AU2003217174A8 - Novel variants of rankl protein - Google Patents

Novel variants of rankl protein

Info

Publication number
AU2003217174A8
AU2003217174A8 AU2003217174A AU2003217174A AU2003217174A8 AU 2003217174 A8 AU2003217174 A8 AU 2003217174A8 AU 2003217174 A AU2003217174 A AU 2003217174A AU 2003217174 A AU2003217174 A AU 2003217174A AU 2003217174 A8 AU2003217174 A8 AU 2003217174A8
Authority
AU
Australia
Prior art keywords
novel variants
rankl protein
rankl
protein
variants
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003217174A
Other versions
AU2003217174A1 (en
Inventor
John R Desjarlais
Shannon Alicia Marshall
Rene S Hubert
Jamal El Yazal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Xencor Inc
Original Assignee
Xencor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xencor Inc filed Critical Xencor Inc
Publication of AU2003217174A8 publication Critical patent/AU2003217174A8/en
Publication of AU2003217174A1 publication Critical patent/AU2003217174A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2003217174A 2002-01-04 2003-01-06 Novel variants of rankl protein Abandoned AU2003217174A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US34580502P 2002-01-04 2002-01-04
US60/345,805 2002-01-04
US37345302P 2002-04-17 2002-04-17
US60/373,453 2002-04-17
US37403502P 2002-04-19 2002-04-19
US60/374,035 2002-04-19
PCT/US2003/000393 WO2003059281A2 (en) 2002-01-04 2003-01-06 Novel variants of rankl protein

Publications (2)

Publication Number Publication Date
AU2003217174A8 true AU2003217174A8 (en) 2003-07-30
AU2003217174A1 AU2003217174A1 (en) 2003-07-30

Family

ID=32096834

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003217174A Abandoned AU2003217174A1 (en) 2002-01-04 2003-01-06 Novel variants of rankl protein

Country Status (3)

Country Link
EP (1) EP1560843A4 (en)
AU (1) AU2003217174A1 (en)
WO (1) WO2003059281A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005530482A (en) 2002-01-04 2005-10-13 ゼンコー・インコーポレイテッド Dominant negative proteins and their use
US7381792B2 (en) 2002-01-04 2008-06-03 Xencor, Inc. Variants of RANKL protein
US7553930B2 (en) 2003-01-06 2009-06-30 Xencor, Inc. BAFF variants and methods thereof
DE102004014983A1 (en) * 2004-03-26 2005-10-20 Univ Stuttgart Recombinant polypeptides of the members of the TNF ligand family and their use
WO2005113598A2 (en) * 2004-05-21 2005-12-01 Xencor, Inc. Tnf super family members with altered immunogenicity
CN104059141B (en) * 2014-04-14 2017-09-12 江苏省原子医学研究所 A kind of structure of mouse RANKL mutant and its expression vector, expression and application
US9914761B2 (en) 2014-07-10 2018-03-13 Washington University Oligomers for TNF superfamily inhibition

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69740107D1 (en) * 1996-12-23 2011-03-10 Immunex Corp RECEPTOR ACTIVATOR OF NF-KAPPA B, RECEPTOR IS A MEMBER OF THE TNF RECEPTOR SUPERFAMILY
CN1318105A (en) * 1998-09-15 2001-10-17 M&E生物技术公司 Methods for down-regulating osteoprotegerin ligand activity
US7300774B1 (en) * 1999-12-09 2007-11-27 The Regents Of The University Of California Multimeric fusion proteins of the TNF superfamily ligands
WO2001025277A1 (en) * 1999-10-07 2001-04-12 Maxygen Aps Single-chain antagonist polypeptides
CA2401683A1 (en) * 2000-03-02 2001-09-07 Xencor Design and discovery of protein based tnf-.alpha. variants for the treatment of tnf-.alpha. related disorders

Also Published As

Publication number Publication date
WO2003059281A9 (en) 2004-04-22
WO2003059281A2 (en) 2003-07-24
AU2003217174A1 (en) 2003-07-30
EP1560843A2 (en) 2005-08-10
WO2003059281A3 (en) 2005-06-02
EP1560843A4 (en) 2006-09-06

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase