EP2402439A4 - Procédé d'immunisation utilisant une cellule cancéreuse - Google Patents

Procédé d'immunisation utilisant une cellule cancéreuse

Info

Publication number
EP2402439A4
EP2402439A4 EP10746350.7A EP10746350A EP2402439A4 EP 2402439 A4 EP2402439 A4 EP 2402439A4 EP 10746350 A EP10746350 A EP 10746350A EP 2402439 A4 EP2402439 A4 EP 2402439A4
Authority
EP
European Patent Office
Prior art keywords
cancer cell
immunization method
immunization
cancer
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP10746350.7A
Other languages
German (de)
English (en)
Other versions
EP2402439A1 (fr
EP2402439B1 (fr
Inventor
Hiroyuki Satofuka
Masahiro Uchino
Hiroko Kojima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ORDER-MADE MEDICAL RESEARCH Inc
Original Assignee
Ordermade Medical Res Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ordermade Medical Res Inc filed Critical Ordermade Medical Res Inc
Publication of EP2402439A1 publication Critical patent/EP2402439A1/fr
Publication of EP2402439A4 publication Critical patent/EP2402439A4/fr
Application granted granted Critical
Publication of EP2402439B1 publication Critical patent/EP2402439B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5152—Tumor cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5156—Animal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
EP10746350.7A 2009-02-27 2010-02-26 Procédé de préparation d'un hybridome par la transplantation de cellules de cancer du sein Active EP2402439B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2009046730 2009-02-27
PCT/JP2010/053168 WO2010098471A1 (fr) 2009-02-27 2010-02-26 Procédé d'immunisation utilisant une cellule cancéreuse

Publications (3)

Publication Number Publication Date
EP2402439A1 EP2402439A1 (fr) 2012-01-04
EP2402439A4 true EP2402439A4 (fr) 2013-11-27
EP2402439B1 EP2402439B1 (fr) 2018-12-12

Family

ID=42665675

Family Applications (1)

Application Number Title Priority Date Filing Date
EP10746350.7A Active EP2402439B1 (fr) 2009-02-27 2010-02-26 Procédé de préparation d'un hybridome par la transplantation de cellules de cancer du sein

Country Status (4)

Country Link
US (1) US20110318387A1 (fr)
EP (1) EP2402439B1 (fr)
JP (1) JP5688699B2 (fr)
WO (1) WO2010098471A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012026615A1 (fr) * 2010-08-25 2012-03-01 株式会社バイオマトリックス研究所 Procédé de production d'anticorps à l'aide de cellules cancéreuses
AU2012255143A1 (en) * 2011-05-19 2014-02-20 The Regents Of The University Of Michigan Integrin alpha-2 binding agents and use thereof to inhibit cancer cell proliferation
US20150174224A1 (en) * 2011-05-19 2015-06-25 The Regents Of The University Of Michigan Materials and Methods for Eliciting Targeted Antibody Responses In Vivo
WO2013133450A1 (fr) 2012-03-06 2013-09-12 株式会社バイオマトリックス研究所 Composition pharmaceutique pour traiter le cancer
WO2015108203A1 (fr) 2014-01-15 2015-07-23 株式会社オーダーメードメディカルリサーチ Composition pharmaceutique thérapeutique utilisant un anticorps anti-slc6a6
JP2017100947A (ja) * 2014-03-31 2017-06-08 株式会社オーダーメードメディカルリサーチ 目的抗原に対する抗体の作製方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0280209A2 (fr) * 1987-02-20 1988-08-31 The Wistar Institute Anticorps monoclonaux contre des antigènes associés au mélanome, lignées cellulaires hybrides produisant ces anticorps et leur utilisation
WO2004056847A2 (fr) * 2002-12-16 2004-07-08 Genmab A/S Anticorps monoclonaux humains contre le recepteur de facteur de croissance epidermique (egfr)
US20040141913A1 (en) * 2003-01-21 2004-07-22 Young David S. F. Cancerous disease modifying antibodies

