EP2567220A1 - Procédé et dispositif de contrôle d'objets pour applications pharmaceutiques - Google Patents

Procédé et dispositif de contrôle d'objets pour applications pharmaceutiques

Info

Publication number
EP2567220A1
EP2567220A1 EP11709090A EP11709090A EP2567220A1 EP 2567220 A1 EP2567220 A1 EP 2567220A1 EP 11709090 A EP11709090 A EP 11709090A EP 11709090 A EP11709090 A EP 11709090A EP 2567220 A1 EP2567220 A1 EP 2567220A1
Authority
EP
European Patent Office
Prior art keywords
objects
transport
arrangement according
transport trough
trough
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP11709090A
Other languages
German (de)
English (en)
Inventor
Reinhold Schmieg
Achim Brockhoff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Robert Bosch GmbH
Original Assignee
Robert Bosch GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robert Bosch GmbH filed Critical Robert Bosch GmbH
Publication of EP2567220A1 publication Critical patent/EP2567220A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • G01N21/88Investigating the presence of flaws or contamination
    • G01N21/90Investigating the presence of flaws or contamination in a container or its contents

Definitions

  • the present invention relates to an apparatus and a method for checking objects for pharmaceutical applications.
  • tubs plastic transport troughs
  • the objects in particular different types of containers, can be arranged directly in the transport trays or holding devices for the objects (so-called nests) are provided, in which the objects are arranged.
  • the objects are usually used for packaging of pharmaceutical applications, in particular liquid or
  • the objects are manufactured or recycled objects are cleaned and placed in the transport trays. Thereafter, the transport trays are pre-sterilized and then closed with a cover sheet or a lid. In pharmaceutical companies, the transport trays are then reopened and the objects are filled. It may happen that during transport and / or storage of the
  • the objects may be damaged, or e.g. for objects with attached front closures, such as
  • Needle caps or plugs may loosen. This may lead to undesired complications due to damaged objects or missing in the subsequent filling step
  • Processing step can be used. This is inventively achieved in that this arrangement is a movement device with a
  • Gripping unit a transport tray, in which at least one object is arranged, and an optical control device comprises.
  • Control device checks the objects before further processing.
  • Control can take place when the objects are still arranged in the transport tray and / or when the objects from the transport tray
  • the optical control device is arranged movable.
  • the optical control device for example via the
  • Transport tub to be driven to control the objects.
  • the objects removed by means of the moving device and the optical control device can both be moved relative to one another in order to carry out the optical control.
  • the arrangement further comprises a holding device, which in the
  • Transport tray is arranged in a removable manner and which holds the objects.
  • Such holding devices are also referred to as nests.
  • the holding device has the advantage that the objects simply by gripping the
  • Holding device can be removed from the transport tray.
  • the objects are preferably containers for containing pharmaceutical substances, such as vials, cartridges, ampoules or syringes with or without needle guard such as e.g. Nuer-Lock adapters, closures, piston plugs,
  • the transport trough is preferably covered by a covering device, wherein the covering device is, for example, a foil or a lid which closes the transport trough.
  • Transport tray made of a transparent material.
  • Transport tray are arranged. This has the particular advantage that a review of the objects is possible faster because the step of removing the objects for control is eliminated. After checking, the objects are simply removed and immediately forwarded to the next process step or the objects in the transport trough further processed.
  • optical control device preferably all optoelectronic devices, e.g. Cameras, scanners, optical sensors or the like., Can be used.
  • the present invention relates to a method for checking objects for pharmaceutical applications, which allows automated control of the objects.
  • a transport trough is supplied, which is preferably closed by means of a covering device, wherein the objects to be tested are arranged in the transport trough.
  • the evaluation of the optical signals obtained takes place in a control unit which optionally outputs an error message if objects deviate from a designated state, ie if the objects are damaged, if objects are missing or if objects are not arranged in the correct position or if parts of objects such as eg Cover caps or the like, missing.
  • Automation can be the verification of all objects before one
  • the objects are preferably checked if they are still in the
  • Transport tray are arranged or alternatively, the objects are removed from the transport tray and then visually checked.
  • the objects are particularly preferably containers for receiving pharmaceutical products, such as pharmaceutical liquids or powders.
