EP2642969A1 - Cosmetic kit and use for improving the appearance of the skin - Google Patents

Abstract

The present invention relates to a cosmetic kit and to the use thereof for improving the appearance of the skin, in particular for preventing and/or controlling cellulite or the orange peel syndrome and/or for slimming down the figure, for increasing the elasticity and firmness of the skin, for stepping up collagen synthesis, for increasing blood microcirculation and for improving thermoregulation of the skin.

Description

 COSMETIC KIT AND USE TO ENHANCE THE APPEARANCE OF THE

 SKIN

The present invention relates to a cosmetic kit and its use to improve the appearance of the skin, in particular to prevent and / or fight against cellulite or orange peel and / or to refine the silhouette, to increase the elasticity skin, to intensify collagen synthesis, to increase blood microcirculation and to improve the thermoregulation of the skin.

Human skin consists of three superimposed tissues: the epidermis, the outermost, the dermis, and the hypodermis, the deepest.

 The natural human epidermis is composed mainly of three types of cells, which are the keratinocytes, a very large majority, melanocytes and Langerhans cells. Each of these cell types contributes by its own functions to the essential role played in the body by the skin.

 The dermis provides the epidermis with a solid support. It is also its nourishing element because it contains a vascularization whose epidermis is free. It consists mainly of fibroblasts and an extracellular matrix itself composed of various extracellular proteins including among others collagen fibers, elastin and various glycoproteins.

 The hypodermis, which is invaginated in the dermis and is attached to the overlying dermis by collagen and elastin fibers, consists essentially of a type of cell specialized in the accumulation and storage of fats, adipocytes. It is the energy reservoir of the body.

 Adipocytes are mature cells resulting from a process of differentiation of fibroblasts into pre-adipocytes and adipocytes; this process is called adipogenesis and / or adipocyte differentiation.

 The roundness and / or overweight are related to the dysfunction of these adipocytes, which contain varying amounts of stored fat in the form of triglycerides. These triglycerides are synthesized in vivo by the adipocytes themselves, according to enzymatic type reactions (lipogenesis), from the free fatty acids contained in the blood in the form of lipoproteins (via a lipoprotein lipase) and glucose brought in particular by the intermediate of certain foods (via an acetyl-CoA carboxylase).

In parallel, the triglycerides thus formed, then stored, in the cells of adipocytes can also degrade (lipolysis), always under the action of enzymes. specific, triglyceride lipases, contained in these same cells, and which are likely to be activated by cyclic AMP, itself regulated by adenylcyclase and capable of being hydrolysed in 5ΆΜΡ by phosphodiesterase.

If, for various reasons (too rich or unbalanced food, sedentary lifestyle, metabolic variation, aging and others), a substantial imbalance settles in the body between lipogenesis and lipolysis, that is to say more precisely if the amounts of fat formed by lipogenesis become appreciably and consistently higher than those which are eliminated by lipolysis, there then occurs in the adipocytes an accumulation of triglycerides which, if it becomes excessive, can be gradually translated by a deformation of the skin caused by the thickening of the hypoderm in which the adipocytes are found.

 Similarly, there is an increase in the subcutaneous adipocyte pool by recruitment of fibroblasts which will begin a process of maturation in pre-adipocyte and adipocyte. The surface of the skin becomes irregular ("cellulite" or "orange peel") and of more or less flaccid or gelatinous consistency, finally giving the silhouette an unsightly general appearance that can evolve between the simple local overload (lipodismorphism), passing by the certain overweight, and finally the real obesity.

However, given the profound physical, aesthetic and sometimes psychological discomfort that it causes to individuals who suffer from it, especially in women, adiposity is nowadays an affection less and less good supported or accepted.

Among the existing solutions to reduce cellulite, and thus improve the aesthetics and well-being of the person, we regularly discover new cosmetic assets.

The active agents to fight against the thickening of the hypodermis, which are molecules of synthetic or natural origin, have biological mechanisms. Indeed, these molecules target mature adipocytes, by intervening on the metabolism of fatty acids which is one of the privileged targets in the control of this adipocyte lipid overload. This metabolism can be modulated:

 either by blocking the transport of glucose inside the adipocyte which leads to a decrease in the fatty acids entering the adipocyte;

 or by inhibition of lipoprotein lipase;

or by activation of triglyceride lipase (or hormone-sensitive lipase), generally by stimulating cyclic AMP, generally by activation of adenylcyclase, or by causing its accumulation by inhibition of phosphodiesterase. Other biological pathways have been explored to influence the mechanism of lipogenesis and / or lipolysis. It has thus been proposed to use antagonists of neuropeptide Y (NPY) receptors, which is a neuromediator involved in a number of physiological processes and whose involvement in the regulation of lipolysis has been demonstrated (P. Valet J. Clin Invest, 1990, 85, 291-295). It is also possible to use α 2 -receptor antagonists or β-adrenergic receptor agonists. Cytosoluble control can also be used, using activators of the production of interleukin 11 (IL11), by cutaneous epidermal cells and / or cells of the sebaceous gland.

