EP2293918A2 - Process for the manufacture of single-dose phials for fluid products of the medical, pharmaceutical, cosmetic type or the like, and a phial thus obtainable - Google Patents

Process for the manufacture of single-dose phials for fluid products of the medical, pharmaceutical, cosmetic type or the like, and a phial thus obtainable

Info

Publication number
EP2293918A2
EP2293918A2 EP09754187A EP09754187A EP2293918A2 EP 2293918 A2 EP2293918 A2 EP 2293918A2 EP 09754187 A EP09754187 A EP 09754187A EP 09754187 A EP09754187 A EP 09754187A EP 2293918 A2 EP2293918 A2 EP 2293918A2
Authority
EP
European Patent Office
Prior art keywords
process according
phial
semi
outlet opening
finished product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP09754187A
Other languages
German (de)
English (en)
French (fr)
Inventor
Antonio Fontana
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lameplast SRL
Original Assignee
Lameplast SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lameplast SRL filed Critical Lameplast SRL
Publication of EP2293918A2 publication Critical patent/EP2293918A2/en
Withdrawn legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C49/00—Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor
    • B29C49/22—Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor using multilayered preforms or parisons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/06—Ampoules or carpules
    • A61J1/067—Flexible ampoules, the contents of which are expelled by squeezing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B26—HAND CUTTING TOOLS; CUTTING; SEVERING
    • B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
    • B26D3/00—Cutting work characterised by the nature of the cut made; Apparatus therefor
    • B26D3/16—Cutting rods or tubes transversely
    • B26D3/166—Trimming tube-ends
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C49/00—Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor
    • B29C49/42—Component parts, details or accessories; Auxiliary operations
    • B29C49/4273—Auxiliary operations after the blow-moulding operation not otherwise provided for
    • B29C49/4278—Cutting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D1/00—Containers having bodies formed in one piece, e.g. by casting metallic material, by moulding plastics, by blowing vitreous material, by throwing ceramic material, by moulding pulped fibrous material, by deep-drawing operations performed on sheet material
    • B65D1/09—Ampoules
    • B65D1/095—Ampoules made of flexible material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2207/00—Methods of manufacture, assembly or production
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C2791/00—Shaping characteristics in general
    • B29C2791/001—Shaping in several steps
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C2793/00—Shaping techniques involving a cutting or machining operation
    • B29C2793/0009—Cutting out
    • B29C2793/0018—Cutting out for making a hole
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C2793/00—Shaping techniques involving a cutting or machining operation
    • B29C2793/0027—Cutting off
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C2793/00—Shaping techniques involving a cutting or machining operation
    • B29C2793/0045—Perforating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C2793/00—Shaping techniques involving a cutting or machining operation
    • B29C2793/009—Shaping techniques involving a cutting or machining operation after shaping
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
    • B29C48/001—Combinations of extrusion moulding with other shaping operations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
    • B29C48/001—Combinations of extrusion moulding with other shaping operations
    • B29C48/0022—Combinations of extrusion moulding with other shaping operations combined with cutting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
    • B29C48/03—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor characterised by the shape of the extruded material at extrusion
    • B29C48/12—Articles with an irregular circumference when viewed in cross-section, e.g. window profiles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
    • B29C48/16—Articles comprising two or more components, e.g. co-extruded layers
    • B29C48/18—Articles comprising two or more components, e.g. co-extruded layers the components being layers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C49/00—Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor
    • B29C49/02—Combined blow-moulding and manufacture of the preform or the parison
    • B29C49/04—Extrusion blow-moulding
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2023/00—Use of polyalkenes or derivatives thereof as moulding material
    • B29K2023/04—Polymers of ethylene
    • B29K2023/06—PE, i.e. polyethylene
    • B29K2023/0608—PE, i.e. polyethylene characterised by its density
    • B29K2023/0625—LLDPE, i.e. linear low density polyethylene
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2023/00—Use of polyalkenes or derivatives thereof as moulding material
    • B29K2023/04—Polymers of ethylene
    • B29K2023/06—PE, i.e. polyethylene
    • B29K2023/0608—PE, i.e. polyethylene characterised by its density
    • B29K2023/0633—LDPE, i.e. low density polyethylene
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2023/00—Use of polyalkenes or derivatives thereof as moulding material
    • B29K2023/04—Polymers of ethylene
    • B29K2023/06—PE, i.e. polyethylene
    • B29K2023/0608—PE, i.e. polyethylene characterised by its density
    • B29K2023/065—HDPE, i.e. high density polyethylene
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2023/00—Use of polyalkenes or derivatives thereof as moulding material
    • B29K2023/04—Polymers of ethylene
    • B29K2023/08—Copolymers of ethylene
    • B29K2023/086—EVOH, i.e. ethylene vinyl alcohol copolymer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2023/00—Tubular articles
    • B29L2023/20—Flexible squeeze tubes, e.g. for cosmetics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/753—Medical equipment; Accessories therefor
    • B29L2031/7544—Injection needles, syringes

