Classifications

• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
  • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
  • A61K8/37—Esters of carboxylic acids
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
  • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K31/00—Medicinal preparations containing organic active ingredients
  • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
  • A61K8/0216—Solid or semisolid forms
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
  • A61P17/00—Drugs for dermatological disorders
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
  • A61Q19/00—Preparations for care of the skin
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
  • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
  • A61Q1/02—Preparations containing skin colorants, e.g. pigments
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
  • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
  • A61Q1/02—Preparations containing skin colorants, e.g. pigments
  • A61Q1/04—Preparations containing skin colorants, e.g. pigments for lips
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
  • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
  • A61Q1/02—Preparations containing skin colorants, e.g. pigments
  • A61Q1/04—Preparations containing skin colorants, e.g. pigments for lips
  • A61Q1/06—Lipsticks
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
  • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
  • A61Q1/02—Preparations containing skin colorants, e.g. pigments
  • A61Q1/10—Preparations containing skin colorants, e.g. pigments for eyes, e.g. eyeliner, mascara
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
  • A61Q15/00—Anti-perspirants or body deodorants
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
  • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
  • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
  • A61Q19/00—Preparations for care of the skin
  • A61Q19/08—Anti-ageing preparations
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
  • A61Q5/00—Preparations for care of the hair
  • A61Q5/06—Preparations for styling the hair, e.g. by temporary shaping or colouring
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
  • A61Q5/00—Preparations for care of the hair
  • A61Q5/12—Preparations containing hair conditioners

Definitions

• the present invention relates to cosmetic and / or pharmaceutical preparations containing from 0.1 to 80% by weight of n-octyl n-octanoate.
• esters should be compatible in particular with crystalline UV filters, pigments, antiperspirant salts and silicones
• the esters should be resistant to oxidation
• decorative cosmetics for example, make-up
• esters compatibility of the esters with preparations containing detergent substances (such as shower baths, shampoos, hair conditioners) is of interest. It has also been of particular interest to provide substances that can completely or partially replace silicone oil in cosmetic and / or pharmaceutical preparations.
• the silicone oils used in the prior art are disadvantageous, inter alia, because of their bioaccumulation.
• Of particular interest was also to provide substances that have a low Irriationspotential (ua Skin and eyes).
• WO 2006/097235 describes esters of 2-propylheptanol with linear or branched carboxylic acids. The object of the present invention was to provide improved over the prior art esters. It has been found that the esters of the present invention accomplish this task.
• the cosmetic and / or pharmaceutical preparations according to the invention are light and stable cosmetic and / or pharmaceutical preparations.
• An object of the invention relates to cosmetic and / or pharmaceutical preparations containing n-octyl-n-octanoate.
• a preferred subject of the invention relates to cosmetic and / or pharmaceutical preparations containing 0.1 to 80 wt .-% of n-octyl-n-octanoate.
• n-Octyl-n-octanoate is the ester of n-octanol with n-octanoic acid and follows the formula:
• n-octyl-n-octanoate i. the ester of n-octanol and n-octanoic acid is known as a substance (CAS No. 2306-88-9), e.g. as a pheromone in the animal kingdom. The cosmetic use of this substance is not described in the prior art.
• n-Octyl-n-octanoate can be prepared by methods known to those skilled in the art, e.g. Esterification of alcohol and acid or transesterification of alcohol and methyl ester.
• the cosmetic and / or pharmaceutical preparations according to the invention are light and stable cosmetic and / or pharmaceutical preparations, this is especially the case if they also contain antiperspirant / deodorant active ingredients.
• An object of the invention therefore relates to cosmetic and / or pharmaceutical preparations containing n-octyl-n-octanoate and at least one antiperspirant / deodorant active ingredient.
• An object of the invention therefore relates to cosmetic and / or pharmaceutical preparations containing 0.1 to 80 wt .-% n-octyl-n-octanoate and at least one antiperspirant / deodorant active ingredient.
• Suitable antiperspirant / deodorant active compounds are in particular compounds selected from the group consisting of antiperspirants, esterase inhibitors, bactericidal or bacteriostatic agents and / or sweat-absorbing substances.
• Antiperspirants are salts of aluminum, zirconium or zinc.
• suitable antiperspirant active ingredients are e.g. Aluminum chloride, aluminum chlorohydrate, aluminum dichlorohydrate, aluminum sesquichlorohydrate and their complex compounds e.g. With propylene glycol-1, 2. Aluminiumhydroxyallantoinat, aluminum chloride tartrate, aluminum zirconium trichlorohydrate, aluminum zirconium tetrachlorohydrate, aluminum zirconium pentachlorohydrate and their complex compounds z. With amino acids such as glycine.
• aluminum chlorohydrate, aluminum zirconium tetrachlorohydrate, aluminum zirconium pentachlorohydrate and their complex compounds are used.
• the preparations according to the invention may contain the antiperspirants in amounts of from 1 to 50, preferably from 5 to 30, and in particular from 8 to 25,% by weight, based on the total weight of the cosmetic and / or pharmaceutical preparation.
• esterase inhibitors are preferably trialkyl citrates such as trimethyl citrate, tripropyl citrate, triisopropyl citrate, tributyl citrate and in particular triethyl citrate (Hydagen® CAT, Cognis GmbH, Dusseldorf / FRG).
• the substances inhibit the enzyme activity and thereby reduce odors.
• esterase inhibitors are sterol sulfates or phosphates, such as, for example, lanosterol, cholesterol, campesterrin, stigmasterol and sitosterol sulfate or phosphate, dicarboxylic acids and their esters, for example glutaric acid, glutaric acid monoethyl ester, glutaric acid diethyl ester, Adipic acid, adiponylsulfonate, diethyl adipate, malonic acid and diethyl malonate, hydroxycarboxylic acids and their esters, for example citric acid, malic acid, tartaric acid or diethyl tartaric acid, and zinc glycinate.
• the preparations according to the invention may contain the esterase inhibitors in amounts of from 0.01 to 20, preferably from 0.1 to 10, and in particular from 0.3 to 5,% by weight, based on the total weight of the cosmetic and / or pharmaceutical preparation.
• bactericidal or bacteriostatic agents are in particular chitosan and phenoxyethanol.
• 5-Chloro-2- (2,4-dichlorophenoxy) phenol which is marketed under the trade name Irgasan® by Ciba-Geigy, Basel / CH, has also proved to be particularly effective.
• germ-inhibiting agents are basically all effective against Gram-positive bacteria substances such.
• the preparations according to the invention may contain the bactericidal or bacteriostatic agents in amounts of from 0.01 to 5 and preferably from 0.1 to 2% by weight, based on the total weight of the cosmetic and / or pharmaceutical preparation.
• modified starch such as e.g. Dry FIo Plus (National Starch).
• the preparations according to the invention can be the sweat-absorbing
• the cosmetic and / or pharmaceutical preparations according to the invention are light and stable cosmetic and / or pharmaceutical preparations, this is especially the case if they further contain at least one UV light protection filter.
• An object of the invention therefore relates to cosmetic and / or pharmaceutical preparations containing n-octyl-n-octanoate and at least at least one UV light protection filter.
• An object of the invention preferably relates to cosmetic and / or pharmaceutical preparations containing 0.1 to 80 wt .-% of n-octyl n-octanoate and at least one UV photoprotective filter.
• liquid or crystalline organic substances which are capable of absorbing ultraviolet rays and absorb the absorbed energy in the form of longer-wave radiation, e.g. Heat again.
• UV filters can be oil-soluble or water-soluble.
