EP1841424A4 - SYNTHESIS OF ARYL PYRROLIDONES - Google Patents

SYNTHESIS OF ARYL PYRROLIDONES

Info

Publication number
EP1841424A4
EP1841424A4 EP06719887A EP06719887A EP1841424A4 EP 1841424 A4 EP1841424 A4 EP 1841424A4 EP 06719887 A EP06719887 A EP 06719887A EP 06719887 A EP06719887 A EP 06719887A EP 1841424 A4 EP1841424 A4 EP 1841424A4
Authority
EP
European Patent Office
Prior art keywords
synthesis
pyrrolidones
aryl
aryl pyrrolidones
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06719887A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP1841424A2 (en
Inventor
Yun He
David Woodmanse
Ha-Soon Choi
Zhicheng Wang
Baogen Wu
Nguyen Truc Ngoc
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IRM LLC
Original Assignee
IRM LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IRM LLC filed Critical IRM LLC
Publication of EP1841424A2 publication Critical patent/EP1841424A2/en
Publication of EP1841424A4 publication Critical patent/EP1841424A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EP06719887A 2005-01-28 2006-01-30 SYNTHESIS OF ARYL PYRROLIDONES Withdrawn EP1841424A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64803905P 2005-01-28 2005-01-28
PCT/US2006/003240 WO2006081562A2 (en) 2005-01-28 2006-01-30 Synthesis of aryl pyrrolidones

Publications (2)

Publication Number Publication Date
EP1841424A2 EP1841424A2 (en) 2007-10-10
EP1841424A4 true EP1841424A4 (en) 2010-01-27

Family

ID=36741151

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06719887A Withdrawn EP1841424A4 (en) 2005-01-28 2006-01-30 SYNTHESIS OF ARYL PYRROLIDONES

Country Status (10)

Country Link
EP (1) EP1841424A4 (enExample)
JP (1) JP2008528625A (enExample)
KR (1) KR100890696B1 (enExample)
CN (1) CN101111246A (enExample)
AU (1) AU2006209241B2 (enExample)
BR (1) BRPI0607294A2 (enExample)
CA (1) CA2593816A1 (enExample)
MX (1) MX2007008974A (enExample)
RU (1) RU2007132260A (enExample)
WO (1) WO2006081562A2 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013526542A (ja) 2010-05-12 2013-06-24 アッヴィ・インコーポレイテッド キナーゼのインダゾール阻害薬
CN101979378B (zh) * 2010-10-13 2012-06-27 中国科学院上海有机化学研究所 一种手性γ-内酰胺化合物的合成方法
RU2485100C1 (ru) * 2012-02-07 2013-06-20 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Пермский государственный национальный исследовательский университет" 1-арил-4-бензоил-3-гидрокси-5-метоксикарбонил-2,5-дигидро-1н-пиррол-2-оны, проявляющие анальгетическую активность, и способ их получения
AU2014357342B2 (en) 2013-12-03 2019-01-17 Fmc Corporation Pyrrolidinones as herbicides
US11589583B2 (en) 2013-12-03 2023-02-28 Fmc Corporation Pyrrolidinones herbicides
UA125012C2 (uk) 2014-07-02 2021-12-29 ЕфЕмСі КОРПОРЕЙШН Піперидинонові гербіциди
BR112017009701B1 (pt) 2014-12-08 2021-09-08 Fmc Corporation Composto e métodos de preparação de compostos
WO2016164201A1 (en) 2015-04-10 2016-10-13 E I Du Pont De Nemours And Company Substituted cyclic amides as herbicides
BR112017020094B1 (pt) 2015-04-27 2022-01-11 Fmc Corporation Composto, composições herbicidas, mistura de herbicida e método para controlar o crescimento de vegetação indesejada
RU2750293C2 (ru) 2015-05-12 2021-06-25 ЭфЭмСи Корпорейшн Арилзамещенные бициклические соединения в качестве гербицидов
CN107690426B (zh) 2015-05-29 2021-07-06 Fmc公司 作为除草剂的取代的环酰胺
RU2017142979A (ru) 2015-06-02 2019-07-15 ЭфЭмСи Корпорейшн Замещенные циклические амиды и их применение в качестве гербицидов
RU2720994C2 (ru) 2015-07-31 2020-05-15 Е.И.Дюпон Де Немур Энд Компани Новые соединения циклического n-карбоксамида, применяемые в качестве гербицидов
ES2958741T3 (es) 2016-12-21 2024-02-14 Fmc Corp Herbicidas de nitrona
UA126576C2 (uk) 2017-03-21 2022-11-02 ЕфЕмСі КОРПОРЕЙШН Гербіцидна суміш, композиція та спосіб
CN110691516B (zh) 2017-03-21 2022-10-28 Fmc公司 吡咯烷酮及其制备方法
AR111967A1 (es) 2017-05-30 2019-09-04 Fmc Corp Amidas herbicidas
AR111839A1 (es) 2017-05-30 2019-08-21 Fmc Corp Lactamas 3-sustituidas herbicidas
CN116782894A (zh) * 2020-10-06 2023-09-19 D.E.肖研究有限责任公司 作为Kv1.3钾Shaker通道阻断剂的内酰胺化合物

