EP2521522B1 - Verfahren für den nachweis von analyten in einer körperflüssigkeit - Google Patents
Verfahren für den nachweis von analyten in einer körperflüssigkeit Download PDFInfo
- Publication number
- EP2521522B1 EP2521522B1 EP10810770.7A EP10810770A EP2521522B1 EP 2521522 B1 EP2521522 B1 EP 2521522B1 EP 10810770 A EP10810770 A EP 10810770A EP 2521522 B1 EP2521522 B1 EP 2521522B1
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- EP
- European Patent Office
- Prior art keywords
- detector
- dressing
- metabolite
- body fluid
- polymer
- Prior art date
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- 239000002759 woven fabric Substances 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive plasters or dressings
- A61F13/0203—Adhesive plasters or dressings having a fluid handling member
- A61F13/0213—Adhesive plasters or dressings having a fluid handling member the fluid handling member being a layer of hydrocoloid, gel forming material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive plasters or dressings
- A61F13/0203—Adhesive plasters or dressings having a fluid handling member
- A61F13/0226—Adhesive plasters or dressings having a fluid handling member characterised by the support layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/56—Wetness-indicators or colourants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive plasters or dressings
- A61F13/0273—Adhesive bandages for winding around limb, trunk or head, e.g. cohesive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F2013/00361—Plasters
- A61F2013/00365—Plasters use
- A61F2013/00429—Plasters use for conducting tests
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F2013/00361—Plasters
- A61F2013/00846—Plasters with transparent or translucent part
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F2013/00361—Plasters
- A61F2013/00902—Plasters containing means
- A61F2013/0094—Plasters containing means for sensing physical parameters
- A61F2013/00965—Plasters containing means for sensing physical parameters microbiological activity
Claims (13)
- Verfahren zum Nachweis eines Analyten in einer Körperflüssigkeit (2), dadurch gekennzeichnet, dass ein Detektor (6) oberhalb eines Bereiches der Haut (4) einer Person oder eines Tiers, die bzw. das die Körperflüssigkeit (2) enthält, platziert wird, dass anschließend wenigstens ein Metabolit, welcher aus dem Stoffwechsel oder aus dem Abbau des Analyten hervorgegangen ist, einzig in gasförmiger Form durch Inkontaktbringen des Detektors (6) mit dem gasförmigen Metaboliten nachgewiesen wird, wobei der gasförmige Metabolit aus der Verdampfung wenigstens eines Teils des Metaboliten hervorgegangen ist und das Inkontaktbringen ein optisch nachweisbares Signal erzeugt, und dass der Nachweis ohne Kontakt zwischen der Körperflüssigkeit (2) und dem Detektor (6) vollzogen wird.
- Nachweisverfahren nach Anspruch 1, dadurch gekennzeichnet, dass der Detektor (6) aus einem chromogenen Detektor und einem fluorogenen Detektor ausgewählt ist.
- Nachweisverfahren nach einem der Ansprüche 1 und 2, dadurch gekennzeichnet, dass ein eingeschlossener Raum (5) durch Aufbringen eines den Detektor (6) umfassenden Einschließungselements auf einen Bereich der Haut (4) einer Person oder eines Tiers, die bzw. das Körperflüssigkeit (2) enthält, gebildet wird.
- Nachweisverfahren nach Anspruch 3, dadurch gekennzeichnet, dass das Einschließungselement einen Verband (1) umfasst.
- Nachweisverfahren nach einem der Ansprüche 1 bis 4, dadurch gekennzeichnet, dass die Körperflüssigkeit (2) durch aus einer Wunde (3) der Haut (4) einer Person oder eines Tiers stammendes Exsudat gebildet ist.
- Nachweisverfahren nach einem der Ansprüche 1 bis 5, dadurch gekennzeichnet, dass der Detektor (6) eine gegenüber dem Metaboliten empfindliche Sonde und einen Träger umfasst.
- Nachweisverfahren nach Anspruch 6, dadurch gekennzeichnet, dass die Sonde in den Träger integriert ist.
- Nachweisverfahren nach Anspruch 6, dadurch gekennzeichnet, dass die Sonde durch kovalente Bindung mit dem Träger verbunden ist.
- Nachweisverfahren nach einem der Ansprüche 6 bis 8, dadurch gekennzeichnet, dass der Träger für den Metaboliten in gasförmiger Form durchlässig ist.
- Nachweisverfahren nach einem der Ansprüche 6 bis 9, dadurch gekennzeichnet, dass der Träger transparent oder durchscheinend ist.
