EP1572987A4 - Acides nucleiques et polypeptides - Google Patents

Acides nucleiques et polypeptides

Info

Publication number
EP1572987A4
EP1572987A4 EP01907128A EP01907128A EP1572987A4 EP 1572987 A4 EP1572987 A4 EP 1572987A4 EP 01907128 A EP01907128 A EP 01907128A EP 01907128 A EP01907128 A EP 01907128A EP 1572987 A4 EP1572987 A4 EP 1572987A4
Authority
EP
European Patent Office
Prior art keywords
polypeptides
nucleic acids
novel nucleic
novel
acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01907128A
Other languages
German (de)
English (en)
Other versions
EP1572987A2 (fr
Inventor
Y Tom Tang
Chenghua Liu
Radoje T Drmanac
Vinod Asundi
Ping Zhou
Chongjun Xu
Yicheng Cao
Yunquing Ma
Qing A Zhao
Dunrui Wang
Jian-Rui Wang
Jie Zhang
Feiyan Ren
Rui-Hong Chen
Zhi Wei Wang
Aidong J Xue
Yonghong Yang
Tom Wejhrman
Ryle Goodrich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nuvelo Inc
Original Assignee
Nuvelo Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/728,422 external-priority patent/US20020128187A1/en
Application filed by Nuvelo Inc filed Critical Nuvelo Inc
Publication of EP1572987A2 publication Critical patent/EP1572987A2/fr
Publication of EP1572987A4 publication Critical patent/EP1572987A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6432—Coagulation factor Xa (3.4.21.6)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21006—Coagulation factor Xa (3.4.21.6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP01907128A 2000-02-03 2001-02-05 Acides nucleiques et polypeptides Withdrawn EP1572987A4 (fr)

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
US49691400A 2000-02-03 2000-02-03
US496914 2000-02-03
US56087500A 2000-04-27 2000-04-27
US560875 2000-04-27
US59807500A 2000-06-20 2000-06-20
US598075 2000-06-20
US62032500A 2000-07-19 2000-07-19
US620325 2000-07-19
US65493600A 2000-09-01 2000-09-01
US654936 2000-09-01
US66356100A 2000-09-15 2000-09-15
US663561 2000-09-15
US69332500A 2000-10-20 2000-10-20
US693325 2000-10-20
US09/728,422 US20020128187A1 (en) 2000-02-03 2000-11-30 Novel nucleic acids and polypeptides
US728422 2000-11-30
PCT/US2001/004098 WO2001057190A2 (fr) 2000-02-03 2001-02-05 Acides nucleiques et polypeptides

Publications (2)

Publication Number Publication Date
EP1572987A2 EP1572987A2 (fr) 2005-09-14
EP1572987A4 true EP1572987A4 (fr) 2005-11-30

Family

ID=27575454

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01907128A Withdrawn EP1572987A4 (fr) 2000-02-03 2001-02-05 Acides nucleiques et polypeptides

Country Status (4)

Country Link
EP (1) EP1572987A4 (fr)
AU (1) AU2001234944A1 (fr)
CA (1) CA2399776A1 (fr)
WO (1) WO2001057190A2 (fr)

