EP1521639B1 - Buse de pulverisation a fente annulaire rotative - Google Patents

Buse de pulverisation a fente annulaire rotative Download PDF

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Publication number
EP1521639B1
EP1521639B1 EP03763874A EP03763874A EP1521639B1 EP 1521639 B1 EP1521639 B1 EP 1521639B1 EP 03763874 A EP03763874 A EP 03763874A EP 03763874 A EP03763874 A EP 03763874A EP 1521639 B1 EP1521639 B1 EP 1521639B1
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EP
European Patent Office
Prior art keywords
nozzle
atomizing nozzle
flow channel
anyone
wall
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP03763874A
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German (de)
English (en)
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EP1521639A1 (fr
Inventor
Herbert Hüttlin
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Individual
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Individual
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Priority to SI200330120T priority Critical patent/SI1521639T1/sl
Publication of EP1521639A1 publication Critical patent/EP1521639A1/fr
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Publication of EP1521639B1 publication Critical patent/EP1521639B1/fr
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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B1/00Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means
    • B05B1/30Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to control volume of flow, e.g. with adjustable passages
    • B05B1/32Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to control volume of flow, e.g. with adjustable passages in which a valve member forms part of the outlet opening
    • B05B1/323Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to control volume of flow, e.g. with adjustable passages in which a valve member forms part of the outlet opening the valve member being actuated by the pressure of the fluid to be sprayed
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B3/00Spraying or sprinkling apparatus with moving outlet elements or moving deflecting elements
    • B05B3/02Spraying or sprinkling apparatus with moving outlet elements or moving deflecting elements with rotating elements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B3/00Spraying or sprinkling apparatus with moving outlet elements or moving deflecting elements
    • B05B3/02Spraying or sprinkling apparatus with moving outlet elements or moving deflecting elements with rotating elements
    • B05B3/10Spraying or sprinkling apparatus with moving outlet elements or moving deflecting elements with rotating elements discharging over substantially the whole periphery of the rotating member, i.e. the spraying being effected by centrifugal forces
    • B05B3/105Fan or ventilator arrangements therefor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/02Spray pistols; Apparatus for discharge
    • B05B7/06Spray pistols; Apparatus for discharge with at least one outlet orifice surrounding another approximately in the same plane
    • B05B7/062Spray pistols; Apparatus for discharge with at least one outlet orifice surrounding another approximately in the same plane with only one liquid outlet and at least one gas outlet
    • B05B7/066Spray pistols; Apparatus for discharge with at least one outlet orifice surrounding another approximately in the same plane with only one liquid outlet and at least one gas outlet with an inner liquid outlet surrounded by at least one annular gas outlet
    • B05B7/067Spray pistols; Apparatus for discharge with at least one outlet orifice surrounding another approximately in the same plane with only one liquid outlet and at least one gas outlet with an inner liquid outlet surrounded by at least one annular gas outlet the liquid outlet being annular
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B1/00Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means
    • B05B1/26Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means with means for mechanically breaking-up or deflecting the jet after discharge, e.g. with fixed deflectors; Breaking-up the discharged liquid or other fluent material by impinging jets
    • B05B1/262Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means with means for mechanically breaking-up or deflecting the jet after discharge, e.g. with fixed deflectors; Breaking-up the discharged liquid or other fluent material by impinging jets with fixed deflectors
    • B05B1/265Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means with means for mechanically breaking-up or deflecting the jet after discharge, e.g. with fixed deflectors; Breaking-up the discharged liquid or other fluent material by impinging jets with fixed deflectors the liquid or other fluent material being symmetrically deflected about the axis of the nozzle