All these active ingredients are usually formulated in creams or gels, in which other constituents (other active ingredients or excipients) are present.

The problems related to this type of product are that the results are not significantly observed by the users, who get bored quickly. In addition, topical lotions may leave marks that may stain worn clothing after applying the formulation or leave a sticky skin feeling.

On the other hand, it has been found, as can be seen in particular in WO 2009/077834 that additives having emission and / or absorption properties in the infrared region also interact with the skin. These additives may be shaped into polymeric compositions, in particular based on polyamide, which are then spun to constitute so-called "active" fibers that can be used, for example, to design textile articles making it possible to reduce cellulite. In this case, the operation of these textile articles is physical / thermal, that is to say that there is a thermoregulation on the surface of the skin through which the microcirculation is activated, and which promotes the elimination cellulite.

There are also products combining cosmetic formulas (creams or gels) with fabrics that are either non-active or active with the same operating principle as the cosmetic formula. For example:

 - non-active glue / cream or cosmetic gel: the glue has no isolated action on improving cellulite, it is only an aid to maintaining the cosmetic formulation on the skin;

- aluminum patch / cosmetic cream: the patch helps maintain and accelerates the absorption of the cosmetic active;

- bioceramics / bioceramics-coated bermuda shorts: bioceramic coated bermuda and cosmetic cream containing bioceramics have the same mechanism of action and no additional effects related to the use of both products are observed;

 tissues impregnated with microcapsules of cosmetic active ingredients. In this case, the fabric has a function of supporting the active substance, which is generally released due to the friction tissue / skin. The disadvantages of this technology are:

 - too fast release of additives and disappearance of assets after a few washes;

- Insufficient amount of active applied to observe an effect because microcapsules volume very low compared to the amount applicable by means of a cosmetic cream;

 - active formulation used identical to that of cosmetic creams and lotions.

There is therefore still a need to propose new "anticellulite" solutions that satisfy the users of such cosmetic products. The need lies in an increase in the effectiveness of the elimination of unsightly forms caused by subcutaneous fat deposits.

One of the aims of the present invention is therefore to propose a new product that is more efficient and does not have the disadvantages mentioned above. The invention meets this need by proposing a cosmetic kit to significantly improve the appearance of the skin, including the roughness and the firmness of the skin which are altered due to the presence of cellulite.

More specifically, the invention relates to a cosmetic kit comprising:

 a topical formulation comprising at least one cosmetic active agent and

a textile article constituted at least in part by polymer fibers which have a capacity for transmitting and / or absorbing infrared radiation in the wavelength range situated between 2 μm and 20 μm. The present invention also relates to the cosmetic use of the kit of the invention to improve the appearance of the skin, in particular to prevent and / or fight against cellulite or orange peel and / or to refine the silhouette. In particular, the cosmetic use according to the invention makes it possible to increase the elasticity and firmness of the skin, the intensification of collagen synthesis, the increase in blood microcirculation and the improvement of thermoregulation of the skin. skin. The kit of the invention implements a topical formulation comprising at least one cosmetic active.

The cosmetic active ingredient according to the invention is advantageously an active agent having a cellulite reduction effect. The term "cellulite reduction effect" in the context of the invention means a compound whose activity leads to reducing the thickness of the hypodermis and / or preventing its thickening, in particular by controlling the renewal and / or the number of adipocytes, via inhibition and / or a decrease in the transformation of fibroblasts into pre-adipocytes and adipocytes.

The control of the renewal and / or the number of adipocytes at the level of the hypodermis, thus allows:

 -to reduce the thickness of the hypodermis and / or prevent its thickening;

 -prevent and / or fight against cellulite and / or orange peel, and / or refine or thin the silhouette.

The topical formulation of the invention may be in the form of an aqueous, alcoholic or aqueous-alcoholic solution or suspension or of an oily suspension or of a solution or dispersion of the lotion or serum type, an emulsion of liquid or semi-liquid consistency of the milk type, obtained by dispersion of a fatty phase in an aqueous phase (oil in water) or conversely (water in oil), or a triple (water in oil in water or oil in water) in Oil), or a suspension or emulsion of soft, semi-solid or solid consistency of the cream, gel, microemulsion or ionic and / or nonionic type vesicular dispersions. These formulations are prepared according to the usual methods.

This formulation can be more or less fluid and have the appearance of a white or colored cream, an ointment, a milk, a lotion, a serum, a paste, a mousse . It can optionally be applied to the skin in the form of an aerosol. It can also be in solid form, and for example in the form of a stick. Preferably, the formulation according to the invention will be in the form of a lotion, a serum, a milk, a cream, an oil, a stick, a patch or even a spray or aerosol. When the formulation is an emulsion, the proportion of the fatty phase may range from 2 to 80% by weight, and preferably from 5 to 50% by weight relative to the total weight of the formulation. The oils, the waxes, the emulsifiers and the coemulsifiers used in the formulation in emulsion form are chosen from those conventionally used in the cosmetics field. The emulsifier and the coemulsifier are present, in the formulation, in a proportion ranging from 0.1 to 30% by weight, and preferably from 0.5 to 20% by weight relative to the total weight of the formulation.

