EP2323918A1 - Blister pack - Google Patents

Blister pack

Info

Publication number
EP2323918A1
EP2323918A1 EP09781315A EP09781315A EP2323918A1 EP 2323918 A1 EP2323918 A1 EP 2323918A1 EP 09781315 A EP09781315 A EP 09781315A EP 09781315 A EP09781315 A EP 09781315A EP 2323918 A1 EP2323918 A1 EP 2323918A1
Authority
EP
European Patent Office
Prior art keywords
blister pack
film
pack according
foil
containers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP09781315A
Other languages
German (de)
French (fr)
Other versions
EP2323918B1 (en
Inventor
Stephan Kurtze
Stefan Lustenberger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim International GmbH
Original Assignee
Boehringer Ingelheim International GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International GmbH filed Critical Boehringer Ingelheim International GmbH
Priority to EP09781315A priority Critical patent/EP2323918B1/en
Publication of EP2323918A1 publication Critical patent/EP2323918A1/en
Application granted granted Critical
Publication of EP2323918B1 publication Critical patent/EP2323918B1/en
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
    • A61J1/035—Blister-type containers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/325—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil
    • B65D75/327—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil and forming several compartments
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2215/00—Child-proof means
    • B65D2215/02—Child-proof means requiring the combination of simultaneous actions

Definitions

  • the invention relates to a blister pack with a bottom foil and a cover foil for forming a plurality of separable by perforations foil container, each having a receiving chamber for a product, in particular a pharmaceutical drug formulation, wherein the receiving chambers are arranged on the peripheral periphery of the blister packaging.
  • the invention further relates to a blister pack with a base film and a cover film for forming a plurality of film containers which can be separated from each other by perforations, each having a receiving chamber for a product, in particular a pharmaceutically active ingredient formulation, wherein the quadrangular film containers are arranged in a matrix.
  • foil containers serve to protect pharmaceutical active ingredient formulations against environmental influences from the outside, which under certain circumstances may influence the pharmaceutical quality of the active substance formulation, and generally consist of a cover foil and a bottom foil, wherein cavities for the filling material are formed in the bottom foil ,
  • the cover foil and the bottom foil can be made from one or multiple layers of different or the same materials.
  • the cover sheet is sealed to the bottom sheet, for example by gluing, welding or sealing.
  • the cover film and / or the bottom film are generally formed as metal and / or plastic and / or paper foil. These materials can be present in multiple layers.
  • Typical metal foils include, for example, aluminum foils and aluminum composite foils made of aluminum and, for example, a plastic.
  • polyvinyl chloride PVC
  • cycloolefin copolymer COC
  • polychlorotrifluoroethylene PCFE
  • PE polyethylene
  • PP polypropylene
  • PET polyethylene terephthalate
  • PC polycarbonate
  • polyester UP
  • PA polyac rylate
  • PCTFE polychlorotrifluoroethylene
  • PVdC polyvinylidene chloride
  • This thermoformed bottom sheet may also comprise an aluminum foil to prevent water from entering the cavity
  • the aluminum foil of the bottom foil but also the cover foil can be covered on one or both sides with further plastic and / or paper foils.
  • provisions for the infant-related packaging of medical products are being considered or already exist, in particular to make it difficult for children to access medicines that have a toxic effect or that represent a relatively high risk to health if used improperly.
  • the object is achieved in that the center of the blister pack is formed by a detachable film section, after its removal, an opening area for opening the receiving chamber is present.
  • the term "perforation" is understood to mean both an actual punching through of a material or a plurality of material layers or layers of the blister packaging and a material thinning, crease line, fold line, embossing marking or the like. Such perforations may be machined in the manufacture of the blister package to facilitate tearing or severing of individual film containers.
  • the film section is expediently assigned a perforation running around it in a circular manner.
  • the film containers can be separated segment by segment.
  • the perforation between the film containers does not extend to the outer periphery of the blister package.
  • unintentional tearing or separation of the film container along the perforations from the edge or periphery of the blister pack is effectively avoided. This allows a user the film container only from
  • the film containers are arranged with the outer contour of a polygon, circle or oval to each other net.
  • the arrangement allows a plurality of film containers to be assembled into a blister pack, wherein each film container can only be opened from the center.
  • the object of the invention in a blister pack with a bottom foil and a cover film to form a plurality separable by perforations foil container, each having a receiving chamber for a product, in particular a pharmaceutical drug formulation, wherein the square-shaped film containers are arranged in a matrix, achieved that the Film containers are spirally separable, wherein between each two adjacent film containers partially the perforation and in the region of the perforation an opening area for removal of the filling material from the receiving chamber is present.
  • Opening or the separation of the individual receiving chambers which are each filled with a pharmaceutical drug formulation specified.
