EP2438438A4 - Ensuring sample adequacy using turbidity light scattering techniques - Google Patents

Ensuring sample adequacy using turbidity light scattering techniques Download PDF

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Publication number
EP2438438A4
EP2438438A4 EP09845651.0A EP09845651A EP2438438A4 EP 2438438 A4 EP2438438 A4 EP 2438438A4 EP 09845651 A EP09845651 A EP 09845651A EP 2438438 A4 EP2438438 A4 EP 2438438A4
Authority
EP
European Patent Office
Prior art keywords
light scattering
scattering techniques
sample adequacy
turbidity light
ensuring sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP09845651.0A
Other languages
German (de)
French (fr)
Other versions
EP2438438B1 (en
EP2438438A1 (en
Inventor
Jonathan Matthew Miller
Carl Theodore Edens
Jiulin Xia
Richard L. Mantefuel
Nadia P. Allen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Qiagen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Qiagen filed Critical Qiagen
Publication of EP2438438A1 publication Critical patent/EP2438438A1/en
Publication of EP2438438A4 publication Critical patent/EP2438438A4/en
Application granted granted Critical
Publication of EP2438438B1 publication Critical patent/EP2438438B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/06—Test-tube stands; Test-tube holders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/51—Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00594—Quality control, including calibration or testing of components of the analyser
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/025—Align devices or objects to ensure defined positions relative to each other
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0829—Multi-well plates; Microtitration plates
    • G01N15/075—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465—Separating and mixing arrangements
    • G01N2035/00524—Mixing by agitating sample carrier
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465—Separating and mixing arrangements
    • G01N2035/00534—Mixing by a special element, e.g. stirrer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
EP09845651.0A 2009-06-03 2009-11-12 Ensuring sample adequacy using turbidity light scattering techniques Active EP2438438B1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US18385709P 2009-06-03 2009-06-03
US24262809P 2009-09-15 2009-09-15
US12/588,305 US8877507B2 (en) 2007-04-06 2009-10-09 Ensuring sample adequacy using turbidity light scattering techniques
PCT/US2009/064268 WO2010141040A1 (en) 2009-06-03 2009-11-12 Ensuring sample adequacy using turbidity light scattering techniques

Publications (3)

Publication Number Publication Date
EP2438438A1 EP2438438A1 (en) 2012-04-11
EP2438438A4 true EP2438438A4 (en) 2017-11-22
EP2438438B1 EP2438438B1 (en) 2019-07-10

Family

ID=43297996

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09845651.0A Active EP2438438B1 (en) 2009-06-03 2009-11-12 Ensuring sample adequacy using turbidity light scattering techniques

Country Status (8)