• 4-aminobenzoic acid derivatives preferably 2-ethylhexyl 4- (dimethylamino) benzoate, 2-octyl 4- (dimethylamino) benzoate and 4- (dimethylamino) benzoic acid amyl ester;
• esters of cinnamic acid preferably 4-methoxycinnamic acid 2-ethylhexyl ester, propyl 4-methoxycinnamate, isoamyl 4-methoxycinnamate, 2-ethylhexyl 2-cyano-3,3-phenylcinnamate (octocrylenes);
• Esters of salicylic acid preferably 2-ethylhexyl salicylate, 4-isopropylisopropyl salicylate, homomenthyl salicylate;
• benzophenone preferably 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxy-4'-methylbenzophenone, 2,2'-dihydroxy-4-methoxybenzophenone;
• Esters of benzalmalonic acid preferably di-2-ethylhexyl 4-methoxybenzmalonate
• Triazine derivatives such as 2,4,6-trianilino (p-carbo-2'-ethyl-1'-hexyloxy) -1, 3,5-triazine and 2,4,6-tris [p- (2-triazine) ethylhexyl-oxycarbonyl) anilino] -1,3,5-triazine (Uvinul T 150) as described in EP 0818450 A1 or 4,4 ' - [(6- [4- (1, 1-dimethylethyl) amino] -carbonyl) phenylamino] -1, 3,5-triazine-2,4-diyl) diimino] bis (benzoic acid 2-ethylhexyl ester) (Uvasorb® HEB);
• Suitable water-soluble UV filters are:
• Sulphonic acid derivatives of benzophenones preferably 2-hydroxy-4-methoxybenzo-phenone-5-sulphonic acid and their salts;
• Sulfonic acid derivatives of the 3-benzylidene camphor e.g. 4- (2-Oxo-3-bomylidenemethyl) benzenesulfonic acid and 2-methyl-5- (2-oxo-3-bomylidene) -sulfonic acid and its salts.
• UV-A filter in particular derivatives of benzoylmethane are suitable, such as 1- (4'-tert-butylphenyl) -3- (4'-methoxyphenyl) propane-1,3-dione, 4-tert-butyl 4'-methoxydibenzoylmethane (Parsol® 1789), 1-phenyl-3- (4'-isopropylphenyl) -propane-1, 3-dione and also enamine compounds as described in DE 19712033 A1 (BASF) and benzoic acid, 2- [4- (diethylamino) -2-hydroxybenzoyl], hexyl ester (Uvinul® A plus).
• benzoylmethane such as 1- (4'-tert-butylphenyl) -3- (4'-methoxyphenyl) propane-1,3-dione, 4-tert-butyl 4'-methoxydibenzoylmethane (Parsol® 1789), 1-phen
• UV-A and UV-B filters can also be used in mixtures.
• Particularly favorable combinations consist of the derivatives of benzoylmethane, e.g. 4-tert-butyl-4'-methoxydibenzoylmethane (Parsol® 1789) and 2-cyano-3,3-phenylcinnamic acid 2-ethylhexyl ester (octocrylene) in combination with esters of cinnamic acid, preferably 4-methoxycinnamic acid 2-ethylhexyl ester and / or 4-Methoxycinntklarepropylester and / or 4-Methoxycinntklareisoamylester.
• benzoylmethane e.g. 4-tert-butyl-4'-methoxydibenzoylmethane (Parsol® 1789) and 2-cyano-3,3-phenylcinnamic acid 2-ethylhexyl ester (
• water-soluble filters e.g. 2-phenylbenzimidazole-5-sulfonic acid and their alkali, alkaline earth, ammonium, alkylammonium, alkanolammonium and glucammonium combined.
• UV light protection filters are those according to Annex VII of the Commission Directive (in the version of Commission Directive 2005/9 / EC of 28 January 2005 amending Council Directive 76/768 / EEC, concerning cosmetic purposes, for the purposes of adapting Annexes VII thereof to technical progress) substances, which are explicitly referred to here.
• insoluble photoprotective pigments namely finely dispersed metal oxides or salts
• suitable metal oxides are, in particular, zinc oxide and titanium dioxide and, in addition, oxides of iron, zirconium, Siliciums, manganese, aluminum and cerium and their mixtures.
• silicates (talc) barium sulfate or zinc stearate can be used.
• the oxides and salts are used in the form of the pigments for skin-care and skin-protecting emulsions and also for decorative cosmetics.
• the particles should have an average diameter of less than 100 nm, preferably between 5 and 50 nm and in particular between 15 and 30 nm.
• the pigments may have a spherical shape, but it is also possible to use those particles which have an ellipsoidal or otherwise deviating shape from the spherical shape.
• the pigments may also be surface-treated, ie hydrophilized or hydrophobicized.
• Typical examples are coated titanium dioxides, such as titanium dioxide T 805 (Degussa) or Eusolex® T, Eusolex® T-2000, Eusolex® T-Aqua, Eusolex® AVO, Eusolex® T-ECO, Eusolex® T-OLEO and Eusolex® TS (Merck).
• Typical examples are zinc oxides such as Zinc Oxide neutral, Zinc Oxide NDM (Symrise) or Z-Cote® (BASF) or SUNZnO-AS and SUNZnO-NAS (Sunjun Chemical Co. Ltd.).
• Suitable hydrophobic coating agents are in particular silicones and in particular trialkoxyoctylsilanes or simethicones.
• sunscreens so-called micro- or nanopigments are preferably used.
• micronized zinc oxide is used.
• Further suitable UV photoprotective filters are the review by P.Finkel in S ⁇ FW Journal 122, 8/1996, pp 543-548 and Parf.Kosm. Volume 80, No. 3/1999, pp. 10 to 16.
• secondary light stabilizers of the antioxidant type which interrupt the photochemical reaction chain which is triggered when UV radiation penetrates into the skin.
• Typical examples are amino acids (eg glycine, histidine, tyrosine, tryptophan) and their derivatives, imidazoles (eg urocaninic acid) and their derivatives, peptides such as DL-carnosine, D-carnosine, L-carnosine and their derivatives (eg anserine), carotenoids , Carotenes (eg carotene, carotene, lycopene) and their derivatives, chlorogenic acid and its derivatives, lipoic acid and its derivatives (eg dihydrolipoic acid), aurothioglucose, propylthiouracil and other thiols (eg thioredoxin, glutathione, cysteine, cystine, cysteine) min and their glycos
• amino acids eg glycine, histidine, ty
• An object of the invention therefore relates to cosmetic and / or pharmaceutical preparations containing n-octyl n-octanoate and at least one UV light protection filter selected from the group consisting of 4-methylbenzylidene camphor, benzophenone-3, butyl methoxydibenzoylmethane, bis-Ethylhexyloxyphenol methoxyphenyl Triazines, methylene bis -benzotriazolyl tetramethylbutylphenol, diethylhexylbutamido triazone, ethylhexyl triazone and diethylamino hydroxybenzoyl hexyl benzoate, 3- (4'-trimethylammonium) benzylidene boman-2-one methylsulfate, 3,3 '- (1,4-phenylenedimethine) bis (7,7-dimethyl-2-oxobicyclo [2.2.1] heptane-1-methanesul
• An object of the invention therefore relates to cosmetic and / or pharmaceutical preparations containing from 0.1 to 80% by weight of n-octyl n-octanoate and at least one UV light protection filter selected from the group consisting of 4-methylbenzylidene camphor, benzophenone-3 , Butyl methoxydibenzoylmethane, bis-ethylhexyloxyphenol methoxyphenyl triazines, methylene bis-benzotriazolyl tetramethylbutylphenol, diethylhexyl butamido triazone, ethylhexyl triazone and diethylamino hydroxybenzoyl hexyl benzoate, 3- (4'-trimethylammonium) benzylidenebornan-2-one methylsulfate, 3,3 ' - (1,4-phenylenedimethine) -bis (7,7-dimethyl-2-oxobicyclo [2.2.1]
• UV photoprotective filters are commercially available, for example, under the following trade names: NeoHeliopan®MBC (INCI: 4-methylbenzylidene camphor, manufacturer: Symrise); NeoHeliopan® BB (INCI: Benzophenone-3, manufacturer: Symrise); Parsol® 1789 (INCI: Butyl methoxydibenzoylmethane, manufacturer: Hoffmann-La Roche (Givaudan); Tinosorb® S (INCI: bis-ethylhexyloxyphenol methoxyphenyl triazines); Tinosorb TM (INCI: methylene bis-benzotriazolyl tetramethylbutylphenol): manufacturer: Ciba Specialty Chemicals Corporation; Uvasorb® HEB ( INCI: diethylhexyl butamido triazone, manufacturer: 3V Inc.), Uvinul®T 150 (INCI: ethylhexyl triazone, manufacturer: BASF AG), Uvinul® A
• the preparations according to the invention may contain the UV light protection filters in amounts of 0.5 to 30% by weight, preferably 2.5 to 20% by weight, particularly preferably 5 to 15% by weight, based on the total weight of the cosmetic and / or or pharmaceutical preparation.
