16 or the preferred Cx mixtures Cx also as a cost effective alternative.
  • Lipids are fats, fatty substances and oils.
  • lipids become the cosmetically important, above all, as emollient ingredients and as skin-specific lipids of the horny layer, which are stored between the horny cells. They enable the skin to store moisture. In addition to the nourishing aspect, lipids become the cosmetic
  • Preparations added to ensure better distribution on the skin and to improve the sensory properties of the preparations.
  • Cyclomethicone used as the main component in aerosol sprays.
  • the proportion of cyclomethicones can be significantly reduced or cyclomethicones can be completely replaced.
  • lipids according to the invention have been partially or completely replaced by consumers as well as the comparative product was evaluated with cyclomethicones, as the following studies show.
  • Figure 3 shows the result of an in-use test with 53 subjects who had tested the new development of the anhydrous antiperspirant spray with a hydrocarbon lipid and triglyceride for a week and then one week as reference the comparison product with the silicone oil cyclomethicone. Finally, the subjects were answered in a questionnaire by the subjects (white bars: comparison product with cyclomethicone, dark bars: new development with silicone gum, hydrocarbon lipid and triglyceride).
  • Hydrocarbons in the packaging can thus limit the function of the packaging.
  • an incompatibility of the oils with the plastic parts of the valve and the spray head is conceivable.
  • inventively preferred hydrocarbons with a proportion of at least 50% of hydrocarbons having a chain length greater than or equal to C16, such as C14-22 Alkanes or the HC mixtures Cx now show the advantages of the raw material group of hydrocarbons, such as stability in market formulas after replacement of
  • Cyclomethicones comparable to those of cyclomethicones, while not exhibiting the typical drawback of packaging incompatibility or only after storage for a very long period of time (e.g., 1 year) at a temperature well above + 25 ° C (e.g.
  • the main difference lies in the kinetics with which the hydrocarbon migrates into the packaging.
  • the kinetics are significantly slowed down so that the consumer can store the product for years at + 25 ° C, without it comes to the typical for hydrocarbon packaging deformations.
  • valves / spray heads are examined for changes.
  • the treated valves / spray heads are then tested for their functionality. It has been found that the packaging compatibility of the formulations according to the invention, in particular with C14-22 alkanes, is very good, the kinetics of the migration of the oil into the packaging material are significantly slower than with other hydrocarbons, such as isohexadecanes or isododecanes, and the polypropylene spray head remains firmly seated on the tin.
  • a mixture of hydrocarbons with a proportion of at least 50% of chain lengths greater than or equal to C16 has proved particularly positive.
  • Hydrocarbon blends of predominantly shorter chain proportions e.g., C13-16 isoparaffin
  • hydrocarbon blends containing almost no levels of chain length greater than C16 exhibit inferior packaging agent compatibility, and this particular blend has exceptionally good packaging compatibility.
  • hydrocarbons according to the invention show a very good compatibility, which could be confirmed in several in-use tests with 60 subjects in each case and short-term application of the products of one week as well as in in vitro tests (HET-CAM and RBC).
  • the lipids according to the invention represent a particularly cost-effective alternative. Since these raw material mixtures are free of silicones, they continue to be the basis for a shortage of silicone oils
  • Antiperspirant formulations available. Due to the advantage shown in the exchange of cyclomethicones by lipids according to the invention, it is therefore particularly advantageous to the content of
  • Aerosol preparations also a better settling behavior of the particulate agent in the aerosol with very good packaging compatibility.
  • the particles sediment significantly slower when cyclomethicone (D5) has been replaced by the hydrocarbon mixture.
  • Alkylbenzoate preferably C12-15 alkyl benzoate, triglycerides, preferably caprylic / capric triglyceride, dimethicones and / or hydrocarbon mixtures having a predominant Kettelini greater than or equal to C16, preferably C14-22 alkanes or hydrocarbon mixtures with Cx, in aerosol formulations extremely advantageous.
  • the proportion of one or more of the preferred lipids in the aerosol preparation is advantageously 0.3 to 15.0% by weight, in particular 0.4 to 10.0% by weight, based on the
  • these individual lipids should be selected in the preferred ranges of proportions. Additionally contained lipids are not included.
  • Antiperspirants are antiperspirants that - in contrast to the
  • Deodorants which generally prevent microbial decomposition of already formed sweat - to prevent the secretion of sweat at all.
  • Protein precipitation and coagulation cause and thus cause a constriction or closure of the sweat gland.
  • Novel AT effectors are based, for example, on the principle of anticholinergics, which interrupt the nerve stimuli, which lead to increased secretion of the sweat glands.
  • antiperspirant active substances according to the invention include those substances which have an influence on perspiration secretion.
