EP1346747B1 - Führungsdraht mit ablenkbarer Spitze - Google Patents
Führungsdraht mit ablenkbarer Spitze Download PDFInfo
- Publication number
- EP1346747B1 EP1346747B1 EP03251773A EP03251773A EP1346747B1 EP 1346747 B1 EP1346747 B1 EP 1346747B1 EP 03251773 A EP03251773 A EP 03251773A EP 03251773 A EP03251773 A EP 03251773A EP 1346747 B1 EP1346747 B1 EP 1346747B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- ribbon
- deflection
- steerable guidewire
- guidewire
- distal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/0105—Steering means as part of the catheter or advancing means; Markers for positioning
- A61M25/0133—Tip steering devices
- A61M25/0147—Tip steering devices with movable mechanical means, e.g. pull wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/0105—Steering means as part of the catheter or advancing means; Markers for positioning
- A61M25/0133—Tip steering devices
- A61M25/0152—Tip steering devices with pre-shaped mechanisms, e.g. pre-shaped stylets or pre-shaped outer tubes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
- A61M2025/0042—Microcatheters, cannula or the like having outside diameters around 1 mm or less
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/09058—Basic structures of guide wires
- A61M2025/09083—Basic structures of guide wires having a coil around a core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/09133—Guide wires having specific material compositions or coatings; Materials with specific mechanical behaviours, e.g. stiffness, strength to transmit torque
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/0105—Steering means as part of the catheter or advancing means; Markers for positioning
- A61M25/0133—Tip steering devices
- A61M25/0138—Tip steering devices having flexible regions as a result of weakened outer material, e.g. slots, slits, cuts, joints or coils
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M25/09016—Guide wires with mandrils
- A61M25/09033—Guide wires with mandrils with fixed mandrils, e.g. mandrils fixed to tip; Tensionable wires
Definitions
- the present invention relates to a steerable guidewire, and more particularly to a bi-directional steerable guidewire having a tip which may be very precisely "steered,” or deflected.
- the guidewire is particularly suitable for use in conjunction with the insertion of a catheter into a vessel of the body, or alternatively, the guidewire may be used by itself to open obstructions within a vessel or to carry a therapeutic device for removing obstructions within a vessel.
- guidewires have included a core wire with the distal end being tapered and with a coil spring mounted on the tapered distal end. These guidewires have been used to facilitate the insertion of a catheter into a vessel of the body. Generally, the guidewire is inserted into a vessel, a catheter is inserted over the guidewire and the catheter is then moved through the vessel until the distal end of the catheter is positioned at a desired location. The guidewire is then retracted from the catheter and the catheter is left in the vessel. Alternatively, the guidewire may be first inserted into the catheter with the distal portion of the guidewire extending beyond the distal end of the catheter.
- This assembly is then inserted into a vessel with the distal tip of the guidewire being used to facilitate movement of the guidewire and catheter through the vessel. Again, when the distal tip of the catheter has been placed in a desired location, the guidewire may be retracted thereby leaving the catheter in place within the vessel.
- Another common application for guidewires is that of using the distal tip of the guidewire for removing an obstruction within a vessel. Often times this procedure is accomplished by inserting the guidewire within a vessel, moving the distal tip of the guidewire into contact with the obstruction and then very gently tapping the distal tip of the guidewire against the obstruction until the guidewire passes through the obstruction.
- various types of devices may be placed on the distal end of a guidewire for actively opening an obstruction within the vessel. Examples of such devices which may be placed on the end of the guidewires are disclosed in the following United States Patents to Robert C. Stevens: 5,116,350; 5,078,722; 4,936,845; 4,923,462; and, 4,854,325.
- EP-A-0 377 269 discloses a bi-directional steerable catheter of the type set forth in the preamble of the accompanying claim 1.
- a bi-directional steerable guidewire having a deflectable tip which includes an elongated flexible tubing, a flexible helical coil attached to the distal portion of the flexible tubing, an elongated deflection member which is slidably disposed within the tubing and within the helical coil.
- the proximal portion of the deflection member may be of a cylindrical configuration.