  • the film containers must be separated according to a certain order, which results in a spiral, so that the user reaches the opening area.
  • the spiral shape is ensured for example by corresponding non-perforated areas between the film containers.
  • Only one opening area is provided on each film container. Due to the unusual handling a parental control is realized, because the type of opening of the receiving chamber is unusual and thus difficult for a child. An adult, on the other hand, can easily grasp and accomplish the operations for opening the receiving chamber.
  • the opening region is designed as a grip tab for removing the cover film.
  • the cover film is not fully connected in the opening area with the bottom film or less firmly sealed.
  • the cover sheet which rests relatively loosely on the bottom sheet or is relatively easy to peel off the bottom sheet in the opening area for opening the receiving chamber and for removal of the contents can be easily lifted by a user from the bottom sheet and peeled off or torn to the To be able to access contents in the receiving chamber.
  • the opening region has a notch or a cut as weakening of the bottom foil and / or the cover foil.
  • the notch or the cut extends centrally from an edge region of the film container in the direction of the receiving chamber.
  • the foil container to remove the contents is torn up to the receiving chamber.
  • the blister pack can be provided with appropriate labels or imprints consisting of digits, day of the week or the like to illustrate the correct order of removal of the contents of the receiving chambers.
  • the bottom foil preferably consists of plastic, aluminum or a composite of these materials.
  • the shape, size and number of the respective cavities of the receiving chambers in the bottom foil is matched to the male contents, such as a tablet or the like.
  • a single blister pack may comprise a plurality of film containers with the corresponding number of receiving chambers.
  • the bottom foil is, for example, on the side facing the product from an approximately 60 micron thick layer of polyvinyl chloride (PVC), followed by an approximately 45 microns thick aluminum foil, which in turn with an approximately 25 micron thick film of an oriented polyamide (oPA) is made.
  • PVC polyvinyl chloride
  • oPA oriented polyamide
  • the cover sheet is an aluminum composite foil, which, for example, on the side facing the product consists of an approximately 20 microns thick aluminum foil and an associated about 23 micron thick film of a polyethylene terephthalate (PET).
  • PET polyethylene terephthalate
  • the bottom sheet and the cover sheet may also be identical or made of other materials.
  • FIG 3 shows a plan view of a blister pack in an alternative embodiment.
  • the blister pack 7 having a plurality of film containers 1 comprises a bottom film with cavities 8 and a cover sheet which can be suitably, preferably through a
  • Heat sealing lacquer is connected to the bottom foil, in order to form in the region of the cavities 8 closed receiving chambers 2 for at least one filling material, in particular a pharmaceutical active ingredient formulation.
  • the individual film containers 1 are arranged in the form of a polygon and the individual receiving chambers 2 are located on the peripheral periphery of the blister 7.
  • a film section 4 is arranged, in which no receiving chamber 2 is formed is and which is transportedschennbar by a substantially circular perforation 3 from the blister pack 7.
  • the individual film containers 1 are separable from one another by perforations 10 which emerge from the perforation 3, wherein the perforations 10 do not extend between the film containers 1 to the periphery of the blister packaging 7, thus separating the film containers 1 from the outside difficult and easy to accomplish from the direction of the center after removing the film section 4.
  • the film section 4 To open the receiving chambers 2 of the film containers 1, the film section 4 must first be cut out in the center of the blister pack 7 along the perforation 3, which is formed continuously around its circumference. Subsequently, a user of the blister pack 7, the film container 1 separated by separating the star-shaped perforations 10 from each other, whereby the opening of the receiving chambers 2 is much easier.
  • the opening region 5 is formed as a grip tab 9 for pulling off the cover film from the bottom film, wherein the cover film in the opening region 5 is not completely connected to the bottom film or less firmly sealed.
  • FIG. 2 In the alternative embodiment of the film container 1 is shown in FIG. 2 in the opening portion 5 a section 6 as a weakening of the bottom film and the cover sheet and thus as
  • tear-open which extends from a pointing in the center of the blister pack 7 edge region of the film container 1 in the middle in the direction of the receiving chamber 2.
  • the user tears open the foil container 1 up to the receiving chamber 2.
  • the alternative blister packaging 7 square-shaped film containers 1 are arranged in matrix form, which are spirally separable. Between each two adjacent film containers 1, a perforation 11 is in regions and in the region of the perforation 11 of the opening Area 5 for removing the filling material from the receiving chamber 2 is present, wherein the opening portion 5, as explained above, may be formed. In some areas of the blister pack 7 there is no perforation 11 between the film containers 1 to ensure spiral separation. In the areas without perforation 11, a material weakening of the bottom foil and the cover foil may be formed in order to make the separation of the foil container 1 difficult, but nevertheless possible. To illustrate the order of removal of the individual film containers 1, the blister pack 7 is printed accordingly with numbers 1 to 30.