The emulsion may further contain lipid vesicles.

 When the formulation is a solution or an oily gel, the fatty phase may represent more than 90% of the total weight of the formulation.

In a known manner, the formulation of the invention may also contain the usual adjuvants in the cosmetic fields, such as hydrophilic or lipophilic gelling agents, hydrophilic or lipophilic active agents, preservatives, antioxidants, solvents, perfumes, fillers, filters, pigments, chelating agents, odor absorbers and dyestuffs.

The amounts of these various adjuvants are those conventionally used in the fields under consideration, and for example from 0.01% to 20% of the total weight of the formulation. These adjuvants, depending on their nature, can be introduced into the fatty phase, into the aqueous phase, into the lipid vesicles and / or into the nanoparticles.

As oils or waxes that can be used in the invention, mention may be made of mineral oils (vaseline oil), vegetable oils (liquid fraction of shea butter, sunflower oil), animal oils (perhydrosqualene), synthetic oils ( Purcellin oil), silicone oils or waxes (cyclomethicone) and fluorinated oils (perfluoropolyethers), bees, carnauba or paraffin waxes. To these oils can be added fatty alcohols and fatty acids (stearic acid). As emulsifiers that may be used in the invention, mention may be made, for example, of glycerol stearate, polysorbate 60 and the PEG-6 / PEG-32 / glycol stearate mixture sold under the name Tefose® 63 by the company Gattefosse.

As solvents that can be used in the invention, mention may be made of lower alcohols, in particular ethanol and isopropanol, and propylene glycol.

As hydrophilic gelling agents that may be used in the invention, mention may be made of carboxyvinyl polymers (carbomer), acrylic copolymers such as acrylate / alkylacrylate copolymers, polyacrylamides, polysaccharides such as hydroxypropylcellulose, natural gums and clays, and, as lipophilic gelling agents, mention may be made of modified clays such as bentones, metal salts of fatty acids such as aluminum stearates and hydrophobic silica, ethylcellulose and polyethylene. Among the cosmetic active agents likely to have a cellulite reduction effect we can find:

 1) phosphodiesterase inhibitors,

 2) vegetable extracts and marine extracts

 3) Peptides or proteins

 4) active agents acting on microcirculation (vasoprotective or vasodilatory)

5) firming and / or anti-glycating agents (preventing the attachment of sugar to the collagen fibers) and / or antioxidants,

 6) anti-lipogenesis agents: interleukin-11 activators.

The phosphodiesterase inhibitors are advantageously chosen from:

 xanthine derivatives such as caffeine and its derivatives, in particular the 1-hydroxyalkylxanthines described in document FR-A-2, 617,401, caffeine citrate, theophylline and its derivatives, theobromine, acefylline, aminophylline, the chloroethylthéophylline, diprofylline, diniprophylline, etamiphylline and its derivatives, etofylline, proxyphylline;

 combinations containing xanthine derivatives, such as the combination of caffeine and silanol (methylsilanetriol caffeine derivative), and for example the product marketed by the company Exsymol under the name caféisilane C;

 compounds of natural origin containing xanthine bases and in particular caffeine, such as extracts of tea, coffee, guarana, mate, cola (Cola Nitida) and in particular the dry extract of guarana fruit ( Paulina sorbilis) containing 8 to 10% caffeine;

 - Ephedrine and its derivatives which can be found naturally in plants such as Ma Huang (Ephedra plant).

As plant extracts and extracts of marine origin, which are either active on the receptors to be inhibited, such as J3-2-blockers, NPY-blockers (described in patent EP 838217), or inhibit the synthesis of LDL or VLDL, which are active to stimulate R-receptors and G-proteins, leading to the activation of adenylcyclase, may be mentioned for example:

 • Vegetable extracts:

 - Garcinia Cambogia,

 extracts of Bupleurum chinensis,

- extracts of climbing ivy (Hedera Helix), arnica (Arnica Montana L), rosemary (Rosmarinus officinalis N), marigold (Calendula officinalis), sage (Salvia officinalis L), ginseng (Panax ginseng), of St. John's Wort (Byperycum Perforatum), frog (Ruscus aculeatus L), common meadow (Filipendula ulmaria L), orthosiphon (Orthosiphon Stamincus Benth), birch (Betula alba), cecropia and argan tree,

 - Ginkgo biloba extracts,

 - horsetail extracts,

 - escin extracts,

 extracts of cangzhu, extracts of chrysanthellum indicum, extracts of dioscorea rich in diosgenin or diosgenin or pure hecogenin and their derivatives,

extracts of plants of the genus Armeniacea, Atractylodis Platicodon, Sinommenum, Pharbitidis, Flemingia,

 extracts of Coleus such as C. Forskohlii, C. blumei, C. esquirolii, C. scutellaroides, C. xanthantus and C. Barbatus, such as Coleus Barbatus root extract containing 60% forskolin,

 -Bellote extracts,

 extracts of Guioa, Davallia, Terminalia, Barringtonia, Trema, Antirobia.