Families Citing this family (160)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020137890A1 (en) 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US7057017B2 (en) 1997-04-16 2006-06-06 Millennium Pharmaceuticals, Inc. Human dickkopf-related protein and nucleic acid molecules and uses therefor
US20030069403A1 (en) 1997-06-16 2003-04-10 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US7446181B2 (en) 1998-01-15 2008-11-04 Millennium Pharmaceuticals, Inc. Antibodies that bind human Dickkopf-1 proteins
US20030149531A1 (en) 2000-12-06 2003-08-07 Hubert Rene S. Serpentine transmembrane antigens expressed in human cancers and uses thereof
US6833438B1 (en) 1999-06-01 2004-12-21 Agensys, Inc. Serpentine transmembrane antigens expressed in human cancers and uses thereof
JP4855577B2 (ja) 1998-06-01 2012-01-18 アジェンシス，インコーポレイテッド ヒト癌で発現される新規蛇行性膜貫通抗原およびその使用
US20020172678A1 (en) 2000-06-23 2002-11-21 Napoleone Ferrara EG-VEGF nucleic acids and polypeptides and methods of use
US7264801B2 (en) 1998-08-11 2007-09-04 Genentech, Inc. EG-VEGF nucleic acids and polypeptides and method of use
US20030003507A1 (en) 1999-06-02 2003-01-02 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
US6344541B1 (en) 1998-09-25 2002-02-05 Amgen Inc. DKR polypeptides
WO2000042165A2 (fr) 1999-01-15 2000-07-20 Human Genome Sciences, Inc. Proteine specifique de la moelle osseuse
US7034132B2 (en) 2001-06-04 2006-04-25 Anderson David W Therapeutic polypeptides, nucleic acids encoding same, and methods of use
AU3774300A (en) * 1999-06-02 2000-12-18 Genentech Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
WO2001014552A1 (fr) * 1999-08-19 2001-03-01 Kurokawa, Kiyoshi Proteine meg-1
US7790861B2 (en) * 1999-09-24 2010-09-07 Philadelphia Health And Education Corporation Prostate cancer-related compositions, methods, and kits based on DNA macroarray proteomics platforms
US20020042062A1 (en) 1999-09-24 2002-04-11 Mark Stearns Prostate cancer-related compositions, methods, and kits based on DNA macroarray proteomics platforms
JP2003520031A (ja) * 1999-11-12 2003-07-02 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド ２８個のヒト分泌タンパク質
CA2395416A1 (fr) 1999-12-23 2001-06-28 Millennium Pharmaceuticals, Inc. Recepteur p2y12
AU781508B2 (en) 2000-02-11 2005-05-26 Glycozym Aps UDP-galactose: beta-D-galactose-R 4-alpha-D-galactosyltransferase, alpha4Gal-T1
JP4342069B2 (ja) * 2000-02-14 2009-10-14 生化学工業株式会社 α１，４−ガラクトース転移酵素およびそれをコードするＤＮＡ
AU6802801A (en) * 2000-03-01 2001-09-24 Genentech Inc Secreted and transmembrane polypeptides and nucleic acids encoding the same
US20020065223A1 (en) * 2000-06-16 2002-05-30 Glucksmann Maria Alexandra 33358, a novel human ankyrin family member and uses thereof
EP1698697A3 (fr) * 2000-03-24 2006-09-13 Takeda Pharmaceutical Company Limited Protéine contenant SSD, son procédé de préparation et son utilisation
JP2003530124A (ja) * 2000-04-05 2003-10-14 麒麟麦酒株式会社 新規幹細胞成長因子様ポリペプチドおよびポリヌクレオチドに関する方法および物質
EP1287124A2 (fr) * 2000-04-18 2003-03-05 Bayer Aktiengesellschaft Regulation de la serine protease semblable a l'epithine humaine
EP1280917A2 (fr) * 2000-04-26 2003-02-05 Millennium Pharmaceuticals, Inc. 21657, deshydrogenase humaine a chaine courte et ses utilisations
US20030092035A1 (en) 2000-05-04 2003-05-15 Anderson David J. Pain signaling molecules
US7510845B2 (en) 2000-05-04 2009-03-31 California Institute Of Technology Assay employing G protein-coupled receptor expressed in dorsal root ganglia
WO2001085935A2 (fr) * 2000-05-09 2001-11-15 Bayer Aktiengesellschaft Recepteur couple a une proteine g du type du gene 6 de differenciation endotheliale
EP1311688A2 (fr) * 2000-05-26 2003-05-21 Millennium Pharmaceuticals, Inc. Lipase humaine 50250 et utilisations
CA2414015A1 (fr) * 2000-06-21 2001-12-27 Incyte Genomics, Inc. Recepteurs
WO2002000861A2 (fr) * 2000-06-26 2002-01-03 Millennium Pharmaceuticals, Inc. 46619, une nouvelle synthase beta-cetoacyle et utilisations de cette derniere
AU2001281933A1 (en) * 2000-06-30 2002-01-14 Ingenium Pharmaceuticals Ag Human g protein-coupled receptor igpcr17, and uses therof