- the distal portion is flattened to form a deflection ribbon which extends in a plane.
- a retaining ribbon is attached to the distal end of the flexible tubing and is oriented to extend in a plane which is generally parallel to the plane of the deflection ribbon.
- An attachment member which may take the form of a rounded bead, preferably formed from epoxy, engages the distal end of the helical coil, the distal end of the deflection ribbon and the distal end of the retaining ribbon so that longitudinal movement of the deflection member in a distal direction causes the distal end of the helical coil to be deflected in one direction and longitudinal movement of the deflection member in a proximal direction causes the distal end of the helical coil to be deflected in another opposite direction.
- the retaining ribbon and the deflection ribbon are normally biased in an arcuate configuration to thereby cause the distal end of the flexible helical coil to be biased into a normally curved shape.
- the distal portion of the deflection ribbon engages the attachment member, or rounded bead, at a location offset from the center of the attachment member, and the distal portion of the retaining ribbon engages the attachment member at a location offset from the center of the attachment member.
- the retaining ribbon engages the attachment member at a location offset from the center portion of the attachment member in the opposite direction from the offset location of the deflection ribbon.
- the deflection ribbon and the retaining ribbon are connected to each other within the attachment member.
- these two elements are formed as a single unitary element.
- the cylindrical deflection member is flattened to form the deflection ribbon and is further flattened at its distal end to form the retaining ribbon.
- the retaining ribbon is bent 180 degrees with respect to the deflection ribbon to form a generally U-shaped bend to thereby establish a predetermined spacing between the ribbons and to also cause these ribbons to remain parallel to each other.
- Figure 1 generally illustrates a steerable guidewire system 10 which embodies the present invention and comprises a steerable guidewire 12 coupled to a control handle 14. More particularly, the steerable guidewire comprises an elongated hypotube 16, a helical coil 18 attached to and extending from the distal end of the hypotube 16.
- the helical coil 18 is preferably formed from platinum tungsten with the proximal turns being wound such that adjacent turns of the proximal portion are in contact with each other.
- this element may take the form of any flexible cylindrical member, such as for example a thin metallic tube with or without portions of the tube removed by, for example laser cutting, so as to form a very flexible cylindrical member.
- An elongated deflection member 20 extends from the proximal end of the control handle through the hypotube 16 and through the helical coil 18, and is connected into an attachment member, or rounded bead 22, which is disposed at the distal tip of the helical coil 18.
- a retaining ribbon 24 is connected to the distal end of the hypotube 16 and is also connected to the rounded bead 22.
- the control handle 14 generally comprises a slidable control knob 26 which may be moved longitudinally with respect to the control handle.
- the control handle 14 is coupled to the deflection member 20.
- the longitudinal movement of the slidable control knob 26 causes deflection of the distal tip of the guidewire in either an upward or downward direction.
- Figures 2 and 3 illustrate in more detail the distal portion of the steerable guidewire 12.
- Figure 3 is a view of the guidewire 12 shown in Figure 2 with the guidewire being rotated 90 degrees about its longitudinal axis.
- the proximal end of the helical coil 18 is bonded, preferably by use of an epoxy, to the outer surface near the distal end of the hypotube 16.
- the elongated deflection member 20 takes the form of a small diameter cylindrical deflection member 20 having an intermediate portion which is flattened to form a thin deflection ribbon 34 having a thickness of approximately 50.8 ⁇ m (.002 inches).
- the distal end of the cylindrical deflection member 20 is further flattened to a thickness of approximately 38.1 ⁇ m (.0015 inches) and is bent back 180 degrees to form a U-shaped bend 26a between the deflection ribbon 34 and the retaining ribbon 24.
- the proximal end of the retaining ribbon 24 is bonded, preferably by use of epoxy, to the outer surface of the distal end of the hypotube 16.
- the retaining ribbon 24 is aligned in a plane parallel to the plane of the deflection ribbon 34 and the U-shaped portion between the ribbons is encapsulated by the attachment member which preferably takes the form of a rounded epoxy bead 22 bonded to the distal tip of the helical coil 18.