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Composite Materials (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Packages (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

A blister pack comprises a bottom film and a top film for forming a plurality of film containers (1) that can be separated from one another by perforations (10), each having one accommodating chamber (2) for a filling, particularly a pharmaceutical active substance formulation, the accommodating chambers (2) being arranged around the peripheral boundary of the blister pack (7). The centre of the blister pack (7) is formed by a detachable film section (4), after the removal of which an opening region (5) is available for opening the accommodating chamber (2).

Description

Blisterverpackung blister
Beschreibungdescription
Die Erfindung bezieht sich auf eine Blisterverpackung mit einer Bodenfolie und einer Deckfolie zur Ausbildung mehrerer durch Perforationen voneinander separierbarer Folienbehälter mit jeweils einer Aufnahmekammer für ein Füllgut, insbesondere eine pharmazeutische Wirkstoffformulierung, wobei die Aufnahmekammern am peripheren Umfang der Blister- Verpackung angeordnet sind.The invention relates to a blister pack with a bottom foil and a cover foil for forming a plurality of separable by perforations foil container, each having a receiving chamber for a product, in particular a pharmaceutical drug formulation, wherein the receiving chambers are arranged on the peripheral periphery of the blister packaging.
Im Weiteren bezieht sich die Erfindung auf eine Blisterverpackung mit einer Bodenfolie und einer Deckfolie zur Ausbildung mehrerer durch Perforationen voneinander separier- barer Folienbehälter mit jeweils einer Aufnahmekammer für ein Füllgut, insbesondere eine pharmazeutische Wirkstoff- formulierung, wobei die viereckförmigen Folienbehälter mat- rixförmig angeordnet sind.The invention further relates to a blister pack with a base film and a cover film for forming a plurality of film containers which can be separated from each other by perforations, each having a receiving chamber for a product, in particular a pharmaceutically active ingredient formulation, wherein the quadrangular film containers are arranged in a matrix.
Folienbehälter dienen unter anderem dazu, pharmazeutische Wirkstoffformulierungen vor Umwelteinflüssen von außen zu schützen, die unter Umständen die pharmazeutische Qualität der Wirkstoffformulierung beeinflussen können, und bestehen in der Regel aus einer Deckfolie und einer Bodenfolie, wo- bei in der Bodenfolie Kavitäten für das Füllgut ausgebildet sind. Die Deckfolie und die Bodenfolie können aus einer oder mehreren Schichten verschiedener oder gleicher Materialien aufgebaut sein. Die Deckfolie wird mit der Bodenfolie z.B. durch Kleben, Schweißen oder Versiegeln abgedichtet verbunden. Die Deckfolie und/oder die Bodenfolie sind in der Regel als Metall- und/oder Kunststoff- und/oder Papierfolie ausgebildet. Diese Materialien können in mehreren Schichten vorhanden sein. Typische Metallfolien umfassen beispielsweise Aluminiumfolien und Aluminiumverbundfolien, die aus Aluminium und z.B. einem Kunststoff gefertigt sind. Als Material für die Kunststofffolien kann Polyvinylchlorid (PVC) Cycloolefin-Copolymer (COC) , Polychlortrifluorethylen (PCFE) , Polyethylen (PE) , Polypropylen (PP) , Polyethylente- rephtalat (PET) , Polycarbonat (PC) , Polyester (UP) , Polyac- rylat, Polyamid (PA) oder ein anderer Kunststoff oder eine mehrschichtige Kunststoffverbundfolie, beispielsweise bestehend aus einer Kombination von Polychlortrifluorethylen (PCTFE) , das insbesondere unter dem für die Honeywell International, Inc. geschützten Handelsnamen Aclar® bekannt ist, mit Polyvinylchlorid (PVC) oder Polyvinylchlorid (PVC) mit Polyvinylidenchlorid (PVdC) , verwendet werden. Häufig besteht ein Folienbehälter bzw. Blister aus einer Deckfolie aus Aluminium, die die Bodenfolie zur Aufnahme des pharmazeutischen Produktes bzw. Wirkstoffes verschließt. Diese tiefgezogene Bodenfolie kann ebenfalls eine Aluminiumfolie umfassen, um den Eintritt von Wasser in die Kavität zurAmong other things, foil containers serve to protect pharmaceutical active ingredient formulations against environmental influences from the outside, which under certain circumstances may influence the pharmaceutical quality of the active substance formulation, and generally consist of a cover foil and a bottom foil, wherein cavities for the filling material are formed in the bottom foil , The cover foil and the bottom foil can be made from one or multiple layers of different or the same materials. The cover sheet is sealed to the bottom sheet, for example by gluing, welding or sealing. The cover film and / or the bottom film are generally formed as metal and / or plastic and / or paper foil. These materials can be present in multiple layers. Typical metal foils include, for example, aluminum foils and aluminum composite foils made of aluminum and, for example, a plastic. As the material for the plastic films, polyvinyl chloride (PVC), cycloolefin copolymer (COC), polychlorotrifluoroethylene (PCFE), polyethylene (PE), polypropylene (PP), polyethylene terephthalate (PET), polycarbonate (PC), polyester (UP), polyac rylate, polyamide (PA) or another plastic or a multilayer plastic composite film, for example consisting of a combination of polychlorotrifluoroethylene (PCTFE), which is known in particular under the trade name Aclar® protected for Honeywell International, Inc., with polyvinyl chloride (PVC) or polyvinyl chloride (PVC) with polyvinylidene chloride (PVdC). Often there is a film container or blister of a cover foil made of aluminum, which closes the bottom foil for receiving the pharmaceutical product or active ingredient. This thermoformed bottom sheet may also comprise an aluminum foil to prevent water from entering the cavity