• An object of the invention relates to cosmetic and / or pharmaceutical preparations containing n-octyl-n-octanoate and at least at least one self-tanner.
• a preferred subject of the invention relates to cosmetic and / or pharmaceutical preparations containing 0.1 to 80 wt .-% of n-octyl n-octanoate and at least one self-tanner.
• Suitable active ingredients for self-tanning agents are natural or synthetic ketols or aldols. Examples of suitable active compounds are dihydroxyacetone, erythrulose, glycerol aldehyde, alloxan, hydroxymethylglyoxal, gamma-dialdehyde, 6-aldo-D-fructose, ninhydrin and meso-tartaric dialdehyde.
• Suitable self-tanning agents are, in particular, dihydroxyacetone and / or erythrulose. Be particularly advantageous mixtures of the above-mentioned drugs with each other or with Mucondialdehyde and / or naphthoquinones such. As 5-hydroxy-1, 4-naphthoquinone (juglone) and 2-hydroxy-1, 4-naphthoquinone proved.
• the compositions of the invention contain the self-tanner usually in concentrations of 1 to 10, in particular from 2 to 5 wt .-% - based on the total weight of the cosmetic and / or pharmaceutical preparation.
• An object of the invention relates to cosmetic and / or pharmaceutical preparations containing n-octyl n-octanoate and at least at least one self-tanner and at least one UV light protection filter.
• a preferred subject matter of the invention relates to cosmetic and / or pharmaceutical preparations containing 0.1 to 80% by weight of n-octyl n-octanoate and at least one UV light protection filter and at least one self-tanner.
• the cosmetic and / or pharmaceutical preparations according to the invention can be present, for example, as O / W or W / O care emulsions, sunscreen formulation, AP / Deo concepts, formulations for decorative cosmetics, oily care preparations, impregnating liquids for substrates such as paper and non-woven products. Examples include wet wipes, handkerchiefs, diapers or hygiene products.
• n-octyl n-octanoate according to the invention and the cosmetic and / or pharmaceutical preparations according to the invention are also particularly suitable for light, sprayable applications and / or as components of care emulsions for tissues, papers, wipes, sponges (eg polyurethane sponges), patches in the Baby Hygiene, Baby Care, Skin Care, Sunscreen, After-SunTreatment, Insect Repellent, Cleansing, Facial Cleansing and AP / Deo application.
• tissues, papers, wipes, fleece products, sponges, puffs, plasters and bandages which are used in the field of cleaning, hygiene and / or care (wet wipes for baby hygiene and baby care, cleaning wipes, Facial cleansing wipes, skin wipes, anti-aging skin wipes, wipes with sunscreen formulations and insect repellents, wipes for decorative or after-sun treatments, toilet wipes, antiperspirant wipes, diapers, handkerchiefs, wet wipes, sanitary products, self-tanning wipes, toilet paper , Refreshment towels, after-shave towels). They can be used, inter alia, in preparations for hair care, hair cleaning or hair coloring.
• the n-octyl-n-octanoate according to the invention is particularly suitable as constituents of decorative cosmetic preparations, such as lipsticks, eye make-up, such as eyeshadow, mascara, eyeliner, kohl, nail polish, etc., and make-up formulations.
• An object of the invention relates to cosmetic and / or pharmaceutical preparations containing n-octyl-n-octanoate and at least at least one pigment and / or a dye.
• a preferred subject of the invention relates to cosmetic and / or pharmaceutical preparations containing 0.1 to 80 wt .-% of n-octyl n-octanoate and at least one pigment and / or a dye.
• pigment includes particles of any shape which are white or colored, organic or inorganic, insoluble in the formulations, and serve the purpose of coloring the preparation.
• inorganic pigments are used, metal oxides are particularly preferred.
• inorganic pigments are: titanium dioxide, optionally surface-coated, zirconium or cerium oxides and zinc, iron (black, yellow or red) and chromium oxides, manganese violet, ultramarine blue, chromate and iron (III) blue, metal powder such as aluminum powder or copper powder.
• the pigment is selected from the inorganic pigments, preferably from the metal oxides.
• the pigment is selected from the group consisting of titanium dioxide, zinc oxide, iron oxide and mixtures thereof.
• the pigments can be present both individually and in mixtures.
• pigment mixtures of white pigments for example kaolin, titanium dioxide or zinc oxide
• inorganic color pigments for example iron oxide pigments, chromium oxides
• the pigments being coated (coated) or uncoated
• iron oxides are particularly preferred.
• the pigment or pigments can also be selected from the group of effect pigments, which of the cosmetic preparation in addition to the pure color an additional property - such.
• the most important group of effect pigments are the luster pigments, which according to DIN 55944: 2003-11 include the metallic effect pigments and the pearlescent pigments. Some special effect pigments can not be assigned to these two groups, z.
• luster pigments As platelet graphite, platelet-shaped iron oxide and micronized titanium dioxide, wherein micronized titanium dioxide produces no gloss effect, but an angle-dependent light scattering effect.
• the luster pigments according to DIN 55943: 2001-10 are predominantly platelet-shaped effect pigments. Parallel oriented luster pigments show a characteristic shine.
• the optical effect of luster pigments is based on the directed reflection on metallic particles (metallic effect pigments), on transparent particles with high refractive index (pearlescent pigments) or on the phenomenon of interference (interference pigments) (DIN 55944: 2003-11).
• metallic effect pigments metallic particles
• pearlescent pigments transparent particles with high refractive index
• interference pigments interference pigments
• Examples of commercially available effect pigments which are preferred according to the invention are: Timiron and # 174; from Merck, Iriodin and # 174; from Merck (pearl and color gloss pigments for decorative technical applications), Xirallic and # 174; from Merck (color intensive crystals effect pigments).
• the preparations according to the invention may advantageously also contain organic color pigments, ie. H. organic dyes which are practically insoluble in the preparation.
• organic pigments can be classified according to chemical aspects into azo pigments and polycyclic pigments as well as according to color aspects into colored or black pigments.
• Organic white pigments are of no practical importance.
• the pigments can also be used advantageously in the form of commercially available oily or aqueous predispersions.
• the preparations according to the invention usually contain from 0.1 to 40% by weight of pigments, based on the total weight of the cosmetic and / or pharmaceutical preparation.
• the preparation according to the invention contains one or more dyes.
