EP1670817A4 - USE OF A SPATIAL CONFIGURATION FOR MODULATING A PROTEIN FUNCTION - Google Patents
USE OF A SPATIAL CONFIGURATION FOR MODULATING A PROTEIN FUNCTIONInfo
- Publication number
- EP1670817A4 EP1670817A4 EP04782529A EP04782529A EP1670817A4 EP 1670817 A4 EP1670817 A4 EP 1670817A4 EP 04782529 A EP04782529 A EP 04782529A EP 04782529 A EP04782529 A EP 04782529A EP 1670817 A4 EP1670817 A4 EP 1670817A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- protein function
- spatial configuration
- modulate protein
- modulate
- spatial
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 230000004853 protein function Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/56—IFN-alpha
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Zoology (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49878503P | 2003-08-28 | 2003-08-28 | |
| US49844903P | 2003-08-28 | 2003-08-28 | |
| US49892303P | 2003-08-28 | 2003-08-28 | |
| IN280MU2004 | 2004-03-05 | ||
| IN279MU2004 | 2004-03-05 | ||
| PCT/US2004/028068 WO2005021777A2 (en) | 2003-08-28 | 2004-08-26 | Uses of spatial configuration to modulate protein function |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP1670817A2 EP1670817A2 (en) | 2006-06-21 |
| EP1670817A4 true EP1670817A4 (en) | 2008-07-16 |
Family
ID=34280101
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP04782529A Ceased EP1670817A4 (en) | 2003-08-28 | 2004-08-26 | USE OF A SPATIAL CONFIGURATION FOR MODULATING A PROTEIN FUNCTION |
| EP04809634.1A Expired - Lifetime EP1663110B1 (en) | 2003-08-28 | 2004-08-26 | Uses of interferons with altered spatial structure |
| EP10193126.9A Expired - Lifetime EP2325202B1 (en) | 2003-08-28 | 2004-08-26 | Uses of interferons with altered spatial structure |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP04809634.1A Expired - Lifetime EP1663110B1 (en) | 2003-08-28 | 2004-08-26 | Uses of interferons with altered spatial structure |
| EP10193126.9A Expired - Lifetime EP2325202B1 (en) | 2003-08-28 | 2004-08-26 | Uses of interferons with altered spatial structure |
Country Status (7)
| Country | Link |
|---|---|
| EP (3) | EP1670817A4 (enExample) |
| JP (4) | JP2007503812A (enExample) |
| KR (2) | KR20060130009A (enExample) |
| AU (2) | AU2004279350B2 (enExample) |
| CA (2) | CA2535982C (enExample) |
| PL (2) | PL1663110T3 (enExample) |
| WO (2) | WO2005034853A2 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8551469B2 (en) | 2001-02-28 | 2013-10-08 | Superlab Far East Limited | Treatment of tumors and viral diseases with recombinant interferon alpha |
| CN1245215C (zh) | 2001-02-28 | 2006-03-15 | 四川省生物工程研究中心 | 重组高效复合干扰素用作乙型肝炎表面抗原和e抗原抑制剂 |
| KR20060130009A (ko) * | 2003-08-28 | 2006-12-18 | 휴이양테크 (유에스에이), 인크. | 변경된 공간 구조를 갖는 인터페론의 용도 |
| US7585647B2 (en) | 2003-08-28 | 2009-09-08 | Guangwen Wei | Nucleic acid encoding recombinant interferon |
| WO2006076014A2 (en) * | 2004-04-30 | 2006-07-20 | Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Interferon-alpha constructs for use in the treatment of sars |
| WO2006134497A2 (en) * | 2005-03-09 | 2006-12-21 | Guangwen Wei | Uses of recombinant super-compound interferons |
| CN102101886A (zh) * | 2009-12-18 | 2011-06-22 | 四川辉阳生命工程股份有限公司 | 构象改变的重组干扰素晶体、其三维结构及应用 |
| TWI726291B (zh) | 2013-01-07 | 2021-05-01 | 英屬維爾京群島商遠東超級實驗室有限公司 | 通過干擾素的經皮和/或經粘膜給藥治療骨癌、皮膚癌、皮下癌、粘膜癌和/或粘膜下癌的方法和組合物 |
| CN111363726A (zh) * | 2018-12-26 | 2020-07-03 | 上海元宋生物技术有限公司 | 表达干扰素的溶瘤病毒及其应用 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002080958A1 (fr) * | 2001-02-28 | 2002-10-17 | Sichuan Biotechnology Research Center | Interferon supercompose de recombinaison utilise comme inhibiteur de l'antigene de surface et de l'antigene e de l'hepatite b |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6936694B1 (en) * | 1982-05-06 | 2005-08-30 | Intermune, Inc. | Manufacture and expression of large structural genes |
| US5372808A (en) | 1990-10-17 | 1994-12-13 | Amgen Inc. | Methods and compositions for the treatment of diseases with consensus interferon while reducing side effect |
| JP4709333B2 (ja) * | 1995-10-13 | 2011-06-22 | プレジデント・アンド・フエローズ・オブ・ハーバード・カレツジ | ホスホパンテテイニルトランスフェラーゼおよびその使用 |
| US5874304A (en) * | 1996-01-18 | 1999-02-23 | University Of Florida Research Foundation, Inc. | Humanized green fluorescent protein genes and methods |