Country Link
US (1) US8877507B2 (en)
EP (1) EP2438438B1 (en)
JP (1) JP5542922B2 (en)
AU (1) AU2009347207B2 (en)
CA (1) CA2764237C (en)
ES (1) ES2737403T3 (en)
TW (1) TWI486570B (en)
WO (1) WO2010141040A1 (en)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8355132B2 (en) 2007-04-06 2013-01-15 Qiagen Gaithersburg, Inc. Sample adequacy measurement system having a plurality of sample tubes and using turbidity light scattering techniques
US8703492B2 (en) 2007-04-06 2014-04-22 Qiagen Gaithersburg, Inc. Open platform hybrid manual-automated sample processing system
CA3170924A1 (en) 2007-10-02 2009-04-09 Labrador Diagnostics Llc Modular point-of-care devices and uses thereof
WO2011063139A1 (en) 2009-11-18 2011-05-26 Qiagen Laboratory central control unit method and system
US8542353B2 (en) 2010-09-30 2013-09-24 Precision Energy Services, Inc. Refractive index sensor for fluid analysis
US8411262B2 (en) * 2010-09-30 2013-04-02 Precision Energy Services, Inc. Downhole gas breakout sensor
BR112013018656B1 (en) 2011-01-21 2021-03-02 Labrador Diagnostics Llc method for detecting the presence or concentration of an analyte in a sample of fluid contained in a container, and, method of measuring the concentration of analyte in a sample of fluid
JP2014522968A (en) * 2011-07-05 2014-09-08 ベーリンガー インゲルハイム マイクロパーツ ゲゼルシャフト ミット ベシュレンクテル ハフツング Method for measuring scattered light of particles in a medium
TWI648532B (en) 2011-08-29 2019-01-21 美商安美基公司 Method and apparatus for non-destructive detection - undissolved particles in a fluid
US20140170735A1 (en) 2011-09-25 2014-06-19 Elizabeth A. Holmes Systems and methods for multi-analysis
US9664702B2 (en) 2011-09-25 2017-05-30 Theranos, Inc. Fluid handling apparatus and configurations
US9632102B2 (en) 2011-09-25 2017-04-25 Theranos, Inc. Systems and methods for multi-purpose analysis
US9268915B2 (en) 2011-09-25 2016-02-23 Theranos, Inc. Systems and methods for diagnosis or treatment
US8475739B2 (en) 2011-09-25 2013-07-02 Theranos, Inc. Systems and methods for fluid handling
US10012664B2 (en) 2011-09-25 2018-07-03 Theranos Ip Company, Llc Systems and methods for fluid and component handling
US9250229B2 (en) 2011-09-25 2016-02-02 Theranos, Inc. Systems and methods for multi-analysis
US9810704B2 (en) 2013-02-18 2017-11-07 Theranos, Inc. Systems and methods for multi-analysis
US9803239B2 (en) * 2012-03-29 2017-10-31 Complete Genomics, Inc. Flow cells for high density array chips
WO2014093838A2 (en) * 2012-12-14 2014-06-19 The J. David Gladstone Institutes Automated robotic microscopy systems
US9400285B2 (en) 2013-03-15 2016-07-26 Abbot Laboratories Automated diagnostic analyzers having vertically arranged carousels and related methods
EP4354149A2 (en) 2013-03-15 2024-04-17 Abbott Laboratories Diagnostic analyzers with pretreatment carousels and related methods
CN114137240A (en) 2013-03-15 2022-03-04 雅培制药有限公司 Automated diagnostic analyzer with rear accessible track system and related methods
JP2015010836A (en) * 2013-06-26 2015-01-19 栗田工業株式会社 Concentration measurement apparatus for dissolved component
JP6348976B2 (en) * 2014-06-11 2018-06-27 オリンパス株式会社 Sample evaluation method
JP2016080403A (en) * 2014-10-10 2016-05-16 国立大学法人大阪大学 Liquid inspection device and liquid inspection method
JP6281534B2 (en) * 2015-07-22 2018-02-21 栗田工業株式会社 Aggregation monitoring apparatus, aggregation monitoring method, and aggregation system
TWI773721B (en) * 2017-01-20 2022-08-11 日商東京威力科創股份有限公司 Foreign body detection device, foreign body detection method, and memory medium
JP2020509357A (en) * 2017-02-10 2020-03-26 アムジエン・インコーポレーテツド Imaging system for counting and sizing particles in a fluid-filled container
US10088660B2 (en) 2017-02-10 2018-10-02 Amgen Inc. Imaging system for counting and sizing particles in fluid-filled vessels
CN107088446A (en) * 2017-06-23 2017-08-25 亿信标准认证集团四川有限公司 The rack for test tube for being easy to check using indicator lamp
WO2020072845A1 (en) * 2018-10-05 2020-04-09 University Of Baltimore Systems, methods and apparatus for utilizing a resuspension tank
JP7322593B2 (en) * 2019-08-23 2023-08-08 株式会社サタケ Microorganism inspection device and method
EP4113101B1 (en) * 2021-06-28 2023-08-09 Metavital GmbH Device performing a radiation measurement of a biological sample in a receptacle-device

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6166151A (en) * 1984-09-08 1986-04-04 Olympus Optical Co Ltd Automatic immunoreaction measuring apparatus
US20060120566A1 (en) * 2003-04-24 2006-06-08 Toru Myogadani Optical inspection device