• the dyes can be of both synthetic and natural origin. A list of suitable dyes can be found in EP 1 371 359 A2, p. 8, Z. 25-57, p. 9 and p. 10 and p. 11, p. 1 to 54, which are hereby incorporated by reference.
• the preparations according to the invention usually contain 0.01 to 5, preferably 0.1 to 1.0% by weight of dyes, based on the total weight of the cosmetic and / or pharmaceutical preparation.
• the preparations according to the invention usually contain a total amount of dyes and pigments in the range of 0.01 to 30 wt .-%, in particular 0.1 to 15 wt .-%, preferably 1 to 10 wt .-%, based on the total weight of the cosmetic and / or pharmaceutical preparation.
• Suitable dyes and pigments are, in particular, the dyes and pigments approved in accordance with Annex IV of the Commission Directive (in the version: Commission Directive 2007/22 / EC of 17 April 2007 amending Council Directive 76/768 / EEC, concerning cosmetic products, for the purposes of adapting Annexes IV and VI thermo-technical progress) substances, which are hereby explicitly referred to.
• the cosmetic and / or pharmaceutical preparations may be personal care formulations, e.g. As a body milk, creams, lotions, sprayable emulsions, products for the elimination of body odor, etc.
• the n-octyl-n-octanoates can also be used in surfactant-containing formulations such. As foam and shower baths, hair shampoos and conditioners use.
• the cosmetic and / or pharmaceutical preparations contain a number of other auxiliaries and additives, such as surfactants, other oil, emulsifiers, pearlescent, consistency, thickening, superfatting, stabilizers, polymers, fats, waxes, lecithins, phospholipids, biogenic agents , Antidandruff agents, film formers, swelling agents, insect repellents, self-tanning agents, tyrosinase inhibitors (depigmentation agents), hydro tropics, solubilizers, preservatives, perfume oils, dyes, etc., which are listed below by way of example.
• auxiliaries and additives such as surfactants, other oil, emulsifiers, pearlescent, consistency, thickening, superfatting, stabilizers, polymers, fats, waxes, lecithins, phospholipids, biogenic agents , Antidandruff agents, film formers, swelling agents, insect repellents, self-tanning agents, ty
• An object of the invention relates to cosmetic and / or pharmaceutical preparations containing n-octyl n-octanoate and at least one emulsifier and / or a surfactant and / or a wax component and / or a polymer and / or a further oil body.
• a preferred subject of the invention relates to cosmetic and / or pharmaceutical preparations containing 0.1 to 80 wt .-% of n-octyl n-octanoate and at least one emulsifier and / or a surfactant and / or a wax component and / or a polymer and / or another oil body.
• the preparations according to the invention contain at least one emulsifier.
• An object of the invention relates to cosmetic and / or pharmaceutical preparations containing n-octyl-n-octanoate and at least one emulsifier.
• a preferred subject matter of the invention relates to cosmetic and / or pharmaceutical preparations containing from 0.1 to 80% by weight of n-octyl n-octanoate and at least one emulsifier.
• the compositions according to the invention usually contain the emulsifier (s) in an amount of 0 to 40% by weight, preferably 0.1 to 20% by weight, preferably 0.1 to 15% by weight and in particular 0.1 to 10% by weight based on the total weight of the composition.
• Each emulsifier is assigned a so-called HLB value (a dimensionless number between 0 and 20) which indicates whether a preferred water or oil solubility is present. Numbers below 9 preferably indicate oil-soluble, hydrophobic emulsifiers, numbers over 11 water-soluble, hydrophilic emulsifiers.
• the HLB value says something about the balance of the size and strength of the hydrophilic and the lipophilic groups of an emulator.
• the HLB value of an emulator can also be calculated from increments, with the HLB increments for the different hydrophilic and hydrophobic groups that make up a molecule.
• the preparation according to the invention contains more than one emulsifier.
• emulsifier such as emulsifier and co-emulsifier
• the group of nonionic emulsifiers include, for example:
• Alkyl mono- and oligoglycosides having 8 to 22 carbon atoms in the alkyl radical and their ethoxylated analogs.
• polyol and in particular polyglycerol esters such as. Polyol poly-12-hydroxystearates, Polyglycerinpolyricinoleat, Polyglycerindiisostearat or Polyglycerindimerat. Also suitable are mixtures of compounds of several of these classes of substances.
• the addition products of ethylene oxide and / or of propylene oxide to fatty alcohols, fatty acids, alkylphenols, glycerol mono- and diesters and sorbitan mono- and diesters of fatty acids or castor oil are known, commercially available products. These are mixtures of homologs whose mean Alkoxyl michsgrad the ratio of the amounts of ethylene oxide and / or propylene oxide and substrate, with which the addition reaction is carried out corresponds. Depending on the degree of ethoxylation, these are W / O or O / W emulsifiers. C 12/18 fatty acid mono- and diesters of addition products of ethylene oxide with glycerol are known as refatting agents for cosmetic preparations.
• particularly useful and mild emulsifiers are polyol poly-12-hydroxystearates and mixtures thereof which, for example, under the trademarks "Dehymuls ® PGPH” (W / O emulsifier) or ⁇ umulgin ® VL 75 "(mixture of lauryl glucoside in the weight ratio 1: 1 , O / W emulsifier) or Dehymuls® ® SBL (W / O emulsifier) are marketed by Cognis Germany GmbH.
• EP is particularly directed 766661 B1 to the European Patent.
• the polyol component of these emulsifiers may be derived from substances which have at least two, preferably 3 to 12 and in particular 3 to 8 hydroxyl groups and 2 to 12 carbon atoms
• Particularly preferred emulsifiers are, for example, cetyl dimethicone copolyol (eg Abil EM-90), polyglyceryl-2 dipolyhydroxystearates (eg Dehymuls PGPH ), Polyglycerol-3-diisostearates (eg Lameform TGI), polyglyceryl-4 isostearates (eg Isolan GI 34), polyglyceryl-3 oleates (eg Isolan GO 33), diisostearoyl polyglyceryl-3 diiso stearates (eg Isolan PDI), polyglyceryl-3 methylglucose distearates (eg Tego Care 450), polyglyceryl-3 beeswax (eg Cera Bellina), poly
• a particularly effective mixture consists of polyglyceryl-2 dipolyhydroxystearates and lauryl glucosides and glycerol (eg Eumulgin VL 75). Also suitable are polyglyceryl-4 diisostearates /
• Isolan® GPS Polyhydroxystearates / sebacates
• Isolan PDI diisostearoyl polyglyceryl-3 diisostearates
• alkali salts acylglutamates e.g., Eumulgin SG
• Suitable lipophilic W / O emulsifiers are, in principle, emulsifiers having an HLB value of 1 to 8, which are summarized in numerous tables and known to the person skilled in the art. Some of these emulsifiers are listed, for example, in Kirk-Othmer, "Encyclopedia of Chemical Technology", 3rd Ed., 1979, Volume 8, page 913.
• W / O emulsifiers are partial esters of polyols, in particular of C4-C6 polyols, such as partial esters of pentaerythritol or Zuckerestem, z. B.
• Also suitable as emulsifiers are addition products of from 1 to 30, preferably from 5 to 10, mol of ethylene oxide with the stated sorbitan esters.
• At least one emulsifier from the group of nonionic O / W emulsifiers (HLB value: 8-18) and / or solubilizers are, for example, the already mentioned in the introduction ethylene oxide adducts with a correspondingly high degree of ethoxylation, z. B. 10 - 20 ethylene oxide units for O / W emulsifiers and 20 - 40 ethylene oxide units for so-called solubilizers.
• Particularly advantageous as O / W emulsifiers according to the invention are ceteareth-12 and PEG-20 stearate.
