EP1807502A1 - Dispositif pour agiter des agents - Google Patents

Dispositif pour agiter des agents

Info

Publication number
EP1807502A1
EP1807502A1 EP05806644A EP05806644A EP1807502A1 EP 1807502 A1 EP1807502 A1 EP 1807502A1 EP 05806644 A EP05806644 A EP 05806644A EP 05806644 A EP05806644 A EP 05806644A EP 1807502 A1 EP1807502 A1 EP 1807502A1
Authority
EP
European Patent Office
Prior art keywords
tray
sensor
interface
sensors
sensor electronics
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP05806644A
Other languages
German (de)
English (en)
Other versions
EP1807502B1 (fr
Inventor
Reinhard Baumfalk
Stefan Obermann
Christian Schmelig
Len Goren
Kenneth P. Clapp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sartorius Stedim Biotech GmbH
Original Assignee
Sartorius AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sartorius AG filed Critical Sartorius AG
Publication of EP1807502A1 publication Critical patent/EP1807502A1/fr
Application granted granted Critical
Publication of EP1807502B1 publication Critical patent/EP1807502B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/20—Mixing the contents of independent containers, e.g. test tubes
    • B01F31/22—Mixing the contents of independent containers, e.g. test tubes with supporting means moving in a horizontal plane, e.g. describing an orbital path for moving the containers about an axis which intersects the receptacle axis at an angle

