EP2665816A1 - Biologisch wirksame nukleotid-moleküle zur gezielten abtötung von zellen, verwendung derselben sowie applikationskit - Google Patents
Biologisch wirksame nukleotid-moleküle zur gezielten abtötung von zellen, verwendung derselben sowie applikationskitInfo
- Publication number
- EP2665816A1 EP2665816A1 EP12704718.1A EP12704718A EP2665816A1 EP 2665816 A1 EP2665816 A1 EP 2665816A1 EP 12704718 A EP12704718 A EP 12704718A EP 2665816 A1 EP2665816 A1 EP 2665816A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- biologically active
- cells
- cell
- nucleotide molecules
- mrna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- Communicable Diseases (AREA)
- Oncology (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102011009470A DE102011009470A1 (de) | 2011-01-21 | 2011-01-21 | Biologisch wirksame Nukleotid-Moleküle zur gezielten Abtötung von Zellen, Verwendung derselben sowie Applikationskit |
| PCT/EP2012/050879 WO2012098234A1 (de) | 2011-01-21 | 2012-01-20 | Biologisch wirksame nukleotid-moleküle zur gezielten abtötung von zellen, verwendung derselben sowie applikationskit |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EP2665816A1 true EP2665816A1 (de) | 2013-11-27 |
Family
ID=45688436
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP12704718.1A Withdrawn EP2665816A1 (de) | 2011-01-21 | 2012-01-20 | Biologisch wirksame nukleotid-moleküle zur gezielten abtötung von zellen, verwendung derselben sowie applikationskit |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20170233760A1 (ja) |
| EP (1) | EP2665816A1 (ja) |
| JP (1) | JP2014511173A (ja) |
| CN (1) | CN103597075A (ja) |
| DE (1) | DE102011009470A1 (ja) |
| WO (1) | WO2012098234A1 (ja) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102013003869B4 (de) | 2013-02-27 | 2016-11-24 | Friedrich-Schiller-Universität Jena | Verfahren zur gezielten Abtötung von Zellen durch zur mRNA-Anbindung ausgerichtete Nukleotid-Moleküle sowie Nukleotid-Moleküle und Applikationskit für solche Verwendung |
| EP3827020A1 (en) | 2018-07-24 | 2021-06-02 | Amgen Inc. | Combination of lilrb1/2 pathway inhibitors and pd-1 pathway inhibitors |
| DE102019000490A1 (de) | 2019-01-23 | 2020-07-23 | HAEMES Verwaltungsgesellschaft mbH | Verwendung von Oligonukleotiden für die Behandlung von Tumoren |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US5898031A (en) | 1996-06-06 | 1999-04-27 | Isis Pharmaceuticals, Inc. | Oligoribonucleotides for cleaving RNA |
| JP4095895B2 (ja) | 2000-12-01 | 2008-06-04 | マックス−プランク−ゲゼルシャフト ツール フォーデルング デル ヴィッセンシャフテン エー．ヴェー． | Ｒｎａ干渉を媒介する短鎖ｒｎａ分子 |
| US7790867B2 (en) * | 2002-12-05 | 2010-09-07 | Rosetta Genomics Inc. | Vaccinia virus-related nucleic acids and microRNA |
| JP2006525811A (ja) * | 2003-05-16 | 2006-11-16 | ロゼッタ インファーマティクス エルエルシー | Ｒｎａ干渉の方法と組成物 |
| AU2005212433B2 (en) * | 2003-05-23 | 2010-12-16 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of gene expression using multifunctional short interfering nucleic acid (multifunctional sINA) |
| US7404969B2 (en) * | 2005-02-14 | 2008-07-29 | Sirna Therapeutics, Inc. | Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules |
| KR100793505B1 (ko) * | 2006-05-30 | 2008-01-14 | 울산대학교 산학협력단 | 복수의 표적 ｍＲＮＡ에 적용 가능한 ｓｉＲＮＡ염기서열을 추출하는 방법 |
| WO2008094516A2 (en) * | 2007-01-29 | 2008-08-07 | City Of Hope | Multi-targeting short interfering rnas |
| DE102007008596B4 (de) | 2007-02-15 | 2010-09-02 | Friedrich-Schiller-Universität Jena | Biologisch wirksame Moleküle auf Grundlage von PNA und siRNA, Verfahren zu deren zellspezifischen Aktivierung sowie Applikationskit zur Verabreichung |
| WO2009020344A2 (en) * | 2007-08-06 | 2009-02-12 | Postech Acad Ind Found | Small interfering rnas (sirnas) controlling multiple target genes and method for preparing the same |
| EP2190994A2 (en) * | 2007-09-17 | 2010-06-02 | Intradigm Corporation | Compositions comprising stat3 sirna and methods of use thereof |
| EP2235180B1 (en) * | 2007-12-28 | 2011-11-09 | Qiagen Sciences, Inc. | Apoptosis inducing positive control for expression modulating experiments |
| DE102009043743B4 (de) * | 2009-03-13 | 2016-10-13 | Friedrich-Schiller-Universität Jena | Zellspezifisch wirksame Moleküle auf Grundlage von siRNA sowie Applikationskits zu deren Herstellung und Verwendung |
| GB2468477A (en) * | 2009-03-02 | 2010-09-15 | Mina Therapeutics Ltd | Double stranded RNA molecule comprising siRNA and miRNA precursors |
-
2011
- 2011-01-21 DE DE102011009470A patent/DE102011009470A1/de not_active Withdrawn
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2012
- 2012-01-20 EP EP12704718.1A patent/EP2665816A1/de not_active Withdrawn
- 2012-01-20 US US13/979,084 patent/US20170233760A1/en not_active Abandoned
- 2012-01-20 WO PCT/EP2012/050879 patent/WO2012098234A1/de active Application Filing
- 2012-01-20 CN CN201280006049.7A patent/CN103597075A/zh active Pending
- 2012-01-20 JP JP2013549831A patent/JP2014511173A/ja active Pending
Non-Patent Citations (1)
| Title |
|---|
| See references of WO2012098234A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103597075A (zh) | 2014-02-19 |
| US20170233760A1 (en) | 2017-08-17 |
| WO2012098234A1 (de) | 2012-07-26 |
| DE102011009470A1 (de) | 2012-08-09 |
| JP2014511173A (ja) | 2014-05-15 |
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