• solubilizers are Eumulgin ® HRE 40 (INCI: PEG-40 Hydrogenated Castor Oil), Eumulgin ® HRE 60 (INCI: PEG-60 Hydrogenated Castor Oil), Eumulgin ® L (INCI: PPG-1-PEG-9 Laurylglycolether) and Eumulgin ® SML 20 (INCI: polysorbate-20).
• Nonionic emulsifiers from the group of alkyl oligoglycosides are particularly skin-friendly and therefore preferably suitable as O / W emulsifiers.
• C ⁇ -C ⁇ alkyl mono- and oligoglycosides their preparation and their use are known in the art. They are prepared in particular by reacting glucose or oligosaccharides with primary alcohols having 8 to 22 carbon atoms.
• the glycoside radical both monoglycosides in which a cyclic sugar residue is glycosidically linked to the fatty alcohol and oligomeric glycosides having a degree of oligomerization of preferably approximately 8 are suitable.
• the degree of oligomerization is a statistical mean, which is based on a homolog distribution typical for such technical products.
• Products which are available under the name Plantacare ® containing a glucosidic bond Cs-Ci 6-alkyl group at an oligoglucoside whose average degree of oligomerization is 1 to the second
• the glucamine-derived acylglucamides are also suitable as nonionic emulsifiers.
• Emulgade® ® PL 68/50 by Cognis Germany GmbH and a 1: 1 mixture of alkyl polyglucosides and fatty alcohols.
• According to the invention advantageously be used is a mixture of lauryl glucoside, polyglyceryl-2-dipolyhydroxystearate, glycerine and water which is commercially available under the name Eumulgin ® VL 75 miles.
• emulsifiers are substances such as lecithins and phospholipids.
• lecithins include the cephalins, which are also referred to as phosphatidic acids and derivatives of 1,2-diacyl-sn-glycerol-3-phosphoric acids.
• phospholipids are usually understood as meaning mono- and preferably diesters of phosphoric acid with glycerol (glycerol phosphates), which are generally regarded as fats.
• sphingosines or sphingolipids are also suitable.
• silicone emulsifiers may be included. These can, for example, from the group of Alkylmethicone copolyols and / or alkyl dimethicone copolyols are selected, in particular from the group of compounds which are characterized by the following chemical structure:
• X and Y are independently selected from the group H (hydrogen) and the branched and unbranched alkyl groups, acyl groups and alkoxy groups having 1-24 carbon atoms, p is a number from 0-200, q represents a number from 1-40, and r represents a number of 1-100.
• silicone emulsifiers which are particularly advantageous for the purposes of the present invention are dimethicone copolyols which have been sold by Evonik Goldschmidt under the trade names AXIL® B 8842, ABIL® B 8843, ABIL® B 8847, ABIL® B 8851, ABIL® B 8852, ABIL® B 8863, ABIL® B 8873 and ABIL® B 88183 are sold.
• a further example of surface-active substances to be used particularly advantageously for the purposes of the present invention is the cetyl PEG / PPG-10/1 dimethicone (cetyl dimethicone copolyol) sold by Evonik Goldschmidt under the trade name ABIL® EM 90.
• a further example of surface-active substances to be used particularly advantageously for the purposes of the present invention is the cyclomethicone dimethicone copolyol sold by Evonik Goldschmidt under the trade name ABIL®EM 97 and ABIL® WE 09.
• the emulsifier Lauryl PEG / PPG-18/18 Methicone (lauryl methicone copolyol), which has been sold under the trade name Dow Corning® 5200 Formulation Aid by Dow Corning Ltd., has proved to be particularly advantageous. is available.
• Another advantageous silicone emulsifier is octyl dimethicone ethoxy glucoside from Wacker.
• Wacker For a water-in-silicone oil emulsion according to the invention, it is possible to use all known emulsifiers used for this emulsion type.
• Particularly preferred water-in-silicone emulsifiers according to the invention are cetyl PEG / PPG-10/1 dimethicones and lauryl PEG / PPG-18/18 methicones [z. B. ABIL® EM 90 Evonik Goldschmidt), DC5200 Formulation Aid (Dow Corning)] and any mixtures of both emulsifiers.
• surfactants are cetyl PEG / PPG-10/1 dimethicones and lauryl PEG / PPG-18/18 methicones [z. B. ABIL® EM 90 Evonik Goldschmidt), DC5200 Formulation Aid (Dow Corning)] and any mixtures of both emulsifiers.
• surfactants are cetyl PEG / PPG-10/1 dimethicones and lauryl PEG / PPG-18/18 methicones [z. B. ABIL® EM 90 Evonik Goldschmidt), DC5200 Formulation Aid (Dow Corning)]
• the preparations according to the invention contain at least one surfactant.
• Surfactants are amphiphilic substances that can dissolve organic, nonpolar substances in water. Due to their specific molecular structure with at least one hydrophilic and one hydrophobic part of the molecule, they provide for a lowering of the surface tension of the water, the wetting of the skin, the facilitation of dirt removal and dissolution, a gentle rinsing and, as desired, for foam regulation.
• Surfactants are usually understood to be surface-active substances which have an HLB value of greater than 20.
• An object of the invention relates to cosmetic and / or pharmaceutical preparations containing n-octyl-n-octanoate and at least one surfactant.
• a preferred subject of the invention relates to cosmetic and / or pharmaceutical preparations containing 0.1 to 80 wt .-% of n-octyl-n-octanoate and at least one surfactant.
• Surfactants which may be present are anionic, nonionic, cationic and / or amphoteric or zwitterionic surfactants.
• surfactant-containing cosmetic preparations such as shower gels, foam baths, shampoos, etc.
• at least one anionic surfactant is included.
• the compositions according to the invention usually contain the surfactant (s) in an amount of 0 to 40% by weight, preferably 0.05 to 30% by weight, in particular 0.05 to 20% by weight, preferably 0.1 to 15% by weight .-% and in particular 0.1 to 10 wt .-% based on the total weight of the composition.
• nonionic surfactants are fatty alcohol polyglycol ethers, alkylphenol polyglycol ethers, fatty acid polyglycol ethers, fatty acid amide polyglycol ethers, fatty amine polyglycol ethers, alkoxylated triglycerides, mixed ethers or optionally mixed partially oxidized alk (en) yloligoglycosides or glucuronic acid derivatives, fatty acid N-alkylglucamides, protein hydrolysates (especially vegetable hydrolysates) Wheat-based products), polyol fatty acid esters, sugar esters, sorbitan esters, polysorbates and amine oxides. If the nonionic surfactants contain polyglycol ether chains, these may have a conventional, but preferably a narrow homolog distribution.
• Zwitterionic surfactants are those surface-active compounds which carry in the molecule at least one quaternary ammonium group and at least one -COO (" '- or -SO ⁇ group.
• Particularly suitable zwitterionic surfactants are the so-called betaines, such as N-alkyl-N, N-dimethylammonium glycinates, for example cocoalkyldimethylammonium glycinate, N-acylaminopropyl N, N-dimethylammonium glycinates, for example cocoacylaminopropyldimethylammonium glycinate, and 2-alkyl-3-carboxylmethyl-3-hydroxyethylimidazoline having in each case 8 to 18 C atoms in the alkyl or acyl group and the cocoacylaminoethylhydroxyethylcarboxymethylglycinate.
• a preferred zwitterionic surfactant is the fatty acid amide derivative known by the INCI name Cocamidopropyl Betaine.
• ampholytic surfactants are understood as meaning those surface-active compounds which, apart from a C ⁇ -C 16 -alkyl or acyl group in the molecule, contain at least one free amino group and at least one -COOH or -SO 3 H group and are capable of forming internal salts.
