EP1750513A4 - Verwendung von gpcr54-liganden zur behandlung von unfruchtbarkeit - Google Patents
Verwendung von gpcr54-liganden zur behandlung von unfruchtbarkeitInfo
- Publication number
- EP1750513A4 EP1750513A4 EP05804783A EP05804783A EP1750513A4 EP 1750513 A4 EP1750513 A4 EP 1750513A4 EP 05804783 A EP05804783 A EP 05804783A EP 05804783 A EP05804783 A EP 05804783A EP 1750513 A4 EP1750513 A4 EP 1750513A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- gpcr54
- infertility
- ligands
- treatment
- gpcr54 ligands
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Endocrinology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Reproductive Health (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Marine Sciences & Fisheries (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US56475604P | 2004-04-23 | 2004-04-23 | |
PCT/US2005/013339 WO2005117939A2 (en) | 2004-04-23 | 2005-04-19 | Use of gpcr54 ligands for the treatment of infertility |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1750513A2 EP1750513A2 (de) | 2007-02-14 |
EP1750513A4 true EP1750513A4 (de) | 2009-07-22 |
Family
ID=35463344
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP05804783A Withdrawn EP1750513A4 (de) | 2004-04-23 | 2005-04-19 | Verwendung von gpcr54-liganden zur behandlung von unfruchtbarkeit |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1750513A4 (de) |
JP (1) | JP2007533748A (de) |
AU (1) | AU2005249373A1 (de) |
CA (1) | CA2562676A1 (de) |
IL (1) | IL178795A0 (de) |
NO (1) | NO20065297L (de) |
WO (1) | WO2005117939A2 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2571420A1 (en) | 2004-06-25 | 2006-01-05 | Takeda Pharmaceutical Company Limited | Metastin derivatives and use thereof |
US8404643B2 (en) | 2005-12-22 | 2013-03-26 | Takeda Pharmaceutical Company Limited | Metastin derivatives and use thereof |
JO3048B1 (ar) | 2006-10-25 | 2016-09-05 | Takeda Pharmaceuticals Co | مشتقات متاستين واستخدامها |
RU2010114039A (ru) * | 2007-09-11 | 2011-10-20 | Мондобайотек Лабораториз Аг (Li) | Применение октреотида в качестве терапевтического средства |
GB0719592D0 (en) | 2007-10-08 | 2007-11-14 | Medical Res Council | Compound, use and method |
LT2314609T (lt) * | 2008-07-30 | 2017-04-10 | Takeda Pharmaceutical Company Limited | Metastino darinys ir jo panaudojimas |
WO2010033240A2 (en) | 2008-09-19 | 2010-03-25 | Nektar Therapeutics | Carbohydrate-based drug delivery polymers and conjugates thereof |
WO2010033224A1 (en) * | 2008-09-19 | 2010-03-25 | Nektar Therapeutics | Polymer conjugates of kiss1 peptides |
US9127038B2 (en) | 2011-08-04 | 2015-09-08 | Merck Sharp & Dohme Corp. | Kisspeptide-pentasaccharide conjugates |
WO2013142408A1 (en) * | 2012-03-20 | 2013-09-26 | Monell Chemical Senses Center | Method of modifying fertility |
FR3001455B1 (fr) * | 2013-01-31 | 2017-10-06 | Agronomique Inst Nat Rech | Composes agonistes du recepteur kiss1r et leur utilisation pour induire l'ovulation chez les mammiferes |
TW201605907A (zh) * | 2014-08-12 | 2016-02-16 | 國立臺灣大學 | 一種調控精子授精能力短鏈胜肽之提高體外人工授精成功率之用途 |
TWI778979B (zh) * | 2016-09-30 | 2022-10-01 | 瑞士商麥歐文科學有限公司 | 治療女性不孕症之方法 |
CN109125307B (zh) * | 2018-09-03 | 2021-05-07 | 河南牧翔动物药业有限公司 | 一种克罗米酚-多肽复合物、药物制剂及其制备方法和应用 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004063221A1 (ja) * | 2002-12-26 | 2004-07-29 | Takeda Pharmaceutical Company Limited | メタスチン誘導体およびその用途 |
WO2004080479A1 (ja) * | 2003-03-12 | 2004-09-23 | Takeda Pharmaceutical Company Limited | 性腺機能改善剤 |
-
2005