Definitions

  • the present invention relates to a process for the manufacture of single-dose phials for fluid products of the medical, pharmaceutical, cosmetic type or the like, and a phial thus obtainable.
  • the traditional "barrier" materials can be of both the metal and the plastic type.
  • the single-dose phials usually have a body intended to contain the fluid product that is made of aluminium and which at one extremity is welded to a dispensing spout in plastic material made separately, e.g., by injection moulding.
  • the main aim of the present invention is to provide a process for the manufacture of single-dose phials for fluid products of the medical, pharmaceutical, cosmetic type or the like, that allows manufacturing in a practical, easy and functional way single-dose phials which, once used, can be disposed of in a simple and practical way.
  • Another object of the present invention is to provide a process for the manufacture of single-dose phials for fluid products of the medical, pharmaceutical, cosmetic type or the like, that allows overcoming the mentioned drawbacks of the background art within the ambit of a simple and rational solution that is easy and effective to use and of low cost.
  • figure 1 is an exploded section view of some barrier layers superimposed the one on the other used in the process according to the invention
  • figure 2 is a section view of a first phase of the process according to the invention
  • figure 3 is a section view of a second phase of the process according to the invention
  • figure 4 is a side view of a third phase of the process according to the invention
  • figure 5 is a axonometric view of a fourth phase of the process according to the invention
  • figure 6 is a section view of a fifth phase of the process according to the invention.
  • a single-dose phial for fluid products of the medical, pharmaceutical, cosmetic type or the like obtainable with the process according to the invention, has been globally indicated by 1.
  • the walls of the single-dose phial 1 are made by means of at least a barrier layer 2, 3, 4 of plastic material in which, e.g., the barrier layer 2, 3, 4 is chosen from the list comprising: LDPE (low density polyethylene), HDPE (high density polyethylene), LLDPE (linear low density polyethylene), EVOH (ethylene vinyl alcohol) and the like.
  • the walls of the single-dose phial 1 consist in a series of barrier layers 2, 3, 4 in plastic material, superimposed the one on the other, of which an outer layer 2 in LDPE (thickness 0.1-0.2 mm), an intermediate layer 3 in EVOH (thickness 0.02-0.04 mm), and an inner layer 4 in LDPE (thickness 0.1-0.2 mm).
  • a layer of adhesive material 5 is interposed between one barrier layer 2, 3, 4 and another.
  • the process according to the invention comprises a first phase I which consists in extruding the barrier layers 2, 3, 4 through a extruder die 6 to form a first semi-finished product 7 with tubular shape having a proximal extremity 8 and a distal extremity 9, in which the adjectives proximal and distal are used with reference to the distance from the extruder die 6.
  • the second phase II of the process consists in blowing an expansion gas 10 inside the first semi-finished product through the proximal extremity 8.
  • the first semi-finished product 7 is closed inside a forming mould 11, 12 which has a first half-shell 11 and a second half-shell 12.
  • the half-shells 11, 12 are shaped so that, during the blowing, the distal extremity 9 of the first semi-finished product 7 is closed; the filling with the expansion gas 10, therefore, causes the deformation of the walls of the first semi-finished product 7 and their crushing against the inner walls of the half- shells 11, 12, leading to the formation of a second semi-finished product 13.
  • the forming mould 11, 12 is shaped so as to give the second semi-finished product 13 a substantially axial-symmetric and elongated shape along a longitudinal direction that extends between the proximal extremity 8 and the distal extremity 9; other embodiments cannot however be ruled out.
  • the second semi-finished product 13 obtained at the exit from the forming mould 11, 12, has a dispensing spout 14, obtained at the distal extremity 9, while the proximal extremity 8 of same consists in a deformed waste portion (feedhead).
  • the third phase III of the process consists in removing the proximal extremity 8 from the second semi-finished product 13 to define an open bottom 15 for the introduction of a fluid product, of the medical, pharmaceutical, cosmetic type or the like.
  • the removal phase is defined by the performance of a cutting-off operation (with cutting-off machine, circular saws or similar tools), or cutting (e.g., by laser or other cutting tools), or shearing (with shearing units or the like).
  • the process according to the invention further comprises a fourth phase IV that consists in drilling the distal extremity 9 to define an outlet opening 16 for the fluid product.
  • the outlet opening 16 is made in a substantially axial position at the extremity of the dispensing spout 14 by means of an operation of punching of the distal extremity 9 by means of a substantially pointed punching element 17.
  • the punching element 17 is first of all heated to favour the penetration of same through the second semi-finished product 13.
  • the second semi-finished product 13 appears modified to form the single-dose phial 1 having the open bottom 15, which is sealable after the filling of the phial itself with the fluid product, the dispensing spout 14 arranged on the opposite side with respect to the open bottom 15, and the outlet opening 16 obtained on the dispensing spout 14.
  • the fifth phase V of the process consists in seal capping the outlet opening 16 with a closing element 18 of the type of a cap or the like.
  • the closing element 18 comprises a cap 19 that can be fitted around the dispensing spout 14 and a shutter body 20 obtained inside the cap 19 and which can be seal fitted in the outlet opening 16.
  • This checking phase is performed by means of the carrying out of a seal test such as, e.g., a high-pressure test, a low-pressure test, a steam test, an electrical conductivity test or similar methods.
  • a seal test such as, e.g., a high-pressure test, a low-pressure test, a steam test, an electrical conductivity test or similar methods.
  • the single-dose phial 1 thus obtained can, if necessary, be blister packed and packaged in order to be subsequently introduced onto the market and distributed to consumers.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Manufacturing & Machinery (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Forests & Forestry (AREA)
  • Ceramic Engineering (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Packages (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP09754187A 2008-05-30 2009-05-25 Process for the manufacture of single-dose phials for fluid products of the medical, pharmaceutical, cosmetic type or the like, and a phial thus obtainable Withdrawn EP2293918A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000170A ITMO20080170A1 (it) 2008-05-30 2008-05-30 Procedimento per la fabbricazione di fiale monodose per prodotti fluidi di tipo medicale, farmaceutico, cosmetico o simili, e fiala cosi' ottenibile
PCT/IB2009/005706 WO2009144559A2 (en) 2008-05-30 2009-05-25 Process for the manufacture of single-dose phials for fluid products of the medical, pharmaceutical, cosmetic type or the like, and a phial thus obtainable

