EP1904110A4 - Ciblage de cellules présentant un microarn d'expression modifiée - Google Patents
Ciblage de cellules présentant un microarn d'expression modifiéeInfo
- Publication number
- EP1904110A4 EP1904110A4 EP06741167A EP06741167A EP1904110A4 EP 1904110 A4 EP1904110 A4 EP 1904110A4 EP 06741167 A EP06741167 A EP 06741167A EP 06741167 A EP06741167 A EP 06741167A EP 1904110 A4 EP1904110 A4 EP 1904110A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- microrna expression
- targeting cells
- altered microrna
- altered
- targeting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
- A61K48/0058—Nucleic acids adapted for tissue specific expression, e.g. having tissue specific promoters as part of a contruct
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/111—General methods applicable to biologically active non-coding nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/635—Externally inducible repressor mediated regulation of gene expression, e.g. tetR inducible by tetracyline
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
- C12N2310/141—MicroRNAs, miRNAs
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/50—Methods for regulating/modulating their activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/10—Plasmid DNA
- C12N2800/106—Plasmid DNA for vertebrates
- C12N2800/107—Plasmid DNA for vertebrates for mammalian
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/50—Vector systems having a special element relevant for transcription regulating RNA stability, not being an intron, e.g. poly A signal
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
- C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/10—Vectors comprising a special translation-regulating system regulates levels of translation
- C12N2840/102—Vectors comprising a special translation-regulating system regulates levels of translation inhibiting translation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Plant Pathology (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP11161737A EP2377559A1 (fr) | 2005-06-03 | 2006-06-02 | Ciblage de cellules dotées d'une expression de microARN |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68754705P | 2005-06-03 | 2005-06-03 | |
PCT/AU2006/000750 WO2006128245A1 (fr) | 2005-06-03 | 2006-06-02 | Ciblage de cellules presentant un microarn d'expression modifiee |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1904110A1 EP1904110A1 (fr) | 2008-04-02 |
EP1904110A4 true EP1904110A4 (fr) | 2009-02-11 |
Family
ID=37481150
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP11161737A Withdrawn EP2377559A1 (fr) | 2005-06-03 | 2006-06-02 | Ciblage de cellules dotées d'une expression de microARN |
EP06741167A Withdrawn EP1904110A4 (fr) | 2005-06-03 | 2006-06-02 | Ciblage de cellules présentant un microarn d'expression modifiée |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP11161737A Withdrawn EP2377559A1 (fr) | 2005-06-03 | 2006-06-02 | Ciblage de cellules dotées d'une expression de microARN |
Country Status (5)
Country | Link |
---|---|
EP (2) | EP2377559A1 (fr) |
JP (1) | JP2008541737A (fr) |
AU (1) | AU2006254732A1 (fr) |
CA (1) | CA2610702A1 (fr) |
WO (1) | WO2006128245A1 (fr) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1771563A2 (fr) | 2004-05-28 | 2007-04-11 | Ambion, Inc. | PROCEDES ET COMPOSITIONS FAISANT INTERVENIR DES MOLECULES DE Micro-ARN |
ES2534304T3 (es) | 2004-11-12 | 2015-04-21 | Asuragen, Inc. | Procedimientos y composiciones que implican miARN y moléculas inhibidoras de miARN |
WO2008015662A1 (fr) † | 2006-08-04 | 2008-02-07 | Dublin City University | Procédé d'obtention de produits biologiques recombinants |
JP2010504350A (ja) * | 2006-09-19 | 2010-02-12 | アシュラジェン インコーポレイテッド | 治療的介入の標的としての、miR−200によって調節される遺伝子および経路 |
