EP2304420A4 - Verfahren und vorrichtung zum nachweis molekularer wechselwirkungen unter verwendung von fet-arrays - Google Patents

Verfahren und vorrichtung zum nachweis molekularer wechselwirkungen unter verwendung von fet-arrays

Info

Publication number
EP2304420A4
EP2304420A4 EP09770544.6A EP09770544A EP2304420A4 EP 2304420 A4 EP2304420 A4 EP 2304420A4 EP 09770544 A EP09770544 A EP 09770544A EP 2304420 A4 EP2304420 A4 EP 2304420A4
Authority
EP
European Patent Office
Prior art keywords
arrays
methods
fet
improved
molecular interactions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP09770544.6A
Other languages
English (en)
French (fr)
Other versions
EP2304420A2 (de
Inventor
Jonathan M Rothberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Life Technologies Corp
Original Assignee
Life Technologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Life Technologies Corp filed Critical Life Technologies Corp
Priority to EP19193875.2A priority Critical patent/EP3650847A1/de
Publication of EP2304420A2 publication Critical patent/EP2304420A2/de
Publication of EP2304420A4 publication Critical patent/EP2304420A4/de
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403—Cells and electrode assemblies
    • G01N27/414—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
    • G01N27/4145—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS specially adapted for biomolecules, e.g. gate electrode with immobilised receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403—Cells and electrode assemblies
    • G01N27/414—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
    • G01N27/4148—Integrated circuits therefor, e.g. fabricated by CMOS processing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Electrochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP09770544.6A 2008-06-26 2009-06-26 Verfahren und vorrichtung zum nachweis molekularer wechselwirkungen unter verwendung von fet-arrays Ceased EP2304420A4 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP19193875.2A EP3650847A1 (de) 2008-06-26 2009-06-26 Verfahren und vorrichtung zum nachweis molekularer wechselwirkungen unter verwendung von fet-arrays

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13320408P 2008-06-26 2008-06-26
PCT/US2009/003797 WO2009158006A2 (en) 2008-06-26 2009-06-26 Methods and apparatus for detecting molecular interactions using fet arrays

Related Child Applications (1)

Application Number Title Priority Date Filing Date
EP19193875.2A Division EP3650847A1 (de) 2008-06-26 2009-06-26 Verfahren und vorrichtung zum nachweis molekularer wechselwirkungen unter verwendung von fet-arrays

Publications (2)

Publication Number Publication Date
EP2304420A2 EP2304420A2 (de) 2011-04-06
EP2304420A4 true EP2304420A4 (de) 2013-10-30

Family

ID=41445144

Family Applications (2)

Application Number Title Priority Date Filing Date
EP09770544.6A Ceased EP2304420A4 (de) 2008-06-26 2009-06-26 Verfahren und vorrichtung zum nachweis molekularer wechselwirkungen unter verwendung von fet-arrays
EP19193875.2A Pending EP3650847A1 (de) 2008-06-26 2009-06-26 Verfahren und vorrichtung zum nachweis molekularer wechselwirkungen unter verwendung von fet-arrays

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP19193875.2A Pending EP3650847A1 (de) 2008-06-26 2009-06-26 Verfahren und vorrichtung zum nachweis molekularer wechselwirkungen unter verwendung von fet-arrays

Country Status (4)

Country Link
EP (2) EP2304420A4 (de)
JP (1) JP2011525990A (de)
CN (1) CN102203597A (de)
WO (1) WO2009158006A2 (de)