Definitions

  • the invention relates to a device for shaking media, which are arranged on a tray, consisting of a housing with a shaking mechanism, via which the tray is set in shaking movements, and at least one sensor connected to a sensor electronics unit having a sensor.
  • laboratory shakers are used for this purpose.
  • the laboratory shakers have a substantially horizontal tray on which the medium to be examined, for example in a shake flask, is located.
  • the tray is thereby offset by a shaking mechanism arranged in a housing in a circular motion, a longitudinal movement or in a tilting movement.
  • sensors are used.
  • sensor electronics In addition to the increasing need to equip each shake flask on a tray with sensors or a sensor for sizes such as oxygen content or pH value, in order to collect data for process development here, more and more sensors with the associated cabling, sensor electronics have to be placed on the tray and data lines are housed.
  • a shaker for biological fermentation is known.
  • the sensors or measuring heads are arranged separately from the tray, so that the tray moves relative to the measuring heads.
  • this is only possible by non-contact, optical measurement methods and separates the arrangement of sensors on the tray or on or in a shake flask.
  • Object of the present invention is therefore to provide a device for shaking media that monitor a metrological monitoring of arranged on a shelf, especially in shake flasks held in motion by arranged on the tray sensors and thereby mechanical problems such Cable break of test leads for measured value processing to avoid.
  • the sensor electronics are separated from the control unit and arranged on the tray, there are no movement problems with connecting cables to the sensors between sensor and sensor electronics, since the sensor electronics compared to the sensors none Subjected relative movement.
  • a plurality of sensors are arranged on the tray and a central data bus is provided on the tray via which the communication between sensors and a central interface on the tray using the sensor electronics, the central interface wirelessly with a stationary interface, for example, on the housing communicates. Due to the central data bus, it is possible to wirelessly carry out the communication between the sensors and the stationary control unit via only one central interface on the shelf and via the stationary interface corresponding thereto.
  • the central interface to a signal transmitter whose signals are received by a signal receiver of the fixed interface.
  • the central interface to a communication receiver, which receives signals from a communication transmitter of the fixed interface. Signal receiver and communication transmitter of the fixed interface are connected to the control unit via a data line.
  • the control unit has a microprocessor for processing the measured data and for controlling.
  • the control unit can also be formed by a computer.
  • collected and processed by the sensor electronics measurement signals of the sensors via the central Data bus directed to the central interface can be done by using radio frequencies over the known RFID (Radio Frequency Identification) technology. But it is also a wireless communication via the well-known Bluetooth technology possible.
  • RFID Radio Frequency Identification
  • the media are in shake flasks arranged on the tray.
  • a wireless sensor adjacent to the shaking flask is provided.
  • the wireless sensor can be designed as an optical sensor. It is also possible to form a sensor as a probe which can be arranged in the shaker piston with a wire connection to the sensor electronics.
  • the sensor electronics and / or mechanics can be further accommodated spatially in the tray.
  • the underside of the tray can be designed so that it has the dimensions and breakpoints of commercial Schüttler trays, so that an easy installation and retrofitting of laboratory shakers is possible.
  • the surface of the tray can be equipped with the usual threaded hole grids, so that usual holders or coasters for shake flasks can be installed.
  • the energy supply of the sensors and the sensor electronics takes place wirelessly on the tray.
  • This has the advantage that even with the energy or power supply no problems with moving cables occur.
  • a power supply to data lines much less sensitive to interference due to interruptions responded and the power supply only two moving cables necessary In principle, a wired connection could also be used.
  • a stationary energy transmitter is provided on the housing and an energy receiver is provided on the tray.
  • the energy could be transmitted inductively or through an RFID connection.
  • a generator which is driven by the movement of the tray.
  • Figure 1 A schematic representation of an apparatus for shaking media
  • Figure 2 is a block diagram of a device for shaking media.
  • a device 1 for shaking media essentially consists of a housing 2, a tray 3, sensors 4, 5, a sensor electronics 6 and a control unit 7.
  • the housing 2 in this case has a shaking mechanism, not shown, which displaces the tray 3 in shaking movements.
  • the shaking motion may be a circular movement, a horizontal or vertical longitudinal movement, a tilting movement or a combination of movements.
  • the tray 3 has wireless sensors 4, which are formed for example as optical sensors and the shaker piston 8 are arranged adjacent, and wired sensors 5 on.
  • the wired sensors 5 are formed, for example, as insertable into the shaker 8 probes.
  • the sensors 4, 5 are connected to the sensor electronics 6, which is integrated in the tray 3. Measurement signals from the sensors 4, 5 are collected by the respectively assigned sensor electronics 6, processed and forwarded via a central data bus 10 to a central interface 11 likewise arranged on the tray 3. From the central interface 11 is a wireless communication with a fixed interface 12, which is arranged on the housing 2 in the example.
  • the communication between the central interface 11 and fixed interface 12 takes place in the example according to the RFID (Radio Frequency Identification) technology. It enables fast and automatic data acquisition via radio waves, for example with the help of transponders and corresponding reading and transmitting devices.
  • the communication between central interface and stationary Interface can also be done by radio according to the well-known Bluetooth interface standard.
  • the fixed interface 12 is connected to the control unit 7 via a wire connection.
  • the control unit 7 can also be designed as a separate PC. From the control unit 7 in a corresponding, reverse direction control signals to the sensor electronics 6 and the sensors 4, 5 are sent.
  • the central interface 11 has a signal transmitter 13 whose signals are received by a signal receiver 14 of the stationary interface 12.
  • the central interface 11 further comprises a communication receiver 15 receiving signals from a communication transmitter 16 of the fixed interface 12.
  • the energy supply of the sensors 4, 5 and the sensor electronics 6 takes place wirelessly via a housing 2 fixedly arranged energy transmitter 17 and a tray
  • the energy supply or energy transfer can via an RFID

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Arrangements For Transmission Of Measured Signals (AREA)
  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
  • Toys (AREA)
  • Supporting Of Heads In Record-Carrier Devices (AREA)
EP05806644A 2004-10-26 2005-10-18 Dispositif pour agiter des agents Active EP1807502B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004052156A DE102004052156B4 (de) 2004-10-26 2004-10-26 Vorrichtung zum Schütteln von Medien
PCT/EP2005/011166 WO2006045477A1 (fr) 2004-10-26 2005-10-18 Dispositif pour agiter des agents

Publications (2)

Publication Number Publication Date
EP1807502A1 true EP1807502A1 (fr) 2007-07-18
EP1807502B1 EP1807502B1 (fr) 2008-02-06

Family

ID=35515647

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05806644A Active EP1807502B1 (fr) 2004-10-26 2005-10-18 Dispositif pour agiter des agents

