EP1455778A4 - METHOD FOR THE TREATMENT OF PERIPHERAL NERVOUS AND VASCULAR DISEASES - Google Patents

METHOD FOR THE TREATMENT OF PERIPHERAL NERVOUS AND VASCULAR DISEASES

Info

Publication number
EP1455778A4
EP1455778A4 EP02789474A EP02789474A EP1455778A4 EP 1455778 A4 EP1455778 A4 EP 1455778A4 EP 02789474 A EP02789474 A EP 02789474A EP 02789474 A EP02789474 A EP 02789474A EP 1455778 A4 EP1455778 A4 EP 1455778A4
Authority
EP
European Patent Office
Prior art keywords
malays
methods
treating peripheral
neurovascular
peripheral neurovascular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP02789474A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP1455778A2 (en
Inventor
Richard A Rosenbloom
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Prophase Labs Inc
Original Assignee
Quigley Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2001/049297 external-priority patent/WO2002049575A2/en
Application filed by Quigley Corp filed Critical Quigley Corp
Publication of EP1455778A2 publication Critical patent/EP1455778A2/en
Publication of EP1455778A4 publication Critical patent/EP1455778A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/82—Theaceae (Tea family), e.g. camellia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35—Ketones, e.g. benzophenone
    • A61K8/355—Quinones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4986—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with sulfur as the only hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/602—Glycosides, e.g. rutin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/676—Ascorbic acid, i.e. vitamin C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/678—Tocopherol, i.e. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9771—Ginkgophyta, e.g. Ginkgoaceae [Ginkgo family]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/522—Antioxidants; Radical scavengers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Toxicology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
EP02789474A 2001-12-19 2002-11-06 METHOD FOR THE TREATMENT OF PERIPHERAL NERVOUS AND VASCULAR DISEASES Withdrawn EP1455778A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
WOPCT/US01/49297 2001-12-19
PCT/US2001/049297 WO2002049575A2 (en) 2000-12-21 2001-12-19 Method and composition for the treatment of diabetic neuropathy
PCT/US2002/035654 WO2003053336A2 (en) 2001-12-19 2002-11-06 Methods for the treatment of peripheral neural and vascular ailments

Publications (2)

Publication Number Publication Date
EP1455778A2 EP1455778A2 (en) 2004-09-15
EP1455778A4 true EP1455778A4 (en) 2007-09-12

Family

ID=21743140

Family Applications (1)

Application Number Title Priority Date Filing Date
EP02789474A Withdrawn EP1455778A4 (en) 2001-12-19 2002-11-06 METHOD FOR THE TREATMENT OF PERIPHERAL NERVOUS AND VASCULAR DISEASES

Country Status (8)