AU2001281974A1 (en) * 2000-07-13 2002-01-30 Novartis Ag Disease-associated gene
AU2001278488A1 (en) * 2000-07-25 2002-02-05 Bayer Aktiengesellschaft Regulation of human matriptase-like serine protease
EP1307557A2 (fr) 2000-08-02 2003-05-07 The Johns Hopkins University Profils d'expression de cellules endotheliales
EP1315431A1 (fr) * 2000-08-02 2003-06-04 Millennium Pharmaceuticals, Inc. Membre de la famille du facteur de liberation du gtp humain (15368) et ses utilisations
PT1313762E (pt) * 2000-08-04 2006-11-30 Ludwig Inst Cancer Res Gene supressor
EP1688496A3 (fr) * 2000-08-14 2006-08-16 Actimis Pharmaceuticals, Inc., Régulation du récepteur couple aux protéines g du type récepteur p2y1
DE60116515T2 (de) * 2000-08-14 2006-09-07 Actimis Pharmaceuticals, Inc., La Jolla Regulierung des menschlichen p2y1-ähnlichen g-protein gekoppelten rezeptors
AU2001284902A1 (en) * 2000-08-15 2002-02-25 Zymogenetics Inc. Human adenosine deaminase
WO2002016586A2 (fr) * 2000-08-21 2002-02-28 Bristol-Myers Squibb Company Nouvel homologue d'adenosine deaminase
US20030166300A1 (en) * 2000-08-30 2003-09-04 Tang Y. Tom Growth-related inflammatory and immune response protein
US20030224396A1 (en) * 2000-08-30 2003-12-04 Yonghong Xiao Regulation of human aminotransferase-like enzyme
US20040072185A1 (en) * 2000-09-15 2004-04-15 Patrizia Paterlini-Brechot Cellular genes involved in oncogenesis, products of said genes and their diagnostic and therapeutic uses
US7754435B2 (en) * 2000-09-21 2010-07-13 Philadelphia Health And Education Corporation Prostate cancer-related compositions, methods, and kits based on DNA macroarray proteomics platforms
JP2004524819A (ja) * 2000-10-04 2004-08-19 キュラジェン コーポレイション 新規なタンパク質およびこれをコードする核酸ならびにこれらのタンパク質に対する抗体
AU2002220613A1 (en) * 2000-10-11 2002-04-22 Bayer Aktiengesellschaft Regulation of human cyclophilin-type peptidyl-prolyl cis-trans isomerase
AU2001297794A1 (en) 2000-10-19 2002-12-03 Millenium Pharmaceuticals, Inc. Methods and compositions of human proteins and uses thereof.
AU2002230778A1 (en) 2000-11-03 2002-05-15 The Regents Of The University Of California Prokineticin polypeptides, related compositions and methods
US20030009017A1 (en) * 2000-11-08 2003-01-09 Leiby Kevin R. 38650, 28472, 5495, 65507, 81588 and 14354 methods and compositions of human proteins and uses thereof
AU2002229011A1 (en) * 2000-11-09 2002-05-21 Glaxo Group Limited Deaminase catalyzing the removal of the cyclopropyl moiety from abacavir-mp
US7129057B2 (en) * 2000-11-09 2006-10-31 University Of Virginia Patent Foundation Human testis specific serine/threonine kinase 3
US7312086B2 (en) 2000-12-07 2007-12-25 Bristol-Myers Squibb Company Methods of diagnosing colon adenocarcinoma using the human g-protein coupled receptor hgprbmy23
CA2433027A1 (fr) * 2000-12-21 2002-06-27 Incyte Genomics, Inc. Proteines associees a un acide nucleique
US7892730B2 (en) * 2000-12-22 2011-02-22 Sagres Discovery, Inc. Compositions and methods for cancer
US20030148920A1 (en) * 2000-12-27 2003-08-07 Steven Rosen Sulfatases and methods of use thereof
WO2002053719A2 (fr) * 2001-01-04 2002-07-11 Incyte Genomics, Inc. Proteines associees au cytosquelette
JP2005500818A (ja) * 2001-01-05 2005-01-13 インサイト・ゲノミックス・インコーポレイテッド 疾患検出および治療用分子
US6319679B1 (en) * 2001-01-26 2001-11-20 Board Of Regents, The University Of Texas System PAS kinase
US20020115136A1 (en) * 2001-02-07 2002-08-22 Gennady Merkulov Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
AU2002247716A1 (en) * 2001-02-14 2002-08-28 Axaron Bioscience Ag Proteins 7b6 and 11b4 and dna sequences encoding the same
EP1521824A2 (fr) * 2001-03-16 2005-04-13 Incyte Genomics, Inc. Acide nucleique et proteines associees
US20030044813A1 (en) * 2001-03-30 2003-03-06 Old Lloyd J. Cancer-testis antigens
US20020146795A1 (en) * 2001-04-02 2002-10-10 Shiaoping Zhu Isolated human Ras-like proteins, nucleic acid molecules encoding these human Ras-like proteins, and uses thereof
CA2443123A1 (fr) 2001-04-10 2002-10-24 Agensys, Inc. Acides nucleiques et proteines correspondantes utiles pour la detection et le traitement de divers cancers