• ampholytic surfactants are N-alkylglycines, N-alkylpropionic acids, N-alkylaminobutyric acids, N-alkyl-iminodipropionic acids, N-hydroxyethyl-N-alkylamidopropylglycines, N-alkyltaurines, N-alkylsarcosines, 2-alkylaminopropionic acids and alkylaminoacetic acids each having about 8 to 18 C atoms in the alkyl group.
• Particularly preferred ampholytic surfactants are N-cocoalkylaminopropionate, cocoacylaminoethylaminopropionate and Cu-i ⁇ -acylsarcosine.
• amphoteric or zwitterionic surfactants are alkylbetaines, alkylamidobetaines, aminopropionates, aminoglycinates, imidazolinium betaines and sulfobetaines.
• the surfactants mentioned are exclusively known compounds. As regards the structure and production of these substances, reference should be made to relevant reviews in this field.
• Typical examples of particularly suitable mild, ie particularly skin-friendly, surfactants are fatty alcohol polyglycol ether sulfates, monoglyceride sulfates, mono- and / or dialkyl sulfosuccinates, fatty acid isethionates, fatty acid sarcosinates, fatty acid taurides, fatty acid glutamates, ⁇ -olefinsulfonates, ether carboxylic acids, alkyl oligoglucosides and / or mixtures thereof with alkyl oligoglucoside carboxylates, fatty acid glucamides, alkylamidobetaines, Amphoacetals and / or protein fatty acid condensates, the latter preferably based on wheat proteins or their salts.
• Anionic surfactants are characterized by a water-solubilizing, anionic group such. As a carboxylate, sulfate, sulfonate, citrate or phosphate group and a lipophilic radical. Skin-compatible anionic surfactants are known to those skilled in large numbers from relevant manuals and commercially available.
• alkyl sulfates in the form of their alkali metal, ammonium or alkanolammonium salts
• alkyl ether sulfates in the form of their alkali metal, ammonium or alkanolammonium salts
• alkyl ether carboxylates acyl isethionates
• acylsarcosinates acyltaurines having linear alkyl or acyl groups having 12 to 18 carbon atoms
• sulfosuccinates and acylglutamates in the form of their alkali metal or ammonium salts.
• anionic surfactants are soaps, alkylbenzenesulfonates, alkanesulfonates, olefinsulfonates, alkyl ether sulfonates, glycerol ether sulfonates, ⁇ -methyl ester sulfonates, sulfo fatty acids, alkyl sulfates, glyceryl stearaate citrates, fatty alcohol ether sulfates, glycerol ether sulfates, Fatty acid ether sulfates, hydroxymethylene ether sulfates, monoglyceride (ether) sulfates,
• ether Fatty acid amide (ether) sulfates, mono- and dialkyl sulfosuccinates, mono- and dialkyl sulfosuccinamates, sulfotriglycerides, amide soaps, ether carboxy
• anionic surfactants contain polyglycol ether chains, these may have a conventional, but preferably a narrow homolog distribution.
• Quaternary ammonium compounds can be used in particular as cationic surfactants.
• the very readily biodegradable quaternary ester compounds such as the sold under the trademark Stepantex ® dialkyl ammonium methosulfates and Methylhydroxyalkyldialkoyloxyalkyl- ammonium methosulfates and the corresponding products of the Dehyquart ® series, can be used as cationic surfactants.
• the term "esterquats” is generally understood to mean quaternized fatty acid triethanolamine ester salts. They can impart a special softness to the compositions according to the invention. These are known substances which are prepared by the relevant methods of organic chemistry. Further cationic surfactants which can be used according to the invention are the quaternized protein hydrolysates.
• the preparations according to the invention contain at least one wax component.
• An object of the invention relates to cosmetic and / or pharmaceutical preparations containing n-octyl-n-octanoate and at least one wax component.
• a preferred subject matter of the invention relates to cosmetic and / or pharmaceutical preparations containing from 0.1 to 80% by weight of n-octyl n-octanoate and at least one wax component.
• the compositions of the invention contain the wax component (s) usually in an amount of 0 to 40 wt .-%, in particular from 0 to 20 wt .-%, preferably 0.1 to 15% by weight and in particular 0.1 to 10% by weight based on the total weight of the composition.
• wax is usually understood to mean all natural or artificially produced substances and mixtures with the following properties: they are harder from solid to brittle Consistency, coarse to fine crystalline, translucent to cloudy and melting above 30 0 C without decomposition. They are already slightly above the melting point low viscosity and non-stringy and show a strong temperature-dependent consistency and solubility. According to the invention use is a wax component or a mixture of wax components which melt at 30 0 C or above. Fats and fat-like substances with a waxy consistency can also be used as waxes according to the invention, as long as they have the required melting point.
• Fats include fats (triglycerides), mono- and diglycerides, natural and synthetic waxes, fatty and wax alcohols, fatty acids, esters of fatty alcohols and fatty acids and fatty acid amides or any mixtures of these substances.
• Fats are triacylglycerols, ie the triple esters of fatty acids with glycerol. Preferably, they contain saturated, unbranched and unsubstituted fatty acid residues. These may also be mixed esters, ie triple esters of glycerol with different fatty acids.
• Usable according to the invention and particularly suitable as bodying agents are so-called hardened fats and oils which are obtained by partial hydrogenation. Herbal hardened fats and oils are preferred, e.g.
• hardened castor oil peanut oil, soybean oil, rapeseed oil, rapeseed oil, cottonseed oil, soybean oil, sunflower oil, palm oil, palm kernel oil, linseed oil, almond oil, corn oil, olive oil, sesame oil, cocoa butter and coconut oil.
• Suitable include the triple esters of glycerol with C12-C60 fatty acids and in particular C12-C36 fatty acids. These include hardened castor oil, a triple ester of glycerol and a hydroxystearic acid, which is commercially available, for example, under the name Cutina HR.
• glycerol tristearate glycerol tribehenate (for.
• Example, Syncrowax HRC), glycerol or the known under the name Syncrowax HGLC triglyceride mixtures with the proviso that the melting point of the wax component or of the mixture at 30 0 C or above.
• Mono and diglycerides or mixtures of these partial glycerides can be used according to the invention as wax components.
• the glyceride mixtures which can be used according to the invention include the products marketed by Cognis GmbH & Co. KG Novata AB and Novata B (mixture of C12-C18 mono-, di- and triglycerides) and Cutina MD or Cutina GMS (glyceryl stearate).
• the fatty alcohols which can be used according to the invention as a wax component include the C12-C50 fatty alcohols.
• the fatty alcohols can be obtained from natural fats, oils and waxes, such as myristyl alcohol, 1-pentadecanol, cetyl alcohol, 1-heptadecanol, stearyl alcohol, 1-nonadecanol, arachidyl alcohol, 1-heneicosanol, behenyl alcohol, brassidyl alcohol, lignoceryl alcohol, ceryl alcohol or myricyl alcohol.
• Preferred in accordance with the invention are saturated unbranched fatty alcohols.
• unsaturated, branched or unbranched fatty alcohols can be used according to the invention as a wax component, as long as they have the required melting point.
• Fettalkohol mustarde as used in the Reduction of naturally occurring fats and oils such.
• it can also synthetic alcohols, eg.
• As the linear, even-numbered fatty alcohols of the Ziegler synthesis (Alfole) or the partially branched alcohols from the oxo synthesis (Dobanols) can be used.
• C14-C22 fatty alcohols which are particularly preferably suitable according to the invention are C14-C22 fatty alcohols which have been described, for example, by Cognis Deutschland GmbH under the name Lanette 18 (C18 alcohol), Lanette 16 (C16 alcohol), Lanette 14 (C14 alcohol), Lanette O (C16 / C18 alcohol) and Lanette 22 (C18 / C22 alcohol).
