EP1143948A3 - Antagoniste des glucocorticoides, specifique du foie, pour le traitement du diabete - Google Patents
Antagoniste des glucocorticoides, specifique du foie, pour le traitement du diabeteInfo
- Publication number
- EP1143948A3 EP1143948A3 EP99925232A EP99925232A EP1143948A3 EP 1143948 A3 EP1143948 A3 EP 1143948A3 EP 99925232 A EP99925232 A EP 99925232A EP 99925232 A EP99925232 A EP 99925232A EP 1143948 A3 EP1143948 A3 EP 1143948A3
- Authority
- EP
- European Patent Office
- Prior art keywords
- liver
- treating diabetes
- selective glucocorticoid
- glucocorticoid antagonist
- antagonist
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9812314.4A GB9812314D0 (en) | 1998-06-08 | 1998-06-08 | Treatment of diabetes |
GB9812314 | 1998-06-08 | ||
GB9815149 | 1998-07-13 | ||
GBGB9815149.1A GB9815149D0 (en) | 1998-07-13 | 1998-07-13 | Treatment of diabetes |
PCT/IB1999/001175 WO1999063976A2 (fr) | 1998-06-08 | 1999-06-07 | Traitement de diabetes |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1143948A2 EP1143948A2 (fr) | 2001-10-17 |
EP1143948A3 true EP1143948A3 (fr) | 2002-09-11 |
Family
ID=26313822
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP99925232A Withdrawn EP1143948A3 (fr) | 1998-06-08 | 1999-06-07 | Antagoniste des glucocorticoides, specifique du foie, pour le traitement du diabete |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1143948A3 (fr) |
JP (1) | JP2002527355A (fr) |
KR (1) | KR20010052431A (fr) |
AU (1) | AU751569B2 (fr) |
CA (1) | CA2334116A1 (fr) |
IL (1) | IL139865A0 (fr) |
WO (1) | WO1999063976A2 (fr) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9816935D0 (en) * | 1998-08-05 | 1998-09-30 | Karobio Ab | Novel glucocortoid and thyroid receptor ligands for the treatment of metabolic disorders |
GB9907048D0 (en) * | 1999-03-27 | 1999-05-19 | Karobio Ab | Novel glucocorticoid receptor ligands for the treatment of meta bolic disorders |
GB9928805D0 (en) * | 1999-12-07 | 2000-02-02 | Karobio Ab | Compounds active at the Glucocorticoid and Thyroid Hormone Receptors |
ATE303369T1 (de) | 2000-10-30 | 2005-09-15 | Pfizer Prod Inc | Glucocorticoid rezeptor modulatoren |
GB0029102D0 (en) | 2000-11-29 | 2001-01-10 | Karobio Ab | Compounds active at the glucocorticoid receptor |
GB0029100D0 (en) * | 2000-11-29 | 2001-01-10 | Karobio Ab | Compounds active at the glucocorticoid receptor |
WO2002049634A2 (fr) * | 2000-12-20 | 2002-06-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Antagonistes du recepteur glucocorticoide dissocies permettant le traitement des effets secondaires lies au glucocorticoide |
JP4499357B2 (ja) * | 2001-02-14 | 2010-07-07 | カロ・バイオ・アー・ベー | 糖質コルチコイド受容体調節剤 |
US6583180B2 (en) | 2001-02-14 | 2003-06-24 | Abbott Laboratories | Glucocorticoid receptor modulators |
EP1285927A3 (fr) | 2001-08-16 | 2005-06-29 | Schering Aktiengesellschaft | Utilisation d'antagonistes du récepteur glucocorticoide pour la prévention et traitement des maladies de la fonction reproductive masculine |
EP1572126A4 (fr) * | 2001-12-21 | 2006-07-05 | Smithkline Beecham Corp | Compositions et methodes servant a modifier la production de glucose |
AU2003218342B8 (en) | 2002-03-26 | 2008-07-31 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
US7186864B2 (en) | 2002-05-29 | 2007-03-06 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
US7074806B2 (en) | 2002-06-06 | 2006-07-11 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
US8097606B2 (en) | 2003-07-23 | 2012-01-17 | Corcept Therapeutics, Inc. | Antiglucocorticoids for the treatment of catatonia |
WO2005012961A1 (fr) | 2003-07-31 | 2005-02-10 | Soken Chemical & Engineering Co., Ltd. | Cristal colloidal fluide et procede de production de masse de particules tridimensionnelles alignees a partir de ce cristal |
UY28526A1 (es) | 2003-09-24 | 2005-04-29 | Boehringer Ingelheim Pharma | Miméticos de glucocorticoides, métodos de preparación composiciones farmacéuticas y usos de los mismos |
US7795272B2 (en) | 2004-03-13 | 2010-09-14 | Boehringer Ingelheim Pharmaceutical, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof |
EP1836166B1 (fr) | 2004-12-27 | 2009-06-17 | Boehringer Ingelheim Pharmaceuticals Inc. | Composes mimetiques glucocorticoides, compositions pharmaceutiques les contenant, et methodes de fabrication et d'utilisation de ceux-ci |
EP2102170A2 (fr) | 2006-12-06 | 2009-09-23 | Boehringer Ingelheim International GmbH | Substances mimétiques de glucocorticoïde, procédés de préparation de celles-ci, compositions pharmaceutiques et utilisations de celles-ci |
SI2300472T1 (sl) | 2008-06-06 | 2012-05-31 | Boehringer Ingelheim Int | Glukokortikoidni mimetiki postopki za njihovo pripravo farmacevtski sestavki in njihove uporabe |
US8138189B2 (en) * | 2009-03-26 | 2012-03-20 | Hoffman-La Roche Inc. | Substituted benzene compounds as modulators of the glucocorticoid receptor |
SG178174A1 (en) | 2009-07-31 | 2012-03-29 | Cadila Healthcare Ltd | Novel compounds as modulators of glucocorticoid receptors |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4374148A (en) * | 1980-10-21 | 1983-02-15 | Pfizer Inc. | Carboxylic acid therapeutic agents |
US5929058A (en) * | 1996-12-24 | 1999-07-27 | Zymogenetics, Inc. | Treatment agents and methods for treating type II diabetes and symptoms of type II diabetes |
-
1999
- 1999-06-07 JP JP2000553045A patent/JP2002527355A/ja active Pending
- 1999-06-07 CA CA002334116A patent/CA2334116A1/fr not_active Abandoned
- 1999-06-07 KR KR1020007013430A patent/KR20010052431A/ko not_active Application Discontinuation
- 1999-06-07 IL IL13986599A patent/IL139865A0/xx unknown
- 1999-06-07 AU AU41606/99A patent/AU751569B2/en not_active Ceased
- 1999-06-07 EP EP99925232A patent/EP1143948A3/fr not_active Withdrawn
- 1999-06-07 WO PCT/IB1999/001175 patent/WO1999063976A2/fr not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO1999063976A2 (fr) | 1999-12-16 |
CA2334116A1 (fr) | 1999-12-16 |
EP1143948A2 (fr) | 2001-10-17 |
AU751569B2 (en) | 2002-08-22 |
JP2002527355A (ja) | 2002-08-27 |
AU4160699A (en) | 1999-12-30 |
KR20010052431A (ko) | 2001-06-25 |
WO1999063976A3 (fr) | 2001-12-20 |
IL139865A0 (en) | 2002-02-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP1143948A3 (fr) | Antagoniste des glucocorticoides, specifique du foie, pour le traitement du diabete | |
AU8693098A (en) | Compositions and methods for treating diabetes | |
AU5497098A (en) | Remedies for diabetes | |
AU2863899A (en) | New compounds | |
AU7582398A (en) | Composition for treating skin conditions | |
AU3901100A (en) | Method and composition for waterproofing | |
AU3077699A (en) | Apparatus for performing hippotherapy | |
AU4562697A (en) | Setting composition for well operations | |
AU1952601A (en) | Estrogens for treating als | |
AU9750398A (en) | D-homo-9,10-secocholesta-23-yne-3,25-diol derivatives | |
AU3170099A (en) | Remedies for obesity | |
AU5651799A (en) | Remedies for photochemotherapy | |
AUPP433398A0 (en) | Compounds and processes | |
AU3344399A (en) | Remedies for primary biliary cirrhosis | |
IL131059A (en) | DUAL PURPOSE INPUT ELECTRODE STRUCTURE FOR MIOCs | |
AU3556199A (en) | Improved methods for making hormone heterodimers | |
HK1024175A1 (en) | Plasters for percutaneous absorption | |
AU2333099A (en) | Aryloxyanilides and related compounds | |
AU4809000A (en) | Method and composition for waterproofing | |
AU3455000A (en) | Composition for decomposing protein | |
AU5891599A (en) | Mixer | |
AU2863799A (en) | New compounds | |
AU6487298A (en) | Underwear for men | |
AU7624000A (en) | Wrist-worn radiotelephone arrangement | |
AU8386098A (en) | Orthopedic supports |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20001221 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
XX | Miscellaneous (additional remarks) |
Free format text: DERZEIT SIND DIE WIPO-PUBLIKATIONSDATEN A3 NICHT VERFUEGBAR. |
|
PUAK | Availability of information related to the publication of the international search report |
Free format text: ORIGINAL CODE: 0009015 |
|
AK | Designated contracting states |
Kind code of ref document: A3 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
17Q | First examination report despatched |
Effective date: 20030211 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20030822 |