EP1572218A4 - Lokalanästhetikum mit ester-kombination - Google Patents

Lokalanästhetikum mit ester-kombination

Info

Publication number
EP1572218A4
EP1572218A4 EP03800157A EP03800157A EP1572218A4 EP 1572218 A4 EP1572218 A4 EP 1572218A4 EP 03800157 A EP03800157 A EP 03800157A EP 03800157 A EP03800157 A EP 03800157A EP 1572218 A4 EP1572218 A4 EP 1572218A4
Authority
EP
European Patent Office
Prior art keywords
local anesthetic
ester combination
combination local
ester
anesthetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03800157A
Other languages
English (en)
French (fr)
Other versions
EP1572218A2 (de
Inventor
Steven L Shafer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leland Stanford Junior University
Original Assignee
Leland Stanford Junior University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leland Stanford Junior University filed Critical Leland Stanford Junior University
Publication of EP1572218A2 publication Critical patent/EP1572218A2/de
Publication of EP1572218A4 publication Critical patent/EP1572218A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245Amino benzoic acid types, e.g. procaine, novocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof
    • A61K31/625Salicylic acid; Derivatives thereof having heterocyclic substituents, e.g. 4-salicycloylmorpholine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • A61P23/02Local anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
EP03800157A 2002-12-20 2003-12-18 Lokalanästhetikum mit ester-kombination Withdrawn EP1572218A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32731002A 2002-12-20 2002-12-20
US327310 2002-12-20
PCT/US2003/041219 WO2004058329A2 (en) 2002-12-20 2003-12-18 Ester combination local anesthetic

Publications (2)

Publication Number Publication Date
EP1572218A2 EP1572218A2 (de) 2005-09-14
EP1572218A4 true EP1572218A4 (de) 2007-05-16

Family

ID=32680753

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03800157A Withdrawn EP1572218A4 (de) 2002-12-20 2003-12-18 Lokalanästhetikum mit ester-kombination

Country Status (10)

Country Link
EP (1) EP1572218A4 (de)
JP (1) JP2006513224A (de)
KR (1) KR20050085736A (de)
CN (1) CN1729004A (de)
AU (1) AU2003299885A1 (de)
BR (1) BR0317519A (de)
CA (1) CA2507511A1 (de)
MX (1) MXPA05006771A (de)
NO (1) NO20053203L (de)
WO (1) WO2004058329A2 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060062836A1 (en) * 2004-09-21 2006-03-23 Carter Stephen G Methods of device-assisted drug delivery
DK1863468T3 (en) 2005-03-15 2016-08-15 Animal Ethics Pty Ltd A topical anesthetic composition
ITMI20051633A1 (it) * 2005-09-06 2007-03-07 Sint Sa Nuovo uso di una composizione comprendente cloroprocaina hcl nuova composizione comprendente cloroprocaina hcl e metodo per la sua fabbricazione
JP2010500969A (ja) * 2006-07-19 2010-01-14 ファーマコフォア,インク. 麻酔薬
WO2008051527A2 (en) * 2006-10-23 2008-05-02 Psivida, Inc. Sustained release of agents for localized pain management
WO2009091546A1 (en) * 2008-01-18 2009-07-23 Pharmacofore, Inc. Anesthetic compounds
ITMI20122120A1 (it) 2012-12-12 2014-06-13 Sint Sa Composizione farmaceutica a base di cloroprocaina per la somministrazione intratecale ripetuta
ITCR20130004A1 (it) * 2013-02-05 2014-08-06 Vincenzo Vigna Farmaco salvavita
US10117847B2 (en) * 2015-12-04 2018-11-06 Ventis Pharma Extended duration local anesthetic formulation
DE102016215037A1 (de) 2016-08-11 2018-02-15 Franz Baur Federvorrichtung und Verbindungsvorrichtung
JP2020533321A (ja) * 2017-09-15 2020-11-19 シンテティカ ソシエテ アノニム クロロプロカインの表面麻酔製剤
WO2019226599A1 (en) * 2018-05-22 2019-11-28 Alkalidx, Inc. Diagnostics and treatments of anesthetic insensitive subjects
JP6886551B1 (ja) * 2020-11-06 2021-06-16 医療法人祥和会 歯科用の局所麻酔液

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5446070A (en) * 1991-02-27 1995-08-29 Nover Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
WO2001030287A1 (en) * 1999-10-25 2001-05-03 Epicept Corporation Local prevention or amelioration of pain from surgically closed wounds
WO2001041550A2 (en) * 1999-10-22 2001-06-14 Transdermatech, Inc. Topical anesthetic formulation
WO2001054679A2 (en) * 2000-01-27 2001-08-02 Children's Hospital Research Foundation Transdermal composition containing an anesthetic and a vasodilator agent

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6326020B1 (en) * 1997-05-16 2001-12-04 Children's Medical Center Corporation Local anesthetic formulations

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5446070A (en) * 1991-02-27 1995-08-29 Nover Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
WO2001041550A2 (en) * 1999-10-22 2001-06-14 Transdermatech, Inc. Topical anesthetic formulation
WO2001030287A1 (en) * 1999-10-25 2001-05-03 Epicept Corporation Local prevention or amelioration of pain from surgically closed wounds
WO2001054679A2 (en) * 2000-01-27 2001-08-02 Children's Hospital Research Foundation Transdermal composition containing an anesthetic and a vasodilator agent

Also Published As

Publication number Publication date
AU2003299885A1 (en) 2004-07-22
JP2006513224A (ja) 2006-04-20
NO20053203L (no) 2005-09-19
KR20050085736A (ko) 2005-08-29
CN1729004A (zh) 2006-02-01
WO2004058329A2 (en) 2004-07-15
WO2004058329A3 (en) 2004-12-29
BR0317519A (pt) 2005-11-16
EP1572218A2 (de) 2005-09-14
CA2507511A1 (en) 2004-07-15
NO20053203D0 (no) 2005-06-30
MXPA05006771A (es) 2005-09-08

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20050622

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Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

AX Request for extension of the european patent

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DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20070416

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Effective date: 20060201