EP1175228A4 - GENE THERAPY USING TGF-BETA - Google Patents
GENE THERAPY USING TGF-BETAInfo
- Publication number
- EP1175228A4 EP1175228A4 EP00925522A EP00925522A EP1175228A4 EP 1175228 A4 EP1175228 A4 EP 1175228A4 EP 00925522 A EP00925522 A EP 00925522A EP 00925522 A EP00925522 A EP 00925522A EP 1175228 A4 EP1175228 A4 EP 1175228A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- tgf
- beta
- gene therapy
- therapy
- gene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1841—Transforming growth factor [TGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1019990015854A KR20000072904A (ko) | 1999-05-03 | 1999-05-03 | TGF-β분비세포를 포함하는 인대손상 치료 및 연골재생 촉진제 |
KR9915854 | 1999-05-03 | ||
US09/345,415 US6315992B1 (en) | 1999-06-30 | 1999-06-30 | Generating cartilage in a mammal using fibroblasts transfected with a vector encoding TGF-β-1 |
US345415 | 1999-06-30 | ||
PCT/IB2000/000653 WO2000066177A1 (en) | 1999-05-03 | 2000-05-03 | GENE THERAPY USING TGF-$g(b) |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1175228A1 EP1175228A1 (en) | 2002-01-30 |
EP1175228A4 true EP1175228A4 (en) | 2003-02-26 |
Family
ID=26635050
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00925522A Ceased EP1175228A4 (en) | 1999-05-03 | 2000-05-03 | GENE THERAPY USING TGF-BETA |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1175228A4 (zh) |
JP (3) | JP4592186B2 (zh) |
KR (1) | KR100702725B1 (zh) |
CN (2) | CN1371289B (zh) |
AU (1) | AU778047B2 (zh) |
CA (1) | CA2373045C (zh) |
WO (1) | WO2000066177A1 (zh) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2002243307A1 (en) * | 2000-11-08 | 2002-07-24 | Tissuegene, Inc. | Gene therapy using tgf-beta |
US20030175257A1 (en) * | 2002-03-12 | 2003-09-18 | Song Sun Uk | Cartilage regeneration using chondrocyte and TGF-beta |
US7005127B2 (en) * | 2002-03-29 | 2006-02-28 | Tissuegene, Inc. | Mixed-cell gene therapy |
AU2003251854A1 (en) * | 2002-07-09 | 2004-01-23 | Stryker Corporation | Compositions and methods for ligament growth and repair |
CN100394989C (zh) * | 2002-11-15 | 2008-06-18 | 华沙整形外科股份有限公司 | 包含微粒状基于胶原材料的组合物的制药应用和包含所述组合物的滑膜关节 |
WO2005073365A1 (ja) * | 2004-01-29 | 2005-08-11 | Japan Tissue Engineering Co., Ltd. | 移植用細胞の処理方法、細胞懸濁液、移植用補綴物、および損傷部位の治療方法 |
JP6125751B2 (ja) * | 2008-03-21 | 2017-05-10 | ティシュージーン,インク. | 椎間板変性症の治療 |
JP5388233B2 (ja) * | 2011-01-19 | 2014-01-15 | 富士ソフト株式会社 | 再生軟骨の軟骨特性を評価する方法 |
US10793625B2 (en) * | 2012-05-01 | 2020-10-06 | The Johns Hopkins University | Compositions and methods for treating or preventing osteoarthritis |
WO2015035395A1 (en) * | 2013-09-09 | 2015-03-12 | Figene, Llc | Gene therapy for the regeneration of chondrocytes or cartilage type cells |
KR20190003414A (ko) * | 2017-06-30 | 2019-01-09 | 코오롱생명과학 주식회사 | 세포치료제의 유효성 평가 방법 |
CN113372432A (zh) * | 2021-06-15 | 2021-09-10 | 深圳市臻质医疗科技有限公司 | 一种基于化学修饰mRNA编码蛋白因子诱导和/或增强软骨损伤修复的方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5858355A (en) * | 1990-12-20 | 1999-01-12 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | IRAP gene as treatment for arthritis |
US6315992B1 (en) * | 1999-06-30 | 2001-11-13 | Tissuegene Co. | Generating cartilage in a mammal using fibroblasts transfected with a vector encoding TGF-β-1 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6413511B1 (en) * | 1990-12-20 | 2002-07-02 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Cartilage alterations by administering to joints chondrocytes comprising a heterologous polynucleotide |