- 2005-04-19 WO PCT/US2005/013339 patent/WO2005117939A2/en active Application Filing
- 2005-04-19 CA CA002562676A patent/CA2562676A1/en not_active Abandoned
- 2005-04-19 JP JP2007509576A patent/JP2007533748A/ja not_active Withdrawn
- 2005-04-19 EP EP05804783A patent/EP1750513A4/de not_active Withdrawn
- 2005-04-19 AU AU2005249373A patent/AU2005249373A1/en not_active Abandoned
-
2006
- 2006-10-22 IL IL178795A patent/IL178795A0/en unknown
- 2006-11-17 NO NO20065297A patent/NO20065297L/no not_active Application Discontinuation
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004063221A1 (ja) * | 2002-12-26 | 2004-07-29 | Takeda Pharmaceutical Company Limited | メタスチン誘導体およびその用途 |
WO2004080479A1 (ja) * | 2003-03-12 | 2004-09-23 | Takeda Pharmaceutical Company Limited | 性腺機能改善剤 |
Non-Patent Citations (7)
Title |
---|
DE ROUX NICOLAS ET AL: "Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 100, no. 19, 16 September 2003 (2003-09-16), pages 10972 - 10976, XP002531374, ISSN: 0027-8424 * |
FUNES S ET AL: "The KiSS-1 receptor GPR54 is essential for the development of the murine reproductive system", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 312, no. 4, 26 December 2003 (2003-12-26), pages 1357 - 1363, XP004476427, ISSN: 0006-291X * |
GOTTSCH M L ET AL: "A ROLE FOR KISSPEPTINS IN THE REGULATION OF GONADOTROPIN SECRETION IN THE MOUSE", ENDOCRINOLOGY, BALTIMORE, MD, US, vol. 145, no. 9, 24 June 2004 (2004-06-24), pages 4073 - 4077, XP009052892, ISSN: 0013-7227 * |
KOTANI M ET AL: "The Metastasis Suppressor Gene KiSS-1 Encodes Kisspeptins, the Natural Ligands of the Orphan G Protein-coupled Receptor GPR54", JOURNAL OF BIOLOGICAL CHEMISTRY 20010914 AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY INC. US, vol. 276, no. 37, 14 September 2001 (2001-09-14), pages 34631 - 34636, XP002531375 * |
MESSAGER SOPHIE ET AL: "Kisspeptin directly stimulates gonadotropin-releasing hormone release via G protein-coupled receptor 54", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 102, no. 5, 1 February 2005 (2005-02-01), pages 1761 - 1766, XP002531376, ISSN: 0027-8424 * |
NAVARRO V M ET AL: "Effects of KiSS-1 Peptide, the Natural Ligand of GPR54, on Follicle-Stimulating Hormone Secretion in the Rat", ENDOCRINOLOGY, BALTIMORE, MD, US, vol. 146, no. 4, 1 April 2005 (2005-04-01), pages 1689 - 1697, XP008091360, ISSN: 0013-7227 * |
SEMINARA S B ET AL: "The GPR54 gene as a regulator of puberty", NEW ENGLAND JOURNAL OF MEDICINE, THE, MASSACHUSETTS MEDICAL SOCIETY, WALTHAM, MA, US, vol. 349, no. 17, 23 October 2003 (2003-10-23), pages 1614 - 1627, XP009021628, ISSN: 0028-4793 * |
Also Published As
Publication number | Publication date |
---|---|
WO2005117939A9 (en) | 2006-04-20 |
AU2005249373A1 (en) | 2005-12-15 |
NO20065297L (no) | 2006-11-17 |
WO2005117939A2 (en) | 2005-12-15 |
IL178795A0 (en) | 2007-03-08 |
CA2562676A1 (en) | 2005-12-15 |
WO2005117939A3 (en) | 2006-06-01 |
EP1750513A2 (de) | 2007-02-14 |
JP2007533748A (ja) | 2007-11-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20061115 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL BA HR LV MK YU |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: LABORATOIRES SERONO SA |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A01N 37/18 20060101ALI20071214BHEP Ipc: A01N 61/00 20060101ALI20071214BHEP Ipc: A61K 38/17 20060101AFI20071214BHEP |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20090623 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20090922 |