• Fatty alcohols give the compositions a drier feel on the skin than triglycerides and are therefore preferred over the latter.
• wax components it is also possible to use C14-C40 fatty acids or mixtures thereof.
• the natural waxes usable according to the invention also include the mineral waxes, such as.
• waxes such as ceresin and ozokerite or the petrochemical waxes such.
• petrolatum paraffin waxes and microwaxes.
• wax component and chemically modified waxes especially the hard waxes, such as.
• Montanesterwachse Sasol waxes and hydrogenated jojoba waxes used.
• the synthetic waxes which can be used according to the invention include, for example, waxy polyalkylene waxes and polyethylene glycol waxes. Vegetable waxes are preferred according to the invention.
• the wax component can also be selected from the group of wax esters of saturated and / or unsaturated, branched and / or unbranched alkanecarboxylic acids and saturated and / or unsaturated, branched and / or unbranched alcohols, from the group of esters of aromatic carboxylic acids, dicarboxylic acids, tricarboxylic acids or hydroxycarboxylic acids (for example 12-hydroxystearic acid) and saturated and / or unsaturated, branched and / or unbranched alcohols, and also from the group of the lactides of long-chain hydroxycarboxylic acids.
• Esters are the C16-C40 alkyl stearates, C20-C40 alkyl stearates (eg Kester wax K82H), C20-C40 dialkyl esters of dimer acids, d8-C5-alkyl hydroxystearoyl stearates or C20-C40 alkyl erucates.
• C30-C50 alkyl beeswax, tristearyl citrate, triisostearyl citrate, stearyl heptanoate, stearyl octanoate, trilauryl citrate, ethylene glycol dipalmitate, ethylene glycol distearate, ethylene glycol di (12-hydroxystearate), stearyl stearate, palmityl stearate, stearyl behenate, cetyl ester, cetearyl behenate and behenyl behenate can be used.
• fatty acid partial glycerides ie technical mono- and / or diesters of glycerol with fatty acids having 12 to 18 carbon atoms, such as glycerol mono / dilaurate, palmitate, myristate or stearate, are suitable for this purpose.
• Pearlescent waxes are also suitable as waxes.
• Pearlescent waxes in particular for use in surface-active formulations, are, for example: alkylene glycol esters, especially ethylene glycol distearate; Fatty acid alkanolamides, especially coconut fatty acid diethanolamide; Partial glycerides, especially stearic acid monoglyceride; Esters of polybasic, optionally hydroxy-substituted carboxylic acids with fatty alcohols having 6 to 22 carbon atoms, especially long-chain esters of tartaric acid; Fatty substances, such as fatty alcohols, fatty ketones, fatty aldehydes, fatty ethers and fatty carbonates, which in total have at least 24 carbon atoms, especially lauron and distearyl ether; Fatty acids such as stearic acid, hydroxystearic acid or behenic acid, ring-opening products of olefin epoxides having 12 to 22 carbon atoms with fatty alcohols having 12 to 22 carbon atoms and / or polyols
• the preparations according to the invention comprise at least one polymer.
• An object of the invention relates to cosmetic and / or pharmaceutical preparations containing n-octyl-n-octanoate and at least one polymer.
• a preferred subject matter of the invention relates to cosmetic and / or pharmaceutical preparations containing from 0.1 to 80% by weight of n-octyl n-octanoate and at least one polymer.
• the compositions according to the invention usually comprise the polymer (s) in an amount of from 0 to 20% by weight, preferably from 0.1 to 15% by weight and in particular from 0.1 to 10% by weight, based on the total weight of the Composition.
• Suitable cationic polymers are, for example, cationic cellulose derivatives, such as.
• a quaternized hydroxyethylcellulose obtainable under the name Polymer JR 400 ® from Amerchol, cationic starch, copolymers of diallyl ammonium salts and acrylamides, quaternized Vinylpyrrolidon ⁇ / inylimidazol-polymers such as Luviquat ® (BASF), condensation products of poly glycols and amines , quaternized collagen polypeptides such as lauryldimonium hydroxy propyl hydrolyzed collagen (Lamequat® ® L / Grunau), quaternized wheat polypeptides, polyethyleneimine, cationic silicone polymers such.
• quaternized cellulose derivatives such as.
• Example a quaternized hydroxyethylcellulose obtainable under the name Polymer JR 400 ® from Amerchol, cationic starch, copolymers of diallyl
• Amidomethicone, copolymers of adipic acid and dimethylaminohydroxypropyldiethylenetriamine (Cartaretine ® / Sandoz), copolymers of acrylic acid with dimethyldiallylammonium chloride (Merquat ® 550 / Chemviron), polyaminopolyamides, cationic chitin derivatives such as quaternized chitosan, optionally microcrystalline distributed, condensation products of dihaloalkylene, such as dibromobutane with bis-dialkylamines, such as. B.
• anionic, zwitterionic, amphoteric and nonionic polymers are vinyl acetate / crotonic acid copolymers, vinylpyrrolidone / vinyl acrylate copolymers,
• anionic polymers are preferred. These are preferably used in amounts of 0.1 to 5 wt .-%, preferably 0.1 to 3 wt .-% and in particular 0.1 to 2 wt .-% based on the total composition.
• Polyacrylic acid homopolymers and copolymers are preferably suitable according to the invention.
• Particularly advantageous anionic polymers are those with the INCI name Carbomer such as Carbopols of the types 980,981, 1382,2984,5984 and Rheocare C plus and Rheocare 400).
• anionic polymers are those with the INCI name Acrylates / C 10-30 alkyl acrylate crosspolymer (eg Pemulen TR, Pemulen TR 2, Carbopol 1328), acrylate copolymer (eg Rheocare TTA, TTN, TTN-2), Acrylamide / sodium acrylate copolymer (eg Cosmedia ATC), sodium polyacrylate (eg Cosmedia ATH, SP), polyacrylamides (eg Sepigel 305, 501).
• Acrylates / C 10-30 alkyl acrylate crosspolymer eg Pemulen TR, Pemulen TR 2, Carbopol 1328
• acrylate copolymer eg Rheocare TTA, TTN, TTN-2
• Acrylamide / sodium acrylate copolymer eg Cosmedia ATC
• sodium polyacrylate eg Cosmedia ATH, SP
• polyacrylamides eg Sepigel 305, 501).
• polysaccharides in particular xanthan gum, guar guar, agar agar, alginates and Tyloses and, for example, Aerosil types (hydrophilic silicas), carboxymethyl cellulose and hydroxyethyl and hydroxypropyl cellulose, polyvinyl alcohol, polyvinyl pyrrolidone and bentonites such.
• ⁇ uaternmaschinee polymers eg with the INCI name Polyquaternium-37, which correspond to the following general formula:
• dialkylaminoalkyl (meth) acrylates and their available by alkylation or protonation xcr
• Ammonium salts are used. Particularly preferred are:
• (meth) acrylamide monomers additionally contain (meth) acrylic acid and / or 2-acrylamido-2-methylpropanesulfonic acid and / or acrylamide and / or vinylpyrrolidone and / or alkyl (meth) acrylates.
• the preparations according to the invention comprise at least one oil body.
• the preparations according to the invention usually contain n-octyl n-octanoate as the oil body.
• the preparations thus comprise an oil body other than the n-octyl n-octanoate according to the invention, also referred to as "further oil body.”
• An object of the invention relates to cosmetic and / or pharmaceutical preparations containing 0.1 to 80% by weight of n-octyl n-octanoate and at least one (further) oil body.