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US8776573B2 (en) 2009-05-29 2014-07-15 Life Technologies Corporation Methods and apparatus for measuring analytes
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US8052931B2 (en) * 2010-01-04 2011-11-08 International Business Machines Corporation Ultra low-power CMOS based bio-sensor circuit
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US11307166B2 (en) 2010-07-01 2022-04-19 Life Technologies Corporation Column ADC
EP2617061B1 (de) 2010-09-15 2021-06-30 Life Technologies Corporation Verfahren und vorrichtung zur analytmessung
US8685324B2 (en) 2010-09-24 2014-04-01 Life Technologies Corporation Matched pair transistor circuits
EP2625287A1 (de) 2010-10-08 2013-08-14 DNA Electronics Ltd Ionensignalverstärkung
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EP3141614B1 (de) 2010-10-27 2018-11-28 Life Technologies Corporation Prädiktives modell zur verwendung für sequenzierung nach synthese
US10273540B2 (en) 2010-10-27 2019-04-30 Life Technologies Corporation Methods and apparatuses for estimating parameters in a predictive model for use in sequencing-by-synthesis
US9594870B2 (en) 2010-12-29 2017-03-14 Life Technologies Corporation Time-warped background signal for sequencing-by-synthesis operations
WO2012092515A2 (en) 2010-12-30 2012-07-05 Life Technologies Corporation Methods, systems, and computer readable media for nucleic acid sequencing
US10146906B2 (en) 2010-12-30 2018-12-04 Life Technologies Corporation Models for analyzing data from sequencing-by-synthesis operations
US20130060482A1 (en) 2010-12-30 2013-03-07 Life Technologies Corporation Methods, systems, and computer readable media for making base calls in nucleic acid sequencing
US8594951B2 (en) 2011-02-01 2013-11-26 Life Technologies Corporation Methods and systems for nucleic acid sequence analysis
WO2012138921A1 (en) 2011-04-08 2012-10-11 Life Technologies Corporation Phase-protecting reagent flow orderings for use in sequencing-by-synthesis
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ES2919859T3 (es) * 2011-12-22 2022-07-28 Becton Dickinson Co Métodos y aparato para la detección rápida de microorganismos infecciosos
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US10329608B2 (en) 2012-10-10 2019-06-25 Life Technologies Corporation Methods, systems, and computer readable media for repeat sequencing
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US8962366B2 (en) 2013-01-28 2015-02-24 Life Technologies Corporation Self-aligned well structures for low-noise chemical sensors
US8963216B2 (en) 2013-03-13 2015-02-24 Life Technologies Corporation Chemical sensor with sidewall spacer sensor surface
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WO2014151961A1 (en) * 2013-03-14 2014-09-25 Life Technologies Corporation Matrix arrays and methods for making same
US20140296080A1 (en) 2013-03-14 2014-10-02 Life Technologies Corporation Methods, Systems, and Computer Readable Media for Evaluating Variant Likelihood
EP2972279B1 (de) 2013-03-15 2021-10-06 Life Technologies Corporation Chemischer sensor mit stetigen sensoroberflächen
WO2014149779A1 (en) 2013-03-15 2014-09-25 Life Technologies Corporation Chemical device with thin conductive element
US9835585B2 (en) 2013-03-15 2017-12-05 Life Technologies Corporation Chemical sensor with protruded sensor surface
EP2972280B1 (de) 2013-03-15 2021-09-29 Life Technologies Corporation Chemischer sensor mit stetigen sensoroberflächen
US9116117B2 (en) 2013-03-15 2015-08-25 Life Technologies Corporation Chemical sensor with sidewall sensor surface
US20140336063A1 (en) 2013-05-09 2014-11-13 Life Technologies Corporation Windowed Sequencing
US10458942B2 (en) 2013-06-10 2019-10-29 Life Technologies Corporation Chemical sensor array having multiple sensors per well
CN105683980B (zh) 2013-10-04 2018-08-24 生命科技股份有限公司 在使用终止化学物质的测序中建立分阶段效应模型的方法和系统
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TW202024628A (zh) 2014-12-18 2020-07-01 美商生命技術公司 用於使用大規模fet陣列量測分析物之方法及設備
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CN107969138B (zh) 2015-05-14 2022-04-12 生命科技公司 条形码序列和有关系统与方法
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CN105543071A (zh) * 2015-12-10 2016-05-04 严媚 一种用于高通量基因测序的cmos isfet双模式图像化学传感器芯片
CN105758919A (zh) * 2016-03-01 2016-07-13 杭州格磊思沃科技有限公司 半导体疾病芯片的制造方法
US10619205B2 (en) 2016-05-06 2020-04-14 Life Technologies Corporation Combinatorial barcode sequences, and related systems and methods
US10724089B2 (en) 2016-10-06 2020-07-28 The Board Of Trustees Of The University Of Illinois Spatial molecular analysis of tissue
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CN108732225B (zh) * 2017-04-19 2021-07-13 中芯国际集成电路制造(上海)有限公司 离子敏感场效应晶体管及其形成方法
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Also Published As

Publication number Publication date
CN102203597A (zh) 2011-09-28
EP3650847A1 (de) 2020-05-13
WO2009158006A3 (en) 2010-05-06
WO2009158006A2 (en) 2009-12-30
EP2304420A2 (de) 2011-04-06
JP2011525990A (ja) 2011-09-29

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