EP1578910A4 - Nitrilasen - Google Patents

Nitrilasen

Info

Publication number
EP1578910A4
EP1578910A4 EP02780877A EP02780877A EP1578910A4 EP 1578910 A4 EP1578910 A4 EP 1578910A4 EP 02780877 A EP02780877 A EP 02780877A EP 02780877 A EP02780877 A EP 02780877A EP 1578910 A4 EP1578910 A4 EP 1578910A4
Authority
EP
European Patent Office
Prior art keywords
nitrilases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP02780877A
Other languages
English (en)
French (fr)
Other versions
EP1578910A2 (de
Inventor
Grace Desantis
Jennifer Ann Chaplin
David Paul Weiner
Aileen Milan
Ellen Chi
Jay M Short
Mark Madden
Mark Burk
Dan Robertson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF Enzymes LLC
Original Assignee
Verenium Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Verenium Corp filed Critical Verenium Corp
Priority to EP10189100.0A priority Critical patent/EP2327765B1/de
Priority to EP20100190399 priority patent/EP2327767B1/de
Priority to EP08075753A priority patent/EP2039762A3/de
Priority to EP10190397.9A priority patent/EP2327766B1/de
Priority to EP10190401.9A priority patent/EP2319919B1/de
Publication of EP1578910A2 publication Critical patent/EP1578910A2/de
Publication of EP1578910A4 publication Critical patent/EP1578910A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/002—Nitriles (-CN)
    • C12P13/004—Cyanohydrins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Processing Of Solid Wastes (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Treatment Of Sludge (AREA)
EP02780877A 2001-06-21 2002-05-15 Nitrilasen Withdrawn EP1578910A4 (de)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP10189100.0A EP2327765B1 (de) 2001-06-21 2002-05-15 Nitralasen
EP20100190399 EP2327767B1 (de) 2001-06-21 2002-05-15 Nitralasen
EP08075753A EP2039762A3 (de) 2001-06-21 2002-05-15 Nitralasen
EP10190397.9A EP2327766B1 (de) 2001-06-21 2002-05-15 Nitralasen
EP10190401.9A EP2319919B1 (de) 2001-06-21 2002-05-15 Nitralasen

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US30018901P 2001-06-21 2001-06-21
US300189P 2001-06-21
US30900601P 2001-07-30 2001-07-30
US309006P 2001-07-30
US35133602P 2002-01-22 2002-01-22
US351336P 2002-01-22
PCT/US2002/015983 WO2003000840A2 (en) 2001-06-21 2002-05-15 Nitrilases

Related Child Applications (5)

Application Number Title Priority Date Filing Date
EP10190401.9A Division EP2319919B1 (de) 2001-06-21 2002-05-15 Nitralasen
EP08075753A Division EP2039762A3 (de) 2001-06-21 2002-05-15 Nitralasen
EP10190397.9A Division EP2327766B1 (de) 2001-06-21 2002-05-15 Nitralasen
EP20100190399 Division EP2327767B1 (de) 2001-06-21 2002-05-15 Nitralasen
EP10189100.0A Division EP2327765B1 (de) 2001-06-21 2002-05-15 Nitralasen

Publications (2)

Publication Number Publication Date
EP1578910A2 EP1578910A2 (de) 2005-09-28
EP1578910A4 true EP1578910A4 (de) 2008-06-04

Family

ID=27404717

Family Applications (6)

Application Number Title Priority Date Filing Date
EP08075753A Withdrawn EP2039762A3 (de) 2001-06-21 2002-05-15 Nitralasen
EP10190401.9A Expired - Lifetime EP2319919B1 (de) 2001-06-21 2002-05-15 Nitralasen
EP10190397.9A Expired - Lifetime EP2327766B1 (de) 2001-06-21 2002-05-15 Nitralasen
EP10189100.0A Expired - Lifetime EP2327765B1 (de) 2001-06-21 2002-05-15 Nitralasen
EP20100190399 Expired - Lifetime EP2327767B1 (de) 2001-06-21 2002-05-15 Nitralasen
EP02780877A Withdrawn EP1578910A4 (de) 2001-06-21 2002-05-15 Nitrilasen

