EP2049402A1 - Dispositif et procédé de stérilisation de récipients - Google Patents
Dispositif et procédé de stérilisation de récipientsInfo
- Publication number
- EP2049402A1 EP2049402A1 EP07786493A EP07786493A EP2049402A1 EP 2049402 A1 EP2049402 A1 EP 2049402A1 EP 07786493 A EP07786493 A EP 07786493A EP 07786493 A EP07786493 A EP 07786493A EP 2049402 A1 EP2049402 A1 EP 2049402A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- container
- sterilization
- guide
- sterilization medium
- interior
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B55/00—Preserving, protecting or purifying packages or package contents in association with packaging
- B65B55/02—Sterilising, e.g. of complete packages
- B65B55/04—Sterilising wrappers or receptacles prior to, or during, packaging
- B65B55/10—Sterilising wrappers or receptacles prior to, or during, packaging by liquids or gases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
- A61L2/186—Peroxide solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/26—Accessories or devices or components used for biocidal treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/20—Targets to be treated
- A61L2202/23—Containers, e.g. vials, bottles, syringes, mail
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/20—Targets to be treated
- A61L2202/24—Medical instruments, e.g. endoscopes, catheters, sharps
Definitions
- the invention relates to an apparatus and a method for the sterilization of containers with a guide for introducing a gas and / or vaporous sterilization medium through a container opening into the interior of a container.
- Containers such as beverage or drug bottles or cans, must be frequently sterilized prior to their filling to prevent spoilage of the product to be filled therein.
- aseptic treatment and filling systems can be done under clean room conditions, a filling of the container, whereby a subsequent sterilization of the container with its contents, eg. B. by heating, can be avoided, which may be desirable in terms of quality and / or the taste of the bottled goods.
- a liquid, gas or vaporous sterilization medium is conducted into the interior of the containers, where a sterilization reaction takes place.
- the container can still z. B. are rinsed with sterile water.
- Sterilization of the interior of the container may not be sufficient if the requirements are met in order to achieve the desired degree of sterility in the treatment and / or filling of the container.
- the outside of the container in a further treatment step, must be sterilized, for example by spraying with a liquid, gas or vapor sterilizing medium.
- the object of the invention is to provide a way to sterilize containers as simple as possible and yet in a sufficient degree for aseptic treatment and filling measure.
- the invention achieves this by means of a device for the sterilization of containers having the features of patent claim 1.
- the guide device provided for this purpose is designed in an embodiment, for example, as the container opening surrounding bell. This is open in the direction of the container bottom and coaxially surrounds the guide, which is formed for example in the form of a conduit.
- the guide directs the sterilization medium through the container interior to the vicinity of the container bottom, from where it is pressed in the direction of the container opening and thereby comes into contact with the inside of the container.
- a part of the sterilization medium exits from the container opening on the outside of the guide and is then deflected by the guide means, so that the sterilization medium in the sequence also comes into contact with the outer wall of the bottle.
- the bell can be matched to the type of container used by having a shape that follows the container outer contour with a certain constant or increasing distance.
- the guide device can also be designed as an elongate tunnel. Again, the tunnel is open in the direction of the container bottom and the bottles are moved together with the introduced guide through the tunnel. Otherwise, the sterilization proceeds as described above, wherein the sterilization medium emerging from the container opening is passed through the tunnel walls to the outer region of the container.
- the containers are picked up on one side and sterilized all around.
- the guide is introduced through the container opening in the interior of the container until it is, as described, with its opening in the vicinity of the container bottom.
- the sterilization medium is passed through this into the interior of the container, so that the sterilization reaction can begin.
- the guide in the embodiment together with the guide device, withdrawn from the container opening, so that the container is free and can leave the sterilization device.
- vaporous H 2 O 2 is used as the sterilization medium. It is introduced in a vaporous state into the interior of the container and, upon contact with the relatively cooler container surfaces, forms a condensation film in the interior of the container and on the regions of the outer wall of the container to which it has also been guided by the guide device. Following the application of the condensation film, the H 2 O 2 is activated, for example, in an activation device by supplying a specific amount of heat T, for example by using hot air and / or steam. After activation, a decomposition reaction of H 2 O 2 takes place, in the course of which different free radicals are formed, which in turn react with the germs and / or impurities present on the surfaces and thus effect the sterilization. At the end of the decomposition reaction are essentially water and some decay residues.
- FIG. 1 is a side view of the device according to the invention in a first embodiment
- Fig. 3 is a partially sectioned side view of an alternative embodiment of the invention.
- a device generally designated 1 for the sterilization of containers is shown in more detail in FIGS. 1 and 2.
- the device 1 a bell 3, which surrounds the tube 2 coaxially.
