EP1807502A1 - Vorrichtung zum schütteln von medien - Google Patents
Vorrichtung zum schütteln von medienInfo
- Publication number
- EP1807502A1 EP1807502A1 EP05806644A EP05806644A EP1807502A1 EP 1807502 A1 EP1807502 A1 EP 1807502A1 EP 05806644 A EP05806644 A EP 05806644A EP 05806644 A EP05806644 A EP 05806644A EP 1807502 A1 EP1807502 A1 EP 1807502A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- tray
- sensor
- interface
- sensors
- sensor electronics
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000033001 locomotion Effects 0.000 claims description 20
- 238000004891 communication Methods 0.000 claims description 17
- 238000005516 engineering process Methods 0.000 claims description 6
- 230000003287 optical effect Effects 0.000 claims description 5
- 238000005259 measurement Methods 0.000 claims description 4
- 239000000523 sample Substances 0.000 claims description 3
- 230000001939 inductive effect Effects 0.000 claims description 2
- 238000000034 method Methods 0.000 claims 1
- 238000013019 agitation Methods 0.000 abstract 1
- 238000000855 fermentation Methods 0.000 description 2
- 230000004151 fermentation Effects 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000000691 measurement method Methods 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 238000011165 process development Methods 0.000 description 1
- 238000009420 retrofitting Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
- B01F31/20—Mixing the contents of independent containers, e.g. test tubes
- B01F31/22—Mixing the contents of independent containers, e.g. test tubes with supporting means moving in a horizontal plane, e.g. describing an orbital path for moving the containers about an axis which intersects the receptacle axis at an angle
Definitions
- the invention relates to a device for shaking media, which are arranged on a tray, consisting of a housing with a shaking mechanism, via which the tray is set in shaking movements, and at least one sensor connected to a sensor electronics unit having a sensor.
- laboratory shakers are used for this purpose.
- the laboratory shakers have a substantially horizontal tray on which the medium to be examined, for example in a shake flask, is located.
- the tray is thereby offset by a shaking mechanism arranged in a housing in a circular motion, a longitudinal movement or in a tilting movement.
- sensors are used.
- sensor electronics In addition to the increasing need to equip each shake flask on a tray with sensors or a sensor for sizes such as oxygen content or pH value, in order to collect data for process development here, more and more sensors with the associated cabling, sensor electronics have to be placed on the tray and data lines are housed.
- a shaker for biological fermentation is known.
- the sensors or measuring heads are arranged separately from the tray, so that the tray moves relative to the measuring heads.
- this is only possible by non-contact, optical measurement methods and separates the arrangement of sensors on the tray or on or in a shake flask.
- Object of the present invention is therefore to provide a device for shaking media that monitor a metrological monitoring of arranged on a shelf, especially in shake flasks held in motion by arranged on the tray sensors and thereby mechanical problems such Cable break of test leads for measured value processing to avoid.
- the sensor electronics are separated from the control unit and arranged on the tray, there are no movement problems with connecting cables to the sensors between sensor and sensor electronics, since the sensor electronics compared to the sensors none Subjected relative movement.
- a plurality of sensors are arranged on the tray and a central data bus is provided on the tray via which the communication between sensors and a central interface on the tray using the sensor electronics, the central interface wirelessly with a stationary interface, for example, on the housing communicates. Due to the central data bus, it is possible to wirelessly carry out the communication between the sensors and the stationary control unit via only one central interface on the shelf and via the stationary interface corresponding thereto.
- the central interface to a signal transmitter whose signals are received by a signal receiver of the fixed interface.
- the central interface to a communication receiver, which receives signals from a communication transmitter of the fixed interface. Signal receiver and communication transmitter of the fixed interface are connected to the control unit via a data line.
- the control unit has a microprocessor for processing the measured data and for controlling.
- the control unit can also be formed by a computer.
- collected and processed by the sensor electronics measurement signals of the sensors via the central Data bus directed to the central interface can be done by using radio frequencies over the known RFID (Radio Frequency Identification) technology. But it is also a wireless communication via the well-known Bluetooth technology possible.
- RFID Radio Frequency Identification
- the media are in shake flasks arranged on the tray.
- a wireless sensor adjacent to the shaking flask is provided.
