EP2348864A4 - Composés de thiophospholipides oxydés et leurs utilisations - Google Patents
Composés de thiophospholipides oxydés et leurs utilisationsInfo
- Publication number
- EP2348864A4 EP2348864A4 EP20090818874 EP09818874A EP2348864A4 EP 2348864 A4 EP2348864 A4 EP 2348864A4 EP 20090818874 EP20090818874 EP 20090818874 EP 09818874 A EP09818874 A EP 09818874A EP 2348864 A4 EP2348864 A4 EP 2348864A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- thiophospholipid
- oxidized
- compounds
- thiophospholipid compounds
- oxidized thiophospholipid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/10—Phosphatides, e.g. lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Transplantation (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10357108P | 2008-10-08 | 2008-10-08 | |
PCT/IL2009/000949 WO2010041242A2 (fr) | 2008-10-08 | 2009-10-01 | Composés de thiophospholipides oxydés et leurs utilisations |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2348864A2 EP2348864A2 (fr) | 2011-08-03 |
EP2348864A4 true EP2348864A4 (fr) | 2013-07-31 |
Family
ID=42101031
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP20090818874 Withdrawn EP2348864A4 (fr) | 2008-10-08 | 2009-10-01 | Composés de thiophospholipides oxydés et leurs utilisations |
Country Status (3)
Country | Link |
---|---|
US (1) | US8999960B2 (fr) |
EP (1) | EP2348864A4 (fr) |
WO (1) | WO2010041242A2 (fr) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6838452B2 (en) | 2000-11-24 | 2005-01-04 | Vascular Biogenics Ltd. | Methods employing and compositions containing defined oxidized phospholipids for prevention and treatment of atherosclerosis |
US7807847B2 (en) | 2004-07-09 | 2010-10-05 | Vascular Biogenics Ltd. | Process for the preparation of oxidized phospholipids |
US9006217B2 (en) | 2007-01-09 | 2015-04-14 | Vascular Biogenics Ltd. | High-purity phospholipids |
US8569529B2 (en) | 2007-01-09 | 2013-10-29 | Vascular Biogenics Ltd. | High-purity phospholipids |
EP2348864A4 (fr) | 2008-10-08 | 2013-07-31 | Vascular Biogenics Ltd | Composés de thiophospholipides oxydés et leurs utilisations |
EP2826369A3 (fr) | 2008-11-06 | 2015-03-18 | Vascular Biogenics Ltd. | Composés lipidiques oxydés et leurs utilisations |
MX357759B (es) * | 2011-09-01 | 2018-07-24 | Vascular Biogenics Ltd | Formulaciones y formas de dosificacion de fosfolipidos oxidados. |
ES2925942T3 (es) * | 2011-12-12 | 2022-10-20 | Rhodia Operations | Sistemas de disolventes de triamidas N-alquiltiofosfóricas y métodos de uso en aplicaciones agrícolas |
WO2016084023A1 (fr) | 2014-11-26 | 2016-06-02 | Vascular Biogenics Ltd. | Lipides oxydés et traitement ou prévention de la fibrose |
US9771385B2 (en) | 2014-11-26 | 2017-09-26 | Vascular Biogenics Ltd. | Oxidized lipids |
CN110068638B (zh) * | 2019-05-21 | 2021-11-26 | 中山大学孙逸仙纪念医院 | 一种特异分离富集人血清中酸性鞘脂及糖鞘脂的方法 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070099868A1 (en) * | 2003-05-27 | 2007-05-03 | Dror Harats | Oxidized lipids and uses thereof in the treatment of inflammatory diseases and disorders |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4166132A (en) | 1977-08-18 | 1979-08-28 | Pfizer Inc. | Antiviral amine derivatives of glycerol and propanediols |
JPS5993022A (ja) | 1982-11-16 | 1984-05-29 | Kao Corp | ポリオ−ルエ−テル化合物およびその製造法ならびにこれを含有する化粧料 |
JP3128782B2 (ja) | 1992-06-12 | 2001-01-29 | 科学技術振興事業団 | 架橋高分子薄膜の製造方法 |
JPH0859545A (ja) | 1994-08-24 | 1996-03-05 | Kao Corp | カルボキシエチルエーテル誘導体及びこれを含有する洗浄剤組成物 |
US7026469B2 (en) | 2000-10-19 | 2006-04-11 | Wake Forest University School Of Medicine | Compositions and methods of double-targeting virus infections and cancer cells |