- the tube 2 is inserted during the passage of the machine from above through the container opening into the container, wherein the length of the tube 2 is dimensioned so that it lies at maximum immersion depth in the region of the container bottom.
- the tube 2 is inserted during the passage of the machine from above through the container opening into the container, wherein the length of the tube 2 is dimensioned so that it lies at maximum immersion depth in the region of the container bottom.
- the H 2 O 2 forms a condensation film due to the temperature difference between the vaporous H 2 O 2 and the container wall.
- the leaking from the container opening H 2 O 2 is redirected by the special shape of the inside of the bell 3, so that it does not easily escape into the environment, but is guided along the outer wall of the container in the region of the container opening and the container neck. Again, the H 2 O 2 forms a condensation film.
- the bell 3 Due to the design of the bell 3 can be determined to what extent should extend in the direction of the container bottom of the condensation film formed.
- the formation of the film can be assisted by adapting the shape of the bell 3 to the outer contour of the container to be sterilized, for example by designing the bell 3 so that it always follows the outer contour of the container at a constant or increasing distance.
- H 2 O 2 When using H 2 O 2 as the sterilization medium, this is activated by supplying a certain amount of heat.
- hot air or hot steam is blown into the interior or to the outside of the container or the corresponding amount of heat supplied in another known manner.
- the hot air or hot steam may be supplied through the pipe 2, whereby the bell 3 also serves to direct these media to the desired locations.
- a decomposition reaction starts, in which the H 2 O 2 decomposes with intermediate formation of free radicals. These free radicals react, inter alia, with germs and other impurities and sterilize in this way the treated areas.
- water remains with some decomposition products.
- the container can be rinsed and / or dried or brought directly for further treatment or filling.
- FIG. 1 An alternative embodiment of the invention is shown in FIG.
- the illustrated sterilization device 10 again has a tube 12 for introducing a vaporous sterilizing agent, such as H 2 O 2 , into the interior of a bottle 11 to be sterilized.
- a vaporous sterilizing agent such as H 2 O 2
- the opening of the container 11 and the upper neck area is surrounded by a guide tunnel 13, which deflects the emerging from the container opening sterilization medium and directs it to the outer wall of the bottle 11.
- the bottle 11 is moved by a transport holder 14 through the fixed guide tunnel 13, wherein the tube 12 is guided synchronously with the bottle.
- the tube 12 is inserted from above into the bottle opening until the opening of the tube 12 lies in the bottom region of the bottle 11.
- the sterilization device 10 shown in a cross-section in FIG. 3 can be designed in a linear or rotary construction, ie the bottles to be treated can be moved on a straight or a circular path.
- the condensation film resulting from the condensation of the vaporous medium is activated by supplying a quantity of heat when H 2 O 2 is used, so that, as already described, a sterilizing decomposition reaction is initiated.
- this is done by spraying the container outside with hot steam, which exits through the illustrated nozzles 15 and is introduced from a steam reservoir, not shown through the pipes 16 in the machine.
- the invention is not limited to the above embodiment, but can be modified in many ways without departing from the spirit.
- the precise shapes of the guide means are variable and adaptable to the container type and the necessary degree of sterility.
- the materials used and sterilization media can be modified depending on the purpose.
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Filling Of Jars Or Cans And Processes For Cleaning And Sealing Jars (AREA)
Abstract
L'invention concerne un dispositif et un procédé de stérilisation de récipients (11), avec un moyen directeur (2, 12) pour introduire un agent de stérilisation sous forme de gaz et/ou de vapeur à l'intérieur d'un récipient (11) par une ouverture du récipient. Afin que le récipient (11) soit stérilisé le plus simplement possible et néanmoins dans une mesure suffisante pour qu'il soit manipulé et rempli dans des conditions aseptiques, l'invention prévoit un moyen de guidage (3, 13) pour diriger l'agent de stérilisation sortant du récipient sur la paroi extérieure du récipient (11).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102006036763A DE102006036763A1 (de) | 2006-08-05 | 2006-08-05 | Vorrichtung und Verfahren zur Sterilisation von Behältern |
