EP2471556A4 - Kontrastmittel für photoakustische bildgebung und verfahren für photoakustische bildgebung damit - Google Patents

Kontrastmittel für photoakustische bildgebung und verfahren für photoakustische bildgebung damit

Info

Publication number
EP2471556A4
EP2471556A4 EP10821738.1A EP10821738A EP2471556A4 EP 2471556 A4 EP2471556 A4 EP 2471556A4 EP 10821738 A EP10821738 A EP 10821738A EP 2471556 A4 EP2471556 A4 EP 2471556A4
Authority
EP
European Patent Office
Prior art keywords
photoacoustic imaging
contrast agent
method utilizing
utilizing same
imaging method
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP10821738.1A
Other languages
English (en)
French (fr)
Other versions
EP2471556A1 (de
Inventor
Fumio Yamauchi
Satoshi Ogawa
Kengo Kanazaki
Sachiko Inoue
Tatsuki Fukui
Masato Minami
Mayuko Kishi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Canon Inc
Original Assignee
Canon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Canon Inc filed Critical Canon Inc
Publication of EP2471556A1 publication Critical patent/EP2471556A1/de
Publication of EP2471556A4 publication Critical patent/EP2471556A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
    • A61K47/6855—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from breast cancer cell
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/225—Microparticles, microcapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/226—Solutes, emulsions, suspensions, dispersions, semi-solid forms, e.g. hydrogels
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acoustics & Sound (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
EP10821738.1A 2009-10-05 2010-10-05 Kontrastmittel für photoakustische bildgebung und verfahren für photoakustische bildgebung damit Withdrawn EP2471556A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2009231994 2009-10-05
JP2010144322 2010-06-24
PCT/JP2010/005958 WO2011043061A1 (ja) 2009-10-05 2010-10-05 光音響イメージング用造影剤、及び、それを用いた光音響イメージング方法

Publications (2)

Publication Number Publication Date
EP2471556A1 EP2471556A1 (de) 2012-07-04
EP2471556A4 true EP2471556A4 (de) 2015-06-03

Family

ID=43856545

Family Applications (1)

Application Number Title Priority Date Filing Date
EP10821738.1A Withdrawn EP2471556A4 (de) 2009-10-05 2010-10-05 Kontrastmittel für photoakustische bildgebung und verfahren für photoakustische bildgebung damit

Country Status (5)

Country Link
US (1) US20110117023A1 (de)
EP (1) EP2471556A4 (de)
JP (1) JPWO2011043061A1 (de)
CN (1) CN102573925B (de)
WO (1) WO2011043061A1 (de)

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US6136311A (en) 1996-05-06 2000-10-24 Cornell Research Foundation, Inc. Treatment and diagnosis of cancer
US7750536B2 (en) 2006-03-02 2010-07-06 Visualsonics Inc. High frequency ultrasonic transducer and matching layer comprising cyanoacrylate
US8940871B2 (en) 2006-03-20 2015-01-27 The Regents Of The University Of California Engineered anti-prostate stem cell antigen (PSCA) antibodies for cancer targeting
JP6126773B2 (ja) 2007-09-04 2017-05-10 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 癌のターゲッティングおよび検出のための高親和性抗前立腺幹細胞抗原（ｐｓｃａ）抗体
EP2740490A1 (de) * 2007-10-03 2014-06-11 Cornell University Behandlung von proliferativen Erkrankungen mit PSMA-Antikörpern
ES2712732T3 (es) 2009-02-17 2019-05-14 Cornell Res Foundation Inc Métodos y kits para el diagnóstico de cáncer y la predicción de valor terapéutico
EP2506876B1 (de) 2009-12-02 2016-10-12 Imaginab, Inc. J591-minikörper und cys-diakörper zur adressierung des prostataspezifischen membranantigens (psma) und verfahren zu deren verwendung
JP6234064B2 (ja) * 2012-05-23 2017-11-22 キヤノン株式会社 重合体、前記重合体を用いた核磁気共鳴分析用または磁気共鳴イメージング用の造影剤、化合物、前記重合体を用いた核磁気共鳴分析方法および磁気共鳴イメージング方法
JP6195339B2 (ja) * 2012-07-10 2017-09-13 キヤノン株式会社 粒子及び前記粒子を有する光音響用造影剤
US20150313994A1 (en) * 2012-09-12 2015-11-05 University Of Tsukuba Surface-modified iron oxide particles for cancer ablation
US9155804B2 (en) 2012-09-26 2015-10-13 General Electric Company Contrast enhancement agents and method of use thereof
CN111495721B (zh) 2014-03-12 2021-08-13 富士胶片索诺声公司 具有带集成中心匹配层的超声透镜的高频超声换能器
JP6590503B2 (ja) 2015-04-01 2019-10-16 キヤノン株式会社 光音響装置および情報取得装置
US10743770B2 (en) 2015-05-26 2020-08-18 Canon Kabushiki Kaisha Photoacoustic device
EP4137158A1 (de) 2015-08-07 2023-02-22 Imaginab, Inc. Gegen moleküle gerichtete antigenbindende konstrukte
CN108395480A (zh) * 2017-02-08 2018-08-14 广州百尼夫生物科技有限公司 嵌合抗原受体及其基因和重组表达载体、carher2-nkt细胞及其制备方法和应用
WO2018147960A1 (en) 2017-02-08 2018-08-16 Imaginab, Inc. Extension sequences for diabodies
JP2018134073A (ja) * 2017-02-21 2018-08-30 東ソー株式会社 未分化細胞吸着剤、および細胞の分離方法
CN106955362B (zh) * 2017-03-08 2020-08-07 上海师范大学 纳米探针在制备肿瘤靶向光声成像信号药物中的应用
CN110354281B (zh) * 2019-06-20 2021-09-24 中南大学湘雅医院 一种双靶向多模态分子影像探针及其制备方法和应用