- the wireless sensor can be designed as an optical sensor. It is also possible to form a sensor as a probe which can be arranged in the shaker piston with a wire connection to the sensor electronics.
- the sensor electronics and / or mechanics can be further accommodated spatially in the tray.
- the underside of the tray can be designed so that it has the dimensions and breakpoints of commercial Schüttler trays, so that an easy installation and retrofitting of laboratory shakers is possible.
- the surface of the tray can be equipped with the usual threaded hole grids, so that usual holders or coasters for shake flasks can be installed.
- the energy supply of the sensors and the sensor electronics takes place wirelessly on the tray.
- This has the advantage that even with the energy or power supply no problems with moving cables occur.
- a power supply to data lines much less sensitive to interference due to interruptions responded and the power supply only two moving cables necessary In principle, a wired connection could also be used.
- a stationary energy transmitter is provided on the housing and an energy receiver is provided on the tray.
- the energy could be transmitted inductively or through an RFID connection.
- a generator which is driven by the movement of the tray.
- Figure 1 A schematic representation of an apparatus for shaking media
- Figure 2 is a block diagram of a device for shaking media.
- a device 1 for shaking media essentially consists of a housing 2, a tray 3, sensors 4, 5, a sensor electronics 6 and a control unit 7.
- the housing 2 in this case has a shaking mechanism, not shown, which displaces the tray 3 in shaking movements.
- the shaking motion may be a circular movement, a horizontal or vertical longitudinal movement, a tilting movement or a combination of movements.
- the tray 3 has wireless sensors 4, which are formed for example as optical sensors and the shaker piston 8 are arranged adjacent, and wired sensors 5 on.
- the wired sensors 5 are formed, for example, as insertable into the shaker 8 probes.
- the sensors 4, 5 are connected to the sensor electronics 6, which is integrated in the tray 3. Measurement signals from the sensors 4, 5 are collected by the respectively assigned sensor electronics 6, processed and forwarded via a central data bus 10 to a central interface 11 likewise arranged on the tray 3. From the central interface 11 is a wireless communication with a fixed interface 12, which is arranged on the housing 2 in the example.
- the communication between the central interface 11 and fixed interface 12 takes place in the example according to the RFID (Radio Frequency Identification) technology. It enables fast and automatic data acquisition via radio waves, for example with the help of transponders and corresponding reading and transmitting devices.
- the communication between central interface and stationary Interface can also be done by radio according to the well-known Bluetooth interface standard.
- the fixed interface 12 is connected to the control unit 7 via a wire connection.
- the control unit 7 can also be designed as a separate PC. From the control unit 7 in a corresponding, reverse direction control signals to the sensor electronics 6 and the sensors 4, 5 are sent.
- the central interface 11 has a signal transmitter 13 whose signals are received by a signal receiver 14 of the stationary interface 12.
- the central interface 11 further comprises a communication receiver 15 receiving signals from a communication transmitter 16 of the fixed interface 12.