AU1846102A (en) | 2000-11-24 | 2002-06-03 | Cardimmune Ltd | Methods employing and compositions containing defined oxidized phospholipids forprevention and treatment of atherosclerosis |
US7807847B2 (en) | 2004-07-09 | 2010-10-05 | Vascular Biogenics Ltd. | Process for the preparation of oxidized phospholipids |
WO2006006161A2 (fr) | 2004-07-09 | 2006-01-19 | Vascular Biogenics Ltd. | Procede ameliore de preparation de phospholipides oxydes |
WO2007014001A2 (fr) | 2005-07-21 | 2007-02-01 | The Board Of Trustees Of The Leland Stanford Junior University | Determination multiplexee de fragments de fixation specifiques aux lipides |
US20090074720A1 (en) | 2005-10-28 | 2009-03-19 | Sabbadini Roger A | Methods for decreasing immune response and treating immune conditions |
US8703179B2 (en) | 2006-05-11 | 2014-04-22 | Kimberly-Clark Worldwide, Inc. | Mucosal formulation |
JP2008037763A (ja) | 2006-08-01 | 2008-02-21 | Adeka Corp | 抗菌剤及び抗菌剤組成物 |
US8569529B2 (en) | 2007-01-09 | 2013-10-29 | Vascular Biogenics Ltd. | High-purity phospholipids |
US9006217B2 (en) | 2007-01-09 | 2015-04-14 | Vascular Biogenics Ltd. | High-purity phospholipids |
EP2348864A4 (fr) | 2008-10-08 | 2013-07-31 | Vascular Biogenics Ltd | Composés de thiophospholipides oxydés et leurs utilisations |
EP2826369A3 (fr) | 2008-11-06 | 2015-03-18 | Vascular Biogenics Ltd. | Composés lipidiques oxydés et leurs utilisations |
JP2013516455A (ja) | 2010-01-05 | 2013-05-13 | バスキュラー バイオジェニックス リミテッド | Vb−201を用いた治療 |
MX357759B (es) | 2011-09-01 | 2018-07-24 | Vascular Biogenics Ltd | Formulaciones y formas de dosificacion de fosfolipidos oxidados. |
US20150320773A1 (en) | 2011-12-12 | 2015-11-12 | Vascular Biogenics Ltd. | Treatment of inflammation |
-
2009
- 2009-10-01 EP EP20090818874 patent/EP2348864A4/fr not_active Withdrawn
- 2009-10-01 WO PCT/IL2009/000949 patent/WO2010041242A2/fr active Application Filing
- 2009-10-01 US US13/122,766 patent/US8999960B2/en not_active Expired - Fee Related
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070099868A1 (en) * | 2003-05-27 | 2007-05-03 | Dror Harats | Oxidized lipids and uses thereof in the treatment of inflammatory diseases and disorders |
Non-Patent Citations (2)
Title |
---|
See also references of WO2010041242A2 * |
THERESA ROSARIO-JANSEN ET AL: "Phospholipids Chiral at Phosphorus. 13. Stereochemical Comparison of Phospholipase A2, Lecithin-Cholesterol Acyl Transferase, and Platelet-Activating Factor", PHOSPHORUS AND SULFUR AND THE RELATED ELEMENTS, GORDON AND BREACH - HARWOOD ACADEMIC, CH, vol. 30, no. 3-4, 1 January 1987 (1987-01-01), pages 601 - 604, XP008161110, ISSN: 0308-664X * |
Also Published As
Publication number | Publication date |
---|---|
WO2010041242A3 (fr) | 2010-06-03 |
US8999960B2 (en) | 2015-04-07 |
WO2010041242A2 (fr) | 2010-04-15 |
US20110195937A1 (en) | 2011-08-11 |
EP2348864A2 (fr) | 2011-08-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20110420 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: FEIGE, EREZ Inventor name: BREITBART, EYAL Inventor name: HALPERIN, GIDEON Inventor name: KOVALEVSKI-ISHAI, ETI Inventor name: ZINIUK, ZEEV Inventor name: MENDEL, ITZHAK |
|
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20130628 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 31/66 20060101ALI20130624BHEP Ipc: C07F 9/10 20060101ALI20130624BHEP Ipc: A01N 57/00 20060101AFI20130624BHEP |
|
17Q | First examination report despatched |
Effective date: 20140327 |
|
GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
INTG | Intention to grant announced |
Effective date: 20160212 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20160623 |