Aufnahme des pharmazeutischen Produktes zu verhindern. Zur Schaffung einer weiteren Diffusionsbarriere bzw. zur Erhöhung der mechanischen Stabilität des Blisters kann optional die Aluminiumfolie der Bodenfolie aber auch die Deckfolie ein oder beidseitig mit weiteren Kunststoff- und/oder Papierfolien bedeckt sein. In einigen Staaten werden Vorschriften zur kindersieheren Verpackung von medizinischen Produkten in Erwägung gezogen oder existieren bereits, um insbesondere Arzneimittel, die eine toxische Wirkung aufweisen bzw. bei einer unsachgerechten Verwendung ein verhältnismäßig hohes gesundheitliches Risiko darstellen, für Kinder schwer zugänglich zu machen .To prevent ingestion of the pharmaceutical product. In order to create a further diffusion barrier or to increase the mechanical stability of the blister, optionally the aluminum foil of the bottom foil but also the cover foil can be covered on one or both sides with further plastic and / or paper foils. In some countries, provisions for the infant-related packaging of medical products are being considered or already exist, in particular to make it difficult for children to access medicines that have a toxic effect or that represent a relatively high risk to health if used improperly.
Es ist Aufgabe der Erfindung, einen Folienbehälter der eingangs genannten Art zu schaffen, bei dem die Entnahme eines Füllgutes durch die Formgebung des Folienbehälters vorgegeben ist und der eine hohe Kindersicherheit aufweist.It is an object of the invention to provide a film container of the type mentioned, in which the removal of a filling material is predetermined by the shape of the film container and has a high child safety.
Erfindungsgemäß wird die Aufgabe dadurch gelöst, dass das Zentrum der Blisterverpackung durch einen heraustrennbaren Folienabschnitt gebildet ist, nach dessen Entfernen ein Öffnungsbereich zum Öffnen der Aufnahmekammer vorhanden ist .According to the invention the object is achieved in that the center of the blister pack is formed by a detachable film section, after its removal, an opening area for opening the receiving chamber is present.
Aufgrund dieser Maßnahmen ist es erforderlich, zunächst den Folienabschnitt aus dem mittleren Bereich der Blisterverpackung heraustrennen, um nachfolgend auf den Öffnungsbereich der einzelnen Folienbehälter zugreifen zu können und die entsprechende Aufnahmekammer zur Entnahme des Füllgutes zu öffnen. Durch die Vielzahl der Handhabungsschritte ist eine zusätzliche Kindersicherung für die Blisterverpackung bereitgestellt, denn die Art der Öffnung der Aufnahmekammer ist unüblich und damit für ein Kind erschwert. Ein Erwach- sener kann dahingegen die Vorgänge zur Öffnung der Aufnahmekammer leicht erfassen und bewerkstelligen. Im Rahmen der Erfindung ist unter dem Begriff "Perforation" sowohl eine tatsächliche Durchstanzung eines Materials oder mehrerer Materiallagen oder -schichten der Blisterverpa- ckung als auch eine Materialverdünnung, Knicklinie, Falzlinie, Prägemarkierung oder dergleichen zu verstehen. Derartige Perforationen können bei der Herstellung der Blister- verpackung maschinell erzeugt werden, um das Abreißen oder Trennen einzelner Folienbehälter zu ermöglichen.Due to these measures, it is necessary to first cut out the foil section from the middle region of the blister pack in order subsequently to be able to access the opening region of the individual foil containers and to open the corresponding receiving chamber for removal of the filling material. Due to the large number of handling steps an additional child safety device for the blister pack is provided, because the type of opening of the receiving chamber is unusual and thus difficult for a child. An adult, on the other hand, can easily grasp and accomplish the operations for opening the receiving chamber. In the context of the invention, the term "perforation" is understood to mean both an actual punching through of a material or a plurality of material layers or layers of the blister packaging and a material thinning, crease line, fold line, embossing marking or the like. Such perforations may be machined in the manufacture of the blister package to facilitate tearing or severing of individual film containers.
Um das Heraustrennen des Folienabschnittes aus der Blister- verpackung zu vereinfachen, ist zweckmäßigerweise dem Folienabschnitt eine kreisförmig um diesen verlaufende Perforation zugeordnet.In order to simplify the separation of the film section from the blister packaging, the film section is expediently assigned a perforation running around it in a circular manner.
Damit ein Nutzer auch einen Teil der Blisterverpackung mit sich führen kann, sind die Folienbehälter segmentweise separierbar.So that a user can also carry a part of the blister pack, the film containers can be separated segment by segment.