Definitions

  • the invention relates to a sputtering nozzle, with a first, in cross-section annular flow channel for guiding one to atomizing medium, by two radially from each other spaced walls is bounded and in an annular Nozzle opening opens, and with a second, the first orbiting Flow channel for guiding a gaseous spray medium, which also opens into an annular nozzle opening.
  • Such a sputtering nozzle is known for example from DE 702 485 and DE 197 49 071 A1 known.
  • DE 702 485 shows a Zerstänbungdüse according to the preamble of claim 1.
  • Such atomizing nozzles are used a medium to be atomized, usually a liquid, sometimes also a powder, with the aid of a gaseous spray medium to spray.
  • the medium to be atomized is under pressure through the annular or slit-shaped flow channel to an annular gap-shaped Transported nozzle opening.
  • This first annular flow channel is of a second also encircled annular flow channel and this opens adjacent to the first flow channel also in one annular or slit-shaped nozzle opening.
  • spray such nozzles axially or more or less from the axial axis laterally out with ever-increasing spray angle, with spray angles of up to 180 ° and a wrap angle 360 ° around the mouth of the head.
  • Such nozzles are widely used in devices for treating of particulate material, for example for granulation or coating these particles.
  • a sticky liquid that serves to spray the particles to larger agglomerates, so the desired granules, too stick together.
  • a coating layer is applied to the surface sprayed.
  • Such devices are found mainly in the pharmaceutical industry Use, there are tablet ingredients that as Powdered powders are produced, too manageable, for example granulated to tablet compressible powders.
  • the nozzles spray vertically upwards, so are designed as standing nozzles, spray inclined, horizontal or in some cases vertical directed from top to bottom.
  • atomizing nozzles By such atomizing nozzles are suspensions, dispersions or to spray solutions and these are also in so-called. Apply "hot-melt” processes involving wax melting or Hard fat can be processed under thermal influence.
  • the worked annular flow channels with liquid cross sections which are in the range of ⁇ 0.25 mm.
  • the one to be treated Well swirled around the nozzle or moved, so that then, at a circumference due to blockages unequal Spray nozzle achieved an irregular treatment result becomes.
  • the two Walls also relative to each other axially displaceable, whereby the gap width of the nozzle opening of the first annular flow channel is changeable.
  • Usual annular gaps in such atomizing nozzles have a Width of 0.1 to about 0.25 mm, and it is desirable to 1 up to 5 grams of medium to be sprayed per millimeter of length To drive out gap.
  • the axial mobility now makes it possible, depending on the nature of the to be sprayed medium, that sets the gap height itself.
  • Will a particular medium with a certain pressure performed by the first flow channel exert intrinsic Properties, for example, in the case of a liquid whose viscosity, for emulsions, their flowability and toughness, a significant influence on the amount per mm of length can pass through a gap.
  • there are liquids that are relatively simple drive through such a gap others need but for the same exit amount a slightly wider gap.
  • conveying elements can also be used as mechanical Means are used to any entrained solid lumps purposeful transport and shred to distress.
  • one wall is stationary and the other wall is rotatable.
  • This measure has the constructive advantage that only one of the two walls has to be moved, and accordingly only for one of these walls corresponding drive elements must be present.
  • That wall which is rotatable is, at the same time axially movable.
  • control takes place the axial mobility through the subsidized Medium itself.