 - the extracts of the camellia sinensis leaf.

• Extract of marine origin: extracts of algae or phytopancton, such as rhodysterol or Laminaria Digitata extract marketed under the name PHYCOX75 by the company Secma, the skeletonema algae described in patent FR 2

782 921 or the diatoms described in patent FR 2774292.

The peptides or proteins are preferably chosen from:

 the peptides derived from parathyroidian hormone as described in patents FR 2 788058 and FR 2781231 of Sederma or the peptides described in document FR 2 786 693, or even any other peptide having lipolytic properties,

 protamines and their derivatives such as those described in document FR-A-2, 758,724. Among the active agents acting on microcirculation (vasoprotectants or vasodilators), mention may be made of flavonoids, ruscogenins, natural or synthetic esculosides (including Permethol marketed by the SOCHIBO company), escin extracted from horse chestnuts, nicotinates, heparin methyl chalcone, holly, lavender or rosemary essential oils, extracts of Ammi visnaga.

Among the firming and / or anti-glycating agents (preventing the attachment of sugar to the collagen fibers) and / or antioxidants, mention may be made of the extracts of Centella asiatica and Siegesbeckia, silicon, amadorine, ergothioneine and its derivatives, plant extracts of the family Ericaceae, including extracts of blueberry (Vaccinium angustifollium), vitamin C and its derivatives.

Preferably, the cosmetic active agent is chosen from phosphodiesterase inhibitors, active agents acting on microcirculation (vasoprotectants or vasodilators), firming and / or anti-glycating agents (preventing the binding of sugar to the collagen fibers) and / or anti-oxidants, anti-lipogenesis agents, and mixtures thereof.

The amount of cosmetic asset can vary to a large extent and depends on the nature of the asset or assets used. In general, the cosmetic active agent (s) are present in a concentration ranging from 0.0001% to 20%, preferably from 0.001% to 10% and even more preferentially from 0.1% to 5% by weight relative to the total weight of the formulation. According to an advantageous embodiment, the topical formulations according to the invention contain at least two cosmetic active agents.

The cosmetic active can be either (i) encapsulated in a coating such as microspheres, nanospheres, oleosomes or nanocapsules, or (ii) compartmentalized in a fatty phase containing the main constituents of sebum.

According to a first embodiment, the formulation may be in a form such that the active agent is encapsulated in the core or the wall of a coating such as microspheres, nanospheres, oleosomes, niosomes or nanocapsules, preferably nanocapsules.

 The encapsulation or absorption of lipophilic active principles in particles of submicron dimensions has been known for several years and is widely used in particular in the cosmetic and dermatological fields. Indeed, these particles called nanoparticles are able to cross the superficial layers of the stratum corneum and / or the follicular ostium and penetrate into the upper layers of the living epidermis to release the active ingredient. This penetration into deeper layers widens the action space of active ingredients and protects them from rapid elimination by simple friction.

The term 'nanoparticles' mainly encompasses two different systems: 'nanospheres' consisting of a polymer matrix in which the active ingredient is absorbed and / or adsorbed and / or mixed, as well as 'nanocapsules' having a core-like structure envelope, that is to say a structure consisting of a liquid lipid core at room temperature formed or containing the active ingredient in solubilized form or pure, which heart is encapsulated in a continuous protective envelope insoluble in the medium.

 The nanocapsules according to the present invention are generally small in order to obtain optimal bioavailability of the active compound. Preferably, the size of these nanocapsules is between 10 nm and 1000 nm and more particularly between 30 nm and 500 nm.

 Different types of nanocapsules can be used according to the present invention. By way of example, mention may be made of the nanocapsules described in patent application EP-0274961, the nanocapsules provided with a lamellar coating described in application EP-0780115, the nanocapsules whose continuous polymeric envelope is insoluble in water. is composed of polyesters as described in applications EP-1025901, FR-2787730 and EP-1034839, or else the biodegradable nanocapsules described in the patent application FR-2,659,554, or non-biodegradable described in the patent application WO-93/05753.

Nanocapsules made of biodegradable polymers penetrate the skin and degrade in the epidermis under the action of the enzymes that are present, whereas the nanocapsules in non-biodegradable polymers only penetrate the superficial layers of the stratum corneum and are eliminated naturally during renewal of the skin.