Family Cites Families (97)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3013466A (en) 1957-07-18 1961-12-19 Baird Atomic Inc Turbidity measuring instrument
GB1013874A (en) 1963-07-03 1965-12-22 Nat Res Dev Improvements in apparatus for determining the turbidity of fluids
GB1122809A (en) 1964-11-04 1968-08-07 Ici Ltd Device for measuring turbidity in fluids
GB1128446A (en) 1964-11-26 1968-09-25 Nat Res Dev Measurement of turbidity of fluids
US3522436A (en) 1969-02-17 1970-08-04 Edward Salmon Posgate Turbidimeters
US3713743A (en) 1970-11-25 1973-01-30 Agricultural Control Syst Forward scatter optical turbidimeter apparatus
US3744665A (en) 1971-06-14 1973-07-10 V Spoto Combination vial and test tube rack
US3775013A (en) 1971-11-17 1973-11-27 Monitor Techn Inc Optical turbidimeter apparatus
US3832532A (en) 1972-08-18 1974-08-27 Pfizer Method and apparatus for testing antibiotic susceptibility
US3826574A (en) 1973-02-12 1974-07-30 Continental Distributors Nephelometer
GB1486210A (en) 1973-11-14 1977-09-21 Suovaniemi Osmo Antero Cuvette assembly for use in automatic reading and recording of reaction results
US4363551A (en) 1976-06-01 1982-12-14 Baxter Travenol Laboratories, Inc. Nephelometer having means semiautomatically canceling components from scattering by particles smaller or larger than those of interest
US4152070A (en) 1977-02-04 1979-05-01 Envirotech Corporation Turbidimeter
US4169125A (en) 1977-04-14 1979-09-25 Baxter Travenol Laboratories, Inc. Modular chemical analysis system
US4448534A (en) 1978-03-30 1984-05-15 American Hospital Corporation Antibiotic susceptibility testing
JPS5925460B2 (en) 1978-05-19 1984-06-18 株式会社日立製作所 Nephelometric immunoassay method and device
JPS5516258A (en) 1978-07-20 1980-02-04 Hitachi Ltd Optical system of nephelometer
US4343552A (en) 1979-12-28 1982-08-10 Purecycle Corporation Nephelometer
DE3026089A1 (en) 1980-07-10 1982-06-09 Hans Günter Priv.Doz. Dr.med. 6900 Heidelberg Nöller FLASH PHOTOMETER FOR NEPHELOMETRIC AND FLUOROMETRIC APPLICATIONS
US4477190A (en) 1981-07-20 1984-10-16 American Hospital Supply Corporation Multichannel spectrophotometer
JPS5899733A (en) 1981-12-08 1983-06-14 Mitsubishi Electric Corp Turbidimeter
JPS59100862A (en) 1982-12-01 1984-06-11 Hitachi Ltd Automatic analyzer
FI831936A0 (en) 1983-05-30 1983-05-30 Labsystems Oy FLUORESCENS, TURBIDITY, LUMINESCENS ELLER ABSORPTION
JPS60125541A (en) 1983-12-13 1985-07-04 Olympus Optical Co Ltd Turbidity detection of liquid to be examined
US5202262A (en) 1984-01-31 1993-04-13 Millipore Corporation Apparatus for microbiological testing of liquids
US4669878A (en) 1984-06-29 1987-06-02 American Monitor Corporation Automatic monochromator-testing system
US4603977A (en) 1984-10-31 1986-08-05 Research Corporation Micromotility meter
US4687336A (en) 1985-03-05 1987-08-18 Abbott Laboratories Measurement of optical density via nephenometry
FI90592C (en) 1989-02-16 1994-02-25 Anadis Instr Sa IR spectrometric analysis method and IR spectrometer
US5011286A (en) * 1989-08-03 1991-04-30 Met One, Inc. Multisensor particle counter utilizing a single energy source
CA2025330C (en) 1989-09-18 2002-01-22 David W. Osten Characterizing biological matter in a dynamic condition using near infrared spectroscopy
JPH03189542A (en) 1989-12-19 1991-08-19 Kyoto Denshi Kogyo Kk Colorimetric analysis apparatus and analysis method
DE4030699C1 (en) 1990-09-28 1991-10-10 Bruker Analytische Messtechnik Gmbh, 7512 Rheinstetten, De
US5116122A (en) 1991-03-14 1992-05-26 Shimadzu Corporation Spectrophotometer
JPH0518885A (en) 1991-07-12 1993-01-26 Toshiba Corp Method and device for measuring turbidity of liquid and measurement device
JPH0650889A (en) 1992-07-31 1994-02-25 Shimadzu Corp Near-infrared analytical apparatus