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3956314A (en) * 1970-07-24 1976-05-11 U.C.B., Societe Anonyme Derivatives of 2-pyrrolidinone
WO2004037784A2 (en) * 2002-10-21 2004-05-06 Irm Llc Pyrrolidones with anti-hiv activity
WO2006081554A2 (en) * 2005-01-28 2006-08-03 Irm Llc Phenyl-substituted pyrrolidones

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3058986A (en) * 1962-10-16 N-ammoalkyl-x-phenyl-x-lower alkyl-z-
US3956914A (en) * 1974-11-14 1976-05-18 The Marison Company Spin lathe
JP2002363160A (ja) * 2001-06-05 2002-12-18 Sumitomo Chem Co Ltd 光学活性４−アリール−２−ピペリジノン類の製造方法
JP4351859B2 (ja) * 2003-04-14 2009-10-28 三菱レイヨン株式会社 光学活性β−アリ−ル化合物の製造法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3956314A (en) * 1970-07-24 1976-05-11 U.C.B., Societe Anonyme Derivatives of 2-pyrrolidinone
WO2004037784A2 (en) * 2002-10-21 2004-05-06 Irm Llc Pyrrolidones with anti-hiv activity
WO2006081554A2 (en) * 2005-01-28 2006-08-03 Irm Llc Phenyl-substituted pyrrolidones

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
KEITH FAGNOU AND MARK LAUTENS: "Rhodium-catalyzed carbon-carbon bond forming reactions of organometallic compounds", CHEMICAL REVIEWS, vol. 103, no. 1, 2003, pages 169 - 196, XP002559949 *
MARK LAUTENS ET AL: "Rhodium-catalyzed Heck-type coupling of boronic acids with activated alkenes in an aqueous emulsion", SYNTHESIS, no. 12, 2004, pages 2006 - 2014, XP001205153, ISSN: 0039-7881 *
RYO SHINTANI ET AL: "Chiral norbornadienes as efficient ligands for the rhodium-catalyzed asymmetric 1,4-addition of arylboronic acids to fumaric and maleic compounds", ORGANIC LETTERS, vol. 6, no. 19, 2004, pages 3425 - 3427, XP002559905 *
TAICHI SENDA ET AL: "Rhodium-catalyzed asymmetric 1,4-addition of organoboron reagents to 5,6-dihydro-2(1H)-pyridinones. Asymmetric synthesis of 4-aryl-2-piperidinones", JOURNAL OF ORGANIC CHEMISTRY, vol. 66, no. 21, 2001, pages 6852 - 6856, XP002977097, ISSN: 0022-3263 *
TAMIO HAYASHI AND KAORI YAMASAKI: "Rhodium-catalyzed asymmetric 1,4-addition and its related asymmetric reactions", CHEMICAL REVIEWS, vol. 103, no. 8, 2003, pages 2829 - 2844, XP002559950 *

Also Published As

Publication number Publication date
KR100890696B1 (ko) 2009-03-26
AU2006209241B2 (en) 2009-10-22
RU2007132260A (ru) 2009-03-10
AU2006209241A1 (en) 2006-08-03
EP1841424A2 (en) 2007-10-10
MX2007008974A (es) 2007-09-18
CN101111246A (zh) 2008-01-23
JP2008528625A (ja) 2008-07-31
WO2006081562A3 (en) 2006-10-19
KR20070097555A (ko) 2007-10-04
CA2593816A1 (en) 2006-08-03
WO2006081562A2 (en) 2006-08-03
BRPI0607294A2 (pt) 2009-08-25

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