It will also be possible to use systems carrying the active product specifically in the pilosebaceous unit, such as microspheres of natural or synthetic polymers or fats with a melting point greater than 50 ° C., loaded with at least one active product, and of which at least 80% by weight of these microspheres have a diameter of between 3 μm and 1 μm described in application EP 0 375 520; vehicles consisting of porous particles of size between 10 .mu.m and 100 .mu.m to release, in a controlled manner, the active ingredients described in US Pat. No. 4,690,825.

The kit of the invention implements a textile article constituted at least in part by polymer fibers which have a capacity for transmitting and / or absorbing infrared radiation in the wavelength range between 2 m and 20 m. pm.

The polymer fibers according to the invention preferably have a number of infrared radiation absorption peaks greater than 10 in the following ten frequency ranges: 3.00 +/- 0.30μηι, 6.20 +/- 0, 50μιη, 8.00 +/- 0.25μηι, 8.50 +/- 0.25μηι, 9.00 +/- 0.25m, 9.50 +/- 0.25μπι, 10.00 +/- 0 , 25μηι, 10.50 +/- 0.25μπι, 11.00 +/- 0.25μπι, 14.60 +/- 2.10μπι, at least one peak being present in at least 7 of these ten frequency ranges. The infrared radiation absorption spectrum may be determined by any method known to those skilled in the art. One possible method is the use of a Bruker Equinox 55 device, with a resolution of 4 cm ^-1, in which case the spectrum obtained is in ATR ("Atenuated Total Reflectance") form, using a ZnSe crystal.

The polymer may be selected from the group consisting of polyesters, polyolefins, cellulose-ester-based polymers such as cellulose acetate, cellulose propionate, rayon, viscose and polymers of the same family. acrylic polymers and copolymers, polyamides, polyhexamethylene adipamide (PA66) or polycaproamide (PA6), or copolymers thereof in all proportions, or mixtures of any of the polymers mentioned above.

 According to a preferred embodiment, the polymer which composes the fiber is based on polyamide, chosen between polyamide 6, polyamide 66 and copolymers of polyamide 6 / polyamide 66 in all proportions.

The polymer fibers according to the invention comprise in the polymer matrix, mineral fillers having absorption and / or emission properties in the far-infrared region 2-20 μm.

 The mineral fillers are chosen from oxides, sulphates, carbonates, phosphates and silicates.

 Preferably, the oxide is selected from titanium dioxide, silicon dioxide and magnesium oxide.

 The sulphate may be selected from alkali metal sulphates, preferably from barium sulphate, calcium sulphate and strontium sulphate.

The carbonate is advantageously chosen from calcium carbonate or sodium carbonate. Preferably, the silicate is chosen from aluminosilicates, preferably from actinolite, tourmaline, serpentine and kaolin.

 The phosphate may be chosen from zirconium phosphates, apatite or their mixtures.

According to an advantageous embodiment of the invention, the mineral fillers are of at least one type chosen from oxides, sulphates, carbonates, phosphates and silicates. Preferably, the mineral fillers are of two types chosen from the following types: oxides, sulphates, carbonates, phosphates and silicates. Even more advantageously, the mineral fillers are of three types chosen from among the following types: oxides, sulphates, and silicates.

In a particularly advantageous manner, the fiber comprises three mineral fillers. Preferably, at least two mineral fillers selected from titanium dioxide, an alkali metal sulfate and an aluminosilicate. Preferably, at least two mineral fillers selected from titanium dioxide, barium sulfate, and tourmaline are present in the fiber.

The combination of the three mineral fillers is preferably the combination of titanium dioxide / alkali metal sulphate / alumino-silicate; preferably titanium dioxide / barium sulfate / tourmaline.

In this case, the proportion by weight of the three mineral fillers is between 80:10:10 and 10:30:60, and more specifically in proportions of 50:25:25.

According to one embodiment of the invention, the proportion by weight of the combination of mineral fillers relative to the total weight of the polymeric composition is greater than 1.0%, preferably greater than or equal to 1.5% or more. preferably still greater than or equal to 2.5%.

 Preferably, the proportion by weight of the combination of inorganic fillers relative to the total weight of the polymeric composition is less than 9%, preferably less than 6%, advantageously less than 4.5%. The mineral fillers according to the invention advantageously have an average particle size of less than 2 m.

 The mineral fillers of the polymeric composition advantageously have a particle size of less than 1.0 μm, preferably a particle size of less than 0.5 μηη. The mineral fillers are incorporated during the synthesis phase of the polymer, or by direct mixing with the polymer during the spinning phase of the filaments, or by means of a concentrate of particles in the form of a masterbatch. ), which can be subsequently diluted to predetermined concentrations in the polymeric mass during the spinning phase.

The process for obtaining such fibers according to the invention may consist in producing a suspension of the mineral fillers such as, for example, an aluminosilicate, titanium dioxide and an alkali metal sulphate stabilized with surfactants. The suspension is then added to the synthesis of the polyamide. An alternative is to introduce a part of the mineral fillers, previously put in the form of a masterbatch in the molten polymer at the time of spinning. The polyamide obtained is cooled, cut and remelted before passing through an extruder to form the fiber. The polyamide fibers according to the invention contain the mineral fillers uniformly dispersed in the polymer matrix.