- Nachweisverfahren nach einem der Ansprüche 6 bis 10, dadurch gekennzeichnet, dass der Träger ein Polymer ist.
- Nachweisverfahren nach Anspruch 11, dadurch gekennzeichnet, dass das Polymer porös ist und eine spezifische Oberfläche von mehr als oder gleich 50 m2/g aufweist.
- Nachweisverfahren nach Anspruch 11, dadurch gekennzeichnet, dass das Polymer aus einem Alginat, einem Hydrogel, einem Gelpolymer auf der Basis von Silikonöl und einem fluorierten Gelpolymer ausgewählt ist.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1000007A FR2954911A1 (fr) | 2010-01-04 | 2010-01-04 | Procede de detection d'un analyte dans un fluide corporel |
| PCT/FR2010/000882 WO2011080427A1 (fr) | 2010-01-04 | 2010-12-29 | PROCÉDÉ DE DÉTECTION D'UN ANALYTE DANS UN FLUIDE CORPOREL ET PANSEMENT POUR LA MISE EN œUVRE D'UN TEL PROCÉDÉ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP2521522A1 EP2521522A1 (de) | 2012-11-14 |
| EP2521522B1 true EP2521522B1 (de) | 2014-05-28 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP10810770.7A Active EP2521522B1 (de) | 2010-01-04 | 2010-12-29 | Verfahren für den nachweis von analyten in einer körperflüssigkeit |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9551701B2 (de) |
| EP (1) | EP2521522B1 (de) |
| JP (1) | JP2013516203A (de) |
| CN (1) | CN102781381B (de) |
| FR (1) | FR2954911A1 (de) |
| WO (1) | WO2011080427A1 (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1922045B1 (de) | 2005-09-07 | 2012-11-07 | Tyco Healthcare Group LP | Abgeschlossener wundverband mit mikropumpe |
| DE102010001855A1 (de) * | 2010-02-11 | 2011-08-11 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V., 80686 | Verbandsmaterial zur Überwachung einer Wundheilung |
| CN107252383A (zh) | 2011-07-14 | 2017-10-17 | 史密夫及内修公开有限公司 | 伤口敷料和治疗方法 |
| FR2988608B1 (fr) | 2012-03-30 | 2014-09-05 | Commissariat Energie Atomique | Materiau, son procede de preparation et ses utilisations |
| DK3354293T3 (da) | 2012-05-23 | 2020-02-17 | Smith & Nephew | Apparater til sårbehandling ved negativt tryk |
| US10667955B2 (en) | 2012-08-01 | 2020-06-02 | Smith & Nephew Plc | Wound dressing and method of treatment |
| CN104661626B (zh) | 2012-08-01 | 2018-04-06 | 史密夫及内修公开有限公司 | 伤口敷料 |
| TW201622668A (zh) * | 2014-12-16 | 2016-07-01 | 準訊生醫股份有限公司 | 長效型貼片敷料結構 |
| US11832801B2 (en) * | 2016-07-11 | 2023-12-05 | Arizona Board Of Regents On Behalf Of Arizona State University | Sweat as a biofluid for analysis and disease identification |
| GB201614053D0 (en) * | 2016-08-17 | 2016-09-28 | Microarray Ltd | Determining the condition of a wound |
| EP3292845B1 (de) * | 2016-09-08 | 2019-08-14 | Sefar AG | Indikatorauflage und verfahren zum anzeigen einer verkeimung bei einer wunde |
| GB2555584B (en) | 2016-10-28 | 2020-05-27 | Smith & Nephew | Multi-layered wound dressing and method of manufacture |
| DE102017106570A1 (de) * | 2017-03-28 | 2018-10-04 | Cinogy Gmbh | Flächige flexible Auflageanordnung |
| CA3059516A1 (en) * | 2017-04-11 | 2018-10-18 | Smith & Nephew Plc | Component positioning and stress relief for sensor enabled wound dressings |
| KR102161135B1 (ko) * | 2018-06-26 | 2020-09-29 | 동양미래대학교 산학협력단 | 대소변 구별 감지시트 |
| TWI668444B (zh) * | 2018-07-17 | 2019-08-11 | 淡江大學 | 檢測裝置及檢測系統 |
| US11813926B2 (en) | 2020-08-20 | 2023-11-14 | Denso International America, Inc. | Binding agent and olfaction sensor |
| US11760170B2 (en) | 2020-08-20 | 2023-09-19 | Denso International America, Inc. | Olfaction sensor preservation systems and methods |
| US11881093B2 (en) | 2020-08-20 | 2024-01-23 | Denso International America, Inc. | Systems and methods for identifying smoking in vehicles |
| US11828210B2 (en) | 2020-08-20 | 2023-11-28 | Denso International America, Inc. | Diagnostic systems and methods of vehicles using olfaction |