US6235531B1 (en) 1993-09-01 2001-05-22 Abaxis, Inc. Modified siphons for improved metering precision
JPH07253392A (en) 1994-03-15 1995-10-03 Kubota Corp Measuring cell for turbidity sensor
US5589935A (en) * 1995-05-25 1996-12-31 Honeywell, Inc. Turbidity sensor with the capability of regulating the intensity of a light source
US6709869B2 (en) 1995-12-18 2004-03-23 Tecan Trading Ag Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system
US5940178A (en) 1996-07-03 1999-08-17 Beckman Instruments, Inc. Nephelometer and turbidimeter combination
GB9618923D0 (en) 1996-09-11 1996-10-23 Holley John E F Scanning device
RU2132635C1 (en) 1996-09-30 1999-07-10 Алексеев Сергей Григорьевич Method and device for diagnosing oncological diseases
US5872361A (en) 1997-03-24 1999-02-16 Hach Company Turbidimeter with non-imaging optical concentrator
JPH10332582A (en) 1997-05-28 1998-12-18 Kyowa Medex Co Ltd Measuring apparatus for turbidity
DE69940647D1 (en) 1998-05-01 2009-05-07 Gen Probe Inc Automatic diagnostic analyzer
US6331437B1 (en) 1998-07-14 2001-12-18 Bayer Corporation Automatic handler for feeding containers into and out of an analytical instrument
US5963318A (en) 1998-08-07 1999-10-05 Bio-Tek Holdings, Inc. Method of and apparatus for performing fixed pathlength vertical photometry
US7649153B2 (en) 1998-12-11 2010-01-19 International Business Machines Corporation Method for minimizing sample damage during the ablation of material using a focused ultrashort pulsed laser beam
US20020186363A1 (en) 1999-09-03 2002-12-12 James Samsoondar Method and apparatus for screening plasma for interferents in plasma from donor blood bags
WO2001029534A1 (en) 1999-10-15 2001-04-26 The Administrators Of The Tulane Educational Fund Device for and method of simultaneously measuring light scatter from multiple liquid samples
GB9924537D0 (en) 1999-10-18 1999-12-15 Siemens Plc Device for measuring water quality
US6307630B1 (en) 1999-11-19 2001-10-23 Hach Company Turbidimeter array system
DE10008517C2 (en) 2000-02-24 2002-09-26 Eppendorf Ag Optical measuring system
US6620585B1 (en) 2000-08-02 2003-09-16 Elitra Pharmaceuticals, Inc. Use of ectoenzymes and secreted enzymes to monitor cellular proliferation
US20020086431A1 (en) 2000-08-21 2002-07-04 Markham Walter Bruce Sample preparation and slide plating apparatus and method
CA2423552A1 (en) 2000-10-13 2002-04-18 Irm Llc High throughput processing system and method of using
GB2369182B (en) 2000-11-15 2004-12-08 Rusteck Ltd Optical detection of particles in a liquid medium
US20030069699A1 (en) 2001-05-16 2003-04-10 Sean Ekins Device for drug-drug interaction testing sample preparation
KR20040018378A (en) 2001-05-23 2004-03-03 하크 컴퍼니 Optical turbidimeter with a lens tube
JP4420168B2 (en) * 2001-08-30 2010-02-24 味の素株式会社 Turbidity sensor
EP1314972B1 (en) 2001-11-26 2010-07-14 X-Rite Europe GmbH Spectrophotometer and its use
AU2002357178A1 (en) 2001-12-14 2003-06-30 Cygene, Inc. Diagnostic assays for bcwa
US7033542B2 (en) 2002-02-14 2006-04-25 Archibald William B High throughput screening with parallel vibrational spectroscopy
US6894778B2 (en) 2002-04-23 2005-05-17 Hach Company Low detection limit turbidimeter
DK1388734T3 (en) * 2002-08-01 2004-05-03 Mtm Lab Ag Method for solution-based diagnosis
AU2003264805A1 (en) 2002-10-18 2004-05-04 Brian David Bissett Automated kinetci solubility assay apparatus and method
US7000785B2 (en) 2003-04-03 2006-02-21 Bio-Rad Laboratories, Inc. Tube rack accommodating a range of tube diameters
FI20030867A (en) 2003-06-10 2004-12-11 Wallac Oy Optical measuring method and laboratory measuring apparatus
US20040260157A1 (en) 2003-06-20 2004-12-23 Montes Miguel A. Method for automated screening of cervical/endocervical malignant and premalignant epithelial lesions using flow cytometry with HPV DNA fluorescent in-situ hybridization ( FISH) technology
