EP2304420A4 - METHODS AND APPARATUS FOR DETECTING MOLECULAR INTERACTIONS USING FET ARRAYS - Google Patents

METHODS AND APPARATUS FOR DETECTING MOLECULAR INTERACTIONS USING FET ARRAYS

Info

Publication number
EP2304420A4
EP2304420A4 EP09770544.6A EP09770544A EP2304420A4 EP 2304420 A4 EP2304420 A4 EP 2304420A4 EP 09770544 A EP09770544 A EP 09770544A EP 2304420 A4 EP2304420 A4 EP 2304420A4
Authority
EP
European Patent Office
Prior art keywords
arrays
methods
fet
improved
molecular interactions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP09770544.6A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP2304420A2 (en
Inventor
Jonathan M Rothberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Life Technologies Corp
Original Assignee
Life Technologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Life Technologies Corp filed Critical Life Technologies Corp
Priority to EP19193875.2A priority Critical patent/EP3650847A1/en
Publication of EP2304420A2 publication Critical patent/EP2304420A2/en
Publication of EP2304420A4 publication Critical patent/EP2304420A4/en
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403—Cells and electrode assemblies
    • G01N27/414—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
    • G01N27/4145—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS specially adapted for biomolecules, e.g. gate electrode with immobilised receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403—Cells and electrode assemblies
    • G01N27/414—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
    • G01N27/4148—Integrated circuits therefor, e.g. fabricated by CMOS processing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Electrochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP09770544.6A 2008-06-26 2009-06-26 METHODS AND APPARATUS FOR DETECTING MOLECULAR INTERACTIONS USING FET ARRAYS Ceased EP2304420A4 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP19193875.2A EP3650847A1 (en) 2008-06-26 2009-06-26 Methods and apparatus for detecting molecular interactions using fet arrays

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13320408P 2008-06-26 2008-06-26
PCT/US2009/003797 WO2009158006A2 (en) 2008-06-26 2009-06-26 Methods and apparatus for detecting molecular interactions using fet arrays

Related Child Applications (1)

Application Number Title Priority Date Filing Date
EP19193875.2A Division EP3650847A1 (en) 2008-06-26 2009-06-26 Methods and apparatus for detecting molecular interactions using fet arrays

Publications (2)

Publication Number Publication Date
EP2304420A2 EP2304420A2 (en) 2011-04-06
EP2304420A4 true EP2304420A4 (en) 2013-10-30

Family

ID=41445144

Family Applications (2)

Application Number Title Priority Date Filing Date
EP19193875.2A Pending EP3650847A1 (en) 2008-06-26 2009-06-26 Methods and apparatus for detecting molecular interactions using fet arrays
EP09770544.6A Ceased EP2304420A4 (en) 2008-06-26 2009-06-26 METHODS AND APPARATUS FOR DETECTING MOLECULAR INTERACTIONS USING FET ARRAYS

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP19193875.2A Pending EP3650847A1 (en) 2008-06-26 2009-06-26 Methods and apparatus for detecting molecular interactions using fet arrays

Country Status (4)

Country Link
EP (2) EP3650847A1 (enExample)
JP (1) JP2011525990A (enExample)
CN (1) CN102203597A (enExample)
WO (1) WO2009158006A2 (enExample)