US7927597B2 (en) * 2001-04-10 2011-04-19 Agensys, Inc. Methods to inhibit cell growth
US6962811B2 (en) 2001-05-09 2005-11-08 Millennium Pharmaceuticals, Inc. 14715, a human fringe family member nucleic acids and uses therefor
EP1403368B1 (fr) 2001-05-29 2010-09-01 Human Cell Systems, Inc. Transporteur de carnitine testiculaire et son gene
ATE483976T1 (de) 2001-06-05 2010-10-15 Exelixis Inc Gfats als modifikatoren des p53-wegs und verwendungsverfahren
EP1409549A4 (fr) * 2001-06-20 2007-10-24 Genentech Inc Compositions et procedes destines au diagnostic et au traitement de tumeurs
WO2003000874A2 (fr) * 2001-06-25 2003-01-03 Bayer Aktiengesellschaft Regulation de la proteine kinase serine/threonine humaine nek3
WO2003022995A2 (fr) 2001-09-06 2003-03-20 Agensys, Inc. Acide nucleique et proteine correspondante designes par steap-1 utiles dans le traitement et la detection du cancer
US7494646B2 (en) 2001-09-06 2009-02-24 Agensys, Inc. Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
ATE346305T1 (de) * 2001-09-24 2006-12-15 Gruenenthal Gmbh Screeningverfahren für verschiedene indikationen mit bnpi und/oder dnpi
US7265214B2 (en) * 2001-10-19 2007-09-04 Rigel Pharmaceuticals, Inc. Germinal center kinase proteins, compositions and methods of use
EP1512007A4 (fr) * 2001-10-29 2005-08-17 Millennium Pharm Inc 32235, membre de la famille de l'aminotransferase humaine et ses utilisations
EP1439864A4 (fr) * 2001-10-31 2004-12-22 Millennium Pharm Inc Procedes de traitement et de diagnostic de troubles de nature tumorigene et/ou angiogene recourant au 32616
EP1440169A4 (fr) * 2001-10-31 2005-09-21 Millennium Pharm Inc Procedes et compositions pour le traitement et le diagnostic d'algies utilisant le 57749
DE60220621T2 (de) 2001-11-09 2008-03-06 Proteologics, Inc. Posh Nukleinsäure, Polypeptide und darauf bezogene Verfahren
AU2002360460A1 (en) * 2001-12-03 2003-06-17 Nuvelo, Inc. Methods and materials relating to novel polypeptides and polynucleotides
EP1450852B1 (fr) * 2001-12-04 2007-01-17 DeveloGen Aktiengesellschaft Acides nucleiques et peptides de ptp10d intervenant dans la regulation de l'homeostasie energetique
US20060051852A1 (en) * 2001-12-12 2006-03-09 Smith Thomas M Apyrase polypeptides and nucleic acids encoding same
WO2003051917A2 (fr) * 2001-12-18 2003-06-26 Endocube Sas Nouvelles proteines associees a la mort, et mecanismes d'action de thap1 et para4 dans la maitrise de l'apoptose
US7858297B2 (en) * 2001-12-18 2010-12-28 Centre National De La Recherche Scientifique Cnrs Chemokine-binding protein and methods of use
EP1473365A1 (fr) * 2002-02-04 2004-11-03 Takeda Chemical Industries, Ltd. Inhibiteurs d'angiogenese
GB0205112D0 (en) * 2002-03-05 2002-04-17 Pantherix Ltd Enzyme
WO2003076072A1 (fr) 2002-03-11 2003-09-18 Japan Science And Technology Agency Catalyseur de zirconium chiral pratique
DE10212397A1 (de) * 2002-03-20 2003-10-16 Universitaetsklinikum Freiburg Repressor der Skelettmuskeldifferenzierung, dafür kodierende Nucleinsäure und dessen Verwendung in Diagnostik und Therapie
US20050065082A1 (en) * 2002-03-29 2005-03-24 Hirofumi Doi C-jun phosphorylation inhibitors
WO2003082342A1 (fr) * 2002-04-01 2003-10-09 National Institute Of Advanced Industrial Science And Technology Utilisation du gene k1aa0172 pour le traitement et le diagnostic de maladies et decouverte de medicaments
US7622443B2 (en) 2002-04-26 2009-11-24 California Institute Of Technology Method for inhibiting pro-angiogenic activities of endothelial cells selectively at a site of neoangiogenesis in a mammal by administration of the extracellular domain of D1-1 polypeptides
US7538088B2 (en) 2002-04-26 2009-05-26 California Institute Of Technology Method for inhibiting angiogenesis by administration of the extracellular domain of D1-1 polypeptide
DE10222845A1 (de) * 2002-05-23 2003-12-04 Dresden Arzneimittel Klonierung, Expression und Charakterisierung der Gesamtsequenz von Phosphodiesterase 8B