Family Applications Before (5)

Application Number Title Priority Date Filing Date
EP08075753A Withdrawn EP2039762A3 (de) 2001-06-21 2002-05-15 Nitralasen
EP10190401.9A Expired - Lifetime EP2319919B1 (de) 2001-06-21 2002-05-15 Nitralasen
EP10190397.9A Expired - Lifetime EP2327766B1 (de) 2001-06-21 2002-05-15 Nitralasen
EP10189100.0A Expired - Lifetime EP2327765B1 (de) 2001-06-21 2002-05-15 Nitralasen
EP20100190399 Expired - Lifetime EP2327767B1 (de) 2001-06-21 2002-05-15 Nitralasen

Country Status (6)

Country Link
EP (6) EP2039762A3 (de)
JP (2) JP4405258B2 (de)
AU (2) AU2006252258B2 (de)
CA (2) CA2677781C (de)
DK (3) DK2327767T3 (de)
WO (1) WO2003000840A2 (de)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040005673A1 (en) 2001-06-29 2004-01-08 Kevin Jarrell System for manipulating nucleic acids
US7608445B1 (en) 1999-12-29 2009-10-27 Verenium Corporation Nitrilases, nucleic acids encoding them and methods for making and using them
US7300775B2 (en) 1999-12-29 2007-11-27 Verenium Corporation Methods for producing α-substituted carboxylic acids using nitrilases and strecker reagents
US20040002147A1 (en) * 1999-12-29 2004-01-01 Desantis Grace Nitrilases
US7521216B2 (en) 1999-12-29 2009-04-21 Verenium Corporation Nitrilases and methods for making and using them
US7435562B2 (en) 2000-07-21 2008-10-14 Modular Genetics, Inc. Modular vector systems
US7932064B2 (en) 2002-06-13 2011-04-26 Verenium Corporation Processes for making (R)-ethyl 4-cyano-3-hydroxybutyric acid
JP4584242B2 (ja) * 2003-02-27 2010-11-17 ビーエーエスエフ ソシエタス・ヨーロピア 改変されたニトリラーゼおよびカルボン酸の製造方法におけるその使用
AR044519A1 (es) 2003-05-02 2005-09-14 Novartis Ag Derivados de piridin-tiazol amina y de pirimidin-tiazol amina
US7198926B2 (en) 2003-05-08 2007-04-03 E. I. Du Pont De Nemours And Company Preparation of (E)- and (Z)-2-methyl-2-butenoic acids
GB0401334D0 (en) 2004-01-21 2004-02-25 Novartis Ag Organic compounds
GB0411056D0 (en) 2004-05-18 2004-06-23 Novartis Ag Organic compounds
GT200500281A (es) 2004-10-22 2006-04-24 Novartis Ag Compuestos organicos.
CA2590245A1 (en) 2004-11-11 2006-05-18 Modular Genetics, Inc. Ladder assembly and system for generating diversity
GB0426164D0 (en) 2004-11-29 2004-12-29 Novartis Ag Organic compounds
GB0507577D0 (en) 2005-04-14 2005-05-18 Novartis Ag Organic compounds
GB0510390D0 (en) 2005-05-20 2005-06-29 Novartis Ag Organic compounds
US7910708B2 (en) 2005-10-21 2011-03-22 Novartis Ag Anti-IL13 human antibodies
US20070178575A1 (en) * 2005-12-07 2007-08-02 Dunming Zhu Identification Of A Nitrilase From B. Japonicum By Rational Genome Mining And Methods Of Use
GB0601951D0 (en) 2006-01-31 2006-03-15 Novartis Ag Organic compounds
KR20080110925A (ko) 2006-04-21 2008-12-19 노파르티스 아게 아데노신 ａ２ａ 수용체 효능제로서 사용하기 위한 퓨린 유도체
CN100500832C (zh) * 2006-04-29 2009-06-17 浙江工业大学 枯草芽孢杆菌zjb-063及其应用
DE602007013441D1 (de) 2006-09-29 2011-05-05 Novartis Ag Pyrazolopyrimidine als pi3k-lipidkinasehemmer
DE602007011670D1 (de) 2007-01-10 2011-02-10 Irm Llc Verbindungen und zusammensetzungen als kanal-aktivierende proteasehemmer
WO2008106662A2 (en) * 2007-03-01 2008-09-04 Verenium Corporation Nitrilases, nucleic acids encoding them and methods for making and using them
BRPI0811562A2 (pt) 2007-05-07 2014-12-09 Novartis Ag Compostos orgânicos
EP2231280B1 (de) 2007-12-10 2016-08-10 Novartis AG Amiloride-ähnliche Pyrazine-carboxamide als ENaC Blocker
JP5165393B2 (ja) * 2008-01-10 2013-03-21 旭化成ケミカルズ株式会社 グリコール酸又はグリコール酸アンモニウムの製造方法
PL2231642T3 (pl) 2008-01-11 2014-04-30 Novartis Ag Pirymidyny jako inhibitory kinazy
US8268834B2 (en) 2008-03-19 2012-09-18 Novartis Ag Pyrazine derivatives that inhibit phosphatidylinositol 3-kinase enzyme
US8236808B2 (en) 2008-06-10 2012-08-07 Novartis Ag Pyrazine derivatives as ENAC blockers
PT2391366E (pt) 2009-01-29 2013-02-05 Novartis Ag Benzimidazoles substituídos para o tratamento de astrocitomas
US8389526B2 (en) 2009-08-07 2013-03-05 Novartis Ag 3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