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US11435358B2 (en) 2011-06-23 2022-09-06 Board Of Regents, The University Of Texas System Single molecule peptide sequencing
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US9970984B2 (en) 2011-12-01 2018-05-15 Life Technologies Corporation Method and apparatus for identifying defects in a chemical sensor array
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US9646132B2 (en) 2012-05-11 2017-05-09 Life Technologies Corporation Models for analyzing data from sequencing-by-synthesis operations
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US10329608B2 (en) 2012-10-10 2019-06-25 Life Technologies Corporation Methods, systems, and computer readable media for repeat sequencing
JP6031954B2 (ja) * 2012-11-14 2016-11-24 ソニー株式会社 発光素子、表示装置及び電子機器
US9080968B2 (en) 2013-01-04 2015-07-14 Life Technologies Corporation Methods and systems for point of use removal of sacrificial material
US9841398B2 (en) 2013-01-08 2017-12-12 Life Technologies Corporation Methods for manufacturing well structures for low-noise chemical sensors
US8962366B2 (en) 2013-01-28 2015-02-24 Life Technologies Corporation Self-aligned well structures for low-noise chemical sensors
US8841217B1 (en) 2013-03-13 2014-09-23 Life Technologies Corporation Chemical sensor with protruded sensor surface
US8963216B2 (en) 2013-03-13 2015-02-24 Life Technologies Corporation Chemical sensor with sidewall spacer sensor surface
EP3249057B1 (en) * 2013-03-14 2019-05-01 Life Technologies Corporation Matrix arrays and methods for making same
US20140296080A1 (en) 2013-03-14 2014-10-02 Life Technologies Corporation Methods, Systems, and Computer Readable Media for Evaluating Variant Likelihood
JP6671274B2 (ja) 2013-03-15 2020-03-25 ライフ テクノロジーズ コーポレーション 薄伝導性素子を有する化学装置
US9835585B2 (en) 2013-03-15 2017-12-05 Life Technologies Corporation Chemical sensor with protruded sensor surface
US9116117B2 (en) 2013-03-15 2015-08-25 Life Technologies Corporation Chemical sensor with sidewall sensor surface
WO2014149778A1 (en) 2013-03-15 2014-09-25 Life Technologies Corporation Chemical sensors with consistent sensor surface areas
JP2016510895A (ja) 2013-03-15 2016-04-11 ライフ テクノロジーズ コーポレーション 一貫性のあるセンサ表面積を有する化学センサ
US20140336063A1 (en) 2013-05-09 2014-11-13 Life Technologies Corporation Windowed Sequencing
US10458942B2 (en) 2013-06-10 2019-10-29 Life Technologies Corporation Chemical sensor array having multiple sensors per well
JP6532456B2 (ja) 2013-10-04 2019-06-19 ライフ テクノロジーズ コーポレーション 終止化学を用いる配列決定における整相効果（ｐｈａｓｉｎｇ ｅｆｆｅｃｔｓ）をモデル化するための方法及びシステム
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WO2016060974A1 (en) 2014-10-13 2016-04-21 Life Technologies Corporation Methods, systems, and computer-readable media for accelerated base calling
TWI684004B (zh) 2014-12-18 2020-02-01 美商生命技術公司 用於使用大規模fet陣列量測分析物之方法及設備
US10605767B2 (en) 2014-12-18 2020-03-31 Life Technologies Corporation High data rate integrated circuit with transmitter configuration
US10077472B2 (en) 2014-12-18 2018-09-18 Life Technologies Corporation High data rate integrated circuit with power management
CN104730137A (zh) * 2015-03-27 2015-06-24 中国科学院上海微系统与信息技术研究所 基于超薄绝缘层soi上的mosfet背栅生物传感器及其制备方法
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US9678037B2 (en) 2015-10-08 2017-06-13 The Regents Of The University Of Michigan Two-dimensional material-based field-effect transistor sensors
CN105543071A (zh) * 2015-12-10 2016-05-04 严媚 一种用于高通量基因测序的cmos isfet双模式图像化学传感器芯片
CN105758919A (zh) * 2016-03-01 2016-07-13 杭州格磊思沃科技有限公司 半导体疾病芯片的制造方法
US10619205B2 (en) 2016-05-06 2020-04-14 Life Technologies Corporation Combinatorial barcode sequences, and related systems and methods
US10724089B2 (en) 2016-10-06 2020-07-28 The Board Of Trustees Of The University Of Illinois Spatial molecular analysis of tissue
CN110312932B (zh) * 2016-11-07 2021-12-21 Dnae诊断有限公司 化学敏感场效应晶体管阵列
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CN108732225B (zh) * 2017-04-19 2021-07-13 中芯国际集成电路制造(上海)有限公司 离子敏感场效应晶体管及其形成方法
EP3821010A4 (en) 2018-07-12 2022-04-20 Board of Regents, The University of Texas System Molecular neighborhood detection by oligonucleotides
JP2022504225A (ja) 2018-10-05 2022-01-13 ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム 固相でのｎ末端ペプチド捕捉および解放の方法
JP7687953B2 (ja) * 2019-01-23 2025-06-03 ベクトン・ディキンソン・アンド・カンパニー 連続実時間血液培養測定のためのデバイス、システム、及び方法
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Also Published As

Publication number Publication date
CN102203597A (zh) 2011-09-28
JP2011525990A (ja) 2011-09-29
WO2009158006A2 (en) 2009-12-30
EP3650847A1 (en) 2020-05-13
EP2304420A2 (en) 2011-04-06
WO2009158006A3 (en) 2010-05-06

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