• a preferred subject matter of the invention relates to cosmetic and / or pharmaceutical preparations containing from 0.1 to 80% by weight of n-octyl-n- octanoat, and at least one (further) oil body.
• the oil bodies are usually in a total amount of 0.1-90, in particular 0.1-80, in particular 0.5 to 70, preferably 1 to 60, in particular 1 to 50 Wt .-%, in particular 1 to 40 wt .-%, preferably 5 - 25 wt .-% and in particular 5 to 15% by weight.
• the other oil bodies are usually present in an amount of from 0.1 to 40% by weight, based on the total weight of the preparation.
• esters of Ci ⁇ -Cs ⁇ -alkylhydroxycarboxylic acids with linear or branched C6-C22 fatty alcohols in particular dioctyl malates, esters of linear and / or branched fatty acids with polyhydric alcohols (such as propylene glycol, dimerdiol or trimer triol), triglycerides are suitable Base C ⁇ -Cio fatty acids, liquid mono- / di- / triglyceride mixtures based on C6-C18 fatty acids, esters of C6-C22 fatty alcohols and / or Guerbet alcohols with aromatic carboxylic acids, especially benzoic acid, esters of C2-C12- Dicarboxylic acids with polyols having 2 to 10 carbon atoms and 2 to 6 hydroxyl groups, vegetable oils, branched primary alcohols, substituted cyclohexanes, linear and branched C6-C22 fatty alcohol carbonates, such as.
• Dicaprylyl carbonates (Cetiol® CC), Guerbet carbonates based on fatty alcohols having 6 to 18, preferably 8 to 10 C atoms, esters of benzoic acid with linear and / or branched C6-C22 alcohols (eg Finsolv® TN) , linear or branched, symmetrical or unsymmetrical dialkyl ethers having 6 to 22 carbon atoms per alkyl group, such as.
• dicaprylyl (Cetiol® OE)
• ring-opening products of epoxidized fatty acid esters with polyols and hydrocarbons or mixtures thereof are also suitable as further oil bodies are hydrocarbons, such as, for example, n-undecane and / or n-tridecane, which are available under the trade name CetioKDUT.
• silicone oils come into question. They can be present as cyclic and / or linear silicone oils. Silicone oils are high molecular weight synthetic polymeric compounds in which silicon atoms are linked in chain and / or net fashion via oxygen atoms and the remaining valencies of silicon are linked by hydrocarbon radicals (usually methyl, more rarely ethyl, propyl, phenyl groups, etc.) are saturated. Systematically, the silicone oils are called polyorganosiloxanes. The methyl-substituted polyorganosiloxanes, which are the quantitatively most important compounds of this group and are represented by the following structural formula
• Dimethicones are available in different chain lengths or with different molecular weights.
• poly(dimethylsiloxane) are, for example, dimethylpolysiloxane [poly (dimethylsiloxane)], which are obtainable, for example, under the trade names Abil 10 to 10 000 from Evonik Goldschmidt.
• phenylmethylpolysiloxane phenyl dimethicone, phenyl trimethicone
• cyclic silicones octamethylcyclotetrasiloxane or decamethylcyclopentasiloxane
• INCI cyclomethicone
• amino-modified silicones INCI: Amodimethicone
• silicone waxes eg.
• Polysiloxane-polyalkylene copolymers (INCI: stearyl dimethicone and cetyl dimethicone) and dialkoxydimethylpolysiloxanes (stearoxy dimethicone and behenoxy stearyl dimethicone) available as various Abil-Wax types from Evonik Goldschmidt.
• other silicone oils are also advantageous for the purposes of the present invention, for example cetyidimethicone, hexamethylcyclo- trisiloxane, polydimethylsiloxane, poly (methylphenylsiloxane).
• Particularly preferred silicones according to the invention are dimethicone and cyclomethicone.
• the preparations according to the invention may furthermore contain biogenic active substances, insect repellents, and
• Tyrosinase inhibitors preservatives, perfume oils, superfatting agents, stabilizers and / or
• An object of the invention relates to cosmetic and / or pharmaceutical preparations containing n-octyl-n-octanoate and at least one biogenic active ingredient, insect repellent,
• Tyrosinase inhibitor preservative, perfume oil, stabilizer and / or hydrotrope.
• a preferred subject matter of the invention relates to cosmetic and / or pharmaceutical
• Active ingredient insect repellent, tyrosinase inhibitor, preservative, perfume oil, stabilizer,
• biogenic active substances include tocopherol, tocopherol acetate, tocopherol palmitate, ascorbic acid, (deoxy) ribonucleic acid and their fragmentation products, ⁇ -glucans, retinol, bisabolol, allantoin, phytantriol, panthenol, AHA acids, amino acids, ceramides, pseudoceramides, essential oils, plant extracts, such as As aloe vera, Prunusex Consumer, Bambaranussex Exercise and vitamin complexes to understand.
• Suitable insect repellents are N, N-diethyl-m-toluamide, 1,2-pentanediol or 3- come (Nn-butyl-N-acetyl-amino) -propionic acid ethyl ester), which is sold under the name ® Insect Repellent 3535 by Merck KGaA is, as well as Butylacetylaminopropionate in question.
• Tyrosinhinbitoren that prevent the formation of melanin and find application in depigmenting, for example, arbutin, ferulic acid, kojic acid, coumaric acid and ascorbic acid (vitamin C) come into question.
• Suitable preservatives are, for example, phenoxyethanol, formaldehyde solution, parabens, pentanediol or sorbic acid and also the silver complexes known under the name Surfacine®. Also suitable as preservatives are the 1,2-alkanediols having 5 to 8 C atoms described in WO07 / 048757. Particularly suitable preservatives are those described in Annex VI of the Commission Directive (as amended by Commission Directive 2007/22 / EC of 17 April 2007 amending Council Directive 76/768 / EEC, concerning cosmetic products, for the purposes of adapting Annexes IV and VI to technical progress) substances, which are explicitly referred to here. As perfume oils are called mixtures of natural and synthetic fragrances.
• Natural fragrances are extracts of flowers, stems and leaves, fruits, fruit peel, roots, woods, herbs and grasses, needles and twigs, resins and balsams. Furthermore, animal raw materials, such as civet and Castoreum and synthetic fragrance compounds of the ester type, ethers, aldehydes, ketones, alcohols and hydrocarbons come into question.
• animal raw materials such as civet and Castoreum and synthetic fragrance compounds of the ester type, ethers, aldehydes, ketones, alcohols and hydrocarbons come into question.
• metal salts of fatty acids such as. For example, magnesium, aluminum and / or zinc stearate or ricinoleate can be used.
• Suitable fillers are compounds which z. B. further improve the sensory and cosmetic properties of the preparations and, for example, cause or enhance a velvety or silky feel on the skin (so-called. Skin sensory modifier).
• Advantageous fillers for the purposes of the present invention are starch and starch derivatives (such as, for example, tapioca starch, distarch phosphate, aluminum or sodium starch, octenylsuccinate and the like), pigments which have neither mainly UV filter nor coloring action (such as, for example, US Pat. B. boron nitride etc.) and / or Aerosils ® (CAS-No.
• PMMA polymethyl Methacrylate
• Silica eg Cosmedia ® SILC
• Stearalkonium Hectorite such as in Cosmedia® gel containing CC
• HDI / trimethylol Hexyllactone Crosspolymer such as in Cosmedia ® containing CUSHION
• hydrotropes for example, ethanol, isopropyl alcohol, or polyols.
• Polyols which are considered here preferably have Wise 2 to 15 carbon atoms and at least two hydroxyl groups.
• the polyols may contain other functional groups, in particular amino groups, or be modified with nitrogen.

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