WO2004003165A2 (fr) * 2002-06-28 2004-01-08 Imclone Systems Incorporated Nouvelles sequences polynucleotidiques et polypeptidiques et leurs utilisations
CA2493007A1 (fr) * 2002-07-19 2004-01-29 Cellzome Ag Complexes proteiques de la proteine activatrice de la transcription de tip60
US7135556B2 (en) 2002-07-19 2006-11-14 Schering Corporation NPC1L1 (NPC3) and methods of use thereof
JP2004290170A (ja) * 2002-08-02 2004-10-21 Takeda Chem Ind Ltd 疾患関連遺伝子の用途
TW200413725A (en) * 2002-09-30 2004-08-01 Oncotherapy Science Inc Method for diagnosing non-small cell lung cancers
US7056685B1 (en) 2002-11-05 2006-06-06 Amgen Inc. Receptor ligands and methods of modulating receptors
WO2004046342A2 (fr) * 2002-11-20 2004-06-03 Biogen Idec Inc. Nouvelles cibles geniques et ligands se liant a ces cibles dans le traitement et le diagnostic de carcinomes
WO2004055050A2 (fr) * 2002-12-10 2004-07-01 Endocube Sas Proteines thap tenant lieu de recepteurs nucleaires des chimiokines et leurs roles dans la regulation transcriptionnelle, la proliferation cellulaire et la differenciation cellulaire
JP4140951B2 (ja) * 2002-12-18 2008-08-27 独立行政法人科学技術振興機構 転写制御因子ｚｈｘ３
WO2004061108A1 (fr) * 2002-12-29 2004-07-22 Toudai Tlo, Ltd. Recepteur de l'adiponectine et gene codant pour ce recepteur
EP1585815A4 (fr) * 2003-01-21 2006-02-22 Bristol Myers Squibb Co Polynucleotide codant une nouvelle co-enzyme d'acyle a, monoacylglycerol acyltransferase-2 (mgat2), et utilisations de ceux-ci
CN1747744B (zh) * 2003-02-03 2011-07-27 独立行政法人科学技术振兴机构 使用otx2基因再生和新生视网膜感光细胞
WO2005051988A2 (fr) * 2003-03-03 2005-06-09 Genentech, Inc. Compositions et procedes permettant de traiter un lupus erythemateux systemique
WO2004098515A2 (fr) * 2003-04-30 2004-11-18 Agensys, Inc. Acides nucleiques et proteines correspondantes appelees 109p1d4 utiles dans le traitement et la detection du cancer
WO2004104218A1 (fr) * 2003-05-23 2004-12-02 Bayer Healthcare Ag Agents diagnostiques et therapeutiques destines a des maladies associees a x-prolyl aminopeptidase 1 (xpnpep1)
WO2005023855A2 (fr) * 2003-09-10 2005-03-17 Friedrich-Alexander-Uni- Versitatet Erlangen- Nuernberg Gene et proteine k203
WO2005030953A1 (fr) * 2003-09-30 2005-04-07 Daiichi Pharmaceutical Co., Ltd. Gene de tetrahydrofolate synthase
WO2005059504A2 (fr) * 2003-12-12 2005-06-30 Bayer Healthcare Ag Diagnostics et therapeutique destines au traitement de maladies associees au recepteur couple aux proteines g gpr34 (gpr34)
US7901893B2 (en) 2004-01-16 2011-03-08 Merck Sharp & Dohme Corp. NPC1L1 (NPC3) and methods of identifying ligands thereof
WO2005077091A2 (fr) * 2004-02-10 2005-08-25 Trustees Of Dartmouth College Compositions de nicotinamide riboside kinase et procedes d'utilisation
US8010189B2 (en) 2004-02-20 2011-08-30 Brainsgate Ltd. SPG stimulation for treating complications of subarachnoid hemorrhage
US8055347B2 (en) 2005-08-19 2011-11-08 Brainsgate Ltd. Stimulation for treating brain events and other conditions
US9233245B2 (en) 2004-02-20 2016-01-12 Brainsgate Ltd. SPG stimulation
EP1786833A4 (fr) * 2004-03-19 2009-02-25 Univ Yale Detection, isolement et utilisations de la renalase (monoamine oxydase de type c)
ATE430763T1 (de) * 2004-03-30 2009-05-15 Nsgene As Therapeutische verwendung des wachstumsfaktors nsg33
US20050222040A1 (en) * 2004-04-05 2005-10-06 Blm Group, Inc. Vertebrate peptide modulators of lipid metabolism
DK1742966T3 (da) 2004-04-22 2014-02-03 Agensys Inc Antistoffer og molekyler afledt deraf som binder til STEAP-1 proteiner
US7709611B2 (en) 2004-08-04 2010-05-04 Amgen Inc. Antibodies to Dkk-1
WO2006069592A2 (fr) * 2004-12-31 2006-07-06 Vereniging Voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek En Patientenzorg Methode permettant de diagnostiquer et/ou de predire la toxemie preeclamptique et/ou des troubles associes
FI20050011A (fi) * 2005-01-05 2006-07-06 Jurilab Ltd Oy Menetelmä ja testipakkaus tyypin 2 diabetes mellituksen riskin havaitsemiseksi
WO2006074914A2 (fr) * 2005-01-13 2006-07-20 Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute For Biomedical Research Helicase d'arn humaine et ses utilisations therapeutiques