EP2464649A1 (de) 2009-08-12 2012-06-20 Novartis AG Heterocyclische hydrazonverbindungen und ihre verwendung zur behandlung von krebs und entzündung
NZ598220A (en) 2009-08-17 2014-02-28 Intellikine Llc Heterocyclic compounds and uses thereof
CA2771432A1 (en) 2009-08-20 2011-02-24 Novartis Ag Heterocyclic oxime compounds
CA2777245A1 (en) 2009-10-22 2011-04-28 Vertex Pharmaceuticals Incorporated Compositions for treatment of cystic fibrosis and other chronic diseases
US8247436B2 (en) 2010-03-19 2012-08-21 Novartis Ag Pyridine and pyrazine derivative for the treatment of CF
UY33597A (es) 2010-09-09 2012-04-30 Irm Llc Compuestos y composiciones como inhibidores de la trk
WO2012034095A1 (en) 2010-09-09 2012-03-15 Irm Llc Compounds and compositions as trk inhibitors
US8372845B2 (en) 2010-09-17 2013-02-12 Novartis Ag Pyrazine derivatives as enac blockers
JP2014505088A (ja) 2011-02-10 2014-02-27 ノバルティス アーゲー Ｃ−ＭＥＴチロシンキナーゼ阻害剤としての［１，２，４］トリアゾロ［４，３−ｂ］ピリダジン化合物
JP5808826B2 (ja) 2011-02-23 2015-11-10 インテリカイン， エルエルシー 複素環化合物およびその使用
US9102671B2 (en) 2011-02-25 2015-08-11 Novartis Ag Compounds and compositions as TRK inhibitors
GB201111639D0 (en) * 2011-07-07 2011-08-24 Waterford Inst Technology A process for producing amides and acids using a nitrile-metabolising enzyme
GB201111637D0 (en) * 2011-07-07 2011-08-24 Waterford Inst Technology A process for producing amides and acids using a nitrile-metabolising enzyme
UY34305A (es) 2011-09-01 2013-04-30 Novartis Ag Derivados de heterociclos bicíclicos para el tratamiento de la hipertensión arterial pulmonar
UY34329A (es) 2011-09-15 2013-04-30 Novartis Ag Compuestos de triazolopiridina
WO2013038373A1 (en) 2011-09-16 2013-03-21 Novartis Ag Pyridine amide derivatives
WO2013038381A1 (en) 2011-09-16 2013-03-21 Novartis Ag Pyridine/pyrazine amide derivatives
ES2558457T3 (es) 2011-09-16 2016-02-04 Novartis Ag Compuestos heterocíclicos para el tratamiento de fibrosis quística
WO2013038378A1 (en) 2011-09-16 2013-03-21 Novartis Ag Pyridine amide derivatives
EP2755652B1 (de) 2011-09-16 2021-06-02 Novartis AG N-substituierte heterocyclische carboxamide
US9174994B2 (en) 2011-11-23 2015-11-03 Intellikine, Llc Enhanced treatment regimens using mTor inhibitors
CN102363775B (zh) * 2011-11-30 2014-04-02 重庆大学 一种纯化腈水解酶的方法
US8809340B2 (en) 2012-03-19 2014-08-19 Novartis Ag Crystalline form
CN104245701A (zh) 2012-04-03 2014-12-24 诺华有限公司 有酪氨酸激酶抑制剂的组合产品和其应用
US9073921B2 (en) 2013-03-01 2015-07-07 Novartis Ag Salt forms of bicyclic heterocyclic derivatives
EP2968340A4 (de) 2013-03-15 2016-08-10 Intellikine Llc Kombination von kinaseinhibitoren und verwendungen davon
TW201605450A (zh) 2013-12-03 2016-02-16 諾華公司 Ｍｄｍ２抑制劑與ＢＲＡＦ抑制劑之組合及其用途
WO2015162456A1 (en) 2014-04-24 2015-10-29 Novartis Ag Amino pyridine derivatives as phosphatidylinositol 3-kinase inhibitors
JP6433509B2 (ja) 2014-04-24 2018-12-05 ノバルティス アーゲー ホスファチジルイノシトール３−キナーゼ阻害薬としてのアミノピラジン誘導体
BR112016023967A2 (pt) 2014-04-24 2017-08-15 Novartis Ag derivados de pirazina como inibidores de fosfatidilinositol 3-cinase
WO2016011658A1 (en) 2014-07-25 2016-01-28 Novartis Ag Combination therapy
KR20170036037A (ko) 2014-07-31 2017-03-31 노파르티스 아게 조합 요법
CN104774825B (zh) * 2015-03-23 2017-11-07 浙江工业大学 腈水解酶突变体及其应用
CN108368033B (zh) * 2015-11-19 2021-05-04 Gsp作物科学有限公司 一种用于制备肟菌酯的方法
CN106854673B (zh) * 2016-12-23 2020-05-15 枣庄市杰诺生物酶有限公司 利用腈水解酶工程菌制备r-邻氯扁桃酸的方法
CN109111043B (zh) * 2018-09-16 2021-11-09 苏州渭中科技发展有限公司 一种高盐高cod废水的处理方法
CN113614242A (zh) * 2019-01-22 2021-11-05 巴斯夫欧洲公司 4-氰基苯甲酸或其盐的生产方法
US20200383960A1 (en) 2019-06-10 2020-12-10 Novartis Ag Pyridine and Pyrazine derivative for the Treatment of CF, COPD, and Bronchiectasis
JP2022547427A (ja) 2019-08-28 2022-11-14 ノバルティス アーゲー 置換１，３－フェニルヘテロアリール誘導体及び疾患の治療におけるその使用
TW202140550A (zh) 2020-01-29 2021-11-01 瑞士商諾華公司 使用抗ｔｓｌｐ抗體治療炎性或阻塞性氣道疾病之方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0780471A2 (de) * 1995-07-31 1997-06-25 Nitto Chemical Industry Co., Ltd. Neues Nitrilase-Gen

