EP1812582A4 - PRODUCTION OF A SINGLE PROTEIN IN LIVING CELLS FACILITATED BY A MESSENGER RNA INTERFERASE - Google Patents

PRODUCTION OF A SINGLE PROTEIN IN LIVING CELLS FACILITATED BY A MESSENGER RNA INTERFERASE

Info

Publication number
EP1812582A4
EP1812582A4 EP05851377A EP05851377A EP1812582A4 EP 1812582 A4 EP1812582 A4 EP 1812582A4 EP 05851377 A EP05851377 A EP 05851377A EP 05851377 A EP05851377 A EP 05851377A EP 1812582 A4 EP1812582 A4 EP 1812582A4
Authority
EP
European Patent Office
Prior art keywords
living cells
messenger rna
protein production
single protein
cells facilitated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP05851377A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP1812582A2 (en
Inventor
Inouye Masayori
Junjie Zhang
Motoo Suzuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Medicine and Dentistry of New Jersey
Original Assignee
University of Medicine and Dentistry of New Jersey
Rutgers State University of New Jersey
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Medicine and Dentistry of New Jersey, Rutgers State University of New Jersey filed Critical University of Medicine and Dentistry of New Jersey
Publication of EP1812582A2 publication Critical patent/EP1812582A2/en
Publication of EP1812582A4 publication Critical patent/EP1812582A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases RNAses, DNAses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP05851377A 2004-11-04 2005-11-04 PRODUCTION OF A SINGLE PROTEIN IN LIVING CELLS FACILITATED BY A MESSENGER RNA INTERFERASE Withdrawn EP1812582A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62497604P 2004-11-04 2004-11-04
PCT/US2005/040107 WO2006055292A2 (en) 2004-11-04 2005-11-04 Single protein production in living cells facilitated by a messenger rna interferase

Publications (2)

Publication Number Publication Date
EP1812582A2 EP1812582A2 (en) 2007-08-01
EP1812582A4 true EP1812582A4 (en) 2013-03-20

Family

ID=36407606

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05851377A Withdrawn EP1812582A4 (en) 2004-11-04 2005-11-04 PRODUCTION OF A SINGLE PROTEIN IN LIVING CELLS FACILITATED BY A MESSENGER RNA INTERFERASE

Country Status (6)

Country Link
EP (1) EP1812582A4 (ja)
JP (1) JP5013375B2 (ja)
KR (1) KR101064783B1 (ja)
CN (1) CN101052713B (ja)
CA (1) CA2577180A1 (ja)
WO (1) WO2006055292A2 (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5122957B2 (ja) * 2005-08-16 2013-01-16 タカラバイオ株式会社 免疫不全ウイルス感染症の治療または予防のための核酸
US20110306751A1 (en) * 2008-10-04 2011-12-15 University Of Medicine And Dentistry Of New Jersey Independently Inducible System of Gene Expression
EP2848695A1 (en) 2013-09-16 2015-03-18 Inria Institut National de Recherche en Informatique et en Automatique Method for producing metabolites, peptides and recombinant proteins
CN103484471B (zh) * 2013-09-30 2015-07-08 王悦 人表皮细胞生长因子核酸序列及大肠杆菌表达载体
KR101776368B1 (ko) * 2014-10-02 2017-09-07 서울시립대학교 산학협력단 전령 ｒｎａ 나노입자 및 그 제조방법
TW202000240A (zh) * 2018-02-23 2020-01-01 日商盧卡科學股份有限公司 用於在粒線體內使蛋白質表現之核酸、封入前述核酸之脂質膜結構體及其等之用途

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004113498A2 (en) * 2003-06-13 2004-12-29 University Of Medicine And Dentistry Of New Jersey Rna interferases and methods of use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5807718A (en) * 1994-12-02 1998-09-15 The Scripps Research Institute Enzymatic DNA molecules

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004113498A2 (en) * 2003-06-13 2004-12-29 University Of Medicine And Dentistry Of New Jersey Rna interferases and methods of use thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHRISTENSEN S K ET AL: "Toxin-antitoxin Loci as Stress-response-elements: ChpAK/MazF and ChpBK Cleave Translated RNAs and are Counteracted by tmRNA", JOURNAL OF MOLECULAR BIOLOGY, ACADEMIC PRESS, UNITED KINGDOM, vol. 332, no. 4, 26 September 2003 (2003-09-26), pages 809 - 819, XP004454294, ISSN: 0022-2836, DOI: 10.1016/S0022-2836(03)00922-7 *
SUZUKI MOTOO ET AL: "Single protein production in living cells facilitated by an mRNA interferase", MOLECULAR CELL, CELL PRESS, CAMBRIDGE, MA, US, vol. 18, no. 2, 15 April 2005 (2005-04-15), pages 253 - 261, XP002545106, ISSN: 1097-2765, DOI: 10.1016/J.MOLCEL.2005.03.011 *

Also Published As

Publication number Publication date
KR20080088350A (ko) 2008-10-02
CA2577180A1 (en) 2006-05-26
KR101064783B1 (ko) 2011-09-14
JP5013375B2 (ja) 2012-08-29
EP1812582A2 (en) 2007-08-01
JP2008518623A (ja) 2008-06-05
CN101052713B (zh) 2011-01-26
CN101052713A (zh) 2007-10-10
WO2006055292A2 (en) 2006-05-26
WO2006055292A3 (en) 2006-08-03

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20070601

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Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY

RIN1 Information on inventor provided before grant (corrected)

Inventor name: SUZUKI, MOTOO

Inventor name: ZHANG, JUNJIE

Inventor name: MASAYORI, INOUYE

DAX Request for extension of the european patent (deleted)
RIN1 Information on inventor provided before grant (corrected)

Inventor name: MASAYORI, INOUYE

Inventor name: SUZUKI, MOTOO

Inventor name: ZHANG, JUNJIE

RIN1 Information on inventor provided before grant (corrected)

Inventor name: SUZUKI, MOTOO

Inventor name: MASAYORI, INOUYE

Inventor name: ZHANG, JUNJIE

A4 Supplementary search report drawn up and despatched

Effective date: 20130214

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