US5869041A (en) * | 1996-01-12 | 1999-02-09 | The Miriam Hospital | Delivery of bioactive compounds to an organism |
US6077987A (en) * | 1997-09-04 | 2000-06-20 | North Shore-Long Island Jewish Research Institute | Genetic engineering of cells to enhance healing and tissue regeneration |
DK2075002T3 (da) * | 1998-05-01 | 2013-05-21 | Univ Pittsburgh | Myoblaster til reparation af urinvejslukkemuskel |
-
2000
- 2000-05-03 CN CN008070741A patent/CN1371289B/zh not_active Expired - Lifetime
- 2000-05-03 CA CA2373045A patent/CA2373045C/en not_active Expired - Lifetime
- 2000-05-03 JP JP2000615060A patent/JP4592186B2/ja not_active Expired - Lifetime
- 2000-05-03 EP EP00925522A patent/EP1175228A4/en not_active Ceased
- 2000-05-03 WO PCT/IB2000/000653 patent/WO2000066177A1/en not_active Application Discontinuation
- 2000-05-03 CN CN2010105280759A patent/CN101972275A/zh active Pending
- 2000-05-03 KR KR1020017013987A patent/KR100702725B1/ko active IP Right Grant
- 2000-05-03 AU AU44242/00A patent/AU778047B2/en not_active Expired
-
2006
- 2006-07-18 JP JP2006195771A patent/JP4188986B2/ja not_active Expired - Lifetime
-
2008
- 2008-07-04 JP JP2008176059A patent/JP4547446B2/ja not_active Expired - Lifetime
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5858355A (en) * | 1990-12-20 | 1999-01-12 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | IRAP gene as treatment for arthritis |
US6315992B1 (en) * | 1999-06-30 | 2001-11-13 | Tissuegene Co. | Generating cartilage in a mammal using fibroblasts transfected with a vector encoding TGF-β-1 |
Non-Patent Citations (1)
Title |
---|
See also references of WO0066177A1 * |
Also Published As
Publication number | Publication date |
---|---|
CA2373045A1 (en) | 2000-11-09 |
CA2373045C (en) | 2016-07-26 |
WO2000066177A1 (en) | 2000-11-09 |
KR100702725B1 (ko) | 2007-04-03 |
CN1371289A (zh) | 2002-09-25 |
EP1175228A1 (en) | 2002-01-30 |
KR20020036943A (ko) | 2002-05-17 |
JP2002542801A (ja) | 2002-12-17 |
JP2009019039A (ja) | 2009-01-29 |
JP4547446B2 (ja) | 2010-09-22 |
JP4188986B2 (ja) | 2008-12-03 |
JP2007008950A (ja) | 2007-01-18 |
JP4592186B2 (ja) | 2010-12-01 |
AU778047B2 (en) | 2004-11-11 |
CN101972275A (zh) | 2011-02-16 |
CN1371289B (zh) | 2013-03-20 |
AU4424200A (en) | 2000-11-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20011130 |
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AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
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AX | Request for extension of the european patent |
Free format text: AL;LT;LV;MK;RO;SI |
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A4 | Supplementary search report drawn up and despatched |
Effective date: 20030115 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: 7C 07K 14/495 B Ipc: 7A 61K 38/18 B Ipc: 7A 61K 48/00 A |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: TISSUEGENE, INC. |
|
17Q | First examination report despatched |
Effective date: 20040205 |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED |
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18R | Application refused |
Effective date: 20061107 |
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