Bevorzugt verläuft die Perforation zwischen den Folienbehältern nicht bis zum äußeren Umfang der Blisterverpackung. Somit ist ein auch unbeabsichtigtes Einreißen oder Abtrennen des Folienbehälters entlang der Perforationen vom Rand bzw. Umfang der Blisterverpackung her wirkungsvoll vermie- den. Dadurch kann ein Nutzer den Folienbehälter nur vomPreferably, the perforation between the film containers does not extend to the outer periphery of the blister package. Thus, unintentional tearing or separation of the film container along the perforations from the edge or periphery of the blister pack is effectively avoided. This allows a user the film container only from
Zentrum aus abtrennen, um auf die Aufnahmekammer zugreifen zu können bzw. den Folienbehälter von der restlichen Blisterverpackung abzutrennen.Separate center from in order to access the receiving chamber or to separate the film container from the remaining blister pack.
In Ausgestaltung sind die Folienbehälter mit der Außenkontur eines Vielecks, Kreises oder Ovals zueinander angeord- net. Durch die Anordnung lässt sich eine Vielzahl von Folienbehältern zu einer Blisterverpackung zusammensetzen, wobei jeder Folienbehälter nur vom Zentrum aus zu öffnen ist.In an embodiment, the film containers are arranged with the outer contour of a polygon, circle or oval to each other net. The arrangement allows a plurality of film containers to be assembled into a blister pack, wherein each film container can only be opened from the center.
Alternaiv wird die Aufgabe nach der Erfindung bei einer Blisterverpackung mit einer Bodenfolie und einer Deckfolie zur Ausbildung mehrerer durch Perforationen voneinander separierbarer Folienbehälter mit jeweils einer Aufnahmekammer für ein Füllgut, insbesondere eine pharmazeutische Wirkstoffformulierung, wobei die viereckförmigen Folienbehälter matrixförmig angeordnet sind, dadurch gelöst, dass die Folienbehälter spiralförmig separierbar sind, wobei zwischen jeweils zwei benachbarten Folienbehältern bereichsweise die Perforation und im Bereich der Perforation ein Öffnungsbereich zur Entnahme des Füllgutes aus der Aufnahmekammer vorhanden ist.Alternaively, the object of the invention in a blister pack with a bottom foil and a cover film to form a plurality separable by perforations foil container, each having a receiving chamber for a product, in particular a pharmaceutical drug formulation, wherein the square-shaped film containers are arranged in a matrix, achieved that the Film containers are spirally separable, wherein between each two adjacent film containers partially the perforation and in the region of the perforation an opening area for removal of the filling material from the receiving chamber is present.
Durch die spiralförmige Anordnung der Folienbehälter und damit auch der Aufnahmekammern ist eine Reihenfolge derDue to the spiral arrangement of the film container and thus also the receiving chambers is an order of
Öffnung bzw. der Trennung der einzelnen Aufnahmekammern, die jeweils mit einer pharmazeutischen Wirkstoffformulierung befüllt sind, vorgegeben. Die Folienbehälter müssen nach einer bestimmten Reihenfolge, die eine Spirale ergibt, separiert werden, damit der Nutzer an den Öffnungsbereich gelangt. Die Spiralform wird beispielsweise durch entsprechende nicht perforierte Bereiche zwischen den Folienbehältern sichergestellt. Selbstverständlich ist an jeden Folienbehälter nur ein Öffnungsbereich vorgesehen. Durch die unübliche Handhabung ist eine Kindersicherung realisiert, denn die Art der Öffnung der Aufnahmekammer ist unüblich und damit für ein Kind erschwert. Ein Erwachsener kann dahingegen die Vorgänge zur Öffnung der Aufnahmekammer leicht erfassen und bewerkstelligen.Opening or the separation of the individual receiving chambers, which are each filled with a pharmaceutical drug formulation specified. The film containers must be separated according to a certain order, which results in a spiral, so that the user reaches the opening area. The spiral shape is ensured for example by corresponding non-perforated areas between the film containers. Of course, only one opening area is provided on each film container. Due to the unusual handling a parental control is realized, because the type of opening of the receiving chamber is unusual and thus difficult for a child. An adult, on the other hand, can easily grasp and accomplish the operations for opening the receiving chamber.
Nach einer Weiterbildung ist der Öffnungsbereich als eine Anfasslasche zum Abziehen der Deckfolie ausgebildet. Die Deckfolie ist in dem Öffnungsbereich nicht vollflächig mit der Bodenfolie verbunden oder weniger fest gesiegelt. Somit kann die Deckfolie, die relativ lose auf der Bodenfolie aufliegt oder relativ einfach von der Bodenfolie abziehbar ist, in dem Öffnungsbereich zum Öffnen der Aufnahmekammer und zur Entnahme des Füllgutes leicht von einem Nutzer von der Bodenfolie abgehoben und abgezogen oder abgerissen werden, um auf das Füllgut in der Aufnahmekammer zugreifen zu können .According to a development, the opening region is designed as a grip tab for removing the cover film. The cover film is not fully connected in the opening area with the bottom film or less firmly sealed. Thus, the cover sheet, which rests relatively loosely on the bottom sheet or is relatively easy to peel off the bottom sheet in the opening area for opening the receiving chamber and for removal of the contents can be easily lifted by a user from the bottom sheet and peeled off or torn to the To be able to access contents in the receiving chamber.
