FR3001455B1 - Composes agonistes du recepteur kiss1r et leur utilisation pour induire l'ovulation chez les mammiferes - Google Patents

Composes agonistes du recepteur kiss1r et leur utilisation pour induire l'ovulation chez les mammiferes

Info

Publication number
FR3001455B1
FR3001455B1 FR1350858A FR1350858A FR3001455B1 FR 3001455 B1 FR3001455 B1 FR 3001455B1 FR 1350858 A FR1350858 A FR 1350858A FR 1350858 A FR1350858 A FR 1350858A FR 3001455 B1 FR3001455 B1 FR 3001455B1
Authority
FR
France
Prior art keywords
kiss1r
mammals
receptor
agonist compounds
inducing ovulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1350858A
Other languages
English (en)
Other versions
FR3001455A1 (fr
Inventor
Massimiliano Beltramo
Vincent Aucagne
Alain Caraty
Agnes Delmas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Institut National de Recherche pour lAgriculture lAlimentation et lEnvironnement
Original Assignee
Centre National de la Recherche Scientifique CNRS
Institut National de la Recherche Agronomique INRA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, Institut National de la Recherche Agronomique INRA filed Critical Centre National de la Recherche Scientifique CNRS
Priority to FR1350858A priority Critical patent/FR3001455B1/fr
Priority to EP14702555.5A priority patent/EP2951200A1/fr
Priority to PCT/EP2014/051886 priority patent/WO2014118318A1/fr
Priority to BR112015018283A priority patent/BR112015018283A2/pt
Priority to US14/765,251 priority patent/US9884891B2/en
Publication of FR3001455A1 publication Critical patent/FR3001455A1/fr
Application granted granted Critical
Publication of FR3001455B1 publication Critical patent/FR3001455B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07Tetrapeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02Linear peptides containing at least one abnormal peptide link
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR1350858A 2013-01-31 2013-01-31 Composes agonistes du recepteur kiss1r et leur utilisation pour induire l'ovulation chez les mammiferes Active FR3001455B1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR1350858A FR3001455B1 (fr) 2013-01-31 2013-01-31 Composes agonistes du recepteur kiss1r et leur utilisation pour induire l'ovulation chez les mammiferes
EP14702555.5A EP2951200A1 (fr) 2013-01-31 2014-01-31 Composés agonistes du récepteur kiss1 et leur utilisation pour induire l'ovulation chez les mammifères
PCT/EP2014/051886 WO2014118318A1 (fr) 2013-01-31 2014-01-31 Composés agonistes du récepteur kiss1 et leur utilisation pour induire l'ovulation chez les mammifères
BR112015018283A BR112015018283A2 (pt) 2013-01-31 2014-01-31 Composto peptídico agonista e composição farmacêutica ou veterinária
US14/765,251 US9884891B2 (en) 2013-01-31 2014-01-31 KISS1R receptor agonist compounds and use thereof for inducing ovulation in mammals

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1350858A FR3001455B1 (fr) 2013-01-31 2013-01-31 Composes agonistes du recepteur kiss1r et leur utilisation pour induire l'ovulation chez les mammiferes

Publications (2)

Publication Number Publication Date
FR3001455A1 FR3001455A1 (fr) 2014-08-01
FR3001455B1 true FR3001455B1 (fr) 2017-10-06

Family

ID=48083370

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1350858A Active FR3001455B1 (fr) 2013-01-31 2013-01-31 Composes agonistes du recepteur kiss1r et leur utilisation pour induire l'ovulation chez les mammiferes

Country Status (5)

Country Link
US (1) US9884891B2 (fr)
EP (1) EP2951200A1 (fr)
BR (1) BR112015018283A2 (fr)
FR (1) FR3001455B1 (fr)
WO (1) WO2014118318A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202334178A (zh) 2017-07-05 2023-09-01 大陸商尚華醫藥科技(江西)有限公司 一種Kiss1肽類化合物、其應用及含其的組合物
FR3128958A1 (fr) 2021-11-09 2023-05-12 Institut National De Recherche Pour L'agriculture L'alimentation Et L'environnement Composés peptidiques cycliques agonistes du récepteur kiss1r et leurs utilisations thérapeutiques

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1761680A (zh) * 2002-12-26 2006-04-19 武田药品工业株式会社 肿瘤迁移抑制素衍生物及其用途
EP1750513A4 (fr) * 2004-04-23 2009-07-22 Serono Lab Utilisation de ligands gpcr54 pour le traitement de l'infertilite
US9127038B2 (en) * 2011-08-04 2015-09-08 Merck Sharp & Dohme Corp. Kisspeptide-pentasaccharide conjugates

Also Published As

Publication number Publication date
US20150361138A1 (en) 2015-12-17
US9884891B2 (en) 2018-02-06
EP2951200A1 (fr) 2015-12-09
FR3001455A1 (fr) 2014-08-01
BR112015018283A2 (pt) 2017-08-22
WO2014118318A1 (fr) 2014-08-07

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