| US20020043262A1 (en) * | 2000-08-22 | 2002-04-18 | Alan Langford | Spray device |
| JP2004537964A (ja) * | 2000-11-03 | 2004-12-24 | ペストカ バイオメディカル ラボラトリーズ インコーポレイテッド | インターフェロン、それに関する使用及び組成物 |
| KR20060130009A (ko) * | 2003-08-28 | 2006-12-18 | 휴이양테크 (유에스에이), 인크. | 변경된 공간 구조를 갖는 인터페론의 용도 |
-
2004
- 2004-08-26 KR KR1020067003699A patent/KR20060130009A/ko not_active Ceased
- 2004-08-26 WO PCT/US2004/028067 patent/WO2005034853A2/en not_active Ceased
- 2004-08-26 CA CA2535982A patent/CA2535982C/en not_active Expired - Lifetime
- 2004-08-26 AU AU2004279350A patent/AU2004279350B2/en not_active Expired
- 2004-08-26 PL PL04809634T patent/PL1663110T3/pl unknown
- 2004-08-26 EP EP04782529A patent/EP1670817A4/en not_active Ceased
- 2004-08-26 KR KR1020067003700A patent/KR20060133949A/ko not_active Ceased
- 2004-08-26 EP EP04809634.1A patent/EP1663110B1/en not_active Expired - Lifetime
- 2004-08-26 AU AU2004269390A patent/AU2004269390A1/en not_active Abandoned
- 2004-08-26 WO PCT/US2004/028068 patent/WO2005021777A2/en not_active Ceased
- 2004-08-26 PL PL10193126T patent/PL2325202T3/pl unknown
- 2004-08-26 JP JP2006524917A patent/JP2007503812A/ja active Pending
- 2004-08-26 CA CA002535902A patent/CA2535902A1/en not_active Abandoned
- 2004-08-26 JP JP2006524916A patent/JP5663768B2/ja not_active Expired - Fee Related
- 2004-08-26 EP EP10193126.9A patent/EP2325202B1/en not_active Expired - Lifetime
-
2011
- 2011-01-21 JP JP2011011325A patent/JP2011083292A/ja active Pending
-
2012
- 2012-05-28 JP JP2012121307A patent/JP5709800B2/ja not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002080958A1 (fr) * | 2001-02-28 | 2002-10-17 | Sichuan Biotechnology Research Center | Interferon supercompose de recombinaison utilise comme inhibiteur de l'antigene de surface et de l'antigene e de l'hepatite b |
| EP1371373A1 (en) * | 2001-02-28 | 2003-12-17 | Sichuan Biotechnology Research Center | Recombination super compound interferon used as hepatitis b surface antigen and e antigen inhibitor |
Non-Patent Citations (2)
| Title |
|---|
| AMATO I: "Silent no longer", CHEMICAL AND ENGINEERING NEWS, vol. 85, no. 4, 22 January 2007 (2007-01-22), pages 38 - 40 * |
| ANONYMOUS: "Infergen", 30 November 1998 (1998-11-30) * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005021777A3 (en) | 2005-05-12 |
| PL1663110T3 (pl) | 2014-07-31 |
| EP1663110A2 (en) | 2006-06-07 |
| JP2007503812A (ja) | 2007-03-01 |
| CA2535982A1 (en) | 2005-04-21 |
| JP2012162567A (ja) | 2012-08-30 |
| AU2004279350B2 (en) | 2011-03-10 |
| CA2535982C (en) | 2016-11-29 |
| EP1663110A4 (en) | 2008-07-16 |
| EP1670817A2 (en) | 2006-06-21 |
| EP2325202A1 (en) | 2011-05-25 |
| WO2005034853A3 (en) | 2006-04-27 |
| JP2011083292A (ja) | 2011-04-28 |
| KR20060133949A (ko) | 2006-12-27 |
| PL2325202T3 (pl) | 2015-03-31 |
| KR20060130009A (ko) | 2006-12-18 |
| CA2535902A1 (en) | 2005-03-10 |
| JP5709800B2 (ja) | 2015-04-30 |
| WO2005034853A2 (en) | 2005-04-21 |
| JP5663768B2 (ja) | 2015-02-04 |
| HK1091756A1 (en) | 2007-01-26 |
| AU2004269390A1 (en) | 2005-03-10 |
| EP1663110B1 (en) | 2013-12-18 |
| HK1158231A1 (en) | 2012-09-14 |
| WO2005021777A2 (en) | 2005-03-10 |
| EP2325202B1 (en) | 2014-10-22 |
| AU2004279350A1 (en) | 2005-04-21 |
| JP2007516214A (ja) | 2007-06-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 20060324 |
|
| AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR |
|
| DAX | Request for extension of the european patent (deleted) | ||
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 1091846 Country of ref document: HK |
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| A4 | Supplementary search report drawn up and despatched |
Effective date: 20080617 |
|
| 17Q | First examination report despatched |
Effective date: 20081127 |
|
| REG | Reference to a national code |
Ref country code: DE Ref legal event code: R003 |
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| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED |
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| 18R | Application refused |
Effective date: 20110628 |
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| REG | Reference to a national code |
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