  • the objects are particularly preferably arranged in a holding device, so that the objects on the holding device from the
  • Transport tray can be removed, whereby a quick and easy removal operation from the transport tray is possible.
  • Figure 1 is a schematic representation of an arrangement according to a first embodiment of the invention.
  • Figure 2 is a schematic representation of an arrangement according to a second embodiment of the invention. Embodiment of the invention
  • the arrangement 1 comprises a
  • Movement device 2 which is a multi-axis robotic arm in this embodiment.
  • the movement device 2 may be a
  • a gripping unit 3 is arranged.
  • the arrangement 1 further comprises a transport trough 4, which is provided for transporting a plurality of objects 5.
  • the objects 5 are received in a holding device 9.
  • the arrangement further comprises an optical control device 7, which in this embodiment comprises a camera 8.
  • a surveillance area of the camera 8 is indicated in FIG. 1 by dashed lines.
  • closures 6 are attached in the form of caps.
  • the transport trough 4 is supplied by means of a feed device, not shown.
  • the transport trough 4 in this embodiment is preferably provided with a cover, such as e.g. a foil or a lid closed. Before being supplied to the test arrangement according to the invention, this cover is automatically removed by means of an opening unit (not shown).
  • Figure 1 shows the state in which the cover has already been removed and the objects 5 are removed from the transport tray 4.
  • a covering device for example a foil, of which
  • transport tub 4 removed.
  • the transport tray 4 is open, so that from above on the arranged in the holding device 9 objects 5 can be accessed.
  • the gripping unit 3 acts on the holding device 9 and thus removes the holding device together with the objects held therein 5 (double arrow A). This condition is shown in FIG.
  • the holding device 9 is pivoted about the camera 8 (double arrow B), so that a review of the objects 5 can be performed. Since in this embodiment the objects 5 are closed with a shutter 6, the optical control device 7 checks next to one
  • closures are optical
  • the movement device 2 moves the holding device 9 together with the objects 5 to a next processing step, in particular a filling of the objects, since the transport trough 4 was usually closed under sterile conditions and the opening and the optical inspection the objects 5 also takes place in a sterile clean room.
  • an automatic inspection of objects for pharmaceutical applications can be carried out without the need for manual intervention by an employee. If the optical control device 7 detects a deviation from the specifications, for example, a warning signal or an error message is output, so that the affected holding device 9 can be removed from the production process. This can be avoided that, for example, damaged objects are filled, the filling product would flow out of the damaged objects and pollute the clean room. Alternatively, a position of a defective object can be determined by means of the optical control device 7 and forwarded to a subsequent device. As a further alternative, the faulty object can also be removed.
  • the arrangement according to the invention provides a simple and inexpensive
  • the arrangement of the second embodiment substantially corresponds to that of the first embodiment, in contrast to the optical control device 7 is arranged to be movable.
  • the optical control device 7, as indicated by the arrows C, D and E, are moved in the horizontal and vertical directions and pivoted about a pivot point in the horizontal direction. This is a
  • Moving device 2 possible, so that it is no longer necessary that the moving device 2 must move the objects to be tested exclusively on the optical control device 7, but that the optical control device 7 can travel a certain distance.
  • the transport tray 4 is preferably made of a transparent Material produced, for example, a transparent plastic or glass, so that a review by the transport tray 4 through is possible. It should be noted that it is also possible that the transport tray 4 then remains closed and will be opened only after successful positive optical inspection.

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Investigating Materials By The Use Of Optical Means Adapted For Particular Applications (AREA)

Abstract

L'invention concerne un procédé et un agencement servant à contrôler des objets (5) pour des applications pharmaceutiques, comprenant un dispositif de déplacement (2) avec une unité de préhension (3), un carter de transport (4) qui peut être en particulier fermé par un dispositif de couvercle, un ou une pluralité d'objets (5) qui sont agencés dans le carter de transport (4), et un équipement de contrôle optique (7) qui contrôle optiquement les objets (5).
EP11709090A 2010-05-07 2011-03-09 Procédé et dispositif de contrôle d'objets pour applications pharmaceutiques Withdrawn EP2567220A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102010028715.6A DE102010028715B4 (de) 2010-05-07 2010-05-07 Vorrichtung und Verfahren zur Überprüfung von Objekten für pharmazeutische Anwendungen
PCT/EP2011/053556 WO2011138072A1 (fr) 2010-05-07 2011-03-09 Procédé et dispositif de contrôle d'objets pour applications pharmaceutiques