  • the axial Displacement designed such that at rest, the Nozzle opening of the first flow channel is closed.
  • gravity can be the restoring force be used, so that when a stationary nozzle, the one movable Wall by relative displacement to another due to the Gravity is moved to the closed position.
  • the axial Displacement of the walls designed such that at rest also closed the nozzle opening of the second flow channel is.
  • This measure has the advantage that both nozzle openings at rest are closed.
  • the rotatable carries Wall at the outside of a atomizing nozzle head one Fan, through which the head in the area of the nozzle openings is free from any attachments.
  • Vacuum areas are formed that have been vagabonding, just Re-apply sprayed liquid droplets and put on deposit the mouthhead. That's why it comes to one there Agglomeration or gradually to a structure of dried-on Solid from the sprayed liquid.
  • the one Wall formed as the outside of a central spindle the is rotatable.
  • This measure has the constructive advantage that by a structurally simple means, namely the central spindle, the rotating wall is created.
  • the conveying elements designed as impeller sections.
  • This measure has the advantage that thereby a particularly uniform promotion of the movement of the medium to be sprayed is possible.
  • impeller sections on the outside of the aforementioned formed central spindle, it is on the one hand constructive extremely easy to portray and it can be a special favorable and targeted promotion can be achieved.
  • the spindle driven by a pneumatically operated motor.
  • the spindle is on attached a drive pin, which has a certain axial mobility the spindle allowed.
  • the degree of mobility for example, by a kausguerzapfen, in a slot in the drive pin runs, be limited.
  • FIG. 1 An atomizing nozzle shown in Figs. 1 and 2 is shown in Figs their entirety designated by the reference numeral 10.
  • the atomizing nozzle 10 has an approximately rod-shaped nozzle body 12, on one, in the illustration of Fig. 1 and 2 lower end of a motor 14 is flanged.
  • a first annular or annular gap-shaped Flow channel 16 is formed.
  • This first flow channel 16 is on the inside by an inner Wall 18 bounded, which is the outside 20 of a central Spindle 22 is.
  • the spindle 22 is on an upstanding angular drive pin 24 of the engine 24 attached and points to its lower End a corresponding slot 26.
  • the connector is such that also has a certain axial Mobility of the spindle 22 is given, with their meaning and purpose later described in connection with the operation becomes.
  • the axial mobility or limiting the dimension of the axial Movement can be created by that in the drive pin a raised slot is recessed in the a transverse bolt is received, which is in a radial bore of the Spindle 22 in the region of the slot 26 inserted.
  • the first flow channel 16 is on the outside by an outer Wall 30 bounded by an inside of a central continuous central bore or opening 34 in the nozzle body 12 is formed. Both the spindle 22 and the nozzle body 12 are opposite to the engine 14 trumpet-like in a widening 36 or in a widening 38, as can be seen in particular from Fig. 1a.
  • an approximately horizontally oriented nozzle opening 40 is in Shape of a 360 ° circumferential annular gap 42 is formed.
  • the width of the annular gap 42 is due to the axial mobility the spindle 22 changeable, the change in Range is between 0.1 mm and 0.25 mm.
  • the first flow channel 16 is, as shown particularly in FIG. 2 can be seen connected to a lateral port 44, so that via this port 44 in the first flow channel 16 a medium to be atomized, for example a liquid 45, fed through the first flow channel 16 transported therethrough and can exit via the annular gap 42.
  • a medium to be atomized for example a liquid 45