- the retaining ribbon 24 is preferably attached to the rounded bead 22 at a position offset from the center of the bead in the same direction that the retaining ribbon 24 is offset from the longitudinal axis of the steerable guidewire 12.
- the deflection ribbon 34 is attached to the bead at a position offset from the center of the bead in an opposite direction from the offset of the retaining ribbon 24.
- the deflection ribbon 34 and the retaining ribbon 24 are pre-shaped into an arcuate, or curved, configuration to thereby maintain the helical coil 18 in a normally curved configuration.
- the ribbons 24, 34 are pre-shaped such that the distal tip of the guidewire curves away from the longitudinal axis of the guidewire in a direction toward that side of the guidewire containing the retaining ribbon 24.
- Figure 4 illustrates in more detail the control handle 14 which includes a cylindrical body portion 38 with the slidable control knob 26 being mounted for longitudinal movement along the cylindrical body portion 38 of the control handle 14.
- the pair of set screws 28, 30 extend through the slidable control knob 26 and lock onto the elongated deflection member 20 which extends through the control handle 14.
- the control handle 14 includes a coaxial hypotube 40 which is disposed about the deflection member 20 and which is locked in place within the control handle by another set of set screws 32, 33.
- the coaxial hypotube 40 serves to prevent the deflection member 20 from buckling as the slidabte control knob is moved in a distal direction.
- the control handle 14 includes a pin vise 36 which serves to clamp onto the deflection member 20.
- the distal tip of the steerable guidewire 12 is normally biased into a downwardly curved position as illustrated in Figure 2 because of the curve of the pre-shaped deflection ribbon 34 and the retaining ribbon 24.
- the deflection member 20 will be moved distally thereby causing the deflection ribbon 34 to move in a distal direction.
- a force is applied to the top portion of the rounded bead 22.
- the retaining ribbon 24 is attached to the lower portion of the bead 22 to thereby maintain the bead at a fixed distance from the distal end of the hypotube 16.
- the tip of the guidewire is caused to deflect downwardly to a maximum position of deflection as shown in Figure 5A. Since the deflection ribbon 34 and the retaining ribbon 24 are pre-shaped prior to any activation of the steerable guidewire, the amount of force required to deflect the guidewire in this direction is very small thereby preventing buckling of the deflection ribbon 34 as the deflection ribbon is pushed distally. As the deflection ribbon 34 is moved distally, the upper turns of the helical coil become slightly stretched and the lower turns of the coil become slightly compressed.
- the deflection member 20 has a diameter of about 165.1 ⁇ m (.0065 inches) and the deflection ribbon has a thickness of about 50.8 ⁇ m (.002 inches) to thereby provide sufficient stiffness to prevent the buckling of these elements when the deflection member 20 is pushed distally. This construction also provides sufficient stiffness to transmit the necessary force to the distal tip of the guidewire.
- the deflection member 20 When the slidable control knob 26 is moved in a proximal direction (to the left in Figure 4) the deflection member 20 will be pulled to the left to thereby cause the deflection ribbon 34 to pull on the top portion of the bead 22. Since again the retaining ribbon 24 causes the lower portion of the bead to remain at a fixed distance from the distal end of the hypotube 16, the tip of the guidewire 12 is caused to bend in an upward direction to a maximum deflection as shown in Figure 5. Since the deflection ribbon 34 is in tension when the deflection member 20 is pulled, there is no concern for buckling of the deflection ribbon 34. As the deflection ribbon 34 is moved proximally as shown in Figure 5, the upper coil turns become slightly compressed and the lower coil turns become somewhat stretched.
- the elongated deflection member 20, retaining ribbon 24 and deflection ribbon 34 are constructed of nitinol, but these elements may be formed from other flexible materials including polymers.
- the helical coil 18 preferably has an outside coil diameter of about .013 inches and is constructed from an alloy comprised of about 92 percent platinum and 8 percent tungsten, but this element may also be constructed from numerous other materials. It is desirable that the coil exhibit the characteristic of being radiopaque to X-rays to assist in the positioning of the distal tip of the steerable guidewire 12.