Country Status (5)

Country Link
US (1) US8186870B2 (fr)
EP (1) EP1807502B1 (fr)
AT (1) ATE385514T1 (fr)
DE (2) DE102004052156B4 (fr)
WO (1) WO2006045477A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102008010780B3 (de) 2008-02-25 2009-10-15 Sartorius Stedim Biotech Gmbh Inkubator mit Schüttelvorrichtung
US8501119B2 (en) 2008-03-26 2013-08-06 Emd Millipore Corporation Contactless power solution for low power sensors in bioprocess environments
US7898495B2 (en) 2008-03-26 2011-03-01 Millipore Corporation Antenna gasket for process housing
DE102010019232B4 (de) * 2010-05-03 2013-06-27 Eppendorf Ag Kondensatvermeidungshaube
EP2969162B1 (fr) * 2013-03-15 2024-01-24 Vita-Mix Management Corporation Récipient de mélange alimenté
US9511334B2 (en) 2013-08-29 2016-12-06 Burrell Scientific LLC Clamp for a fluid container and method of use thereof
EP3251566A3 (fr) 2016-04-13 2018-03-07 Vita-Mix Management Corporation Ventilateur de refroidissement auxiliaire pour un système de mélange
US11266271B2 (en) 2016-12-08 2022-03-08 Vita-Mix Management Corporation Motor magnetic interference ring
CN113318666A (zh) * 2021-05-28 2021-08-31 广州国睿科学仪器有限公司 一种多联分体式搅拌器

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US3356346A (en) * 1966-01-03 1967-12-05 Landsberger Kurt Test tube stirring support
US3503592A (en) * 1968-09-18 1970-03-31 George R Taylor Sr Liquid agitator
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US3780992A (en) * 1972-07-17 1973-12-25 Department Of Health Education Vibrating pipette probe mixer
US3997272A (en) * 1975-12-15 1976-12-14 Varian Associates Magnetic stirrer improvement
JPS55102399A (en) * 1979-01-31 1980-08-05 Ootake Seisakusho:Kk Method and apparatus for measuring growth of microbial in rotary shaking culture
US5052812A (en) * 1990-11-19 1991-10-01 New Brunswick Scientific Co., Inc. Bath shaker
GB2277043B (en) * 1993-04-13 1996-10-30 David John Fletcher Orbital shaking attachment
US6057773A (en) * 1994-02-25 2000-05-02 Shukla; Ashok K. Unanchored sensor for fluid characteristics
GB9408263D0 (en) * 1994-04-26 1994-06-15 Fletcher David J Shaker attachment
US5577837A (en) * 1995-05-19 1996-11-26 Forma Scientific, Inc. Temperature controlled HEPA-filtered console shaker
US5564826A (en) * 1995-09-27 1996-10-15 Robbins Scientific Corporation Reciprocating bath shaker
WO1998032838A1 (fr) 1997-01-23 1998-07-30 Fraeva, Tatiyana Grigorievna Agitateur-secoueur
DE19915611A1 (de) * 1999-04-07 2000-11-16 Augustinus Bader Rollhalterung
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AU2002211074A1 (en) * 2000-09-29 2002-04-08 Avantium International B.V. Assembly of an integrated vessel transporter and at least one reaction vessel for transporting a chemical substance
EP1243315A1 (fr) * 2001-03-22 2002-09-25 Avantium International B.V. Agitateur et procédé de mesurer un paramètre du milieu à agiter
WO2002101000A2 (fr) * 2001-06-11 2002-12-19 Grohmann Engineering Gmbh Secoueur et installation de fermentation
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Also Published As

Publication number Publication date
ATE385514T1 (de) 2008-02-15
DE102004052156B4 (de) 2007-02-08
DE502005002779D1 (de) 2008-03-20
US20090225626A1 (en) 2009-09-10
WO2006045477A1 (fr) 2006-05-04
EP1807502B1 (fr) 2008-02-06
DE102004052156A1 (de) 2006-05-04
US8186870B2 (en) 2012-05-29

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