CA2663962A1 (fr) * | 2006-09-19 | 2008-03-27 | Asuragen, Inc. | Genes regules mir-15, mir-26, mir -31,mir -145, mir-147, mir-188, mir-215, mir-216 mir-331, mmu-mir-292-3p et voies de signalisation utiles comme cibles dans une intervention therapeutique |
EP2487240B1 (fr) * | 2006-09-19 | 2016-11-16 | Interpace Diagnostics, LLC | Micro ARN différemment exprimés dans des maladies pancréatiques et leurs utilisations |
EP2094848A2 (fr) * | 2006-09-19 | 2009-09-02 | Asuragen, INC. | GÈNES ET TRAJETS RÉGULÉS PAR miR-143 COMME CIBLES D'INTERVENTION THÉRAPEUTIQUE |
EP2111408A4 (fr) * | 2007-01-17 | 2010-02-03 | Univ Johns Hopkins | Compositions et procédés comprenant des microarn pour traiter une néoplasie |
EP2136846A4 (fr) * | 2007-03-26 | 2011-04-13 | Crc For Asthma And Airways Ltd | Cibles therapeutique et molecules |
CA2683314A1 (fr) * | 2007-04-11 | 2008-10-23 | Merck & Co., Inc. | Molecules d'acide nucleique isolees correspondant au micro arn 145 (mirna-145) et utilisation de ces dernieres dans le traitement du cancer du colon |
AU2008240673A1 (en) * | 2007-04-19 | 2008-10-30 | Katholieke Universiteit Leuven, K.U. Leuven R & D | Oligonucleotide compositions for the treatment of Alzheimer's disease |
CN101883576B (zh) | 2007-07-31 | 2015-08-19 | 得克萨斯系统大学董事会 | 调控纤维化的微小rna家族及其用途 |
WO2009036332A1 (fr) | 2007-09-14 | 2009-03-19 | Asuragen, Inc. | Microarn exprimés de manière différentielle dans le cancer du col de l'utérus et leurs utilisations |
JP2009100687A (ja) * | 2007-10-24 | 2009-05-14 | Chiba Univ | microRNA発現プロファイリングに基づく膀胱癌の検出方法 |
EP2280078B1 (fr) * | 2008-03-27 | 2016-05-18 | Kuroda, Masahiko | Marqueur pour la détermination du cancer du sein, méthode d'essai, et kit d'essai |
EP2112235A1 (fr) * | 2008-04-24 | 2009-10-28 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Compositions et procédés pour le profilage de l'expression de microARN du carcinome du nasopharynx |
EP2990487A1 (fr) | 2008-05-08 | 2016-03-02 | Asuragen, INC. | Compositions et procédés relatifs à la modulation de miarn de néovascularisation ou angiogenèse |
US20110098346A1 (en) * | 2008-05-19 | 2011-04-28 | Agency For Science, Technology And Research | Nucleic acid molecule and method of targeting gene expression to gliomas |
WO2010075101A2 (fr) * | 2008-12-15 | 2010-07-01 | Dcb-Usa, Llc | Traitement d'une infection par un picornavirus par ciblage du micro-arn mir-141 |
SG175839A1 (en) * | 2009-04-30 | 2011-12-29 | San Raffaele Centro Fond | Gene vector |
WO2010135714A2 (fr) * | 2009-05-22 | 2010-11-25 | The Methodist Hospital Research Institute | Méthodes de modulation de l'expression des adipocytes utilisant des compositions de micro-arn |
EP2341145A1 (fr) * | 2009-12-30 | 2011-07-06 | febit holding GmbH | Empreinte ARNm dans le diagnostic de maladies |
WO2011111715A1 (fr) * | 2010-03-09 | 2011-09-15 | 協和発酵キリン株式会社 | Acide nucléique apte à réguler le cycle cellulaire |
WO2011112732A2 (fr) | 2010-03-12 | 2011-09-15 | The Brigham And Women's Hospital, Inc. | Procédés de traitement de troubles inflammatoire vasculaires |
US9006201B2 (en) | 2010-07-08 | 2015-04-14 | Takeda Pharmaceutical Company Limited | Prophylactic or therapeutic agent for diabetes |
AU2012212105A1 (en) | 2011-02-03 | 2013-09-12 | Mirna Therapeutics, Inc. | Synthetic mimics of miR-124 |
WO2013040251A2 (fr) | 2011-09-13 | 2013-03-21 | Asurgen, Inc. | Méthodes et compositions incluant mir-135b, permettant de faire la distinction entre un cancer du pancréas et une maladie pancréatique bénigne |
ITRM20110685A1 (it) | 2011-12-23 | 2013-06-24 | Internat Ct For Genetic En Gineering And | Microrna per la rigenerazione cardiaca attraverso l induzione della proliferazione dei miociti cardiaci |
PL2922554T3 (pl) | 2012-11-26 | 2022-06-20 | Modernatx, Inc. | Na zmodyfikowany na końcach |
JP5704576B2 (ja) * | 2012-12-28 | 2015-04-22 | 国立大学法人 千葉大学 | microRNA発現プロファイリングに基づく膀胱癌の検出方法 |