- the deflection member 20 is formed from a single cylindrical nitinol wire of about 165.1 ⁇ m (.0065 inches) in diameter having an intermediate portion which is flattened to form the deflection ribbon 34 with a thickness of about 50.8 ⁇ m (.002 inches), and a distal portion which is flattened to form the retaining ribbon 24 with a thickness of about 38.1 ⁇ m (.0015 inches).
- the retaining ribbon 24 is bent back 180 degrees to form a generally U-shaped bend, which is subsequently encapsulated within the rounded bead 22.
- the rounded bead 22 is preferably formed with epoxy, but may be formed with soldering or by welding.
- the helical coil 18 is preferably coated with an elastomeric polymer 41 on its distal end to act as a sealant preventing the entry of blood and contrast media into the guidewire and a fluorinated polymer 39, such as Teflon (RTM), on its proximal end for lubrication purposes.
- the guidewire as disclosed may be very easily and very precisely deflected in either of two directions for very precise steering of the guidewire through the vessels of the body.
- the disclosed guidewire may be used for placement of a catheter within the vasculature of the human body, it may be used by itself to cross an obstruction within the vessels or it may be used to carry a therapeutic device mounted on the distal end of the guidewire for purposes of removing obstructions which may exist within a vessel of the body.
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Mechanical Engineering (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Surgical Instruments (AREA)
Claims (18)
- Bidirektionaler lenkbarer Führungsdraht (12) mit einer ablenkbaren Spitze, der folgendes aufweist:eine längliche flexible Röhre (16) mit einem proximalen und einem distalen Abschnitt; eine flexible Helixspule (18) mit einem proximalen und einem distalen Ende, wobei das proximale Ende der Helixspule an dem distalen Abschnitt der flexiblen Röhre angebracht ist;ein längliches Ablenkelement (20), das einen proximalen und einen distalen Abschnitt aufweist und gleitfähig in der Röhre (16) und in der Helixspule (18) angeordnet ist, wobei der distale Abschnitt des Ablenkelements abgeflacht ist, um ein Ablenkungsband (34) zu bilden, das sich in einer Ebene erstreckt;ein Halteband (24) mit einem proximalen und einem distalen Ende, wobei das proximale Ende des Haltebands an dem distalen Abschnitt der flexiblen Röhre (16) angebracht ist und das Halteband so ausgerichtet ist, daß es sich in einer Ebene erstreckt, die allgemein parallel zu der Ebene des Ablenkungsbands (34) ist; undein Befestigungselement (22), das an dem distalen Ende der Helixspule (18), dem distalen Abschnitt des Ablenkelements (20) und dem distalen Ende des Haltebands (24) angreift, so daß eine longitudinale Bewegung des Ablenkelements (20) in eine distale Richtung eine Ablenkung des distalen Endes Helixspule (18) in eine Richtung bewirkt und eine longitudinale Bewegung des Ablenkelements (20) in einer proximalen Richtung eine Ablenkung des distalen Endes Helixspule (18) in eine andere entgegengesetzte Richtung bewirkt,dadurch gekennzeichnet, daß das Halteband (24) und das Ablenkband (34) normalerweise in einer Bogenkonfiguration vorgespannt sind, um dabei zu bewirken, daß das distale Ende der Helixspule (18) normalerweise in einer gekrümmten Form vorgespannt ist.
- Lenkbarer Führungsdraht nach Anspruch 1, bei dem der proximale Abschnitt des Ablenkelements (20) einen runden Querschnitt aufweist, der sich von dem proximalen Abschnitt der flexiblen Röhre (16) zu etwa dem distalen Abschnitt der Röhre erstreckt.
- Lenkbarer Führungsdraht nach Anspruch 2, bei dem sich das proximale Ende des Haltebandes (24) von dem distalen Abschnitt der flexiblen Röhre (16) zu etwa dem distalen Ende der flexiblen Helixspule (18) erstreckt.
- Lenkbarer Führungsdraht nach einem der vorhergehenden Ansprüche, bei dem das Befestigungselement die Form eines abgerundeten Tropfens (22) annimmt.