In the case of fibers obtained by melt spinning, the mineral fillers can be introduced into the molten polymer by means of a mixing device, for example upstream of a spinning device. By spinning the additive polymer composition continuous multifilament yarns, monofilaments, short and long fibers, or mixtures thereof can be obtained. The term "fiber" is the set of yarns, fibers and filaments that can be obtained by spinning. The fibers obtained from the polymeric compositions presented in the present invention can be subjected to all the textile treatments known to those skilled in the art, such as extrusion, stretching, texturing, dyeing, finishing etc.

According to a particularly preferred embodiment of the invention, at least a portion of the polymer fibers used in the textile article are fibers marketed under the names "infra-red emitter son" or "FIR emitter yarns" or EMANA ® by RHODIA. These are polyamide 66 fibers comprising three mineral fillers: titanium dioxide, an acali metal sulfate, and an alumino-silicate. The textile articles can be obtained from a single type of fiber, or from a mixture of fibers of different types.

 By textile articles is meant in particular fabrics, knits and nonwovens.

 The textile articles are made by known techniques using polyamide fibers as raw material.

The interaction between the textile article and the skin creates a thermoregulation and promotes blood microcirculation.

 Such stimulation results in a decrease in cellulite. In addition, there is an improvement in muscle recovery and elasticity of the skin.

According to a particularly advantageous embodiment, the textile article is in the form of a garment, preferably a Bermuda shorts, a tights, pants or any other textile article in direct contact with the skin. The use of a textile article as defined above, in combination with the topical formulation comprising a cosmetic active agent allows better absorption and transport of the active ingredients of the topical formulation, also resulting in better elimination of the compounds targeted by the cosmetic actives. The invention therefore also relates to the cosmetic use of the cosmetic kit as defined above to improve the appearance of the skin, in particular to prevent and / or fight against cellulite or orange peel and / or to refine the skin. silhouette, especially by increasing the elasticity and firmness of the skin.

 More specifically, the topical formulation and the textile article are used successively. In particular, the use of the cosmetic kit comprises the topical application to the skin of the topical formulation comprising at least one cosmetic active agent followed by the application, on the area of the skin where the topical formulation has been applied, of the textile article constituted at least in part by polymer fibers which have a capacity of emission and / or absorption of infrared radiation in the wavelength range between 2 μπι and 20 μητι.

 Preferably, the application of the textile article having a capacity for emitting and / or absorbing infrared radiation in the wavelength range between 2 μιτι and 20 μηη consists in wearing the textile article, in particular under the shape of a garment, for example a bermuda, a tights or pants.

The kit according to the invention can be used locally on the areas of the body marked by a thickening of the hypodermis.

In particular, the topical formulation comprising at least one cosmetic active on the areas of the body to be refined, in particular on the hips, buttocks, thighs, abdomen and abdominal belt, will be applied. Then, a garment made at least partly from polymer fibers which have a capacity of emission and / or absorption of infrared radiation in the wavelength range between 2 μηη and 20 μητι.

 The wearing of the recommended garment is preferably a minimum of 6 hours per day. Preferably, the application of the topical formulation followed by the wearing of the textile article will be carried out daily, for example once or twice a day, for a duration of treatment of several weeks, generally from 10 days to 8 weeks, preferably from 2 to 8 weeks.

 For better effectiveness, the wearing of the garment should be made a few minutes after the application of the topical formulation, as soon as the skin has a dry touch.

One of the great advantages of the present invention resides in the possibility of being able, whenever necessary or desirable, to carry out "soft" treatments which are very localized and selective thanks to the mode of application by the topical route.

The treatment can be renewed periodically, depending on the thickness and / or thickening of the hypodermis and / or cellulite and / or orange peel. the individual to treat. The cosmetic use according to the invention also makes it possible to increase the elasticity and firmness of the skin, the intensification of collagen synthesis, the increase in blood microcirculation and the improvement of thermoregulation of the skin. .

Surprisingly, the combination of the topical formulation and the textile article makes it possible to obtain greater efficiency in the reduction of cellulite.

The present invention further has the following advantages:

 - High resistance to washing / cleaning of the mineral fillers of the textile article by incorporating these fillers into the polymeric matrix,

 the transmitting / absorbing article of infrared radiation amplifies the effect of the topical formula, in particular by thermoregulation of the skin and thus improves the absorption of the cosmetic active ingredients,

 the transmitting / absorbing infrared radiation textile article promotes the transport and permeability of the topical formulation by increasing the blood microcirculation of the treated area;

 - The combination of these two completely different and complementary mechanisms of operation allows a significant improvement of the apect of the skin. DESCRIPTION OF THE FIGURE

 FIG. 1 represents a diagram of a graph of the measurement of mechanical deformation of the skin as a function of time according to the cutometry method.