US7521195B1 (en) 2005-07-21 2009-04-21 Celera Corporation Lung disease targets and uses thereof
WO2007059357A1 (fr) 2005-11-21 2007-05-24 Yale University Procedes de regulation de la renalase (monoamine oxydase c)
WO2007060899A1 (fr) * 2005-11-22 2007-05-31 National University Corporation Nagoya University Application d'une protéine se liant à l’actine à une maladie associée à la motilité cellulaire
US7910698B2 (en) 2006-02-24 2011-03-22 Schering Corporation NPC1L1 orthologues
AU2007308792B2 (en) 2006-10-27 2013-01-24 Genentech, Inc. Antibodies and immunoconjugates and uses therefor
EP2152292A4 (fr) * 2007-05-02 2011-04-27 Snu R&Db Foundation Inhibiteur de l'angiogenèse comprenant de la météorine en tant que principe actif
PL3009148T3 (pl) 2007-07-02 2019-03-29 Oncomed Pharmaceuticals, Inc. Kompozycje oraz sposoby leczenia i diagnozowania nowotworu
EP2170374A2 (fr) * 2007-07-03 2010-04-07 Andreas Reichert Procédé de traitement de maladies liées à un dysfonctionnement mitochondrial
EP2178551A4 (fr) * 2007-07-24 2010-07-21 Sanare Invest As Nouveaux peptides
CN101910196A (zh) 2007-12-28 2010-12-08 诺沃-诺迪斯克有限公司 Ddr1-介导的从它们的祖细胞向胰腺内分泌细胞的细胞纯化
CA2730710C (fr) 2008-07-24 2021-06-08 Nsgene A/S Utilisation therapeutique d'un facteur de croissance, metrnl
ES2638779T3 (es) 2009-03-16 2017-10-24 Pangu Biopharma Limited Composiciones y procedimientos que comprenden variantes de splicing de histidil-tarn sintetasa que tienen actividades biológicas no canónicas
AR075989A1 (es) 2009-04-10 2011-05-11 Lilly Co Eli Anticuerpo dkk -1 (dickkopf-1) humano disenado por ingenieria
US8815779B2 (en) 2009-09-16 2014-08-26 SwitchGear Genomics, Inc. Transcription biomarkers of biological responses and methods
NZ599707A (en) 2009-11-30 2014-07-25 Genentech Inc Antibodies for treating and diagnosing tumors expressing slc34a2 (tat211 = seqid2 )
WO2011072265A1 (fr) 2009-12-11 2011-06-16 Atyr Pharma, Inc. AMINOACYL-ARNt SYNTHÉTASES DESTINÉES À MODULER UNE INFLAMMATION
CA2798301C (fr) 2010-05-04 2020-09-15 Atyr Pharma, Inc. Decouverte innovante de compositions therapeutiques, diagnostiques et a base d'anticorps liees a des fragments proteiques de glutamyl-prolyl-arnt-synthetases
KR20180059953A (ko) 2010-07-12 2018-06-05 에이티와이알 파마, 인코포레이티드 히스티딜­trna 합성효소의 단백질 단편에 관련된 치료적, 진단적, 및 항체 조성물의 혁신적 발견
KR101886029B1 (ko) 2010-10-01 2018-08-07 호바 세라퓨틱스 에이피에스 무해자극통증, 통각과민증, 자발통증 및 헛통증의 치료를 위한 메테오린의 용도
AU2012284254B2 (en) 2011-07-15 2015-07-09 Oncomed Pharmaceuticals, Inc. RSPO binding agents and uses thereof
KR102075881B1 (ko) 2011-09-05 2020-02-11 호바 세라퓨틱스 에이피에스 이질통, 통각과민증, 자발통 및 환상통의 치료
MX356107B (es) 2012-02-16 2018-05-15 Atyr Pharma Inc Histidil-arnt sintetasas para tratar enfermedades autoinmunes e inflamatorias.
BR112015000776A2 (pt) 2012-07-13 2017-08-15 Oncomed Pharm Inc Agentes de ligação à rspo3 e usos dos mesmos
EP2742935A1 (fr) * 2012-12-14 2014-06-18 Tissue Med Biosciences Forschungs- und Entwicklungsgesellschaft mbH SERF2 pour traiter l'atrophie ou augmenter la croissance cellulaire
US9587235B2 (en) 2013-03-15 2017-03-07 Atyr Pharma, Inc. Histidyl-tRNA synthetase-Fc conjugates
EP2878335B1 (fr) 2013-11-10 2018-01-03 Brainsgate Ltd. Implant et système d'implantation pour stimulateur neural
EP3193935A4 (fr) 2014-09-16 2018-03-21 Oncomed Pharmaceuticals, Inc. Traitement de maladies fibrotiques
EP3093043B1 (fr) 2015-05-13 2018-11-14 Brainsgate Ltd. Implant et système de distribution pour stimulateur neural
CN110049769A (zh) 2016-12-04 2019-07-23 阿拉维·霍拉萨尼·默哈达姆·马塞尔·维克托 治疗与线粒体应激相关的疾病的方法
US10905766B2 (en) * 2017-03-23 2021-02-02 Oregon State University Therapeutic compositions and methods for treatment of muscle wasting diseases
ES2955852T3 (es) 2017-04-03 2023-12-07 Hoffmann La Roche Anticuerpos de unión a STEAP-1
AU2018256435A1 (en) 2017-04-20 2019-11-07 Atyr Pharma, Inc. Compositions and methods for treating lung inflammation
CN110910960B (zh) * 2019-11-30 2022-07-08 浙江天科高新技术发展有限公司 一种鲍曼不动杆菌分子血清型快速分析方法
PE20240888A1 (es) * 2020-12-08 2024-04-24 Imagine Pharma Llc Composiciones y metodos para tratar heridas