- Lenkbarer Führungsdraht nach Anspruch 4, bei dem der abgerundete Tropfen (22) mit einem Epoxidmaterial gebildet ist.
- Lenkbarer Führungsdraht nach Anspruch 4 oder 5, bei dem der abgerundete Tropfen (22) das distale Ende der Helixspule (18) berührt, um eine runde Oberfläche an dem distalen Ende der Spule zu definieren, und das Halteband (34) an dem abgerundeten Tropfen an einem Ort angreift, der gegenüber der Mitte der kreisförmigen Oberfläche des abgerundeten Tropfens versetzt ist.
- Lenkbarer Führungsdraht nach Anspruch 7, bei dem das distale Ende des Haltebands (24) an dem abgerundeten Tropfen (22) an einem Ort angreift, der gegenüber der Mitte der kreisförmigen Oberfläche des abgerundeten Tropfens versetzt ist.
- Lenkbarer Führungsdraht nach Anspruch 7, bei dem das distale Ende des Haltebandes (24) an dem abgerundeten Tropfen (22) an einem Ort angreift, der gegenüber der Mitte der kreisförmigen Oberfläche in einer entgegengesetzten Richtung von dem versetzten Ort des Ablenkbands (34) versetzt ist.
- Lenkbarer Führungsdraht nach Anspruch 8, bei dem das Ablenkelement (20) und das Halteband (24) in dem abgerundeten Tropfen (22) miteinander verbunden sind.
- Lenkbarer Führungsdraht nach Anspruch 9, bei dem das Ablenkband (34) und das Halteband (24) aus einem einzelnen einheitlichen Element gebildet sind.
- Lenkbarer Führungsdraht nach Anspruch 10, bei dem das Ablenkband (34) und das Halteband (24) miteinander verbunden sind, um eine allgemein U-förmige Konfiguration zu bilden, um dabei einen vorbestimmten Abstand zwischen dem Ablenkband (34) und dem Halteband (24) vorzusehen und das Ablenkband und das Halteband in Ebenen zu halten, die zueinander parallel sind.
- Lenkbarer Führungsdraht nach Anspruch 11, bei dem das Ablenkband (34) durch Abflachen eines Zwischenabschnitts des Ablenkelements (20) gebildet ist und das Halteband durch Abflachen eines distalen Abschnitts des Ablenkelements (20) gebildet ist.
- Lenkbarer Führungsdraht nach Anspruch 12, bei dem das Halteband (24) eine Dicke aufweist, die geringer ist als die Dicke des Ablenkbands (34).
- Lenkbarer Führungsdraht nach Anspruch 13, bei dem das Ablenkband (34) eine Dicke von etwa 50,8 um (0,002 Zoll) und das Halteband (24) eine Dicke von etwa 38,1 µm (0,0015 Zoll) aufweist.
- Lenkbarer Führungsdraht nach einem der vorhergehenden Ansprüche, bei dem der proximale Abschnitt der länglichen flexiblen Röhre (16) mit einem Steuerhandstück (14) verbunden ist und das längliche Ablenkelement (20) an dem Steuerhandstück (14) für eine longitudinale Bewegung befestigt ist.
- Lenkbarer Führungsdraht nach Anspruch 15, bei dem das Steuerhandstück (14) einen beweglichen Griff (26) aufweist, der mit dem länglichen Ablenkelement (20) für die longitudinale Positionierung des Ablenkelements verbunden ist.
- Lenkbarer Führungsdraht nach Anspruch 16, bei dem das Steuerhandstück (14) mit der länglichen flexiblen Röhre (16) mit einem Lösemechanismus so verbunden ist, daß das Handstück von dem Führungsdraht (12) entfernt werden kann.