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WO2009049083A1 (en) * 2007-10-09 2009-04-16 Washington University In St. Louis Particles for imaging

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US5262176A (en) 1986-07-03 1993-11-16 Advanced Magnetics, Inc. Synthesis of polysaccharide covered superparamagnetic oxide colloids
US6217848B1 (en) * 1999-05-20 2001-04-17 Mallinckrodt Inc. Cyanine and indocyanine dye bioconjugates for biomedical applications
ATE422880T1 (de) * 2003-08-26 2009-03-15 Smithkline Beecham Corp Heterofunktionelle copolymere von glycerol und polyethylenglykol, ihre konjugate und zusammensetzungen
CN100452254C (zh) * 2004-12-02 2009-01-14 北京大学 四氧化三铁磁流体及其制备方法和应用
KR20080104928A (ko) * 2007-05-29 2008-12-03 율촌화학 주식회사 암의 진단과 치료를 동시에 수행하는 항암제
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US8773126B2 (en) * 2007-09-07 2014-07-08 Canon Kabushiki Kaisha Nuclear magnetic resonance measuring method using an isotope-labeled compound
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JP2009231994A (ja) 2008-03-20 2009-10-08 Brother Ind Ltd ファクシミリ通信システムおよびファクシミリ装置
US8652441B2 (en) * 2009-10-05 2014-02-18 Canon Kabushiki Kaisha Contrast agent for photoacoustic imaging and photoacoustic imaging method
JP4837107B2 (ja) 2010-02-04 2011-12-14 旭化成せんい株式会社 エアバッグ用基布およびエアバッグ

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WO2009049083A1 (en) * 2007-10-09 2009-04-16 Washington University In St. Louis Particles for imaging

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CHUNGANG WANG ET AL: "Gold nanorod/Fe304 nanoparticle nano-pearl-necklaces for simultaneous targeting, dual-mode imaging, and photothermal ablation of cancer cells", ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, VCH VERLAG, WEINHEIM, DE, vol. 48, 1 January 2009 (2009-01-01), pages 2759 - 2763, XP008170220, ISSN: 0570-0833 *
COPLAND J A ET AL: "Bioconjugated gold nanoparticles as a molecular based contrast agent: implications for imaging of deep tumors using optoacoustic tomography", MOLECULAR IMAGING & BIOLOGY, ELSEVIER, BOSTON, vol. 6, no. 5, 1 September 2004 (2004-09-01), pages 341 - 349, XP004570390, ISSN: 1536-1632, DOI: 10.1016/J.MIBIO.2004.06.002 *
MALLIDI S ET AL: "Ultrasound-based imaging of nanoparticles: From molecular and cellular imaging to therapy guidance", ULTRASONICS SYMPOSIUM (IUS), 2009 IEEE INTERNATIONAL, IEEE, PISCATAWAY, NJ, USA, 20 September 2009 (2009-09-20), pages 27 - 36, XP031654390, ISBN: 978-1-4244-4389-5 *
SOPHIE LAURENT ET AL: "Magnetic Iron Oxide Nanoparticles: Synthesis, Stabilization, Vectorization, Physicochemical Characterizations, and Biological Applications", CHEMICAL REVIEWS, vol. 108, no. 6, 1 June 2008 (2008-06-01), pages 2064 - 2110, XP055158397, ISSN: 0009-2665, DOI: 10.1021/cr068445e *
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Also Published As

Publication number Publication date
CN102573925B (zh) 2015-08-05
CN102573925A (zh) 2012-07-11
US20110117023A1 (en) 2011-05-19
JPWO2011043061A1 (ja) 2013-03-04
WO2011043061A1 (ja) 2011-04-14
EP2471556A1 (de) 2012-07-04

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