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998049306A1 (fr) * 1997-04-29 1998-11-05 Incyte Pharmaceuticals, Inc. Lectine humaine de type c
WO1998054209A2 (fr) * 1997-05-31 1998-12-03 Peptide Therapeutics Limited Mafa humaine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5474796A (en) * 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998049306A1 (fr) * 1997-04-29 1998-11-05 Incyte Pharmaceuticals, Inc. Lectine humaine de type c
WO1998054209A2 (fr) * 1997-05-31 1998-12-03 Peptide Therapeutics Limited Mafa humaine

Non-Patent Citations (13)

* Cited by examiner, † Cited by third party
Title
DATABASE EBI 1 November 1996 (1996-11-01), XP002329122, retrieved from EBI Database accession no. Q04490 *
DATABASE EMBL [online] 15 November 1992 (1992-11-15), "Homo Sapiens P5-1 mRNA, complete cds.", XP002329509, retrieved from EBI Database accession no. HSMHP *
DATABASE EMBL [online] 19 January 1998 (1998-01-19), "nx26e06.s1 NCI_CGAP_GC4 Homo sapiens cDNA clone IMAGE:1257250 3', mRNA sequence.", XP002346073, retrieved from EBI Database accession no. AA742567 *
DATABASE EMBL [online] 25 January 1999 (1999-01-25), "CITBI-E1-2541D22.TR CITBI-E1 Homo sapiens genomic clone 2541D22, genomic survey sequence.", XP002346074, retrieved from EBI Database accession no. AQ356422 *
DATABASE EMBL [online] 27 August 1998 (1998-08-27), "Homo sapiens PAC clone RP4-701O16 from 7, complete sequence.", XP002346072, retrieved from EBI Database accession no. AC005531 *
DATABASE EMBL [online] 4 December 1998 (1998-12-04), "Homo sapiens DNA, P5-1-hom region.", XP002329406, retrieved from EBI Database accession no. D88650 *
DATABASE EMBL 21 April 1994 (1994-04-21), "H.sapiens P5-1g DNA", XP002329407, retrieved from EBI Database accession no. Z31714 *
DATABASE EMBL 30 June 1999 (1999-06-30), "wi73f11.x1 NCI_CGAP_Kid12 Homo sapiens cDNA clone IMAGE:2398989 3' similar to TR:Q04490 Q04490 P5-1 PROTEIN.", XP002329408, retrieved from EBI Database accession no. AI765329 *
DATABASE UniProt 1 June 1998 (1998-06-01), "Mast cell function-associated antigen", XP002346076, retrieved from EBI Database accession no. O43198 *
DATABASE UniProt 1 November 1998 (1998-11-01), "ITIM-containing receptor MAFA_l (Mast cell function-associated antigen homolog)", XP002346075, retrieved from EBI Database accession no. 075613 *
See also references of WO0157190A3 *
SHIINA TAKASHI ET AL.: "Physical mapping between the S and HLA-E genes in the human MHC class I region: Construction of a BAC, PAC, and cosmid contig", IMMUNOGENETICS, vol. 48, no. 6, November 1998 (1998-11-01), pages 402 - 407, XP002329404, ISSN: 0093-7711 *
VERNET C. ET AL.: "A novel coding sequence belonging to a new multicopy gene family mapping within the human MHC class I region", IMMUNOGENETICS, vol. 38, no. 1, 1993, pages 47 - 53, XP002904811, ISSN: 0093-7711 *