Country Link
EP (1) EP1455778A4 (enExample)
JP (1) JP2005518381A (enExample)
CA (1) CA2470603A1 (enExample)
IL (1) IL162505A0 (enExample)
MX (1) MXPA04006039A (enExample)
NZ (1) NZ533439A (enExample)
WO (1) WO2003053336A2 (enExample)
ZA (1) ZA200404614B (enExample)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2543404A1 (en) * 2003-10-24 2005-05-06 Meiji Seika Kaisha, Ltd. Novel inhibitor of the formation of advanced glycation end product and aldose reductase inhibitor
US7863248B2 (en) 2003-10-30 2011-01-04 Meiji Seika Kaisha, Ltd. Tyrosinase activity inhibitor and ameliorant for facial blood flow
US7678395B2 (en) 2003-11-05 2010-03-16 Osteoscreen, Inc. Stimulation of hair growth by isoginkgetin
JP2006083105A (ja) * 2004-09-16 2006-03-30 Ito En Ltd 血液流動性改善剤および飲食物
EP1907007A2 (en) * 2005-06-28 2008-04-09 KGK Synergize, Inc. Compositions to improve the bioavailability of polymethoxyflavones and tocotrienols for the treatment of cardiovascular disease
DE102005048778A1 (de) * 2005-10-10 2007-04-12 Beiersdorf Ag Kosmetische Formulierungen zur Verbesserung des Aussehens der Haut
DE102005048777A1 (de) * 2005-10-10 2007-04-12 Beiersdorf Ag Kosmetische Formulierungen zur Verbesserung der Mikrozirkulation der Haut
JP5132889B2 (ja) * 2006-02-27 2013-01-30 株式会社ポッカコーポレーション 神経成長因子増強剤
CA2648250A1 (en) * 2006-04-05 2007-10-18 Vertex Pharmaceuticals Incorporated Deazapurines useful as inhibitors of janus kinases
FR2904557B1 (fr) * 2006-08-01 2010-04-30 Pf Medicament Nouvel extrait d'eucalyptus, son procede de preparation et ses utilisations therapeutiques
GB0618168D0 (en) * 2006-09-15 2006-10-25 Babraham Inst Compounds
US20090060879A1 (en) * 2007-09-04 2009-03-05 The Procter & Gamble Company Oral Compositions, Products and Methods Of Use
AU2009274571A1 (en) * 2008-07-23 2010-01-28 Massachusetts Institute Of Technology Activation of histone deacetylase 1 (HDAC1) protects against DNA damage and increases neuronal survival
JP5415216B2 (ja) * 2009-10-02 2014-02-12 日本メナード化粧品株式会社 皮膚外用剤
CN102266320B (zh) * 2010-07-20 2015-06-17 浙江养生堂天然药物研究所有限公司 橙皮素的新用途
KR101021835B1 (ko) 2010-09-06 2011-03-17 충남대학교산학협력단 크리소스플레놀 시를 함유하는 심장 질환의 예방 및 치료용 조성물
CN102151281B (zh) * 2011-01-24 2014-03-26 中国药科大学 防治糖尿病的黄酮类化合物及其药物用途
WO2013016193A2 (en) 2011-07-22 2013-01-31 Massachusetts Istitute Of Technology Activators of class i histone deacetlyases (hdacs) and uses thereof
NZ596015A (en) * 2011-10-26 2014-04-30 Anzamed Internat Ltd Method and composition for the treatment of pain and/or inflammation
CN102526248B (zh) * 2012-03-22 2013-07-17 赵海潞 一种治疗糖尿病伤口溃烂并可持续降血糖的中药组合物
US20180193306A1 (en) 2012-03-23 2018-07-12 Cardero Therapeutics, Inc. Compounds and compositions for the treatment of muscular disorders and bone disorders
US9901564B2 (en) * 2012-03-23 2018-02-27 Cardero Therapeutics, Inc. Compounds and compositions for the treatment of muscular disorders
ITRM20120335A1 (it) * 2012-07-13 2014-01-14 Aboca Spa Societa Agricola Nuove composizioni per il trattamento del dolore neuropatico.
WO2014095289A2 (en) * 2012-12-20 2014-06-26 Unilever Plc Method of treating hair ageing
CN105431057A (zh) 2013-03-15 2016-03-23 雅培制药有限公司 维持和改善肌肉功能的方法
CN104547872A (zh) * 2015-01-30 2015-04-29 山东省立医院 一种治疗癫痫的中药组合物
CN107126437A (zh) * 2016-02-29 2017-09-05 上海中医药大学 一种槐角苷的药物用途
KR101828379B1 (ko) 2016-03-30 2018-02-12 우석대학교 산학협력단 해당화 꽃 추출물 또는 분획물을 유효성분으로 함유하는 기억력 개선, 인지능력 개선, 치매 예방, 지연, 개선 또는 치료용 조성물
KR101715294B1 (ko) * 2016-06-09 2017-03-10 연세대학교 산학협력단 디오스민 또는 이의 염을 유효성분으로 함유하는 피부보습 개선, 피부각질 제거, 피부탄력 증진, 홍반 억제, 피부주름 개선 또는 피부광노화 개선 효과를 갖는 조성물
WO2018078412A1 (en) * 2016-10-31 2018-05-03 Posi Visionary Solutions Llp Topical microemulsion of diosmetin and uses thereof
CN108164489B (zh) * 2018-03-20 2019-11-26 武汉轻工大学 一种高良姜素的制备方法
BR102018005599A2 (pt) * 2018-03-21 2019-10-08 Pedro Barboza Da Rocha Composição cicatrizante, hidratante, umectante e emoliente para administração tópica em lesões de pele intertrigo, lesões de pele por incontinência urinária e fecal e outras lesões afins.
WO2020051644A1 (en) * 2018-09-13 2020-03-19 Norbio No. 2 Pty Ltd Treatment of peripheral nervous tissue inflammation
CN112014480B (zh) * 2019-05-28 2023-03-28 黄河科技学院 一种uplc-ms/ms检测降脂宁颗粒中有效成分含量的方法
WO2021167012A1 (ja) * 2020-02-18 2021-08-26 国立大学法人筑波大学 神経機能調節用組成物
WO2022157381A1 (en) * 2021-01-25 2022-07-28 Universiteit Hasselt Phloretin for use in the treatment of neurodegenerative and demyelinating diseases
CN115317497A (zh) * 2022-01-13 2022-11-11 宁夏医科大学 甘草苷在制备胸主动脉血管舒张药物中的用途
CN114392256B (zh) * 2022-02-22 2023-05-09 中山大学附属第八医院（深圳福田） 矢车菊素在防治血管钙化中的应用
EP4622640A1 (en) * 2022-11-23 2025-10-01 Brightseed, Inc. Compositions and methods for modulating sleep and uses thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001076580A1 (fr) * 2000-04-11 2001-10-18 Takara Bio Inc. Remedes
WO2002049575A2 (en) * 2000-12-21 2002-06-27 The Quigley Corporation Method and composition for the treatment of diabetic neuropathy