 FIG. 1 shows the measurement of this deformation (S) during aspiration, which leads to the determination of the following parameters:

 - Maximum extensibility: Uf (final deformation);

 - Immediate extensibility: Ue (Elasticity);

 - Viscoelastic extensibility: Uy (Plasticity);

 - Immediate elastic recovery: Ur;

 - Elastic deformation ratio (firmness F): Ur / Ue

 - Elastic recovery rate: Ur / Uf

 - Viscosity elasticity rate: Uy / Ue.

 This figure is explained in more detail in the following examples.

Examples of embodiments of the invention are given below. These examples are given for illustrative purposes and without limitation. EXAMPLES Tests Six topical formulation + textile article tests were carried out to demonstrate the synergistic effect associated with the combined use of these two elements in the treatment of cellulite. a) Bermuda shorts EMANA® infra-red + topical formulation A

b) Bermuda shorts EMANA® infra-red + topical formulation B

c) EMANA® infra-red emitting yarn shorts + Topical formulation C

d) EMANA® infra-red emitting yarn shorts + Topical formulation D

e) EMANA® infra-red shorts Bermuda shorts + Topical formulation E

f) EMANA® Infra-Red Imaging Shorts + Topical Formulation F

g) EMANA® Infra-Red Imaging Shorts Bermuda + Topical Formulation G

h) EMANA® infra-red emitting wire fabric + H topical formulation with:

 Topical formulation A; gel comprising 1.5% by weight of caffeine, 0.3% by weight of salicylic acid and 0.3% by weight of retinol.

Topical formulation B: emulsion comprising 2.0% by weight of caffeine, 0.3% by weight of Ginko-Biloba and 0.3% by weight of retinol. Topical formulation C: emulsion 1.5% by weight of caffeine, 0.3% by weight of salicylic acid and 0.3% by weight of thorny hedge (Ruscus aculeatus).

Topical formulation D (commercial formulation ROC - RETINOL® Anti-Cellulite): retinol, caffeine, forskolin; TetraHydroxylPropyl Ethylenediamine (THPE) and Carnitine.

Topical formulation (commercial formulation BIOTHERM® - Celluli Laser®): complex of fibrins, plankton, caffeine, ginseng, Ginkgo Biloba, kola nuts.

Topical formulation F (commercial formulation VICHY® - Lipocure Serum®): water, alcohol, cyclohexasiloxane, propylene glycol, glycerine, caffeine, dimethicone phosphate peg-7, triethanolamine, caprylic / capric peg-6, lycerides, carbomer, manganese gluconate , salicylic acid, escin, ginkgo biloba, rutinyl disodium disulfate, dioscorea opposita, xanthan gum, acrylate / C10-30 alkyl acrylate crosspolymer. Topical Formulation F (L'Oreal® Commercial Formulation - Perfect Slim Lifting Pro®): water, alcohol, propylene glycol, glycerine, caffeine, dimethicone salicylic acid, silica, mint extract, ginkgo-biloba, extract of Ruscus aculeatus, perfume, extract of "wild Yan", limonene, linalool.

Topical formulation H (Procter & Gamble® commercial formulation - PLAY®): water, glycerin, niacinamide, isohexadecane, dimethicone, isopropyl isostearate, polyacrylamide, sorbitan estearate, cetyl ethanol, sucrose polycottonseedate, tocopheryl acetate, C13-14 isoparaffin , panthenol, benzyl alcohol, titanium dioxide, stearyl ethanol, dimethiconol, ethylparaben, PEG-100 stearate, perfume, laureth-7, propylparaben, stearic acid, disodium EDTA, sodium ascorbyl phosphate, bht, zinc oxide, citric acid, extract of camellia sinensis leaf, methylparaben, c 19140, ammonium polyacrylate, c 16035.

Results

 Roughness of the skin:

The reduction in skin roughness was measured using a standardized method of analyzing the skin surface with a 3D Nikon D70S 3D photographic camera. Captured images are analyzed by specialized software (Scion for Windows Software) which translates the relief into roughness. Roughness is the measure of the average variation (standard deviation) of the peaks and valleys of the image. Standard treatments against cellulite based on topical formulations (topical formulations A to G) alone or using only a textile article emitting / absorbing in the wavelength range 2-20 μιη, show a reduction in the roughness of the skin from 8 to 12%. The results obtained with the use of Bermuda combination EMANA® infra-red emitting son + anti-cellulite formulation (topical formulations A to G) for 30 days (6 hours per day) have demonstrated an additional reduction of less than 2% of the roughness of the skin compared to the isolated effect of each of the standard methods. Firmness of the skin:

The increase in skin firmness was also measured with a standardized method which consists of analyzing cutometry: that is to say of the measurement of the mechanical deformation curve of the skin according to FIG. The principle of this technique is to create on the surface of the skin a depression and to measure the induced vertical displacement of the skin. This technique is based on a suction method. A depression is created in the probe in order to suck the skin. The cutometer measures the vertical displacement of the surface of the skin as a function of time and the depression exerted in the probe. We can thus determine the rigidity of the skin and its ability to recover its initial state.