  • the transport and the promotion of this liquid 45 is even more by conveying elements 48 in the form of two impeller sections 46 and 46 'on the outside 22 of the spindle 22, wherein the height of an impeller is such that this approximately the Slit width of the first flow channel 16 in the interior of the atomizing nozzle 10 corresponds.
  • the profile of the impeller 46 so that this approximately flat on the inside 32 of the central opening 34 is applied, of course, too other profiles possible, for example, rounded or pointed Wheel profiles.
  • a second flow channel 50 is provided.
  • This second flow channel 50 surrounds the first inner Flow channel 16 and opens in a same direction expansion 52 in a nozzle opening 54, which also takes the form of a Annular gap 56 has.
  • the annular gap 56 is arranged that it is immediately adjacent to the annular gap 42, in the illustrated Embodiment of the standing atomizing nozzle 10 directly below the first annular gap 42.
  • the second flow channel 50 is bounded on the inside by the nozzle body 12, on its outside by a rotatable sleeve 58.
  • the Sleeve 58 is screwed into the nozzle body 12 via a thread 60.
  • the sleeve 58 is on its outside, as it is made in particular Fig. 2 can be seen, provided with a scale 62.
  • the second flow channel 52 is via a radially projecting Port 64 connected to the outside world, via which a gaseous Medium in the form of spray air 65 introduced into the nozzle body 12 becomes.
  • the motor 14 is designed as a pneumatically operated motor, i.e. Compressed air 67 is introduced through an inlet 66 and this compressed air 67 is performed by an outlet 68 again.
  • the engine 14 is powered by the aforementioned compressed air controlled and driven, so that the spindle 22 rotates.
  • the speed depends on the particular application to be sprayed medium and can be in the range of 1 to 1000 revolutions per minute.
  • a too spraying medium for example, a sticky to be sprayed Liquid for granulation, conveyed and over the annular gap 42 expressed.
  • the liquid can also come from an external source consist of molten substance.
  • This squeezed out liquid is replaced by that from the second Flow channel 50 or emerging from the nozzle opening 54 Spray air 65 sprayed to a fine mist, with the spray air usually under a pressure of 0.5 to 5.0 bar.
  • the gap width of the annular gap 56, out the spray air exits, changed by the rotatable sleeve 58 become.
  • the gap width of the annular gap 42 from which to be sprayed Liquid 45 exits regulated due to the axial mobility the spindle 22 by itself, on the one hand by the predetermined Fluid pressure of the liquid to be sprayed and in addition to a certain extent by the intrinsic Properties of the liquid, ie their viscosity or their Texture as emulsion, slurry or powder mixture.
  • a portion 88 of the outer edge of the Head 80 certain problem areas exist in which to and after after sprayed particles or in a fluidized bed apparatus apply floats around the particles. This area is indicated in Fig. 2 by the reference numeral 88.
  • FIGS. 3 and 4 show a variant embodiment. as regards the design of the atomizing nozzle as such, is the same as that in connection with Figs. 1 and 2 described embodiment.
  • a fan 82 mounted on the outside of the head 80 .
  • This fan 82 has a plurality of backward curved centrifugal fan blades 84, the air from an axial tube 86 suck in and, as in particular on the plan view of Fig. 4th can be seen by the arrow 89, blow out this air radially.
  • the designated in Fig. 2 by the reference numeral 88 critical area continuously blown, so that no unwanted attachments or accumulations of solids or Liquid particles arise.
  • This additionally blown air from the fan 82 may additionally be used to that shown in Fig. 2 Accompany spray cone 75 at its top, so this either to control, in addition to swirl or other Purposes.