Alternativ weist der Öffnungsbereich eine Kerbe oder einen Schnitt als Schwächung der Bodenfolie und/oder der Deckfolie auf. Zweckmäßigerweise verläuft die Kerbe bzw. der Schnitt von einem Randbereich des Folienbehälters mittig in Richtung zur Aufnahmekammer. Entlang der Kerbe oder des Schnittes ist der Folienbehälter zur Entnahme des Füllgutes bis zur Aufnahmekammer aufzureißen.Alternatively, the opening region has a notch or a cut as weakening of the bottom foil and / or the cover foil. Expediently, the notch or the cut extends centrally from an edge region of the film container in the direction of the receiving chamber. Along the notch or the cut, the foil container to remove the contents is torn up to the receiving chamber.
Selbstverständlich kann die Blisterverpackung mit entsprechenden Beschriftungen oder Aufdrucken versehen sein kann, die aus Ziffern, Wochentagsangaben oder dergleichen bestehen, um die richtige Reihenfolge der Entnahme des Füllgutes aus den Aufnahmekammern zu verdeutlichen.Of course, the blister pack can be provided with appropriate labels or imprints consisting of digits, day of the week or the like to illustrate the correct order of removal of the contents of the receiving chambers.
Bevorzugt besteht die Bodenfolie aus Kunststoff, Aluminium oder einem Verbund dieser Werkstoffe. Die Formgebung, Größe und Anzahl der jeweiligen Kavitäten der Aufnahmekammern in der Bodenfolie ist auf das aufzunehmende Füllgut, wie beispielsweise eine Tablette oder dergleichen, abgestimmt. Na- türlich kann eine einzige Blisterverpackung eine Vielzahl von Folienbehältern mit der entsprechenden Anzahl Aufnahmekammern umfassen. Die Bodenfolie ist beispielsweise auf der dem Füllgut zugewandten Seite aus einer ca. 60 μm dicken Schicht aus Polyvinylchlorid (PVC), auf die eine ca. 45 μm dicke Aluminiumfolie folgt, die wiederum mit einer ca. 25 μm dicken Folie aus einem orientierten Polyamid (oPA) verbunden ist, gefertigt.The bottom foil preferably consists of plastic, aluminum or a composite of these materials. The shape, size and number of the respective cavities of the receiving chambers in the bottom foil is matched to the male contents, such as a tablet or the like. Of course, a single blister pack may comprise a plurality of film containers with the corresponding number of receiving chambers. The bottom foil is, for example, on the side facing the product from an approximately 60 micron thick layer of polyvinyl chloride (PVC), followed by an approximately 45 microns thick aluminum foil, which in turn with an approximately 25 micron thick film of an oriented polyamide ( oPA) is made.
Vorteilhafterweise ist die Deckfolie eine Aluminium- Verbundfolie, die beispielsweise auf der dem Füllgut zugewandten Seite aus einer ca. 20 um dicken Aluminiumfolie und einer damit verbundenen ca. 23 μm dicken Folie aus einem Polyethylenterephtalat (PET) besteht. Selbstverständlich können die Bodenfolie und die Deckfolie auch identisch sein oder aus anderen Materialien gefertigt werden.Advantageously, the cover sheet is an aluminum composite foil, which, for example, on the side facing the product consists of an approximately 20 microns thick aluminum foil and an associated about 23 micron thick film of a polyethylene terephthalate (PET). Of course, the bottom sheet and the cover sheet may also be identical or made of other materials.
Es versteht sich, dass die vorstehend genannten und nachstehend noch zu erläuternden Merkmale nicht nur in der jeweils angegebenen Kombination, sondern auch in anderen Kom- binationen verwendbar sind. Der Rahmen der Erfindung ist nur durch die Ansprüche definiert.It goes without saying that the features mentioned above and those yet to be explained below can be used not only in the respectively specified combination but also in other combinations. The scope of the invention is defined only by the claims.
Die Erfindung wird im Folgenden anhand mehrerer Ausführungsbeispiele unter Bezugnahme auf die zugehörige Zeich- nung näher erläutert. Es zeigt: Fig.l eine Draufsicht auf eine erfindungsgemäße Blister- verpackung,The invention will be explained in more detail below with reference to several embodiments with reference to the accompanying drawings. It shows: 1 shows a plan view of a blister pack according to the invention,
Fig.2 eine Draufsicht auf einen alternativen Folienbehälter der Blisterverpackung nach Fig. 1 und2 shows a plan view of an alternative film container of the blister pack according to FIG. 1 and FIG
Fig.3 eine Draufsicht auf eine Blisterverpackung in alternativer Ausgestaltung.3 shows a plan view of a blister pack in an alternative embodiment.
Die mehrere Folienbehälter 1 aufweisende Blisterverpackung 7 umfasst eine Bodenfolie mit Kavitäten 8 und eine Deckfo- lie, die in geeigneter Weise, vorzugsweise durch einenThe blister pack 7 having a plurality of film containers 1 comprises a bottom film with cavities 8 and a cover sheet which can be suitably, preferably through a
Heißsiegellack, mit der Bodenfolie verbunden ist, um im Bereich der Kavitäten 8 geschlossene Aufnahmekammern 2 für jeweils mindestens ein Füllgut, insbesondere eine pharmazeutische Wirkstoffformulierung, zu bilden.Heat sealing lacquer, is connected to the bottom foil, in order to form in the region of the cavities 8 closed receiving chambers 2 for at least one filling material, in particular a pharmaceutical active ingredient formulation.