  • Preparations may in addition to the actual antiperspirant Wrkstoffen (AT-Wrker) also contain substances that inhibit the microbial degradation of sweat, such as. B. butyloctanoic acid.
  • Wrkstoffen AT-Wrker
  • B. butyloctanoic acid butyloctanoic acid
  • butyl octanoic acid shows only a deodorizing effect and no antiperspirant action, since no influence on the sweat secretion can be deduced from the influence on the bacterial skin flora.
  • Antiperspirant active ingredients in the context of the present application are in particular to be selected from the following groups.
  • antiperspirant active ingredients are used in particular astringents, especially aluminum compounds.
  • astringents especially aluminum compounds.
  • the aluminum salts may be present in ground form or else as hollow spheres or as a mixture thereof.
  • the density of these particles is advantageously in the range of 0.7 to 2.0 g / cm 3 .
  • AT active particles are used as hollow particles, this results in a lower spray cone compared to ground particles with the same valve and spray head specification. This supports the use according to the invention and allows a more targeted application. This in turn reduces white residues due to the lower
  • Aerosol preparations according to the invention therefore also comprise one or more silicone gums and particulate active substances, in particular aluminum chlorohydrates, with a
  • Particle density in the range of 0.7 to 2.0 g / cm 3 since they also improve the spray cone formation.
  • silicone gums in combination with particulate active substances having a particle density in the range of 0.7 to 2.0 g / cm 3 in aerosol formulations thus leads to an improvement in the spray cone.
  • antiperspirants and their suspending aids are to be selected as particulate active substances.
  • AT salt suspensions or gels in which aluminum salts present in powder form are dispersed in various oils.
  • an antimicrobial silver citrate complex as described in DE 202008014407, preferably be used as a cosmetically active ingredient in the cosmetic preparations.
  • the antiperspirant active ingredients from the previously described groups are preferably used in the formulations according to the invention in an amount of 0.5 to 10% by weight, preferably 2 to 6% by weight, based on the total mass of the preparation, ie including any propellant gases present ,
  • Active ingredient solution for an aerosol spray (without propellant gas) and a filling ratio of about 15:85 (active substance solution to propellant gas) is a proportion of about 5.25 wt.% AACH im
  • Aluminum chlorohydrates in particular activated aluminum chlorohydrates (AACH), are preferably used as antiperspirants in antiperspirant aerosol preparations.
  • AACH activated aluminum chlorohydrates
  • the impurities should be easy to agitate and during the
  • AT agents from the group of anticholinergics such as, for example, 4 - [(2-cyclopentyl-2-hydroxyphenylacetyl) oxy] -1, 1-dimethylpiperidinium salts, especially 4 - [(2-cyclopentyl-2-hydroxyphenylacetyl) oxy] 1, 1-dimethyl-piperidinium bromide can to a proportion of preferably 0.05 to 1, 0 wt.%, Preferably 0, 1% -0.7%, in particular 0.3% -0.5 wt.%, Based be added to the total mass of the preparation with propellant gas. Of course, it is possible to add further or other antiperspirant active ingredients and / or deodorants as a cosmetically active ingredient.
  • one or more compounds from the group of deodorants in particular perfumes, alcohols, antimicrobial and / or antiperspirant active ingredients are selected as the cosmetically active ingredient.
  • the aerosol preparations according to the invention preferably comprise one or more silicone gums and a.) One or more lipids, in particular those mentioned above
  • Hydrocarbon lipids selected from the group isopropyl esters, alkyl benzoates, dimethicones and / or hydrocarbon mixtures having a predominant Kettelini greater than / equal to C16 and b.
  • Particulate active ingredients in particular aluminum chlorohydrate, having a particle density in the range of 0.7 to 2.0 g / cm 3 , Propane, propene, n-butane, isobutane, isobutene, n-pentane, n-pentene, isopentane, isopentene, methane and ethane are used singly or in combination as propellant in the aerosol according to the invention.
  • hydrophilic propellants such. As carbon dioxide, can be used advantageously in the context of the present invention, when the proportion of hydrophilic gases is selected low and lipophilic propellant gas (eg., Propane / butane) is present in excess.
  • Propane, butane, isobutane or mixtures of these propellant gases are particularly preferred.
  • the gases mentioned can be used individually or in any desired mixtures with one another. Preference is given to using mixtures having pressure stages of from 1.0 to 3.5 bar. Preferably from 2.5 to 3.0, most preferably a pressure of 2.7 bar.
  • Preferred filling ratios of active substance solution to propellant gas are 40:60 to 5:95, preferably 25:75 to 10:90, very particularly preferably 15:85.
  • the aerosol preparations may contain cosmetic adjuvants and other active ingredients such as are commonly used in deodorant or antiperspirant preparations, such as.
  • cosmetic adjuvants such as are commonly used in deodorant or antiperspirant preparations, such as.
  • Preferred application form for the formulations according to the invention are anhydrous aerosols which come in aluminum cans on the market. This is preferred
  • the particle size distribution was measured for all examples with the same valve and spray head.