| US11932080B2 (en) | 2020-08-20 | 2024-03-19 | Denso International America, Inc. | Diagnostic and recirculation control systems and methods |
| US11760169B2 (en) | 2020-08-20 | 2023-09-19 | Denso International America, Inc. | Particulate control systems and methods for olfaction sensors |
| US11636870B2 (en) | 2020-08-20 | 2023-04-25 | Denso International America, Inc. | Smoking cessation systems and methods |
| WO2022099021A1 (en) * | 2020-11-08 | 2022-05-12 | Sensill, Inc. | Devices, methods, and systems to collect, store, and analyze chemical substances |
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| JPS5877661A (ja) * | 1981-11-02 | 1983-05-11 | Fuji Photo Film Co Ltd | アンモニアまたはアンモニア生成基質分析用一体型多層分析材料および検出法 |
| US4732153A (en) * | 1984-07-18 | 1988-03-22 | Michael Phillips | Transdermal dosimeter |
| US5445147A (en) * | 1988-09-08 | 1995-08-29 | Sudor Partners | Method and apparatus for determination of chemical species in body fluid |
| US5899856A (en) * | 1988-09-08 | 1999-05-04 | Sudormed, Inc. | Dermal patch detecting long-term alcohol consumption and method of use |
| US5181905A (en) | 1989-11-28 | 1993-01-26 | Eric Flam | Method of monitoring the condition of the skin or wound |
| NZ235934A (en) * | 1989-11-28 | 1992-09-25 | Squibb & Sons Inc | Adhesive medical dressing containing a hydrocolloid and having a temperature-sensing liquid crystal tape on the backing layer |
| US5660790A (en) | 1996-08-13 | 1997-08-26 | Litmus Concepts, Inc. | PH and amine test elements |
| GB9718923D0 (en) * | 1997-09-05 | 1997-11-12 | T G Eakin Limited | Wound dressing |
| GB0025084D0 (en) * | 2000-10-13 | 2000-11-29 | Cambridge Meditech | Improvements in detection |
| US6981947B2 (en) * | 2002-01-22 | 2006-01-03 | University Of Florida Research Foundation, Inc. | Method and apparatus for monitoring respiratory gases during anesthesia |
| US20040126897A1 (en) | 2002-12-19 | 2004-07-01 | 3M Innovative Properties Company | Colorimetric sensors constructed of diacetylene materials |
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| DE102004001594B4 (de) * | 2004-01-09 | 2006-09-21 | Bio-Gate Ag | Wundauflage und Verfahren zu deren Herstellung |
| JP4505296B2 (ja) * | 2004-09-17 | 2010-07-21 | 富士フイルム株式会社 | 液体試料分析用多層分析素子 |
| US8852515B2 (en) | 2004-09-17 | 2014-10-07 | Fujifilm Corporation | Multilayer analysis element for analyzing liquid samples |
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| JP5042209B2 (ja) * | 2005-03-24 | 2012-10-03 | ノーラブズ エービー | 酸化窒素による美容治療、前記治療を実施する装置、及びその製造方法 |
| US20070142762A1 (en) * | 2005-12-16 | 2007-06-21 | Eastman Kodak Company | Wound dressing |
| US8256286B2 (en) * | 2009-04-24 | 2012-09-04 | Sober Steering Sensors, Llc | System and method for detecting and measuring ethyl alcohol in the blood of a motorized vehicle driver transdermally and non-invasively in the presence of interferents |
-
2010
- 2010-01-04 FR FR1000007A patent/FR2954911A1/fr not_active Withdrawn
- 2010-12-29 EP EP10810770.7A patent/EP2521522B1/de active Active
- 2010-12-29 JP JP2012546483A patent/JP2013516203A/ja active Pending
- 2010-12-29 US US13/520,078 patent/US9551701B2/en active Active
- 2010-12-29 CN CN201080065147.9A patent/CN102781381B/zh active Active
- 2010-12-29 WO PCT/FR2010/000882 patent/WO2011080427A1/fr active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| JP2013516203A (ja) | 2013-05-13 |
| CN102781381A (zh) | 2012-11-14 |
| US20120283529A1 (en) | 2012-11-08 |
| CN102781381B (zh) | 2015-01-07 |
| EP2521522A1 (de) | 2012-11-14 |
| WO2011080427A1 (fr) | 2011-07-07 |
| FR2954911A1 (fr) | 2011-07-08 |
| US9551701B2 (en) | 2017-01-24 |
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