Publications (1)

Publication Number Publication Date
EP2567220A1 true EP2567220A1 (fr) 2013-03-13

Family

ID=43901476

Family Applications (1)

Application Number Title Priority Date Filing Date
EP11709090A Withdrawn EP2567220A1 (fr) 2010-05-07 2011-03-09 Procédé et dispositif de contrôle d'objets pour applications pharmaceutiques

Country Status (4)

Country Link
EP (1) EP2567220A1 (fr)
CN (1) CN102884420B (fr)
DE (1) DE102010028715B4 (fr)
WO (1) WO2011138072A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103884647B (zh) * 2012-12-20 2015-12-30 山东新华医疗器械股份有限公司 自动灯检机的压瓶装置
DE102014201961B4 (de) 2014-02-04 2024-09-26 Syntegon Technology Gmbh Vorrichtung und Verfahren zur Vorbereitung der Entnahme von Behältnissen aus einem von einem Tablett verschlossenen Tray
DE102014221029B4 (de) 2014-10-16 2023-03-30 Syntegon Technology Gmbh Überwachungseinheit zum Überwachen von Objekten für pharmazeutische Anwendungen, insbesondere Stopfen für Behältnisse

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2816432B2 (ja) 1989-07-17 1998-10-27 東芝メカトロニクス株式会社 錠剤パッケージの検査装置
DE4122953A1 (de) 1991-07-11 1993-01-14 Nahrungsguetermaschbau Gmbh Vorrichtung zum aufnehmen und freigeben von stueckguetern
WO1997032665A1 (fr) 1996-03-07 1997-09-12 C.A. Greiner & Söhne Gesellschaft Mbh Contenant collecteur pour unites consommables empilables
DE29712307U1 (de) 1997-07-14 1997-08-28 Ringoplast Gmbh, 49824 Ringe Lager- und Transporteinrichtung für Gläser, Becher, Dosen o.dgl.
DE19929532C2 (de) 1999-06-28 2002-12-05 Sanacorp Ag Plombierung eines wiederverwendbaren, aus Behälterwanne und Deckel bestehenden Transportbehälters
DE10230524A1 (de) 2002-07-05 2004-01-15 Robert Bosch Gmbh Transportbehälter für zylindrische pharmazeutische Behältnisse wie Ampullen, Vials o. ä. sowie Transporteinheit und Entnahmesystem für Transportbehälter
CN1529165A (zh) * 2003-09-25 2004-09-15 谢森林 全自动瓶装药剂检测机
US7028723B1 (en) 2003-11-03 2006-04-18 Alouani Ali Tahar Apparatus and method for automatic prescription verification
TWI356036B (en) 2004-06-09 2012-01-11 Smithkline Beecham Corp Apparatus and method for pharmaceutical production
AT501313B1 (de) 2005-02-01 2009-07-15 Stiwa Holding Gmbh Haltevorrichtung für zylindrische gegenstände, insbesondere rohrförmige probenbehälter
CH697416B1 (de) 2005-02-04 2008-09-30 Koenig Maschb Ag Handhabungssystem.
DE202007012882U1 (de) 2007-09-14 2007-12-06 Ernst Schausberger & Co. Gmbh Verpackungs- und Transportbehälter und Zuschnitt hierfür
CN201277954Y (zh) * 2008-10-30 2009-07-22 西安毅达信息系统有限公司 一种安瓿瓶药剂检测系统

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
None *
See also references of WO2011138072A1 *

Also Published As

Publication number Publication date
CN102884420B (zh) 2015-02-18
CN102884420A (zh) 2013-01-16
WO2011138072A1 (fr) 2011-11-10
DE102010028715A1 (de) 2011-11-10
DE102010028715B4 (de) 2024-05-29

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