DE602004003632T2 (en) 2003-07-09 2007-10-25 Matsushita Electric Industrial Co., Ltd., Kadoma Turbidimetric immunoassay method and associated apparatus
US7803624B2 (en) 2003-09-30 2010-09-28 Cytyc Corporation Automated cytological sample classification
US7339671B2 (en) 2004-01-20 2008-03-04 Hong Peng Apparatus and method for monitoring biological cell culture
JP2006047166A (en) 2004-08-06 2006-02-16 Yokogawa Electric Corp Turbidimeter
US8951746B2 (en) 2004-11-05 2015-02-10 Southwest Research Institute Method and devices for screening cervical cancer
US7142299B2 (en) 2004-11-18 2006-11-28 Apprise Technologies, Inc. Turbidity sensor
US7610115B2 (en) 2004-12-22 2009-10-27 Intelligent Hospital Systems Ltd. Automated pharmacy admixture system (APAS)
US7491366B2 (en) 2005-03-03 2009-02-17 Ecolab Inc. Portable multi-channel device for optically testing a liquid sample
AU2005331515A1 (en) 2005-05-05 2006-11-09 Ron Emburgh System for rapid analysis of microbiological materials in liquid samples
JP2006317270A (en) 2005-05-12 2006-11-24 Yokogawa Electric Corp Turbidity meter
JP4487197B2 (en) 2005-05-12 2010-06-23 横河電機株式会社 Turbidity / colorimeter
US7339668B2 (en) 2005-10-18 2008-03-04 Thermo Electron Scientific Instruments Llc Spectrometer for analysis of multiple samples
WO2007048042A2 (en) 2005-10-21 2007-04-26 University Of Alabama At Birmingham Small molecule inhibitors of hiv-1 capsid assembly
WO2007060583A2 (en) 2005-11-28 2007-05-31 Koninklijke Philips Electronics N.V. Method and apparatus for determining concentrations of analytes in a turbid medium
GB2431232B (en) 2005-12-14 2007-10-10 Zinir Ltd Spectrophotometer
US7550746B2 (en) 2006-06-01 2009-06-23 Ecolab Inc. UV fluorometric sensor and method for using the same
US7842499B2 (en) 2006-08-07 2010-11-30 Platypus Technologies, Llc Substrates, devices, and methods for cellular assays
JP2008064594A (en) 2006-09-07 2008-03-21 Yokogawa Electric Corp Turbidimeter
KR100817854B1 (en) 2006-09-19 2008-03-31 재단법인서울대학교산학협력재단 A simultaneous detection apparatus of Raman and Light Scattering
US20080174768A1 (en) 2007-01-18 2008-07-24 Mathias Belz Self referencing LED detection system for spectroscopy applications
JP2008249363A (en) 2007-03-29 2008-10-16 Dkk Toa Corp Turbidimeter
US7985375B2 (en) 2007-04-06 2011-07-26 Qiagen Gaithersburg, Inc. Sample preparation system and method for processing clinical specimens
JP4905798B2 (en) 2007-05-18 2012-03-28 横河電機株式会社 Turbidity meter
US7430043B1 (en) 2007-06-07 2008-09-30 Evans James M Turbidimeter improvements
GB0710957D0 (en) * 2007-06-07 2007-07-18 Norchip As A device for carrying out cell lysis and nucleic acid extraction
US9696261B2 (en) 2007-10-12 2017-07-04 Ecolab Usa Inc. Multi-channel device and method for measuring optical properties of a liquid
US8582106B2 (en) 2007-11-09 2013-11-12 Hach Company Automatic optical measurement system and method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6166151A (en) * 1984-09-08 1986-04-04 Olympus Optical Co Ltd Automatic immunoreaction measuring apparatus
US20060120566A1 (en) * 2003-04-24 2006-06-08 Toru Myogadani Optical inspection device

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2010141040A1 *

Also Published As

Publication number Publication date
CA2764237C (en) 2018-09-11
EP2438438B1 (en) 2019-07-10
AU2009347207B2 (en) 2014-07-31
JP2012529048A (en) 2012-11-15
TW201105948A (en) 2011-02-16
EP2438438A1 (en) 2012-04-11
TWI486570B (en) 2015-06-01
US20100205139A1 (en) 2010-08-12
ES2737403T3 (en) 2020-01-14
AU2009347207A1 (en) 2012-01-12
JP5542922B2 (en) 2014-07-09
WO2010141040A1 (en) 2010-12-09
CA2764237A1 (en) 2010-12-09
US8877507B2 (en) 2014-11-04

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