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03232851A (ja) * 1989-12-26 1991-10-16 Nippon Flour Mills Co Ltd アルドース還元酵素阻害剤
JPH09235284A (ja) * 1995-02-23 1997-09-09 Nissan Chem Ind Ltd インドール系チアゾリジン類
IT1291113B1 (it) * 1997-03-20 1998-12-29 Sigma Tau Ind Farmaceuti Composizione nutritiva terapeutica per soggetti affetti da diabete mellito
IT1302307B1 (it) * 1998-09-01 2000-09-05 Sigma Tau Healthscience Spa Composizione ad attivita' antiossidante ed atta a migliorarel'utilizzazione metabolica del glucosio, comprendente acetil
JP4497566B2 (ja) * 1998-09-02 2010-07-07 株式会社 日本薬用食品研究所 アルドース還元酵素阻害剤並びに新規サポニン及び新規サポゲノール

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001076580A1 (fr) * 2000-04-11 2001-10-18 Takara Bio Inc. Remedes
EP1283037A1 (en) * 2000-04-11 2003-02-12 Takara Bio Inc. Remedies
WO2002049575A2 (en) * 2000-12-21 2002-06-27 The Quigley Corporation Method and composition for the treatment of diabetic neuropathy

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
SCHOEMAKER J H: "PHARMACOLOGICAL TREATMENT OF DIABETIC PERIPHERAL NEUROPATHY: CHALLENGES AND POSSIBILITIES", BRITISH JOURNAL OF CLINICAL PRACTICE, vol. 48, no. 2, 1994, pages 91 - 96, XP000878610, ISSN: 0007-0947 *
See also references of WO03053336A2 *
VARMA ET AL: "Flavonoids as Inhibitors of lens Aldose reductase.", SCIENCE, vol. 188, 1995 - 1995, pages 1215 - 1216, XP002431692 *

Also Published As

Publication number Publication date
NZ533439A (en) 2006-06-30
CA2470603A1 (en) 2003-07-03
ZA200404614B (en) 2005-08-29
MXPA04006039A (es) 2004-09-27
IL162505A0 (en) 2005-11-20
WO2003053336A3 (en) 2003-11-27
WO2003053336A2 (en) 2003-07-03
JP2005518381A (ja) 2005-06-23
AU2002352501A1 (en) 2003-07-09
EP1455778A2 (en) 2004-09-15

Similar Documents

Publication Publication Date Title
EP1455778A4 (en) METHOD FOR THE TREATMENT OF PERIPHERAL NERVOUS AND VASCULAR DISEASES
EP1565187A4 (en) METHOD FOR THE TREATMENT OF CANCER AND RELATED METHODS
NO20035156D0 (no) Fremgangsmåter for brönnbehandling
EP1601329A4 (en) AUTOMATIC SYSTEM FOR THE TREATMENT OF SILENTNESS
EP1501489A4 (en) COMBINATION THERAPY FOR THE TREATMENT OF CANCER
EP1423811A4 (en) TRANSACTION PROCESSING
FR2843295B1 (fr) Instrument pour le traitement de fracture de tassement de corps vertebraux
EP1446129A4 (en) POLYNUCLEOTIDE THERAPY
EP1575580A4 (en) METHOD FOR TREATING CARCINOMA
EP1300963A4 (en) ECHO-PROCESSING DEVICE
DE60217317D1 (de) Wärmebehandlungsverfahren
DE60218451D1 (de) 15-keto-prostaglandine zur behandlung arzneimittelinduzierter obstipation
EP1527196A4 (en) TREATMENT OF ASTHMA AND ALLERGIES
EP1429775A4 (en) METHOD FOR THE TREATMENT OF LUNG DISEASES
EP1359885A4 (en) NOS-HEMMER FOR THE TREATMENT OF WRINKLES
DE60227963D1 (de) Behandlungssystem
EP1461027A4 (en) TREATMENT OF NEOPLASIA
EP1389105A4 (en) Methods of Treatment
EP1401377A4 (en) METHOD FOR TREATING CANCER
NO20040087L (no) Fremgangsmate for behandling av sovnloshet
DE60233109D1 (de) Radidentifikator- ortungsverfahren
DZ3282A1 (fr) Traitement du psoriasis
EP1282411A4 (en) METHOD FOR THE TREATMENT OF CANCER
SE0301854L (sv) Antiigensättningsbehandling
IS6884A (is) Aðferðir við að nýta líffræðilegan fjölbreytileika

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20040609

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR

AX Request for extension of the european patent

Extension state: AL LT LV MK RO SI

A4 Supplementary search report drawn up and despatched

Effective date: 20070813

17Q First examination report despatched

Effective date: 20090317

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20101108