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US813998A (en) 1903-10-31 1906-02-27 Rail Joint Co Insulated rail-joint.
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
EP0528881A4 (en) 1990-04-24 1993-05-26 Stratagene Methods for phenotype creation from multiple gene populations
US5331573A (en) 1990-12-14 1994-07-19 Balaji Vitukudi N Method of design of compounds that mimic conformational features of selected peptides
JP2676568B2 (ja) 1991-06-26 1997-11-17 日東化学工業株式会社 Ｒ（−）−マンデル酸およびその誘導体の製造法
US5241087A (en) 1992-03-09 1993-08-31 Bend Research, Inc. Enantiomeric enrichment of cyanohydrins
US5631280A (en) 1995-03-29 1997-05-20 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US6030779A (en) 1995-07-18 2000-02-29 Diversa Corporation Screening for novel bioactivities
US5958672A (en) 1995-07-18 1999-09-28 Diversa Corporation Protein activity screening of clones having DNA from uncultivated microorganisms
US5965408A (en) 1996-07-09 1999-10-12 Diversa Corporation Method of DNA reassembly by interrupting synthesis
US5939250A (en) 1995-12-07 1999-08-17 Diversa Corporation Production of enzymes having desired activities by mutagenesis
DE19848129A1 (de) 1998-10-19 2000-04-20 Basf Ag Verfahren zur Herstellung chiraler Carbonsäuren aus Nitrilen mit Hilfe einer Nitrilase oder Mikroorganismen, die ein Gen für die Nitrilase enthalten
DE19929365A1 (de) 1999-06-25 2000-12-28 Basf Lynx Bioscience Ag Teilsequenzen der Gene des Primär- und Sekundärmetabolismus aus Corynebacterium glutamicum und ihr Einsatz zur mikrobiellen Herstellung von Primär- und Sekundärmetaboliten
US7300775B2 (en) * 1999-12-29 2007-11-27 Verenium Corporation Methods for producing α-substituted carboxylic acids using nitrilases and strecker reagents
AU2001228808A1 (en) 2000-01-25 2001-08-07 Kaneka Corporation Process for producing optically active carboxylic acid substituted in 2-position
AU2014284148B2 (en) 2013-06-21 2017-02-23 Bio-Rad Laboratories, Inc. Microfluidic system with fluid pickups