Nach Fig. 1 sind bei der Blisterverpackung 7 die einzelnen Folienbehälter 1 in Form eines Vielecks zueinander angeordnet und die einzelnen Aufnahmekammern 2 befinden sich am peripheren Umfang der Blisterverpackung 7. Im Zentrum der Blisterverpackung 7 ist ein Folienabschnitt 4 angeordnet, in dem keine Aufnahmekammer 2 ausgebildet ist und der durch eine im Wesentlichen kreisförmige Perforation 3 aus der Blisterverpackung 7 heraustrennbar ist. An den Folienabschnitt 4 schließen sich definierte Öffnungsbereiche 5 zum Öffnen der Aufnahmekammern 2 der segmentförmigen Folienbehälter 1 an. Die einzelnen Folienbehälter 1 sind durch Perforationen 10, die von der Perforation 3 abgehen, voneinander trennbar, wobei sich die Perforationen 10 zwischen den Folienbehältern 1 nicht bis zum Umfang der Blisterverpa- ckung 7 erstrecken, damit ein Abtrennen der Folienbehälter 1 von außen schwer und aus der Richtung des Zentrums nach dem Entfernen des Folienabschnittes 4 leicht zu bewerkstelligen ist.1, the individual film containers 1 are arranged in the form of a polygon and the individual receiving chambers 2 are located on the peripheral periphery of the blister 7. In the center of the blister 7 a film section 4 is arranged, in which no receiving chamber 2 is formed is and which is herausschennbar by a substantially circular perforation 3 from the blister pack 7. Defined opening regions 5 for opening the receiving chambers 2 of the segment-shaped film containers 1 adjoin the film section 4. The individual film containers 1 are separable from one another by perforations 10 which emerge from the perforation 3, wherein the perforations 10 do not extend between the film containers 1 to the periphery of the blister packaging 7, thus separating the film containers 1 from the outside difficult and easy to accomplish from the direction of the center after removing the film section 4.
Zum Öffnen der Aufnahmekammern 2 der Folienbehälter 1 muss zunächst der Folienabschnitt 4 im Zentrum der Blisterverpa- ckung 7 entlang der Perforation 3 , die um seinen Umfang durchgehend ausgebildet ist, herausgetrennt werden. Nachfolgend kann ein Nutzer der Blisterverpackung 7 die Folien- behälter 1 durch Auftrennen der sternförmig verlaufenden Perforationen 10 von einander trennen, wodurch das Öffnen der Aufnahmekammern 2 wesentlich erleichtert ist. Der Öffnungsbereich 5 ist als eine Anfasslasche 9 zum Abziehen der Deckfolie von der Bodenfolie ausgebildet, wobei die Deckfo- lie in dem Öffnungsbereich 5 nicht vollflächig mit der Bodenfolie verbunden oder weniger fest gesiegelt ist.To open the receiving chambers 2 of the film containers 1, the film section 4 must first be cut out in the center of the blister pack 7 along the perforation 3, which is formed continuously around its circumference. Subsequently, a user of the blister pack 7, the film container 1 separated by separating the star-shaped perforations 10 from each other, whereby the opening of the receiving chambers 2 is much easier. The opening region 5 is formed as a grip tab 9 for pulling off the cover film from the bottom film, wherein the cover film in the opening region 5 is not completely connected to the bottom film or less firmly sealed.
Bei der alternativen Ausführung des Folienbehälters 1 ist gemäß Fig. 2 in dem Öffnungsbereich 5 ein Schnitt 6 als Schwächung der Bodenfolie und der Deckfolie und damit alsIn the alternative embodiment of the film container 1 is shown in FIG. 2 in the opening portion 5 a section 6 as a weakening of the bottom film and the cover sheet and thus as
Aufreißhilfe vorgesehen, der von einem in das Zentrum der Blisterverpackung 7 weisenden Randbereich des Folienbehälters 1 mittig in Richtung der Aufnahmekammer 2 verläuft. Zur Entnahme des Füllgutes reißt der Nutzer den Folienbe- hälter 1 bis zur Aufnahmekammer 2 auf.Provided tear-open, which extends from a pointing in the center of the blister pack 7 edge region of the film container 1 in the middle in the direction of the receiving chamber 2. To remove the filling material, the user tears open the foil container 1 up to the receiving chamber 2.
Nach Fig. 3 sind bei der alternativen Blisterverpackung 7 viereckförmige Folienbehälter 1 matrixförmig angeordnet, die spiralförmig separierbar sind. Zwischen jeweils zwei benachbarten Folienbehältern 1 ist bereichsweise eine Perforation 11 und im Bereich der Perforation 11 der Öffnungs- bereich 5 zur Entnahme des Füllgutes aus der Aufnahmekammer 2 vorhanden, wobei der Öffnungsbereich 5, wie zuvor erläutert, ausgebildet sein kann. In einigen Bereichen der Blisterverpackung 7 ist zwischen den Folienbehältern 1 kei- ne Perforation 11 vorhanden, um das spiralförmige Separieren sicherzustellen. In den Bereichen ohne Perforation 11 kann eine Materialschwächung der Bodenfolie und der Deckfolie ausgebildet sein, um das Abtrennen der Folienbehälter 1 zwar zu erschweren, aber dennoch zu ermöglichen. Zur Veran- schaulichung der Reihenfolge der Entnahme der einzelnen Folienbehälter 1 ist die Blisterverpackung 7 mit Ziffern 1 bis 30 entsprechend bedruckt. According to FIG. 3, in the alternative blister packaging 7, square-shaped film containers 1 are arranged in matrix form, which are spirally separable. Between each two adjacent film containers 1, a perforation 11 is in regions and in the region of the perforation 11 of the opening Area 5 for removing the filling material from the receiving chamber 2 is present, wherein the opening portion 5, as explained above, may be formed. In some areas of the blister pack 7 there is no perforation 11 between the film containers 1 to ensure spiral separation. In the areas without perforation 11, a material weakening of the bottom foil and the cover foil may be formed in order to make the separation of the foil container 1 difficult, but nevertheless possible. To illustrate the order of removal of the individual film containers 1, the blister pack 7 is printed accordingly with numbers 1 to 30.