 The measurement of this deformation (S) during aspiration leads to the determination of the following parameters (see FIG. 1):

 - Maximum extensibility: Uf (final deformation);

 - Immediate extensibility: Ue (Elasticity);

 - Viscoelastic extensibility: Uy (Plasticity);

 - Immediate elastic recovery: Ur;

 - Elastic deformation ratio (firmness F): Ur / Ue

 - Elastic recovery rate: Ur / Uf

 - Viscosity elasticity rate: Uy / Ue

The value "F" was measured at time zero ("F ₀ ") and after 30 days ("F ₃₀ ") using tissue h) for 8 hours.

F (%) = (F ₃₀ -Fo) / Fo

 The results obtained are reported in Table 1 below.

 Table 1

The results obtained with the use of the combination of tissue infrared emitting son + cosmetic formulation H for 30 days (8 hours per day) demonstrated a synergistic effect with an additional increase of 6.8% of the firmness of the skin (F%) relative to the best isolated effect of each product (ie to the formulation alone) or a gain of + 2.5% over the sum of the increases obtained by the isolated products (9 , 70 + 4.30 = 14% while the combination reaches 16.5%). conclusions

Clinical studies show that there is a synergistic effect related to the use of the composition of the invention which comprises both the topical formulation comprising at least one cosmetic active and the Rhodia technology of infra-red emitting son, for the treatment of the appearance of orange peel and reduction of the appearance of celulite.

Claims

Cosmetic kit comprising:

a topical formulation comprising at least one cosmetic active and,

a textile article constituted at least in part by polymer fibers which have a capacity for transmitting and / or absorbing infrared radiation in the wavelength range between 2 μm and 20 μm.

Cosmetic kit according to Claim 1, in which the topical formulation is in the form of an aqueous, alcoholic or aqueous-alcoholic solution or suspension or of an oily suspension or of a solution or dispersion of the lotion or serum type, of a liquid or semi-liquid consistency emulsion of the milk type, obtained by dispersion of a fatty phase in an aqueous phase: oil in water or conversely: water in oil, or a triple: water in oil in water or oil in Water in oil, or a suspension or emulsion of soft, semi-solid or solid consistency of the cream, gel, microemulsion or ionic and / or nonionic type vesicular dispersions.

Kit according to claim 1 or 2, wherein the cosmetic active is an active having a cellulite reduction effect.

Kit according to any one of Claims 1 to 3, in which the cosmetic active agent is chosen from:

 1) phosphodiesterase inhibitors,

 2) vegetable extracts and extracts of marine origin,

 3) peptides or proteins,

 4) active agents acting on the microcirculation,

 5) the firming and / or anti-glycating and / or antioxidant active ingredients,

 6) anti-lipogenesis agents: interleukin-11 activators.

Kit according to any one of claims 1 to 4, wherein the polymer which composes the fibers is chosen from the group comprising polyesters, polyolefins, cellulose-ester-based polymers, acrylic polymers and copolymers, polyamides, their copolymers or mixtures.

Kit according to any one of claims 1 to 5, wherein the polymer which composes the fibers is based on polyamide, chosen between polyamide 6, polyamide 66 and copolymers of polyamide 6 / polyamide 66 in all proportions.

7. Kit according to one of claims 1 to 6, wherein the polymer fibers comprise in the polymer matrix, mineral fillers having absorption and / or emission properties in the far infrared region 2-20. μηι.

Kit according to claim 7, wherein the mineral fillers are uniformly dispersed in the polymeric matrix.

Kit according to claim 7 or 8, in which the mineral fillers are chosen from oxides, sulphates, carbonates, phosphates and silicates.

10. Kit according to any one of claims 7 to 9, wherein the mineral fillers are of three types selected from the following types: oxides, sulfates, and silicates.

11. Kit according to one of claims 7 to 10, wherein the three mineral fillers are the combination of titanium dioxide / alkali metal sulfate / alumino-silicate.

12. Cosmetic use of the kit as defined in one of claims 1 to 11 to improve the appearance of the skin.

13. Use according to claim 12, wherein the topical formulation and the textile article are used successively.

14. Use according to claim 13, comprising the topical application to the skin of the topical formulation comprising at least one cosmetic active agent followed by the application, on the area of the skin where the topical formulation has been applied, of the article. textile formed at least in part by polymer fibers which have a capacity of emission and / or absorption of infrared radiation in the wavelength range between 2 pm and 20 μηη.

15. Use according to claim 14, wherein the application of the textile article having a capacity of emission and / or absorption of infrared radiation in the wavelength range between 2 μηι and 20 μηι, is to wear the textile article in the form of a garment.