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Cosmetics (AREA)

Abstract

L'invention concerne des préparations d'aérosol et leurs cônes de pulvérisation qui sont améliorés par l'ajout de gomme de silicone, du fait que la fraction fine en particules dans le brouillard de pulvérisation est réduite et que dans le même temps la technologie de capteurs et les effets de blanchiment des préparations sont améliorés. En plus de la gomme de silicone sont ajoutés de manière avantageuse à la préparation d'aérosol un ou plusieurs lipides, choisis dans le groupe des esters isopropyliques, des benzoates d'alkyle, des triglycérides et/ou des mélanges d'hydrocarbures ayant une longueur de chaîne prédominante supérieure ou égale à C16 et/ou des substances actives particulaires ayant une densité de particules allant de 0,7 à 2,0 g/cm3.
EP11805836.1A 2010-12-21 2011-12-21 Préparations d'aérosol présentant des propriétés de pulvérisation améliorées Ceased EP2696938A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102010063754A DE102010063754A1 (de) 2010-12-21 2010-12-21 Aerosolzubereitungen mit verbesserten Sprüheigenschaften
PCT/EP2011/073548 WO2012085055A2 (fr) 2010-12-21 2011-12-21 Préparations d'aérosol présentant des propriétés de pulvérisation améliorées

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EP11804680.4A Not-in-force EP2694162B1 (fr) 2010-12-21 2011-12-21 Préparations en aérosol comportant des gommes silicones et des mélanges hydrocarbures spécifiques

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BR (2) BR112013015356A2 (fr)
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WO (2) WO2012085074A2 (fr)

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MX360992B (es) 2012-09-14 2018-11-23 Procter & Gamble Composiciones antitranspirantes en aerosol, productos y metodos.
US10787283B2 (en) * 2013-07-16 2020-09-29 The Procter & Gamble Company Antiperspirant spray devices and compositions
US10766646B2 (en) * 2013-07-16 2020-09-08 The Procter & Gamble Company Antiperspirant spray devices and compositions
US11186424B2 (en) 2013-07-16 2021-11-30 The Procter & Gamble Company Antiperspirant spray devices and compositions
US20150023886A1 (en) 2013-07-16 2015-01-22 The Procter & Gamble Company Antiperspirant Spray Devices and Compositions
US9579265B2 (en) 2014-03-13 2017-02-28 The Procter & Gamble Company Aerosol antiperspirant compositions, products and methods
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BR112016020941B1 (pt) * 2014-03-13 2020-10-13 The Procter & Gamble Company composições antiperspirantes em aerossol e produto
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BR112013015428B1 (pt) 2018-03-06
WO2012085074A3 (fr) 2014-01-09
EP2694162B1 (fr) 2018-08-15
WO2012085074A2 (fr) 2012-06-28
WO2012085055A3 (fr) 2014-01-16
WO2012085055A2 (fr) 2012-06-28
BR112013015356A2 (pt) 2016-08-02
DE102010063754A1 (de) 2012-06-21
EP2694162A2 (fr) 2014-02-12
PL2694162T3 (pl) 2019-02-28
BR112013015428A2 (pt) 2016-08-02

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