Also Published As

Publication number Publication date
CA2399776A1 (fr) 2001-08-09
AU2001234944A8 (en) 2006-12-21
EP1572987A2 (fr) 2005-09-14
AU2001234944A1 (en) 2001-08-14
WO2001057190A3 (fr) 2006-11-16
WO2001057190A2 (fr) 2001-08-09

Similar Documents

Publication Publication Date Title
AU2001234944A8 (en) Novel nucleic acids and polypeptides
EP1325120A4 (fr) Acides nucleiques et polypeptides
EP1341804A4 (fr) Nouveaux acides nucleiques et polypeptides
EP1504099A4 (fr) Nouveaux acides nucleiques et polypeptides
EP1381621A4 (fr) Nouveaux acides nucleiques et polypeptides
EP1432800A4 (fr) Nouveaux acides nucleiques et polypeptides
EP1470238A4 (fr) Nouveaux acides nucleiques et polypeptides
EP1242443A4 (fr) Nouveaux acides nucleiques et polypeptides
AU2001249251A1 (en) Novel nucleic acids and polypeptides
AU2001243142A1 (en) Novel nucleic acids and polypeptides
AU2001290548A1 (en) Novel nucleic acids and polypeptides
AU2001245280A1 (en) Novel nucleic acids and polypeptides
AU2001233041A1 (en) Novel nucleic acids and polypeptides
AU2001238347A1 (en) Novel nucleic acids and polypeptides
IL206414A0 (en) Novel receptor nucleic acids and polypeptides
AU2001263006A1 (en) Novel nucleic acids and polypeptides
AU2001233017A1 (en) Novel nucleic acids and polypeptides
EP1430112A4 (fr) Nouveaux acides nucleiques et polypeptides
EP1276751A4 (fr) Nouveaux acides nucleiques et polypeptides
EP1368475A4 (fr) Nouveaux acides nucleiques et nouveaux polypeptides
AU2001292561A1 (en) Nucleic acids and polypeptides
AU2001250872A1 (en) Novel nucleic acids and polypeptides
AU2001277840A1 (en) Novel nucleic acids and polypeptides
EP1341803A4 (fr) Nouveaux acides nucleiques et polypeptides
AU2001263005A8 (en) Novel nucleic acids and polypeptides

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20020826

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

A4 Supplementary search report drawn up and despatched

Effective date: 20051012

PUAK Availability of information related to the publication of the international search report

Free format text: ORIGINAL CODE: 0009015

RIC1 Information provided on ipc code assigned before grant

Ipc: C07H 21/04 20060101AFI20070319BHEP

17Q First examination report despatched

Effective date: 20080328

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION HAS BEEN WITHDRAWN

18W Application withdrawn

Effective date: 20080515