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6429400A (en) * 1987-07-24 1989-01-31 Akio Hirohashi Monoclonal antibody
EP0752248B1 (fr) 1992-11-13 2000-09-27 Idec Pharmaceuticals Corporation Application thérapeutique d'anticorps chimériques et radio-marqués contre l'antigène à differentiation restreinte des lymphocytes B humains pour le traitement du lymphome des cellules B
JP3447322B2 (ja) 1993-05-26 2003-09-16 財団法人大阪バイオサイエンス研究所 マウス細胞表面抗原に対するハムスターモノクローナル抗体
JPH07188056A (ja) 1993-07-21 1995-07-25 Chuzo Kishimoto インターロイキン６リセプター抗体を有効成分とする骨吸収抑制剤
JPH07313187A (ja) 1994-05-24 1995-12-05 Sagami Chem Res Center 抗体作製法
US5986170A (en) * 1995-11-13 1999-11-16 Corixa Corporation Murine model for human carcinoma
AU2447999A (en) 1997-09-26 1999-05-03 Corixa Corporation Murine model for human carcinoma
AU2002246668A1 (en) 2000-11-02 2002-07-30 Molecular Discoveries, L.L.C. Monoclonal antibodies and cell surface antigens for the detection and treatment of small cell lung cancer (sclc)
JP5314242B2 (ja) * 2004-04-27 2013-10-16 中外製薬株式会社 プラズマ細胞の増殖方法
EP2096166A1 (fr) 2005-03-31 2009-09-02 Osaka University Procédé de production d'anticorps dirigé contre l'épitope antig?ne de surface de membrane cellulaire et procédé d'analyse
WO2008093886A1 (fr) 2007-01-30 2008-08-07 Bio Matrix Research, Inc. Cellule dérivée de mcf7
JP4912980B2 (ja) 2007-08-20 2012-04-11 株式会社アルバック 成膜方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0280209A2 (fr) * 1987-02-20 1988-08-31 The Wistar Institute Anticorps monoclonaux contre des antigènes associés au mélanome, lignées cellulaires hybrides produisant ces anticorps et leur utilisation
WO2004056847A2 (fr) * 2002-12-16 2004-07-08 Genmab A/S Anticorps monoclonaux humains contre le recepteur de facteur de croissance epidermique (egfr)
US20040141913A1 (en) * 2003-01-21 2004-07-22 Young David S. F. Cancerous disease modifying antibodies

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
KITAMURA ET AL: "Specificity analysis of blood group Lewis-y (Le(y)) antibodies generatedagainst synthetic and natural Le(y) determinants.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, vol. 91, no. 26, 1 December 1994 (1994-12-01), pages 12957 - 12961, XP055057081, ISSN: 0027-8424 *
OHNO YOSHIYA ET AL: "Production and characterization of highly tumor-specific rat monoclonal antibodies recognizing the extracellular domain of human l-type amino-acid transporter 1", CANCER SCIENCE, JAPANESE CANCER ASSOCIATION, TOKYO, JP, vol. 99, no. 5, 1 May 2008 (2008-05-01), pages 1000 - 1007, XP002476425, ISSN: 1347-9032, DOI: 10.1111/J.1349-7006.2008.00770.X *
See also references of WO2010098471A1 *
STARLING J J ET AL: "MONO CLONAL ANTIBODIES TO HUMAN PROSTATE AND BLADDER TUMOR ASSOCIATED ANTIGENS", CANCER RESEARCH, vol. 42, no. 8, 1982, pages 3084 - 3089, XP009173416, ISSN: 0008-5472 *
TOYA NATH BARAL ET AL: "Isolation of functional single domain antibody by whole cell immunization: Implications for cancer treatment", JOURNAL OF IMMUNOLOGICAL METHODS, ELSEVIER SCIENCE PUBLISHERS B.V.,AMSTERDAM, NL, vol. 371, no. 1, 16 June 2011 (2011-06-16), pages 70 - 80, XP028254103, ISSN: 0022-1759, [retrieved on 20110630], DOI: 10.1016/J.JIM.2011.06.017 *

Also Published As

Publication number Publication date
EP2402439A1 (fr) 2012-01-04
JP5688699B2 (ja) 2015-03-25
EP2402439B1 (fr) 2018-12-12
US20110318387A1 (en) 2011-12-29
WO2010098471A1 (fr) 2010-09-02
JPWO2010098471A1 (ja) 2012-09-06

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