Landscapes

  • Nozzles (AREA)
  • Vaporization, Distillation, Condensation, Sublimation, And Cold Traps (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Claims (16)

  1. Buse de pulvérisation avec un premier canal d'écoulement (16) de section transversale de forme annulaire pour le guidage d'un fluide (45) à pulvériser, qui est délimité par deux parois (18, 30) espacées radialement l'une de l'autre et qui débouche dans un orifice de buse (40) de forme annulaire, et avec un deuxième canal d'écoulement (50) entourant le premier (16) pour guider un fluide de pulvérisation (65) gazeux, qui débouche également dans un orifice de buse (54) de forme annulaire, caractérisée en ce que les parois (18, 30) délimitant le premier canal d'écoulement (16) peuvent tourner l'une par rapport à l'autre autour d'un axe longitudinal (70) de la buse.
  2. Buse de pulvérisation selon la revendication 1, caractérisée en ce que les deux parois (18, 30) peuvent aussi coulisser axialement l'une par rapport à l'autre, ce qui fait que la largeur de la fente de l'orifice de buse (40) est variable.
  3. Buse de pulvérisation selon la revendication 1 ou 2, caractérisée en ce que sur au moins l'une des parois (30) pouvant tourner l'une par rapport à l'autre sont disposés des éléments de transport (48) qui commandent un mouvement du fluide (45) à pulvériser transporté vers l'orifice de buse (40).
  4. Buse de pulvérisation selon l'une des revendications 1 à 3, caractérisée en ce qu'une paroi (30) est fixe et en ce que l'autre paroi (18) est réalisée tournante.
  5. Buse de pulvérisation selon l'une des revendications 2 à 4, caractérisée en ce qu'une paroi est fixe et en ce que l'autre paroi (18) peut coulisser axialement.
  6. Buse de pulvérisation selon l'une des revendications 2 à 5, caractérisée en ce que la paroi (30) qui est tournante est également en même temps mobile axialement.
  7. Buse de pulvérisation selon l'une des revendications 2 à 4, caractérisée en ce que la commande de la mobilité axiale s'effectue par le fluide (45) à pulvériser transporté.
  8. Buse de pulvérisation selon l'une des revendications 2 à 7, caractérisée en ce que la possibilité de coulissement axial est conçue de manière qu'à l'état de repos l'orifice de buse (40) du premier canal d'écoulement (16) est fermé.
  9. Buse de pulvérisation selon l'une des revendications 2 à 8, caractérisée en ce que la possibilité de coulissement axial s'effectue à l'encontre d'une force de rappel qui déplace la (les) paroi(s) coulissante(s) dans la position de fermeture de l'orifice de buse.
  10. Buse de pulvérisation selon l'une des revendications 2 à 9, caractérisée en ce que la possibilité de coulissement axial est conçue de manière qu'à l'état de repos l'orifice de buse (54) du deuxième canal d'écoulement (50) soit également fermé.
  11. Buse de pulvérisation selon l'une des revendications 1 à 10, caractérisée en ce que la paroi tournante porte, sur le côté extérieur d'une tête (80) de la buse de pulvérisation (10), un ventilateur (82) par lequel la tête (80) peut être dégagée d'éventuelles adhérences dans la zone des orifices de buse (40, 54).
  12. Buse de pulvérisation selon l'une des revendications 1 à 11, caractérisée en ce qu'une paroi (18) est réalisée en tant que côté extérieur (20) d'une broche (22) centrale qui peut tourner.
  13. Buse de pulvérisation selon l'une des revendications 3 à 12, caractérisée en ce que les éléments de transport (48) sont conçus comme des parties (46, 46') de roue de roulement.
  14. Buse de pulvérisation selon la revendication 12 ou 13, caractérisée en ce que la broche (22) est entraínée par un moteur (40) pouvant être commandé de manière pneumatique.
  15. Buse de pulvérisation selon la revendication 14, caractérisée en ce que la broche (22) est emmanchée sur un axe d'entraínement (24) du moteur (14) qui permet une certaine mobilité axiale de la broche (22).
  16. Buse de pulvérisation selon l'une des revendications 11 à 15, caractérisée en ce que le ventilateur (82) est calé sur une tête (80) de la broche (22).
EP03763874A 2002-07-16 2003-07-16 Buse de pulverisation a fente annulaire rotative Expired - Lifetime EP1521639B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SI200330120T SI1521639T1 (sl) 2002-07-16 2003-07-16 Razprsevalna soba z vrtljivo obrocasto rego

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10232863A DE10232863A1 (de) 2002-07-16 2002-07-16 Zerstäubungsdüse mit rotativem Ringspalt
DE10232863 2002-07-16
PCT/EP2003/007715 WO2004007085A1 (fr) 2002-07-16 2003-07-16 Buse de pulverisation a fente annulaire rotative

Publications (2)

Publication Number Publication Date
EP1521639A1 EP1521639A1 (fr) 2005-04-13
EP1521639B1 true EP1521639B1 (fr) 2005-11-30

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Family Applications (1)

Application Number Title Priority Date Filing Date
EP03763874A Expired - Lifetime EP1521639B1 (fr) 2002-07-16 2003-07-16 Buse de pulverisation a fente annulaire rotative

Country Status (10)