- the energy supply of the sensors 4, 5 and the sensor electronics 6 takes place wirelessly via a housing 2 fixedly arranged energy transmitter 17 and a tray
- the energy supply or energy transfer can via an RFID
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Arrangements For Transmission Of Measured Signals (AREA)
- Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
- Toys (AREA)
- Supporting Of Heads In Record-Carrier Devices (AREA)
Description
Claims
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102004052156A DE102004052156B4 (de) | 2004-10-26 | 2004-10-26 | Vorrichtung zum Schütteln von Medien |
PCT/EP2005/011166 WO2006045477A1 (de) | 2004-10-26 | 2005-10-18 | Vorrichtung zum schütteln von medien |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1807502A1 true EP1807502A1 (de) | 2007-07-18 |
EP1807502B1 EP1807502B1 (de) | 2008-02-06 |
Family
ID=35515647
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP05806644A Active EP1807502B1 (de) | 2004-10-26 | 2005-10-18 | Vorrichtung zum schütteln von medien |
Country Status (5)
Country | Link |
---|---|
US (1) | US8186870B2 (de) |
EP (1) | EP1807502B1 (de) |
AT (1) | ATE385514T1 (de) |
DE (2) | DE102004052156B4 (de) |
WO (1) | WO2006045477A1 (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102008010780B3 (de) | 2008-02-25 | 2009-10-15 | Sartorius Stedim Biotech Gmbh | Inkubator mit Schüttelvorrichtung |
US7898495B2 (en) | 2008-03-26 | 2011-03-01 | Millipore Corporation | Antenna gasket for process housing |
US8501119B2 (en) | 2008-03-26 | 2013-08-06 | Emd Millipore Corporation | Contactless power solution for low power sensors in bioprocess environments |
DE102010019232B4 (de) * | 2010-05-03 | 2013-06-27 | Eppendorf Ag | Kondensatvermeidungshaube |
US10638886B2 (en) * | 2013-03-15 | 2020-05-05 | Vita-Mix Management Corporation | Powered blending container |
US9511334B2 (en) | 2013-08-29 | 2016-12-06 | Burrell Scientific LLC | Clamp for a fluid container and method of use thereof |
CN107281974A (zh) | 2016-04-13 | 2017-10-24 | 维他拌管理有限公司 | 用于搅拌系统的辅助冷却风扇 |
US11266271B2 (en) | 2016-12-08 | 2022-03-08 | Vita-Mix Management Corporation | Motor magnetic interference ring |
CN113318666A (zh) * | 2021-05-28 | 2021-08-31 | 广州国睿科学仪器有限公司 | 一种多联分体式搅拌器 |
Family Cites Families (35)
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US2662752A (en) * | 1950-05-23 | 1953-12-15 | Miller James Franklin | Emulsifying apparatus |
US3138370A (en) * | 1963-03-04 | 1964-06-23 | Thermolyne Corp | Magnetic stirring device |
US3356346A (en) * | 1966-01-03 | 1967-12-05 | Landsberger Kurt | Test tube stirring support |
US3503592A (en) * | 1968-09-18 | 1970-03-31 | George R Taylor Sr | Liquid agitator |
US3601372A (en) * | 1969-05-20 | 1971-08-24 | New Brunswick Scientific Co | Incubator shaker apparatus |
US3780992A (en) * | 1972-07-17 | 1973-12-25 | Department Of Health Education | Vibrating pipette probe mixer |
US3997272A (en) * | 1975-12-15 | 1976-12-14 | Varian Associates | Magnetic stirrer improvement |
JPS55102399A (en) * | 1979-01-31 | 1980-08-05 | Ootake Seisakusho:Kk | Method and apparatus for measuring growth of microbial in rotary shaking culture |
US5052812A (en) * | 1990-11-19 | 1991-10-01 | New Brunswick Scientific Co., Inc. | Bath shaker |
GB2277043B (en) * | 1993-04-13 | 1996-10-30 | David John Fletcher | Orbital shaking attachment |
US6057773A (en) * | 1994-02-25 | 2000-05-02 | Shukla; Ashok K. | Unanchored sensor for fluid characteristics |
GB9408263D0 (en) * | 1994-04-26 | 1994-06-15 | Fletcher David J | Shaker attachment |
US5577837A (en) * | 1995-05-19 | 1996-11-26 | Forma Scientific, Inc. | Temperature controlled HEPA-filtered console shaker |
US5564826A (en) * | 1995-09-27 | 1996-10-15 | Robbins Scientific Corporation | Reciprocating bath shaker |