Claims

Patentansprüche claims
1. Blisterverpackung mit einer Bodenfolie und einer Deckfolie zur Ausbildung mehrerer durch Perforationen (10) voneinander separierbarer Folienbehälter (1) mit jeweils einer Aufnahmekammer (2) für ein Füllgut, insbesondere eine pharmazeutische Wirkstoffformulierung, wobei die Aufnahmekammern (2) am peripheren Umfang der Blisterverpackung (7) angeordnet sind, dadurch gekennzeichnet, dass das Zentrum der Blisterverpackung (7) durch einen heraustrennbaren Folienabschnitt (4) gebildet ist, nach dessen Entfernen ein Öffnungsbereich (5) zum Öffnen der Aufnahmekammer (2) vorhanden ist.1. blister pack with a bottom sheet and a cover sheet to form a plurality of perforations (10) separable from each other film container (1) each having a receiving chamber (2) for a product, in particular a pharmaceutical drug formulation, wherein the receiving chambers (2) on the peripheral periphery of the blister (7) are arranged, characterized in that the center of the blister pack (7) by a detachable film section (4) is formed, after its removal, an opening portion (5) for opening the receiving chamber (2) is present.
2. Blisterverpackung nach Anspruch 1, dadurch gekennzeichnet, dass dem Folienabschnitt (4) eine kreisförmig um diesen verlaufende Perforation (3) zugeordnet ist.2. blister pack according to claim 1, characterized in that the film section (4) is associated with a circular extending around this perforation (3).
3. Blisterverpackung nach Anspruch 1, dadurch gekennzeichnet, dass die Folienbehälter (1) segmentweise separierbar sind.3. blister pack according to claim 1, characterized in that the film containers (1) are segmentally separable.
4. Blisterverpackung nach einem der Ansprüche 1 bis 3, dadurch gekennzeichnet, dass die Perforation (10) zwischen den Folienbehältern (1) nicht bis zum äußeren Umfang der Blisterverpackung (7) verläuft.4. blister pack according to one of claims 1 to 3, characterized in that the perforation (10) between the film containers (1) does not extend to the outer periphery of the blister pack (7).
5. Blisterverpackung nach einem der Ansprüche 1 bis 4, dadurch gekennzeichnet/ dass die Folienbehälter (1) mit der Außenkontur eines Vielecks, Kreises oder Ovals zueinander angeordnet sind.5. blister pack according to one of claims 1 to 4, characterized in / that the film container (1) are arranged with the outer contour of a polygon, circle or oval with each other.
6. Blisterverpackung mit einer Bodenfolie und einer Deckfolie zur Ausbildung mehrerer durch Perforationen (11) voneinander separierbarer Folienbehälter (1) mit jeweils einer Aufnahmekainmer (2) für ein Füllgut, insbesondere eine pharmazeutische Wirkstoffformulierung, wobei die viereckförmigen Folienbehälter (1) matrix- förmig angeordnet sind, dadurch gekennzeichnet, dass die Folienbehälter (1) spiralförmig separierbar sind, wobei zwischen jeweils zwei benachbarten Folienbehältern (1) bereichsweise die Perforation (11) und im Be- reich der Perforation (11) ein Öffnungsbereich (5) zur Entnahme des Füllgutes aus der Aufnahmekarnmer (2) vorhanden ist.6. blister pack with a bottom foil and a cover sheet for forming a plurality of perforations (11) separable from each other film containers (1) each having a Aufnahmekainmer (2) for a product, in particular a pharmaceutical drug formulation, the square-shaped foil container (1) arranged in a matrix characterized in that the film containers (1) are spirally separable, wherein between each two adjacent film containers (1) partially the perforation (11) and in the area of the perforation (11) an opening area (5) for removal of the filling the Aufnahmekarnmer (2) is present.
7. Blisterverpackung nach einem der Ansprüche 1 bis 6, dadurch gekennzeichnet, dass der Öffnungsbereich (5) als eine Anfasslasche (9) zum Abziehen der Deckfolie ausgebildet ist.7. blister pack according to one of claims 1 to 6, characterized in that the opening portion (5) is designed as a grip tab (9) for removing the cover sheet.
8. Blisterverpackung nach einem der Ansprüche 1 bis 6, dadurch gekennzeichnet, dass der Öffnungsbereich (5) eine Kerbe oder einen Schnitt (6) als Schwächung der Bodenfolie und/oder der Deckfolie aufweist.8. blister pack according to one of claims 1 to 6, characterized in that the opening portion (5) has a notch or a section (6) as a weakening of the bottom foil and / or the cover sheet.
9. Blisterverpackung nach Anspruch 8, dadurch gekenn- zeichnet, dass die Kerbe bzw. der Schnitt (6) von einem Randbereich des Folienbehälters (1) mittig in Richtung zur Aufnahmekammer (2) verläuft.9. blister pack according to claim 8, characterized in that the notch or the cut (6) from an edge region of the film container (1) in the middle in Direction to the receiving chamber (2) extends.
10. Blisterverpackung nach einem der Ansprüche 1 bis 9, gekennzeichnet durch Beschriftungen oder Aufdrucke, die aus Ziffern, Wochentagsangaben oder dergleichen bestehen.10. blister pack according to one of claims 1 to 9, characterized by labels or imprints consisting of digits, day of the week or the like.
11. Blisterverpackung nach einem der Ansprüche 1 bis 10, dadurch gekennzeichnet, dass die Bodenfolie aus Kunst- stoff, Aluminium oder einem Verbund dieser Werkstoffe besteht .11. blister pack according to one of claims 1 to 10, characterized in that the bottom foil made of plastic, aluminum or a composite of these materials.
12. Blisterverpackung nach einem der Ansprüche 1 bis 10, dadurch gekennzeichnet, dass die Deckfolie eine Alumi- nium-Verbundfolie ist. 12. blister pack according to one of claims 1 to 10, characterized in that the cover sheet is an aluminum composite foil.
EP09781315A 2008-08-11 2009-07-30 Blister pack Not-in-force EP2323918B1 (en)

Priority Applications (1)

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EP09781315A EP2323918B1 (en) 2008-08-11 2009-07-30 Blister pack

Applications Claiming Priority (3)

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EP08162175 2008-08-11
EP09781315A EP2323918B1 (en) 2008-08-11 2009-07-30 Blister pack
PCT/EP2009/059906 WO2010018077A1 (en) 2008-08-11 2009-07-30 Blister pack

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EP2323918A1 true EP2323918A1 (en) 2011-05-25
EP2323918B1 EP2323918B1 (en) 2012-02-01

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US (2) US20110198261A1 (en)
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JP (1) JP5314139B2 (en)
AT (1) ATE543743T1 (en)
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EP2323918B1 (en) 2012-02-01
ATE543743T1 (en) 2012-02-15
US20130153460A1 (en) 2013-06-20
JP5314139B2 (en) 2013-10-16
WO2010018077A1 (en) 2010-02-18
JP2011530460A (en) 2011-12-22
US20110198261A1 (en) 2011-08-18
CA2733495A1 (en) 2010-02-18

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