PCT/EP2007/006807 WO2008017410A1 (fr) | 2006-08-05 | 2007-08-01 | Dispositif et procédé de stérilisation de récipients |
Publications (1)
Publication Number | Publication Date |
---|---|
EP2049402A1 true EP2049402A1 (fr) | 2009-04-22 |
Family
ID=38608889
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP07786493A Ceased EP2049402A1 (fr) | 2006-08-05 | 2007-08-01 | Dispositif et procédé de stérilisation de récipients |
Country Status (8)
Country | Link |
---|---|
US (1) | US20090196790A1 (fr) |
EP (1) | EP2049402A1 (fr) |
JP (1) | JP2010500238A (fr) |
CN (1) | CN101500894A (fr) |
DE (1) | DE102006036763A1 (fr) |
MX (1) | MX2008016260A (fr) |
RU (1) | RU2009107783A (fr) |
WO (1) | WO2008017410A1 (fr) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102174538B (zh) | 2003-10-23 | 2013-06-19 | 奇尼塔二有限责任公司 | 检测与抗病毒感染性有关的基因oas1中的突变的方法 |
DE102007028471A1 (de) * | 2007-06-18 | 2008-12-24 | Krones Ag | Vorrichtung zum Behandeln von Gefäßen in einem Gefäßdesinfektionssystem |
WO2009009676A2 (fr) | 2007-07-11 | 2009-01-15 | Stokely-Van Camp, Inc. | Zone de stérilisation active destinée au remplissage de contenants |
FR2923802B1 (fr) | 2007-11-19 | 2012-08-31 | Sidel Participations | Dispositif de transport d'un corps creux, installation pourvue de tels dispositifs et procede de convoyage d'un corps creux solidarise a un tel dispositif. |
ES2528324T3 (es) * | 2009-07-03 | 2015-02-06 | Tetra Laval Holdings & Finance S.A. | Dispositivo y método para el tratamiento de envases por flujo gaseoso |
RU2528494C2 (ru) * | 2009-07-03 | 2014-09-20 | Тетра Лаваль Холдингз Энд Файнэнс С.А. | Способ и устройство для поддержания барьера для газового потока между двумя объемами канала |
DE102011015344A1 (de) * | 2011-03-28 | 2012-10-04 | Krones Aktiengesellschaft | Verfahren und Vorrichtung zum Sterilisieren von Verpackungsmitteln |
JP6397173B2 (ja) * | 2013-10-07 | 2018-09-26 | 三菱重工機械システム株式会社 | 殺菌装置 |
EP3037379B1 (fr) * | 2014-12-22 | 2018-07-11 | Gea Procomac S.p.A. | Dispositif et procede destiné à éliminer des restes d'un agent de sterilisation |
DE102015102401B3 (de) * | 2015-02-20 | 2016-04-28 | Khs Gmbh | Verfahren sowie Behandlungsstation zum Erhitzen und Sterilisieren von KEGs, insbesondere von Mehrweg-KEGs |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1979001074A1 (fr) * | 1978-05-16 | 1979-12-13 | Ex Cell O Corp | Procede et moyens d'application d'un bactericide dans un recipient pour sa sterilisation |
DE3150035A1 (de) * | 1981-12-17 | 1983-06-23 | Robert Bosch Gmbh, 7000 Stuttgart | Vorrichtung zum sterilisieren von verpackungsbehaeltern |
DE3809855A1 (de) * | 1987-08-01 | 1989-02-09 | Seitz Enzinger Noll Masch | Verfahren zum aseptischen bzw. sterilen abfuellen von fluessigem fuellgut in behaelter sowie vorrichtung zum durchfuehren dieses verfahrens |
US20040208781A1 (en) * | 2001-09-05 | 2004-10-21 | Makoto Hayashi | Article sterilizing methods and sterilizing device |
-
2006
- 2006-08-05 DE DE102006036763A patent/DE102006036763A1/de not_active Withdrawn
-
2007
- 2007-08-01 WO PCT/EP2007/006807 patent/WO2008017410A1/fr active Application Filing
- 2007-08-01 MX MX2008016260A patent/MX2008016260A/es not_active Application Discontinuation
- 2007-08-01 JP JP2009523180A patent/JP2010500238A/ja not_active Withdrawn
- 2007-08-01 EP EP07786493A patent/EP2049402A1/fr not_active Ceased
- 2007-08-01 CN CNA2007800293513A patent/CN101500894A/zh active Pending
- 2007-08-01 RU RU2009107783/21A patent/RU2009107783A/ru not_active Application Discontinuation
-
2009
- 2009-02-04 US US12/365,493 patent/US20090196790A1/en not_active Abandoned
Non-Patent Citations (1)
Title |
---|
See references of WO2008017410A1 * |
Also Published As
Publication number | Publication date |
---|---|
RU2009107783A (ru) | 2010-09-10 |
JP2010500238A (ja) | 2010-01-07 |
US20090196790A1 (en) | 2009-08-06 |
MX2008016260A (es) | 2009-01-16 |
CN101500894A (zh) | 2009-08-05 |
DE102006036763A1 (de) | 2008-02-07 |
WO2008017410A1 (fr) | 2008-02-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20090305 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL BA HR MK RS |
|
17Q | First examination report despatched |
Effective date: 20090605 |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: KHS GMBH |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED |
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18R | Application refused |
Effective date: 20100809 |