WO1998032838A1 (en) * | 1997-01-23 | 1998-07-30 | Fraeva, Tatiyana Grigorievna | Shaker |
DE19915611A1 (de) * | 1999-04-07 | 2000-11-16 | Augustinus Bader | Rollhalterung |
US6484079B2 (en) * | 2000-04-28 | 2002-11-19 | Rmc Industries Corporation | Methods and systems for remotely monitoring sensor data in delivery vehicles |
US20040050836A1 (en) * | 2000-09-29 | 2004-03-18 | Nesbitt Geoffrey John | Assembly of an integrated vessel transporter and at least one reaction vessel and integrated vessel transporter for transporting a chemical substance |
EP1243315A1 (de) * | 2001-03-22 | 2002-09-25 | Avantium International B.V. | Rührer und Verfahren zum Messen eines Parameters des zu rührenden Mediums |
WO2002101000A2 (de) * | 2001-06-11 | 2002-12-19 | Grohmann Engineering Gmbh | Schüttelmaschine und fermentieranlage |
DE10151271B4 (de) * | 2001-10-17 | 2010-01-07 | Sartorius Stedim Biotech Gmbh | Verfahren zur Durchführung von Integritätstests von Filterlementen |
DE10151269B4 (de) * | 2001-10-17 | 2005-08-25 | Sartorius Ag | Verfahren zum Überwachen der Integrität von Filtrationsanlagen |
US7860680B2 (en) * | 2002-03-07 | 2010-12-28 | Microstrain, Inc. | Robotic system for powering and interrogating sensors |
KR100466439B1 (ko) * | 2002-03-14 | 2005-01-15 | 주식회사 드림바이오스 | 호기성 퇴비화조내 온도.함수율.산소의 연속식자동측정.감시 및 제어장치 |
CN103169454B (zh) * | 2002-04-22 | 2015-11-18 | 马尔西奥·马克·阿布雷乌 | 用于测量生物学参数的装置 |
US6958693B2 (en) * | 2002-05-24 | 2005-10-25 | Procter & Gamble Company | Sensor device and methods for using same |
US6808304B2 (en) * | 2002-08-27 | 2004-10-26 | Dade Behring Inc. | Method for mixing liquid samples using a linear oscillation stroke |
US6991766B2 (en) * | 2003-07-18 | 2006-01-31 | Boehringer Ingelheim Pharmaceuticals, Inc. | Apparatus for automated synthesis |
US20050063247A1 (en) * | 2003-09-22 | 2005-03-24 | Krause Richard James | Biobag undulating mixing system |
US7270472B2 (en) * | 2005-02-23 | 2007-09-18 | Bose Corporation | Resonant shaking |
DE102006001642B4 (de) * | 2006-01-11 | 2008-02-21 | Sartorius Biotech Gmbh | Sauerstoffsensor und Messverfahren |
DE102006001623B4 (de) * | 2006-01-11 | 2009-05-07 | Sartorius Stedim Biotech Gmbh | Behälter und Verfahren zum Mischen von Medien |
DE102006005533B4 (de) * | 2006-02-07 | 2008-04-17 | Sartorius Stedim Biotech Gmbh | Verbindersystem und Verfahren zum sterilen Verbinden |
DE102006022307A1 (de) * | 2006-05-11 | 2007-11-15 | Respironics Novametrix, LLC, Wallingford | Einwegbioreaktor mit Sensoranordnung |
NZ563464A (en) * | 2007-11-14 | 2010-03-26 | Sensortec Ltd | Instrument for use in fluid with mixing element also serving to sense parameter of fluid and not physically connected to driving means |
-
2004
- 2004-10-26 DE DE102004052156A patent/DE102004052156B4/de not_active Expired - Fee Related
-
2005
- 2005-10-18 WO PCT/EP2005/011166 patent/WO2006045477A1/de active IP Right Grant
- 2005-10-18 AT AT05806644T patent/ATE385514T1/de not_active IP Right Cessation
- 2005-10-18 DE DE502005002779T patent/DE502005002779D1/de active Active
- 2005-10-18 US US11/666,210 patent/US8186870B2/en active Active
- 2005-10-18 EP EP05806644A patent/EP1807502B1/de active Active
Non-Patent Citations (1)
Title |
---|
See references of WO2006045477A1 * |
Also Published As
Publication number | Publication date |
---|---|
US20090225626A1 (en) | 2009-09-10 |
DE102004052156B4 (de) | 2007-02-08 |
ATE385514T1 (de) | 2008-02-15 |
DE502005002779D1 (de) | 2008-03-20 |
DE102004052156A1 (de) | 2006-05-04 |
EP1807502B1 (de) | 2008-02-06 |
WO2006045477A1 (de) | 2006-05-04 |
US8186870B2 (en) | 2012-05-29 |
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Inventor name: GOREN, LEN Inventor name: OBERMANN, STEFAN Inventor name: BAUMFALK, REINHARD Inventor name: CLAPP, KENNETH, P. Inventor name: SCHMELIG, CHRISTIAN |
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