JP5704575B2 (ja) * | 2012-12-28 | 2015-04-22 | 国立大学法人 千葉大学 | microRNA発現プロファイリングに基づく膀胱癌の検出方法 |
JP5812361B2 (ja) * | 2013-07-11 | 2015-11-11 | 国立研究開発法人医薬基盤・健康・栄養研究所 | 遺伝子発現制御機構を含む新規Adベクター |
CN104120128B (zh) * | 2014-07-02 | 2016-04-20 | 重庆贝羿生物科技有限公司 | 一种用于促进vhl基因表达的分离的核苷酸分子和促进剂及其制备 |
CN104726500B (zh) * | 2015-03-12 | 2017-09-12 | 中国人民解放军第二军医大学 | MicroRNA26b‑3p抑制剂在制备人脐带来源间充质干细胞中的应用 |
CA3001003A1 (fr) * | 2015-10-05 | 2017-04-13 | Modernatx, Inc. | Procedes d'administration therapeutique de medicaments a base d'acide ribonucleique messager |
US11293065B2 (en) | 2016-03-14 | 2022-04-05 | Aelan Cell Technologies, Inc. | Compositions and methods for the quality control of stem cell preparations |
KR20190053179A (ko) * | 2016-07-26 | 2019-05-17 | 센티 바이오사이언시스, 인코포레이티드 | 유전자 지우개들 |
JP7130639B2 (ja) | 2016-11-01 | 2022-09-05 | ザ・リサーチ・ファウンデーション・フォー・ザ・ステイト・ユニヴァーシティ・オブ・ニューヨーク | 5-ハロウラシル修飾マイクロrna及びがんの処置におけるその使用 |
GB201805287D0 (en) * | 2018-03-29 | 2018-05-16 | Univ Edinburgh | Haematoietic stem cell treatment |
MX2020013667A (es) | 2018-06-14 | 2021-03-02 | Ovid Therapeutics Inc | Uso de mir-92a o mir-145 en el tratamiento del sindrome de angelman. |
CN112301033B (zh) * | 2020-11-24 | 2021-11-19 | 南通大学 | miR-30a-5p及其在促进神经再生和修复周围神经损伤方面的应用 |
CN113750111A (zh) * | 2021-09-23 | 2021-12-07 | 清华大学深圳国际研究生院 | 一种miRNA-15A用于治疗高表达KIF3B肿瘤中的用途 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005078096A2 (fr) * | 2004-02-09 | 2005-08-25 | University Of Massachusetts | Oligonucleotides fonctionnels doubles utilises pour reprimer l'expression d'un gene mutant |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005054494A2 (fr) * | 2003-11-26 | 2005-06-16 | University Of Massachusetts | Inhibition sequence-specifique de la fonction du petit arn |
EP1713938A2 (fr) * | 2004-02-09 | 2006-10-25 | Thomas Jefferson University | Diagnostic et traitement de cancers a l'aide de microarn present dans ou au voisinage de caracteristiques chromosomiennes liees aux cancers |
EP1784501B1 (fr) * | 2004-05-14 | 2015-11-18 | Rosetta Genomics Ltd | Arnmi viraux ou associés aux virus et leur utilisation |
CN101031658A (zh) * | 2004-05-26 | 2007-09-05 | 罗塞塔金诺米克斯有限公司 | 病毒和病毒相关mirna及其用途 |
US10000757B2 (en) * | 2005-05-27 | 2018-06-19 | Ospedale San Raffaele S.R.L. | Gene vector |
-
2006
- 2006-06-02 AU AU2006254732A patent/AU2006254732A1/en not_active Abandoned
- 2006-06-02 EP EP11161737A patent/EP2377559A1/fr not_active Withdrawn
- 2006-06-02 JP JP2008513869A patent/JP2008541737A/ja active Pending
- 2006-06-02 WO PCT/AU2006/000750 patent/WO2006128245A1/fr active Application Filing
- 2006-06-02 CA CA002610702A patent/CA2610702A1/fr not_active Abandoned
- 2006-06-02 EP EP06741167A patent/EP1904110A4/fr not_active Withdrawn
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005078096A2 (fr) * | 2004-02-09 | 2005-08-25 | University Of Massachusetts | Oligonucleotides fonctionnels doubles utilises pour reprimer l'expression d'un gene mutant |
Non-Patent Citations (3)
Title |
---|
JOHN BINO ET AL: "Human MicroRNA targets.", PLOS BIOLOGY NOV 2004, vol. 2, no. 11, November 2004 (2004-11-01), pages e363, XP009109996, ISSN: 1545-7885 * |
MANSFIELD JENNIFER H ET AL: "MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression", NATURE GENETICS, NATURE PUBLISHING GROUP, NEW YORK, US, vol. 36, no. 10, 1 October 2004 (2004-10-01), pages 1079 - 1083, XP002394622, ISSN: 1061-4036 * |
See also references of WO2006128245A1 * |
Also Published As
Publication number | Publication date |
---|---|
JP2008541737A (ja) | 2008-11-27 |
WO2006128245A1 (fr) | 2006-12-07 |
EP2377559A1 (fr) | 2011-10-19 |
EP1904110A1 (fr) | 2008-04-02 |
CA2610702A1 (fr) | 2006-12-07 |
AU2006254732A1 (en) | 2006-12-07 |
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Owner name: SOUTHERN ADELAIDE HEALTH SERVICE - FLINDERS MEDICA |
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