Country Link
EP (1) EP1521639B1 (fr)
JP (1) JP2006501048A (fr)
CN (1) CN100441310C (fr)
AT (1) ATE311257T1 (fr)
AU (1) AU2003250968A1 (fr)
CA (1) CA2492299A1 (fr)
DE (2) DE10232863A1 (fr)
DK (1) DK1521639T3 (fr)
ES (1) ES2252697T3 (fr)
WO (1) WO2004007085A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102010052312A1 (de) 2010-11-15 2012-05-16 Herbert Hüttlin Wirbelschichtapparatur mit Boden als Ventilator
DE102012007671A1 (de) 2012-04-16 2013-10-17 Acino Pharma Ag Pellets mit hohem Wirkstoffgehalt
EP4173720A1 (fr) 2021-10-29 2023-05-03 Romaco Innojet GmbH Buse de pulverisation

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DE202005003791U1 (de) 2005-02-28 2006-07-06 Hüttlin, Herbert, Dr. h.c. Apparatur zur Behandlung von partikelförmigem Gut
DE102005028168B3 (de) * 2005-06-17 2007-01-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Einrichtung zur Führung eines Gases für Vorrichtungen zum Behandeln körnigen Gutes durch Trocknen, Filmcoaten oder Beschichten, insbesondere Zulufteinheit und Vorrichtung mit einer derartigen Einrichtung
CN100387357C (zh) * 2005-11-25 2008-05-14 保定天威集团有限公司 环喷式喷头
DE102006019890B4 (de) 2006-04-28 2008-10-16 Dürr Systems GmbH Zerstäuber und zugehöriges Betriebsverfahren
DE102007013628A1 (de) * 2007-03-19 2008-09-25 Wurz, Dieter, Prof. Dr.-Ing. Rücklaufdüsen mit Druckluftunterstützung
DE102013013064A1 (de) 2013-08-06 2015-02-12 Acino Pharma Ag Prüf- und Reinigungsvorrichtung für Sprühdüsen
CN105013380A (zh) * 2015-06-24 2015-11-04 安徽东风机电科技股份有限公司 一种气粉掺混装置
DE102020000903B4 (de) * 2020-02-19 2021-12-09 Pieter Van Weenen & Co. Gmbh Aerosolisierungsvorrichtung
CN114130560B (zh) * 2021-12-06 2022-09-23 合肥工业大学 一种用于改良土壤的槐糖脂复配物及喷洒装置
CN115055017B (zh) * 2022-06-23 2023-08-04 重庆大学 斜向旋流式离心雾化喷淋装置

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102010052312A1 (de) 2010-11-15 2012-05-16 Herbert Hüttlin Wirbelschichtapparatur mit Boden als Ventilator
WO2012065931A1 (fr) 2010-11-15 2012-05-24 Herbert Huettlin Appareillage à lit fluidisé dont le fond sert de ventilateur
DE102012007671A1 (de) 2012-04-16 2013-10-17 Acino Pharma Ag Pellets mit hohem Wirkstoffgehalt
WO2013156088A1 (fr) 2012-04-16 2013-10-24 Acino Pharma Ag Pastilles à teneur élevée en principe actif
EP4173720A1 (fr) 2021-10-29 2023-05-03 Romaco Innojet GmbH Buse de pulverisation
DE102021128338A1 (de) 2021-10-29 2023-05-04 Romaco Innojet Gmbh Zerstäubungsdüse

Also Published As

Publication number Publication date
ES2252697T3 (es) 2006-05-16
CN100441310C (zh) 2008-12-10
ATE311257T1 (de) 2005-12-15
JP2006501048A (ja) 2006-01-12
DK1521639T3 (da) 2005-12-27
CA2492299A1 (fr) 2004-01-22
AU2003250968A1 (en) 2004-02-02
EP1521639A1 (fr) 2005-04-13
DE50301819D1 (de) 2006-01-05
DE10232863A1 (de) 2004-02-05
CN1668383A (zh) 2005-09-14
WO2004007085A1 (fr) 2004-01-22

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