Publications (1)

Publication Number Publication Date
EP2293918A2 true EP2293918A2 (en) 2011-03-16

Family

ID=40302894

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09754187A Withdrawn EP2293918A2 (en) 2008-05-30 2009-05-25 Process for the manufacture of single-dose phials for fluid products of the medical, pharmaceutical, cosmetic type or the like, and a phial thus obtainable

Country Status (3)

Country Link
EP (1) EP2293918A2 (it)
IT (1) ITMO20080170A1 (it)
WO (1) WO2009144559A2 (it)

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Publication number Priority date Publication date Assignee Title
CH707854A2 (de) * 2013-03-20 2014-09-30 Alpla Werke Extrusionsblasgeformte Tube.
MX2016001625A (es) * 2013-08-12 2016-06-02 Printpack Illinois Inc Metodo para fabricar envases moldeados por soplado con capa de multiples barreras.
CN105593130B (zh) 2013-10-04 2018-10-16 西拉克集团公司 吹塑的颈缩容器
JP6710677B2 (ja) * 2015-03-30 2020-06-17 テルモ株式会社 医療用コネクタ
DE102016122061A1 (de) * 2016-11-16 2018-05-17 Schott Ag Verfahren zur Herstellung von Glasfläschchen mit geringer Delaminationsneigung unter der Einwirkung einer Spülgasströmung
US11331844B2 (en) 2018-05-25 2022-05-17 The Procter & Gamble Company Container having coordinated mold part line and longitudinal seam
US11358747B2 (en) 2019-04-29 2022-06-14 The Procter & Gamble Company Low opacity thermoformed container having longitudinal seam

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GB969453A (en) * 1962-04-26 1964-09-09 Tubed Chemicals Corp Manufacture of squeeze tube containers
AU527536B2 (en) * 1978-06-02 1983-03-10 Toyo Seikan Kaisha Ltd. Squeeze tube vessel
AR034176A1 (es) * 2000-11-08 2004-02-04 Graham Packaging Pet Tech Metodo de produccion de un envase plastico de forma en tubo comprimible, articulo intermedio para utilizacion en la formacion de un envase plastico de forma en tubo comprimible, y envase plastico de forma en tubo comprimible
TW200513254A (en) * 2003-10-07 2005-04-16 Santen Pharmaceutical Co Ltd Container manufacturing device
WO2006046647A1 (ja) * 2004-10-27 2006-05-04 Santen Pharmaceutical Co., Ltd. 液体収容容器および液体収容容器の製造方法
CA2636500A1 (en) * 2006-01-23 2007-07-26 Yoshio Oyama An ampoule usable as a syringe and a syringe unit comprising the ampoule

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Also Published As

Publication number Publication date
WO2009144559A3 (en) 2010-08-12
WO2009144559A2 (en) 2009-12-03
ITMO20080170A1 (it) 2009-11-30

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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