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0780471A2 (de) * 1995-07-31 1997-06-25 Nitto Chemical Industry Co., Ltd. Neues Nitrilase-Gen

Also Published As

Publication number Publication date
AU2010212259A1 (en) 2010-09-02
JP4405258B2 (ja) 2010-01-27
DK2327766T3 (en) 2016-03-07
EP2327765A1 (de) 2011-06-01
CA2445046A1 (en) 2003-01-03
CA2677781C (en) 2013-01-29
EP2327766B1 (de) 2015-12-02
EP2327767B1 (de) 2015-04-29
EP2039762A2 (de) 2009-03-25
AU2006252258A1 (en) 2007-01-25
CA2445046C (en) 2009-11-24
EP2319919B1 (de) 2015-08-12
AU2010212259B2 (en) 2012-11-29
JP4405528B2 (ja) 2010-01-27
JP2005509407A (ja) 2005-04-14
WO2003000840A3 (en) 2007-11-15
EP2327767A1 (de) 2011-06-01
EP2327765B1 (de) 2015-04-01
CA2677781A1 (en) 2003-01-03
DK2327765T3 (en) 2015-07-13
EP2319919A1 (de) 2011-05-11
EP2039762A3 (de) 2009-07-29
WO2003000840A2 (en) 2003-01-03
AU2006252258B2 (en) 2010-07-22
EP2327766A1 (de) 2011-06-01
EP1578910A2 (de) 2005-09-28
JP2007252382A (ja) 2007-10-04
DK2327767T3 (en) 2015-07-27

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