- Lenkbarer Führungsdraht nach Anspruch 17, bei dem sich das längliche Ablenkelement (20) durch die gesamte Länge des Steuerhandstücks (14) und über das proximale Ende des Steuerhandstücks hinaus erstreckt.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36673902P | 2002-03-22 | 2002-03-22 | |
US366739P | 2002-03-22 | ||
US224168 | 2002-08-20 | ||
US10/224,168 US7128718B2 (en) | 2002-03-22 | 2002-08-20 | Guidewire with deflectable tip |
Publications (3)
Publication Number | Publication Date |
---|---|
EP1346747A2 EP1346747A2 (de) | 2003-09-24 |
EP1346747A3 EP1346747A3 (de) | 2004-01-02 |
EP1346747B1 true EP1346747B1 (de) | 2006-08-16 |
Family
ID=27791388
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP03251773A Expired - Lifetime EP1346747B1 (de) | 2002-03-22 | 2003-03-21 | Führungsdraht mit ablenkbarer Spitze |
Country Status (4)
Country | Link |
---|---|
US (2) | US7128718B2 (de) |
EP (1) | EP1346747B1 (de) |
JP (1) | JP4583718B2 (de) |
DE (1) | DE60307533T2 (de) |
Cited By (2)
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US7351214B2 (en) | 2002-03-22 | 2008-04-01 | Cordis Corporation | Steerable balloon catheter |
US9549666B2 (en) | 2012-11-10 | 2017-01-24 | Curvo Medical, Inc. | Coaxial micro-endoscope |
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US6824550B1 (en) | 2000-04-06 | 2004-11-30 | Norbon Medical, Inc. | Guidewire for crossing occlusions or stenosis |
US9254143B2 (en) | 1998-02-25 | 2016-02-09 | Revascular Therapeutics, Inc. | Guidewire for crossing occlusions or stenoses having a shapeable distal end |
DE10105592A1 (de) | 2001-02-06 | 2002-08-08 | Achim Goepferich | Platzhalter zur Arzneistofffreigabe in der Stirnhöhle |
US20070213689A1 (en) * | 2002-03-22 | 2007-09-13 | Grewe David D | Deflectable tip infusion guidewire |
US7520863B2 (en) * | 2002-03-22 | 2009-04-21 | Cordis Corporation | Guidewire with deflectable tip having improved torque characteristics |
US8317816B2 (en) | 2002-09-30 | 2012-11-27 | Acclarent, Inc. | Balloon catheters and methods for treating paranasal sinuses |
US7758592B2 (en) | 2002-12-02 | 2010-07-20 | Wilson-Cook Medical Inc. | Loop tip wire guide |
DE602004027050D1 (de) * | 2003-08-07 | 2010-06-17 | Brivant Res & Dev Ltd | Führungsdraht für einen katheter |
AU2005229056A1 (en) * | 2004-03-24 | 2005-10-13 | Windcrest Llc | Vascular guidewire system |
US7615032B2 (en) * | 2004-03-24 | 2009-11-10 | Windcrest Llc | Vascular guidewire control apparatus |
US9351750B2 (en) | 2004-04-21 | 2016-05-31 | Acclarent, Inc. | Devices and methods for treating maxillary sinus disease |
US7654997B2 (en) | 2004-04-21 | 2010-02-02 | Acclarent, Inc. | Devices, systems and methods for diagnosing and treating sinusitus and other disorders of the ears, nose and/or throat |
US9554691B2 (en) | 2004-04-21 | 2017-01-31 | Acclarent, Inc. | Endoscopic methods and devices for transnasal procedures |
US20190314620A1 (en) | 2004-04-21 | 2019-10-17 | Acclarent, Inc. | Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures |
US20070167682A1 (en) | 2004-04-21 | 2007-07-19 | Acclarent, Inc. | Endoscopic methods and devices for transnasal procedures |
US7803150B2 (en) | 2004-04-21 | 2010-09-28 | Acclarent, Inc. | Devices, systems and methods useable for treating sinusitis |
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Publication number | Publication date |
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JP4583718B2 (ja) | 2010-11-17 |
DE60307533T2 (de) | 2007-05-03 |
US20060241519A1 (en) | 2006-10-26 |
JP2003325670A (ja) | 2003-11-18 |
EP1346747A2 (de) | 2003-09-24 |
EP1346747A3 (de) | 2004-01-02 |
US7128718B2 (en) | 2006-10-31 |
DE60307533D1 (de) | 2006-09-28 |
US20030181827A1 (en) | 2003-09-25 |
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